RBP Type
Non-canonical_RBPs
Diseases
N.A.
Drug
N.A.
Main interacting RNAs
N.A.
Moonlighting functions
N.A.
Localizations
Nucleoli
BulkPerturb-seq
Ensembl ID ENSG00000198830 Gene ID
3151
Accession
4986
Symbol
HMGN2
Alias
HMG17
Full Name
high mobility group nucleosomal binding domain 2
Status
Confidence
Length
4203 bases
Strand
Plus strand
Position
1 : 26472440 - 26476642
RNA binding domain
N.A.
Summary
The protein encoded by this gene binds nucleosomal DNA and is associated with transcriptionally active chromatin. Along with a similar protein, HMGN1, the encoded protein may help maintain an open chromatin configuration around transcribable genes. The protein has also been found to have antimicrobial activity against bacteria, viruses and fungi. [provided by RefSeq, Oct 2014]
RNA binding domains (RBDs)
Protein
Domain
Pfam ID
E-value
Domain number
RNA binding proteomes (RBPomes)
Pubmed ID
Full Name
Cell
Author
Time
Doi
Literatures on RNA binding capacity
Pubmed ID
Title
Author
Time
Journal
Name
Transcript ID
bp
Protein
Translation ID
HMGN2-201
ENST00000361427
1940
90aa
ENSP00000355228
HMGN2-207
ENST00000468388
320
No protein
-
HMGN2-208
ENST00000479815
1030
No protein
-
HMGN2-202
ENST00000460563
1045
No protein
-
HMGN2-204
ENST00000464888
565
No protein
-
HMGN2-203
ENST00000463817
853
No protein
-
HMGN2-206
ENST00000467700
932
No protein
-
HMGN2-205
ENST00000466194
952
No protein
-
HMGN2-209
ENST00000493418
1496
No protein
-
Pathway ID
Pathway Name
Source
ensgID
Trait
pValue
Pubmed ID
43034 Platelet Function Tests 1.3666700E-005 - 45187 Platelet Function Tests 1.8267700E-005 -
ensgID SNP Chromosome Position
Trait PubmedID Or or BEAT
EFO ID
Protein-Protein Interaction (PPI)
Ensembl ID
Source
Target
Species
Protein ID
Perc_pos
Perc_id
Species
Protein ID
Perc_pos
Perc_id
Ensembl ID
Source
Target
Species
Protein ID
Perc_pos
Perc_id
Species
Protein ID
Perc_pos
Perc_id
Go ID
Go term
No. evidence
Entries
Species
Category
GO:0000785 part_of chromatin 1 IEA Homo_sapiens(9606) Component GO:0003682 enables chromatin binding 1 IBA Homo_sapiens(9606) Function GO:0003723 enables RNA binding 1 HDA Homo_sapiens(9606) Function GO:0005515 enables protein binding 1 IPI Homo_sapiens(9606) Function GO:0005615 located_in extracellular space 1 IDA Homo_sapiens(9606) Component GO:0005634 is_active_in nucleus 2 IBA,IDA Homo_sapiens(9606) Component GO:0005737 located_in cytoplasm 1 IDA Homo_sapiens(9606) Component GO:0006325 involved_in chromatin organization 1 IBA Homo_sapiens(9606) Process GO:0031492 enables nucleosomal DNA binding 1 IEA Homo_sapiens(9606) Function GO:0031640 involved_in killing of cells of another organism 1 IMP Homo_sapiens(9606) Process GO:0061844 involved_in antimicrobial humoral immune response mediated by antimicrobial peptide 1 IMP Homo_sapiens(9606) Process
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