Functions and Diseases

RBP Type Canonical_RBPs
Diseases Cancer
Drug N.A.
Main interacting RNAs N.A.
Moonlighting functions TF
Localizations NucleoliNucleoli rim
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000197385 Gene ID 344787 Accession 34513
Symbol ZNF860 Alias NA Full Name zinc finger protein 860
Status Confidence Length 9974 bases Strand Plus strand
Position 3 : 31981750 - 31991723 RNA binding domain zf-met
Summary Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000373274 zf-met PF12874 1.1e-06 1

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal

Transcripts

Name Transcript ID bp Protein Translation ID
ZNF860-201 ENST00000360311 3217 632aa ENSP00000373274
ZNF860-202 ENST00000489408 560 No protein -

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID
85241Schizophrenia8E-626198764

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000197385homo_sapiensENSP0000045921676.949266.7797homo_sapiensENSP0000037327471.835462.3418
ENSG00000197385homo_sapiensENSP0000050627375.19565.5226homo_sapiensENSP0000037327476.265866.4557
ENSG00000197385homo_sapiensENSP0000040326669.27859.447homo_sapiensENSP0000037327471.360861.2342
ENSG00000197385homo_sapiensENSP0000037566276.559168.172homo_sapiensENSP0000037327456.329150.1582
ENSG00000197385homo_sapiensENSP0000037968978.202767.4952homo_sapiensENSP0000037327464.715255.8544
ENSG00000197385homo_sapiensENSP0000049156764.345456.4067homo_sapiensENSP0000037327473.101364.0823
ENSG00000197385homo_sapiensENSP0000047038179.501969.3487homo_sapiensENSP0000037327465.664657.2785
ENSG00000197385homo_sapiensENSP0000037968481.037371.3128homo_sapiensENSP0000037327479.113969.6203
ENSG00000197385homo_sapiensENSP0000041769678.079369.5198homo_sapiensENSP0000037327459.177252.6899
ENSG00000197385homo_sapiensENSP0000050766663.002754.8257homo_sapiensENSP0000037327474.367164.7152
ENSG00000197385homo_sapiensENSP0000040965263.461551.7094homo_sapiensENSP0000037327446.993738.2911

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000197385homo_sapiensENSP0000037327494.620393.5127pan_paniscusENSPPAP0000002044697.235896.0976
ENSG00000197385homo_sapiensENSP0000037327497.626696.519pan_troglodytesENSPTRP0000001960497.626696.519
ENSG00000197385homo_sapiensENSP0000037327411.86719.17722panthera_leoENSPLOP0000002259371.428655.2381
ENSG00000197385homo_sapiensENSP0000037327410.60138.70253oryctolagus_cuniculusENSOCUP0000002666863.207551.8868
ENSG00000197385homo_sapiensENSP0000037327411.23428.38608canis_lupus_familiarisENSCAFP0084500652668.93251.4563
ENSG00000197385homo_sapiensENSP0000037327411.39249.17722felis_catusENSFCAP0000004160667.924554.717
ENSG00000197385homo_sapiensENSP0000037327412.816510.1266microcebus_murinusENSMICP0000004180876.415160.3774
ENSG00000197385homo_sapiensENSP0000037327410.75958.06962phocoena_sinusENSPSNP0000001825064.150948.1132
ENSG00000197385homo_sapiensENSP0000037327412.974710.6013prolemur_simusENSPSMP0000003542877.358563.2075
ENSG00000197385homo_sapiensENSP0000037327411.55068.38608bos_mutusENSBMUP0000000442153.676538.9706
ENSG00000197385homo_sapiensENSP0000037327457.278543.5127bos_mutusENSBMUP0000001902359.053844.8613
ENSG00000197385homo_sapiensENSP0000037327411.39248.70253neovison_visonENSNVIP0000003032568.571452.381
ENSG00000197385homo_sapiensENSP0000037327410.4438.38608sciurus_vulgarisENSSVLP0000502702864.077751.4563
ENSG00000197385homo_sapiensENSP0000037327457.594943.6709cervus_hanglu_yarkandensisENSCHYP0000001871559.090944.8052
ENSG00000197385homo_sapiensENSP0000037327457.120343.6709catagonus_wagneriENSCWAP0000000574758.699244.878
ENSG00000197385homo_sapiensENSP0000037327452.215242.2468propithecus_coquereliENSPCOP0000001964070.362556.9296
ENSG00000197385homo_sapiensENSP0000037327412.658210.2848propithecus_coquereliENSPCOP0000002662475.471761.3208

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0000978enables RNA polymerase II cis-regulatory region sequence-specific DNA binding1IBAHomo_sapiens(9606)Function
GO:0000981enables DNA-binding transcription factor activity, RNA polymerase II-specific1IBAHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005634is_active_in nucleus1IBAHomo_sapiens(9606)Component
GO:0006357involved_in regulation of transcription by RNA polymerase II1IBAHomo_sapiens(9606)Process
GO:0046872enables metal ion binding1IEAHomo_sapiens(9606)Function

Expression