RBPWorld - a comprehensive database of RNA Binding Proteins

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RBP World!

Functions and Diseases

RBP Type	Non-canonical_RBPs
Diseases	N.A.
Drug	N.A.
Main interacting RNAs	N.A.
Moonlighting functions	N.A.
Localizations	N.A.
BulkPerturb-seq

Description

Ensembl ID	ENSG00000198924	Gene ID	9937	Accession	17660
Symbol	DCLRE1A	Alias	PSO2;SNM1;SNM1A	Full Name	DNA cross-link repair 1A
Status	Confidence	Length	19659 bases	Strand	Minus strand
Position	10 : 113834725 - 113854383	RNA binding domain	N.A.
Summary	This gene encodes a conserved protein that is involved in the repair of DNA interstrand cross-links. DNA cross-links suppress transcription, replication, and DNA segregation. The encoded protein is a regulator of the mitotic cell cycle checkpoint. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2012]

RNA binding domains (RBDs)

Protein	Domain	Pfam ID	E-value	Domain number

RNA binding proteomes (RBPomes)

Pubmed ID	Full Name	Cell	Author	Time	Doi

Literatures on RNA binding capacity

Pubmed ID	Title	Author	Time	Journal

Transcripts

Name	Transcript ID	bp	Protein	Translation ID
DCLRE1A-201	ENST00000361384	4450	1040aa	ENSP00000355185
DCLRE1A-202	ENST00000369305	4241	1040aa	ENSP00000358311
DCLRE1A-203	ENST00000476112	707	No protein	-

Gene Model

Click here to download ENSG00000198924's gene model file

Pathways

Pathway ID	Pathway Name	Source

Phenotypes

ensgID	Trait	pValue	Pubmed ID

GWAS

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Protein-Protein Interaction (PPI)

Click here to download ENSG00000198924's PPI file

Paralogs

Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Orthologs

Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Gene Ontology

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0001650	located_in fibrillar center	1	IDA	Homo_sapiens(9606)	Component
GO:0003684	enables damaged DNA binding	1	IBA	Homo_sapiens(9606)	Function
GO:0005654	located_in nucleoplasm	2	IDA,TAS	Homo_sapiens(9606)	Component
GO:0006303	involved_in double-strand break repair via nonhomologous end joining	1	IBA	Homo_sapiens(9606)	Process
GO:0007049	involved_in cell cycle	1	IEA	Homo_sapiens(9606)	Process
GO:0008800	enables beta-lactamase activity	1	IDA	Homo_sapiens(9606)	Function
GO:0035312	enables 5-3 DNA exonuclease activity	2	IBA,IDA	Homo_sapiens(9606)	Function
GO:0036297	involved_in interstrand cross-link repair	1	IBA	Homo_sapiens(9606)	Process
GO:0046872	enables metal ion binding	1	IEA	Homo_sapiens(9606)	Function
GO:0051301	involved_in cell division	1	IEA	Homo_sapiens(9606)	Process

Expression