Functions and Diseases

RBP Type Non-canonical_RBPs
Diseases N.A.
Drug N.A.
Main interacting RNAs N.A.
Moonlighting functions Metabolic enzyme
Localizations N.A.
BulkPerturb-seq

Description

Ensembl ID ENSG00000197448 Gene ID 373156 Accession 16906
Symbol GSTK1 Alias GST;GST13;hGSTK1;GSTK1-1;GST13-13;GST13-13 Full Name glutathione S-transferase kappa 1
Status Confidence Length 26662 bases Strand Plus strand
Position 7 : 143244093 - 143270754 RNA binding domain N.A.
Summary This gene encodes a member of the kappa class of the glutathione transferase superfamily of enzymes that function in cellular detoxification. The encoded protein is localized to the peroxisome and catalyzes the conjugation of glutathione to a wide range of hydrophobic substates facilitating the removal of these compounds from cells. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Jan 2009]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal

Transcripts

Name Transcript ID bp Protein Translation ID
GSTK1-203 ENST00000436038 556 118aa ENSP00000408341
GSTK1-202 ENST00000409500 888 214aa ENSP00000386944
GSTK1-205 ENST00000443571 850 183aa ENSP00000415813
GSTK1-201 ENST00000358406 1032 226aa ENSP00000351181
GSTK1-204 ENST00000442394 2219 190aa ENSP00000406802
GSTK1-207 ENST00000479303 1185 282aa ENSP00000431049
GSTK1-209 ENST00000494735 832 No protein -
GSTK1-206 ENST00000473649 2692 No protein -
GSTK1-208 ENST00000489654 875 No protein -

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0004364enables glutathione transferase activity2IBA,IDAHomo_sapiens(9606)Function
GO:0004602enables glutathione peroxidase activity2IBA,IDAHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005739is_active_in mitochondrion1IBAHomo_sapiens(9606)Component
GO:0005759located_in mitochondrial matrix1TASHomo_sapiens(9606)Component
GO:0005777is_active_in peroxisome2IBA,IDAHomo_sapiens(9606)Component
GO:0005782located_in peroxisomal matrix1TASHomo_sapiens(9606)Component
GO:0005829located_in cytosol1TASHomo_sapiens(9606)Component
GO:0006749involved_in glutathione metabolic process1IBAHomo_sapiens(9606)Process
GO:0016020located_in membrane1HDAHomo_sapiens(9606)Component
GO:0030855involved_in epithelial cell differentiation1IEPHomo_sapiens(9606)Process
GO:0070062located_in extracellular exosome1HDAHomo_sapiens(9606)Component
GO:0098869involved_in cellular oxidant detoxification1IEAHomo_sapiens(9606)Process

Expression