Functions and Diseases

RBP Type Non-canonical_RBPs
Diseases CancerSARS-COV-OC43FlavivirusesHIVSARS-COV-2SINVVEEVDengue
Drug Drug
Main interacting RNAs N.A.
Moonlighting functions N.A.
Localizations N.A.
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000204388 Gene ID 3304 Accession 5233
Symbol HSPA1B Alias HSP72;HSPA1;HSX70;HSP70-1;HSP70-2;HSP70.1;HSP70.2;HSP70-1B Full Name heat shock protein family A (Hsp70) member 1B
Status Confidence Length 2517 bases Strand Plus strand
Position 6 : 31827738 - 31830254 RNA binding domain N.A.
Summary This intronless gene encodes a 70kDa heat shock protein which is a member of the heat shock protein 70 family. In conjuction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. It is also involved in the ubiquitin-proteasome pathway through interaction with the AU-rich element RNA-binding protein 1. The gene is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which encode similar proteins. [provided by RefSeq, Jul 2008]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal
33600380 Prognostic Significance of the Hsp70 Gene Family in Colorectal Cancer. Wenjun Jiang 2021-02-18 Medical science monitor : international medical journal of experimental and clinical research
36824771 mRNA interactions with disordered regions control protein activity. Yang Luo 2023-02-18 bioRxiv : the preprint server for biology

Transcripts

Name Transcript ID bp Protein Translation ID

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID
12997Diabetes Mellitus, Type 13.26E-9919430480
13266Lupus Erythematosus, Systemic8.14E-618204446
59850Hypertension9.2230137E-006-

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000204388homo_sapiensENSP00000364802100100homo_sapiensENSP00000364801100100
ENSG00000204388homo_sapiensENSP0000032417377.064261.0092homo_sapiensENSP0000036480178.627162.2465
ENSG00000204388homo_sapiensENSP0000036762357.170936.1493homo_sapiensENSP0000036480145.397828.7051
ENSG00000204388homo_sapiensENSP0000028566754.989436.9427homo_sapiensENSP0000036480140.405627.1451
ENSG00000204388homo_sapiensENSP0000029718562.886646.8336homo_sapiensENSP0000036480166.614749.61
ENSG00000204388homo_sapiensENSP0000048015032.932918.4184homo_sapiensENSP0000036480151.326128.7051
ENSG00000204388homo_sapiensENSP0000036480594.539889.2356homo_sapiensENSP0000036480194.539889.2356
ENSG00000204388homo_sapiensENSP0000024720790.453883.0986homo_sapiensENSP0000036480190.171682.8393
ENSG00000204388homo_sapiensENSP0000031021990.668781.493homo_sapiensENSP0000036480190.951681.7473
ENSG00000204388homo_sapiensENSP0000030296142.023826.0714homo_sapiensENSP0000036480155.070234.1654
ENSG00000204388homo_sapiensENSP0000031868739.160824.5921homo_sapiensENSP0000036480152.418132.9173
ENSG00000204388homo_sapiensENSP0000043208392.105384.8297homo_sapiensENSP0000036480192.823785.4914
ENSG00000204388homo_sapiensENSP0000029646442.550725.5066homo_sapiensENSP0000036480155.694233.3853
ENSG00000204388homo_sapiensENSP0000044278999.844299.8442homo_sapiensENSP00000364801100100
ENSG00000204388homo_sapiensENSP00000403530100100homo_sapiensENSP00000364801100100
ENSG00000204388homo_sapiensENSP0000038769199.844299.8442homo_sapiensENSP00000364801100100
ENSG00000204388homo_sapiensENSP0000040265199.844299.8442homo_sapiensENSP00000364801100100

