Functions and Diseases

RBP Type Canonical_RBPs
Diseases SARS-COV-2
Drug N.A.
Main interacting RNAs mRNA
Moonlighting functions N.A.
Localizations N.A.
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000198692 Gene ID 9086 Accession 3252
Symbol EIF1AY Alias eIF-4C Full Name eukaryotic translation initiation factor 1A Y-linked
Status Confidence Length 17379 bases Strand Plus strand
Position Y : 20575776 - 20593154 RNA binding domain eIF-1a
Summary This gene is located on the non-recombining region of the Y chromosome. It encodes a protein related to eukaryotic translation initiation factor 1A (EIF1A), which may function in stabilizing the binding of the initiator Met-tRNA to 40S ribosomal subunits. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000354722 eIF-1a PF01176 6.8e-21 1
ENSP00000372222 eIF-1a PF01176 1.3e-09 1

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal

Transcripts

Name Transcript ID bp Protein Translation ID
EIF1AY-201 ENST00000361365 1339 144aa ENSP00000354722
EIF1AY-204 ENST00000465253 855 No protein -
EIF1AY-202 ENST00000382772 746 127aa ENSP00000372222
EIF1AY-203 ENST00000464196 3148 No protein -
EIF1AY-205 ENST00000485584 641 No protein -

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000198692homo_sapiensENSP0000036892710099.3056homo_sapiensENSP0000035472210099.3056

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000198692homo_sapiensENSP0000035472210099.3056pan_troglodytesENSPTRP0000003879710099.3056
ENSG00000198692homo_sapiensENSP0000035472288.194488.1944cercocebus_atysENSCATP00000009841100100
ENSG00000198692homo_sapiensENSP00000354722100100macaca_fascicularisENSMFAP00000049349100100
ENSG00000198692homo_sapiensENSP00000354722100100macaca_mulattaENSMMUP00000045488100100
ENSG00000198692homo_sapiensENSP00000354722100100papio_anubisENSPANP00000038817100100
ENSG00000198692homo_sapiensENSP0000035472288.194486.1111mandrillus_leucophaeusENSMLEP0000003868210097.6378
ENSG00000198692homo_sapiensENSP0000035472286.111186.1111ailuropoda_melanoleucaENSAMEP00000027789100100
ENSG00000198692homo_sapiensENSP0000035472277.083375aotus_nancymaaeENSANAP0000002274199.107196.4286
ENSG00000198692homo_sapiensENSP00000354722100100chlorocebus_sabaeusENSCSAP00000014326100100
ENSG00000198692homo_sapiensENSP0000035472278.472277.0833nannospalax_galiliENSNGAP0000001354298.260996.5217
ENSG00000198692homo_sapiensENSP00000354722100100cebus_imitatorENSCCAP00000006226100100
ENSG00000198692homo_sapiensENSP00000354722100100rhinopithecus_roxellanaENSRROP00000004196100100
ENSG00000198692homo_sapiensENSP0000035472281.2570.8333caenorhabditis_elegansH06H21.3.154.166747.2222
ENSG00000198692homo_sapiensENSP0000035472288.194479.8611drosophila_melanogasterFBpp031041885.810877.7027
ENSG00000198692homo_sapiensENSP0000035472290.277878.4722ciona_intestinalisENSCINP0000001287769.148960.1064
ENSG00000198692homo_sapiensENSP0000035472296.527893.75eptatretus_burgeriENSEBUP0000001287296.527893.75
ENSG00000198692homo_sapiensENSP00000354722100100chrysemys_picta_belliiENSCPBP00000007790100100
ENSG00000198692homo_sapiensENSP00000354722100100sphenodon_punctatusENSSPUP00000024147100100
ENSG00000198692homo_sapiensENSP00000354722100100crocodylus_porosusENSCPRP00005005768100100
ENSG00000198692homo_sapiensENSP00000354722100100notechis_scutatusENSNSUP00000016790100100
ENSG00000198692homo_sapiensENSP00000354722100100pseudonaja_textilisENSPTXP00000008852100100
ENSG00000198692homo_sapiensENSP0000035472295.833395.8333meleagris_gallopavoENSMGAP00000015536100100
ENSG00000198692homo_sapiensENSP0000035472298.611196.5278serinus_canariaENSSCAP0000001986292.207890.2597
ENSG00000198692homo_sapiensENSP00000354722100100naja_najaENSNNAP00000020009100100
ENSG00000198692homo_sapiensENSP0000035472295.138995.1389podarcis_muralisENSPMRP00000010395100100
ENSG00000198692homo_sapiensENSP0000035472297.916796.5278geospiza_fortisENSGFOP0000001575997.241495.8621
ENSG00000198692homo_sapiensENSP0000035472210099.3056taeniopygia_guttataENSTGUP0000000774243.373543.0723
ENSG00000198692homo_sapiensENSP0000035472297.222297.2222pelodiscus_sinensisENSPSIP0000000521297.902197.9021
ENSG00000198692homo_sapiensENSP00000354722100100gopherus_evgoodeiENSGEVP00005003347100100
ENSG00000198692homo_sapiensENSP00000354722100100chelonoidis_abingdoniiENSCABP00000002122100100
ENSG00000198692homo_sapiensENSP0000035472297.916797.9167struthio_camelus_australisENSSCUP0000001072495.270395.2703
ENSG00000198692homo_sapiensENSP00000354722100100strigops_habroptilaENSSHBP00005021308100100
ENSG00000198692homo_sapiensENSP00000354722100100terrapene_carolina_triunguisENSTMTP00000006864100100
ENSG00000198692homo_sapiensENSP00000354722100100terrapene_carolina_triunguisENSTMTP00000017023100100
ENSG00000198692homo_sapiensENSP0000035472262.552.7778ciona_savignyiENSCSAVP0000000832561.643852.0548
ENSG00000198692homo_sapiensENSP0000035472280.555665.9722saccharomyces_cerevisiaeYMR260C75.81762.0915
ENSG00000198692homo_sapiensENSP00000354722100100aquila_chrysaetos_chrysaetosENSACCP00020005644100100

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0000049enables tRNA binding1IEAHomo_sapiens(9606)Function
GO:0003743enables translation initiation factor activity1IBAHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005737is_active_in cytoplasm1IBAHomo_sapiens(9606)Component
GO:0006413involved_in translational initiation1IBAHomo_sapiens(9606)Process

Expression