RBPWorld - a comprehensive database of RNA Binding Proteins

Functions and Diseases

RBP Type	Canonical_RBPs
Diseases	SARS-COV-2DengueZika
Drug	Drug
Main interacting RNAs	rRNA
Moonlighting functions	Metabolic enzyme
Localizations	Nucleoli
BulkPerturb-seq	N.A.

Description

Ensembl ID	ENSG00000197728	Gene ID	6231	Accession	10414
Symbol	RPS26	Alias	S26;eS26;DBA10	Full Name	ribosomal protein S26
Status	Confidence	Length	3347 bases	Strand	Plus strand
Position	12 : 56041351 - 56044697	RNA binding domain	Ribosomal_S26e
Summary	This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S26E family of ribosomal proteins. Mutations in this gene are found in Diamond-Blackfan anemia 10. There are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Aug 2017]

RNA binding domains (RBDs)

Search:

Protein	Domain	Pfam ID	E-value	Domain number
ENSP00000348849	Ribosomal_S26e	PF01283	1.9e-54	1
ENSP00000450339	Ribosomal_S26e	PF01283	1.9e-54	1
ENSP00000496643	Ribosomal_S26e	PF01283	1.9e-54	1

Showing 1 to 3 of 3 entries

RNA binding proteomes (RBPomes)

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Pubmed ID	Full Name	Cell	Author	Time	Doi
22658674	RIC_PMID22658674_Hela_human	Hela	Alfredo Castello	2012 Jun 8	doi: 10.1016/j.cell.2012.04.031.?Epub 2012 May 31
22658674	RIC_PMID22658674_Hs_HeLa	HeLa	Alfredo Castello?	2012 Jun 8	doi: 10.1016/j.cell.2012.04.031.?Epub 2012 May 31
22681889	RIC_PMID22681889_Hs_HEK293	HEK293	Alexander G Baltz	2012 Jun 8	doi: 10.1016/j.molcel.2012.05.021
25173706	Pclap_PMID25173706_Hs_HEK293	HEK293	Katharina Kramer	2014 Oct;11	doi: 10.1038/nmeth.3092.?Epub 2014 Aug 31
25843628	ChIRP.MS_PMID25843628_Hela_human	Hela	Ci Chu	2015 Apr 9	doi: 10.1016/j.cell.2015.03.025.?Epub 2015 Apr 2
26632259	RIC_PMID26632259._Hs_HuH7	HuH7	Benedikt M Beckmann	2015 Dec 3	doi: 10.1038/ncomms10127.
27040163	serIC_PMID27040163_Hs_K562.1	K562	Thomas Conrad?	2016 Apr 4	doi: 10.1038/ncomms11212
27453046	RBDmap_PMID_27453046_Hs_HeLa	HeLa	Alfredo Castello	2016 Aug 18	doi: 10.1016/j.molcel.2016.06.029.?Epub 2016 Jul 21
29636419	CARIC_PMID29636419_Hs_CARIC		Rongbing Huang	2018 Apr 24	doi: 10.1073/pnas.1718406115
30352994	eRIC_PMID30352994_Jurkat_human	Jurkat	Joel I Perez-Perri?	2018 Oct 23	doi: 10.1038/s41467-018-06557-8

Showing 1 to 10 of 24 entries

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Pubmed ID	Title	Author	Time	Journal
No data available in table

Transcripts

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Name	Transcript ID	bp	Protein	Translation ID
RPS26-201	ENST00000356464	1272	115aa	ENSP00000348849
RPS26-202	ENST00000548590	1204	No protein	-
RPS26-203	ENST00000552361	623	115aa	ENSP00000450339
RPS26-204	ENST00000646449	1140	115aa	ENSP00000496643

Showing 1 to 4 of 4 entries

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Gene Model

Click here to download ENSG00000197728's gene model file

Phenotypes

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ensgID	Trait	pValue	Pubmed ID
31467	Erythrocyte Indices	2.8270000E-005	-
31621	Erythrocyte Count	7.7940000E-005	-
60679	Psoriasis	1E-7	25574825
64006	Diabetes Mellitus, Type 1	1E-11	17554300
70424	Hypothyroidism	8E-8	27182965
85873	Psoriasis	4E-8	25574825
92175	Cleft Lip	1E-9	28232668
92176	Cleft Palate	1E-9	28232668
95328	Polycystic Ovary Syndrome	2E-7	26416764
104998	Psoriasis	1E-6	20953189