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000204388homo_sapiensENSP00000364801100100pongo_abeliiENSPPYP00000018408100100
ENSG00000204388homo_sapiensENSP00000364801100100pan_troglodytesENSPTRP0000006016499.68999.689
ENSG00000204388homo_sapiensENSP0000036480112.01257.02028sarcophilus_harrisiiENSSHAP0000003287738.308522.3881
ENSG00000204388homo_sapiensENSP0000036480193.447782.2153notamacropus_eugeniiENSMEUP0000001218593.012481.8323
ENSG00000204388homo_sapiensENSP0000036480187.363579.8752notamacropus_eugeniiENSMEUP0000000499687.227479.7508
ENSG00000204388homo_sapiensENSP0000036480188.455582.0593erinaceus_europaeusENSEEUP0000000699988.180481.804
ENSG00000204388homo_sapiensENSP0000036480198.283996.7239echinops_telfairiENSETEP0000000763098.283996.7239
ENSG00000204388homo_sapiensENSP0000036480199.84499.844callithrix_jacchusENSCJAP0000005584992.888292.8882
ENSG00000204388homo_sapiensENSP0000036480199.84499.844macaca_fascicularisENSMFAP0000000808096.82396.823
ENSG00000204388homo_sapiensENSP00000364801100100macaca_mulattaENSMMUP0000007219699.844299.8442
ENSG00000204388homo_sapiensENSP0000036480199.2298.2839tursiops_truncatusENSTTRP0000001340699.2298.2839
ENSG00000204388homo_sapiensENSP0000036480198.90898.2839vulpes_vulpesENSVVUP0000003048098.753998.1308
ENSG00000204388homo_sapiensENSP0000036480161.934559.2824mus_spretusMGP_SPRETEiJ_P004625883.932480.3383
ENSG00000204388homo_sapiensENSP0000036480161.778559.1264mus_spretusMGP_SPRETEiJ_P004625995.421791.3253
ENSG00000204388homo_sapiensENSP0000036480199.53298.908equus_asinusENSEASP0000504738792.732692.1512
ENSG00000204388homo_sapiensENSP0000036480199.06497.9719loxodonta_africanaENSLAFP0000002291498.909797.8193
ENSG00000204388homo_sapiensENSP0000036480199.53299.064panthera_leoENSPLOP0000000979095.223994.7761
ENSG00000204388homo_sapiensENSP0000036480173.634973.3229ailuropoda_melanoleucaENSAMEP0000001988599.159798.7395
ENSG00000204388homo_sapiensENSP0000036480199.37698.908bos_indicus_hybridENSBIXP0000501454197.549897.0904
ENSG00000204388homo_sapiensENSP0000036480197.659993.4477oryctolagus_cuniculusENSOCUP0000001957591.923687.9589
ENSG00000204388homo_sapiensENSP0000036480192.355787.9875oryctolagus_cuniculusENSOCUP0000000719096.890392.3077
ENSG00000204388homo_sapiensENSP0000036480188.923685.9594equus_caballusENSECAP0000002699584.19581.3885
ENSG00000204388homo_sapiensENSP0000036480199.68898.908canis_lupus_familiarisENSCAFP0084501805595.089394.3452
ENSG00000204388homo_sapiensENSP0000036480121.684921.2168panthera_pardusENSPPRP0000002025693.918991.8919
ENSG00000204388homo_sapiensENSP0000036480173.79173.4789panthera_pardusENSPPRP0000002571299.369898.9496
ENSG00000204388homo_sapiensENSP0000036480199.53299.064panthera_pardusENSPPRP0000002911199.53299.064
ENSG00000204388homo_sapiensENSP0000036480199.2298.752marmota_marmota_marmotaENSMMMP0000001165199.2298.752
ENSG00000204388homo_sapiensENSP0000036480173.478973.0109balaenoptera_musculusENSBMSP0001002403798.949698.3193
ENSG00000204388homo_sapiensENSP0000036480199.2298.2839balaenoptera_musculusENSBMSP0001002408299.2298.2839
ENSG00000204388homo_sapiensENSP0000036480199.2298.2839balaenoptera_musculusENSBMSP0001002399899.37598.4375
ENSG00000204388homo_sapiensENSP0000036480198.75296.8799cavia_porcellusENSCPOP0000002049098.75296.8799
ENSG00000204388homo_sapiensENSP0000036480194.851894.0718felis_catusENSFCAP0000004194198.064597.2581
ENSG00000204388homo_sapiensENSP0000036480199.37699.064ursus_americanusENSUAMP0000003198397.549897.2435
ENSG00000204388homo_sapiensENSP0000036480192.979790.7956monodelphis_domesticaENSMODP0000000717382.548580.6094
ENSG00000204388homo_sapiensENSP0000036480167.082766.6147monodon_monocerosENSMMNP0001500654899.53798.8426
ENSG00000204388homo_sapiensENSP0000036480191.419790.4836monodon_monocerosENSMMNP0001500051999.659998.6395
ENSG00000204388homo_sapiensENSP0000036480199.53298.4399sus_scrofaENSSSCP0000005889197.256196.189
ENSG00000204388homo_sapiensENSP0000036480198.75296.7239octodon_degusENSODEP0000002704898.75296.7239
ENSG00000204388homo_sapiensENSP0000036480198.75296.7239octodon_degusENSODEP0000002704498.75296.7239
ENSG00000204388homo_sapiensENSP0000036480198.595996.2559jaculus_jaculusENSJJAP0000000816798.595996.2559
ENSG00000204388homo_sapiensENSP0000036480198.595996.2559jaculus_jaculusENSJJAP0000000866898.595996.2559
ENSG00000204388homo_sapiensENSP0000036480173.478973.3229ovis_aries_rambouilletENSOARP0002001594498.949698.7395
ENSG00000204388homo_sapiensENSP0000036480199.2298.752ovis_aries_rambouilletENSOARP0002001588599.2298.752
ENSG00000204388homo_sapiensENSP0000036480199.37699.064ursus_maritimusENSUMAP0000001827394.230893.9349
ENSG00000204388homo_sapiensENSP0000036480199.37698.4399delphinapterus_leucasENSDLEP0000002237088.718787.883
ENSG00000204388homo_sapiensENSP0000036480173.634973.3229physeter_catodonENSPCTP0000501526199.159798.7395
ENSG00000204388homo_sapiensENSP0000036480199.2298.5959physeter_catodonENSPCTP0000501520499.2298.5959
ENSG00000204388homo_sapiensENSP0000036480198.127994.8518mus_caroliMGP_CAROLIEiJ_P004436198.127994.8518
ENSG00000204388homo_sapiensENSP0000036480197.971994.6958mus_caroliMGP_CAROLIEiJ_P004436398.12594.8438
ENSG00000204388homo_sapiensENSP0000036480198.283995.1638mus_musculusENSMUSP0000013381598.130895.0156
ENSG00000204388homo_sapiensENSP0000036480198.283995.1638mus_musculusENSMUSP0000008458698.283995.1638
ENSG00000204388homo_sapiensENSP0000036480195.631890.0156dipodomys_ordiiENSDORP0000001935396.535490.8661
ENSG00000204388homo_sapiensENSP0000036480195.319889.8596dipodomys_ordiiENSDORP0000001882795.319889.8596
ENSG00000204388homo_sapiensENSP0000036480194.071893.4477mustela_putorius_furoENSMPUP0000001072693.925293.3022
ENSG00000204388homo_sapiensENSP0000036480159.438452.1061aotus_nancymaaeENSANAP0000001250386.394675.737
ENSG00000204388homo_sapiensENSP0000036480199.2298.752vicugna_pacosENSVPAP0000000162698.911498.4448
ENSG00000204388homo_sapiensENSP00000364801100100chlorocebus_sabaeusENSCSAP00000018820100100
ENSG00000204388homo_sapiensENSP0000036480199.37698.4399phocoena_sinusENSPSNP0000003114158.872558.3179
ENSG00000204388homo_sapiensENSP0000036480148.361946.4899camelus_dromedariusENSCDRP0000501377683.783880.5405
ENSG00000204388homo_sapiensENSP0000036480111.856511.8565camelus_dromedariusENSCDRP0000501571479.166779.1667
ENSG00000204388homo_sapiensENSP0000036480173.010972.8549carlito_syrichtaENSTSYP0000002982398.526398.3158
ENSG00000204388homo_sapiensENSP0000036480199.53299.064panthera_tigris_altaicaENSPTIP0000000826799.53299.064
ENSG00000204388homo_sapiensENSP0000036480198.595996.5679rattus_norvegicusENSRNOP0000007559992.532990.6296
ENSG00000204388homo_sapiensENSP0000036480198.90898.2839prolemur_simusENSPSMP0000002627984.084983.5544