Showing 1 to 10 of 10 entries

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GWAS

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ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID
ENSG00000197728	rs1131017	12	56042145	Inflammatory skin disease	25574825		EFO_0000676
ENSG00000197728	rs705705	12	56041720	Type 1 diabetes	25751624	1.25	EFO_0001359
ENSG00000197728	rs1131017	12	56042145	Cognitive performance	30038396	0.017	EFO_0008354
ENSG00000197728	rs1131017	12	56042145	Self-reported math ability (MTAG)	30038396	0.0162	EFO_0004875
ENSG00000197728	rs1131017	12	56042145	Cognitive performance (MTAG)	30038396	0.0229	EFO_0008354
ENSG00000197728	rs705704	12	56041628	Nonsyndromic cleft lip with cleft palate	28232668	1.22	HP_0000175\|EFO_0003959
ENSG00000197728	rs1131017	12	56042145	Menarche (age at onset)	30595370		EFO_0004703

Showing 1 to 7 of 7 entries

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Protein-Protein Interaction (PPI)

Click here to download ENSG00000197728's PPI file

Orthologs

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Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
ENSG00000197728	homo_sapiens	ENSP00000496643	99.1304	98.2609	nomascus_leucogenys	ENSNLEP00000036521	99.1304	98.2609
ENSG00000197728	homo_sapiens	ENSP00000496643	100	100	nomascus_leucogenys	ENSNLEP00000024307	100	100
ENSG00000197728	homo_sapiens	ENSP00000496643	100	100	pan_paniscus	ENSPPAP00000025785	100	100
ENSG00000197728	homo_sapiens	ENSP00000496643	100	100	pan_paniscus	ENSPPAP00000004161	100	100
ENSG00000197728	homo_sapiens	ENSP00000496643	100	100	pongo_abelii	ENSPPYP00000005287	100	100
ENSG00000197728	homo_sapiens	ENSP00000496643	99.1304	99.1304	pan_troglodytes	ENSPTRP00000075616	99.1304	99.1304
ENSG00000197728	homo_sapiens	ENSP00000496643	100	100	gorilla_gorilla	ENSGGOP00000011278	100	100
ENSG00000197728	homo_sapiens	ENSP00000496643	100	99.1304	ornithorhynchus_anatinus	ENSOANP00000051298	100	99.1304
ENSG00000197728	homo_sapiens	ENSP00000496643	96.5217	94.7826	notamacropus_eugenii	ENSMEUP00000014109	96.5217	94.7826
ENSG00000197728	homo_sapiens	ENSP00000496643	95.6522	94.7826	notamacropus_eugenii	ENSMEUP00000007602	94.8276	93.9655

Showing 1 to 10 of 165 entries

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Gene Ontology

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Go ID	Go term	No. evidence	Entries	Species	Category
GO:0022627	part_of cytosolic small ribosomal subunit	4	HDA,IBA,IDA,NAS	Homo_sapiens(9606)	Component
GO:0002181	involved_in cytoplasmic translation	3	IC,IDA,NAS	Homo_sapiens(9606)	Process
GO:0003735	enables structural constituent of ribosome	3	HDA,IBA,IDA	Homo_sapiens(9606)	Function
GO:0003729	enables mRNA binding	2	IBA,IDA	Homo_sapiens(9606)	Function
GO:0003723	enables RNA binding	1	HDA	Homo_sapiens(9606)	Function
GO:0005515	enables protein binding	1	IPI	Homo_sapiens(9606)	Function
GO:0005654	located_in nucleoplasm	1	TAS	Homo_sapiens(9606)	Component
GO:0005737	located_in cytoplasm	1	NAS	Homo_sapiens(9606)	Component
GO:0005829	located_in cytosol	1	TAS	Homo_sapiens(9606)	Component
GO:0006412	involved_in translation	1	IC	Homo_sapiens(9606)	Process

Showing 1 to 10 of 18 entries

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Welcome to

RBP World!

Functions and Diseases

Description

RNA binding domains (RBDs)

RNA binding proteomes (RBPomes)

Literatures on RNA binding capacity

Transcripts

Gene Model

Pathways

Phenotypes

GWAS

Protein-Protein Interaction (PPI)

Paralogs

Orthologs

Gene Ontology

Expression