ENSG00000204388homo_sapiensENSP0000036480198.283995.6318microtus_ochrogasterENSMOCP0000000605398.283995.6318
ENSG00000204388homo_sapiensENSP0000036480156.474354.6022sorex_araneusENSSARP0000000104556.739854.8589
ENSG00000204388homo_sapiensENSP0000036480195.163892.3557peromyscus_maniculatus_bairdiiENSPEMP0000000488494.867892.0684
ENSG00000204388homo_sapiensENSP0000036480198.439995.6318peromyscus_maniculatus_bairdiiENSPEMP0000000483398.286695.4829
ENSG00000204388homo_sapiensENSP0000036480197.971997.5039bos_mutusENSBMUP0000000552899.210198.7362
ENSG00000204388homo_sapiensENSP0000036480193.135792.6677bos_mutusENSBMUP0000000547899.666199.1653
ENSG00000204388homo_sapiensENSP0000036480193.447790.0156mus_spicilegusENSMSIP0000001917995.230591.7329
ENSG00000204388homo_sapiensENSP0000036480180.343278.9392cricetulus_griseus_chok1gshdENSCGRP0000100137499.038597.3077
ENSG00000204388homo_sapiensENSP0000036480199.06498.4399pteropus_vampyrusENSPVAP0000001152799.06498.4399
ENSG00000204388homo_sapiensENSP0000036480198.439996.8799myotis_lucifugusENSMLUP0000000443792.657991.1894
ENSG00000204388homo_sapiensENSP0000036480198.439997.1919myotis_lucifugusENSMLUP0000001779488.128587.0112
ENSG00000204388homo_sapiensENSP0000036480199.06497.6599rhinolophus_ferrumequinumENSRFEP0001000383592.162690.8563
ENSG00000204388homo_sapiensENSP0000036480199.37698.908bos_taurusENSBTAP0000001750099.37698.908
ENSG00000204388homo_sapiensENSP0000036480198.595996.5679heterocephalus_glaber_femaleENSHGLP0000004377398.595996.5679
ENSG00000204388homo_sapiensENSP0000036480199.68898.908canis_lupus_dingoENSCAFP0002002648194.526693.787
ENSG00000204388homo_sapiensENSP0000036480199.37698.908sciurus_vulgarisENSSVLP0000502107796.369195.9153
ENSG00000204388homo_sapiensENSP0000036480196.099894.0718phascolarctos_cinereusENSPCIP0000001024395.800993.7792
ENSG00000204388homo_sapiensENSP0000036480193.447792.3557procavia_capensisENSPCAP0000001288399.008397.8512
ENSG00000204388homo_sapiensENSP0000036480198.595997.8159bos_grunniensENSBGRP0000002751698.904598.1221
ENSG00000204388homo_sapiensENSP0000036480192.043790.3276chinchilla_lanigeraENSCLAP0000002587298.993397.1477
ENSG00000204388homo_sapiensENSP0000036480170.202870.0468cervus_hanglu_yarkandensisENSCHYP0000001533099.118998.8987
ENSG00000204388homo_sapiensENSP0000036480194.071892.9797catagonus_wagneriENSCWAP0000002736799.177698.0263
ENSG00000204388homo_sapiensENSP0000036480199.2298.752ictidomys_tridecemlineatusENSSTOP0000001823799.2298.752
ENSG00000204388homo_sapiensENSP0000036480199.2298.752ictidomys_tridecemlineatusENSSTOP0000001178799.2298.752
ENSG00000204388homo_sapiensENSP0000036480198.90898.4399otolemur_garnettiiENSOGAP0000002254598.600398.1338
ENSG00000204388homo_sapiensENSP0000036480198.90898.4399otolemur_garnettiiENSOGAP0000001775698.600398.1338
ENSG00000204388homo_sapiensENSP0000036480164.430664.1186urocitellus_parryiiENSUPAP0001002556165.451765.1347
ENSG00000204388homo_sapiensENSP0000036480198.439997.9719moschus_moschiferusENSMMSP0000002122298.439997.9719
ENSG00000204388homo_sapiensENSP0000036480148.049945.2418mus_pahariMGP_PahariEiJ_P004390197.468491.7721
ENSG00000204388homo_sapiensENSP0000036480137.597535.2574mus_pahariMGP_PahariEiJ_P004390296.490.4
ENSG00000204388homo_sapiensENSP0000036480181.903368.6427caenorhabditis_elegansF44E5.5.181.395368.2171
ENSG00000204388homo_sapiensENSP0000036480181.903368.6427caenorhabditis_elegansF44E5.4.181.395368.2171
ENSG00000204388homo_sapiensENSP0000036480181.903366.9267caenorhabditis_elegansC12C8.1.181.648566.7185
ENSG00000204388homo_sapiensENSP0000036480147.581928.5491caenorhabditis_elegansC30C11.4.139.304123.5825
ENSG00000204388homo_sapiensENSP0000036480151.794129.9532drosophila_melanogasterFBpp029299939.712922.9665
ENSG00000204388homo_sapiensENSP0000036480150.54631.6693ciona_intestinalisENSCINP0000000165438.617424.1955
ENSG00000204388homo_sapiensENSP0000036480116.848716.0686callorhinchus_miliiENSCMIP0000000309192.307788.0342
ENSG00000204388homo_sapiensENSP0000036480111.388510.9204carassius_auratusENSCARP0000005481077.659674.4681
ENSG00000204388homo_sapiensENSP0000036480113.260513.1045ictalurus_punctatusENSIPUP0000001909492.391391.3043
ENSG00000204388homo_sapiensENSP0000036480119.344817.1607electrophorus_electricusENSEEEP0000003818481.045871.8954
ENSG00000204388homo_sapiensENSP0000036480111.388510.1404oncorhynchus_kisutchENSOKIP0000507802179.347870.6522
ENSG00000204388homo_sapiensENSP0000036480115.912614.0406gadus_morhuaENSGMOP0000006651082.258172.5806
ENSG00000204388homo_sapiensENSP0000036480114.508612.4805gadus_morhuaENSGMOP0000005847985.321173.3945
ENSG00000204388homo_sapiensENSP0000036480111.38858.89236gadus_morhuaENSGMOP0000005857267.592652.7778
ENSG00000204388homo_sapiensENSP0000036480119.500817.1607fundulus_heteroclitusENSFHEP0000002095983.333373.3333
ENSG00000204388homo_sapiensENSP0000036480138.689535.7254fundulus_heteroclitusENSFHEP0000003289186.111179.5139
ENSG00000204388homo_sapiensENSP0000036480182.371365.6786chrysemys_picta_belliiENSCPBP0000001042381.860565.2713
ENSG00000204388homo_sapiensENSP0000036480172.698958.0343chrysemys_picta_belliiENSCPBP0000001508370.286656.1086
ENSG00000204388homo_sapiensENSP0000036480170.514858.0343sphenodon_punctatusENSSPUP0000000156079.858765.7244
ENSG00000204388homo_sapiensENSP0000036480172.074954.4462crocodylus_porosusENSCPRP0000500440172.755954.9606
ENSG00000204388homo_sapiensENSP0000036480171.450951.4821notechis_scutatusENSNSUP0000001079475.577654.4554
ENSG00000204388homo_sapiensENSP0000036480174.41553.1981pseudonaja_textilisENSPTXP0000001380576.56554.7352
ENSG00000204388homo_sapiensENSP0000036480173.94752.7301naja_najaENSNNAP0000002430675.477753.8217
ENSG00000204388homo_sapiensENSP0000036480174.41558.8144podarcis_muralisENSPMRP0000002785279.235962.6246
ENSG00000204388homo_sapiensENSP0000036480138.845635.2574oryzias_javanicusENSOJAP0000000148987.062979.021
ENSG00000204388homo_sapiensENSP000003648015.616222.18409amphilophus_citrinellusENSACIP0000002558629.752111.5702
ENSG00000204388homo_sapiensENSP0000036480114.508612.7925dicentrarchus_labraxENSDLAP0000507210375.609866.6667
ENSG00000204388homo_sapiensENSP0000036480170.982855.8502pelodiscus_sinensisENSPSIP0000000164778.313361.6179
ENSG00000204388homo_sapiensENSP0000036480172.542958.0343gopherus_evgoodeiENSGEVP0000500698172.09357.6744
ENSG00000204388homo_sapiensENSP0000036480133.853427.6131chelonoidis_abingdoniiENSCABP0000001310377.224262.9893
ENSG00000204388homo_sapiensENSP0000036480168.174751.4821struthio_camelus_australisENSSCUP0000002618970.483953.2258
ENSG00000204388homo_sapiensENSP0000036480182.059365.2106terrapene_carolina_triunguisENSTMTP0000000434582.187565.3125
ENSG00000204388homo_sapiensENSP0000036480133.697327.4571terrapene_carolina_triunguisENSTMTP0000001716376.868362.6335
ENSG00000204388homo_sapiensENSP0000036480113.260512.0125pygocentrus_nattereriENSPNAP0000001331371.428664.7059
ENSG00000204388homo_sapiensENSP0000036480137.441535.4134pygocentrus_nattereriENSPNAP0000002192587.591282.8467
ENSG00000204388homo_sapiensENSP0000036480149.14231.3573ciona_savignyiENSCSAVP0000001760635.353522.5589
ENSG00000204388homo_sapiensENSP0000036480142.745723.5569saccharomyces_cerevisiaeYPL106C39.538221.7893
ENSG00000204388homo_sapiensENSP0000036480143.681724.805saccharomyces_cerevisiaeYBR169C40.40422.9437
ENSG00000204388homo_sapiensENSP0000036480138.533535.5694stegastes_partitusENSSPAP0000000330580.194874.026
ENSG00000204388homo_sapiensENSP0000036480118.876816.2246nothobranchius_furzeriENSNFUP0001504803682.876771.2329
ENSG00000204388homo_sapiensENSP0000036480126.833125.117nothobranchius_furzeriENSNFUP000150480278074.8837
ENSG00000204388homo_sapiensENSP0000036480114.196612.9485cyprinodon_variegatusENSCVAP0000002171977.777870.9402
ENSG00000204388homo_sapiensENSP0000036480115.912615.6006sinocyclocheilus_grahamiENSSGRP0000009266882.926881.3008
ENSG00000204388homo_sapiensENSP0000036480120.124818.5647paramormyrops_kingsleyaeENSPKIP0000003465879.141173.0061
ENSG00000204388homo_sapiensENSP0000036480110.60849.67239leptobrachium_leishanenseENSLLEP0000000092758.119752.9915
ENSG00000204388homo_sapiensENSP0000036480111.07649.9844oryzias_melastigmaENSOMEP0000002622072.44965.3061

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0001618enables virus receptor activity1IEAHomo_sapiens(9606)Function
GO:0001664enables G protein-coupled receptor binding1IDAHomo_sapiens(9606)Function
GO:0003723enables RNA binding1HDAHomo_sapiens(9606)Function
GO:0005102enables signaling receptor binding1IPIHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005524enables ATP binding1IDAHomo_sapiens(9606)Function
GO:0005576located_in extracellular region1TASHomo_sapiens(9606)Component
GO:0005634is_active_in nucleus2IBA,IDAHomo_sapiens(9606)Component
GO:0005654located_in nucleoplasm1TASHomo_sapiens(9606)Component
GO:0005737is_active_in cytoplasm3IBA,IDA,TASHomo_sapiens(9606)Component
GO:0005739located_in mitochondrion1TASHomo_sapiens(9606)Component
GO:0005783located_in endoplasmic reticulum1TASHomo_sapiens(9606)Component
GO:0005813located_in centrosome1IDAHomo_sapiens(9606)Component
GO:0005814located_in centriole1IDAHomo_sapiens(9606)Component
GO:0005829located_in cytosol2IDA,TASHomo_sapiens(9606)Component
GO:0005925located_in focal adhesion1HDAHomo_sapiens(9606)Component
GO:0006402involved_in mRNA catabolic process1IDAHomo_sapiens(9606)Process
GO:0008285involved_in negative regulation of cell population proliferation1IMPHomo_sapiens(9606)Process
GO:0010628involved_in positive regulation of gene expression1IMPHomo_sapiens(9606)Process
GO:0016234located_in inclusion body1IDAHomo_sapiens(9606)Component
GO:0016235located_in aggresome1IDAHomo_sapiens(9606)Component
GO:0016607located_in nuclear speck1IDAHomo_sapiens(9606)Component
GO:0016887enables ATP hydrolysis activity3IBA,IDA,TASHomo_sapiens(9606)Function
GO:0019899enables enzyme binding1IPIHomo_sapiens(9606)Function
GO:0030308involved_in negative regulation of cell growth1IMPHomo_sapiens(9606)Process
GO:0031072enables heat shock protein binding2IBA,IPIHomo_sapiens(9606)Function
GO:0031396involved_in regulation of protein ubiquitination1IDAHomo_sapiens(9606)Process
GO:0031397involved_in negative regulation of protein ubiquitination1IDAHomo_sapiens(9606)Process
GO:0031625enables ubiquitin protein ligase binding2IBA,IPIHomo_sapiens(9606)Function
GO:0031982located_in vesicle1HDAHomo_sapiens(9606)Component
GO:0032436involved_in positive regulation of proteasomal ubiquitin-dependent protein catabolic process1IBAHomo_sapiens(9606)Process
GO:0032757involved_in positive regulation of interleukin-8 production1IMPHomo_sapiens(9606)Process
GO:0032991part_of protein-containing complex1IDAHomo_sapiens(9606)Component
GO:0034599involved_in cellular response to oxidative stress1TASHomo_sapiens(9606)Process
GO:0034605involved_in cellular response to heat1IDAHomo_sapiens(9606)Process
GO:0042026involved_in protein refolding3IBA,IDA,IMPHomo_sapiens(9606)Process
GO:0042826enables histone deacetylase binding1IPIHomo_sapiens(9606)Function
GO:0043066involved_in negative regulation of apoptotic process2IMP,TASHomo_sapiens(9606)Process
GO:0044183enables protein folding chaperone2IBA,IDAHomo_sapiens(9606)Function
GO:0045648involved_in positive regulation of erythrocyte differentiation1IMPHomo_sapiens(9606)Process
GO:0046034involved_in ATP metabolic process1IDAHomo_sapiens(9606)Process
GO:0046718involved_in viral entry into host cell1IEAHomo_sapiens(9606)Process
GO:0048471located_in perinuclear region of cytoplasm1IDAHomo_sapiens(9606)Component
GO:0050821involved_in protein stabilization2IMP,TASHomo_sapiens(9606)Process
GO:0051082enables unfolded protein binding3IDA,NAS,TASHomo_sapiens(9606)Function
GO:0051085involved_in chaperone cofactor-dependent protein refolding1IBAHomo_sapiens(9606)Process
GO:0051092involved_in positive regulation of NF-kappaB transcription factor activity1IMPHomo_sapiens(9606)Process
GO:0055131enables C3HC4-type RING finger domain binding1IPIHomo_sapiens(9606)Function
GO:0070062located_in extracellular exosome1HDAHomo_sapiens(9606)Component
GO:0070370involved_in cellular heat acclimation1IMPHomo_sapiens(9606)Process
GO:0070434involved_in positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway1IMPHomo_sapiens(9606)Process
GO:0071383involved_in cellular response to steroid hormone stimulus1TASHomo_sapiens(9606)Process
GO:0072562located_in blood microparticle1HDAHomo_sapiens(9606)Component
GO:0090063involved_in positive regulation of microtubule nucleation1IMPHomo_sapiens(9606)Process
GO:0090084involved_in negative regulation of inclusion body assembly1IDAHomo_sapiens(9606)Process
GO:0140545enables ATP-dependent protein disaggregase activity1IDAHomo_sapiens(9606)Function
GO:0140662enables ATP-dependent protein folding chaperone1IEAHomo_sapiens(9606)Function
GO:1901673involved_in regulation of mitotic spindle assembly2IBA,IMPHomo_sapiens(9606)Process
GO:1903265involved_in positive regulation of tumor necrosis factor-mediated signaling pathway1IMPHomo_sapiens(9606)Process
GO:1904813located_in ficolin-1-rich granule lumen1TASHomo_sapiens(9606)Component
GO:1990904part_of ribonucleoprotein complex1IDAHomo_sapiens(9606)Component
GO:2001240involved_in negative regulation of extrinsic apoptotic signaling pathway in absence of ligand1IMPHomo_sapiens(9606)Process

Expression