Functions and Diseases

RBP Type Non-canonical_RBPs
Diseases Cancer Disease
Drug Drug
Main interacting RNAs N.A.
Moonlighting functions Transmemebrane
Localizations Stress granucle
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000196591 Gene ID 3066 Accession 4853
Symbol HDAC2 Alias HD2;RPD3;YAF1;KDAC2 Full Name histone deacetylase 2
Status Confidence Length 78281 bases Strand Minus strand
Position 6 : 113933028 - 114011308 RNA binding domain N.A.
Summary This gene product belongs to the histone deacetylase family. Histone deacetylases act via the formation of large multiprotein complexes, and are responsible for the deacetylation of lysine residues at the N-terminal regions of core histones (H2A, H2B, H3 and H4). This protein forms transcriptional repressor complexes by associating with many different proteins, including YY1, a mammalian zinc-finger transcription factor. Thus, it plays an important role in transcriptional regulation, cell cycle progression and developmental events. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2010]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal
23861535 Emerging complexity of the HuD/ELAVl4 gene; implications for neuronal development, function, and dysfunction. M Lucas Bronicki 2013-08-01 RNA (New York, N.Y.)
30542120 Fstl1/DIP2A/MGMT signaling pathway plays important roles in temozolomide resistance in glioblastoma. Er Nie 2019-04-01 Oncogene
23698401 Epigenetic control of cytomegalovirus latency and reactivation. Xue-feng Liu 2013-05-23 Viruses
30142192 Deacetylase activity-independent transcriptional activation by HDAC2 during TPA-induced HL-60 cell differentiation. Hyeonsoo Jung 2018-01-01 PloS one
33325150 HDAC2 promotes the EMT of colorectal cancer cells and via the modular scaffold function of ENSG00000274093.1. Zhi-Peng Qi 2021-01-01 Journal of cellular and molecular medicine

Transcripts

Name Transcript ID bp Protein Translation ID
HDAC2-205 ENST00000519065 9737 488aa ENSP00000430432
HDAC2-215 ENST00000523334 4810 No protein -
HDAC2-206 ENST00000519108 2000 458aa ENSP00000430008
HDAC2-201 ENST00000368632 2084 458aa ENSP00000357621
HDAC2-208 ENST00000520746 497 No protein -
HDAC2-204 ENST00000518756 826 No protein -
HDAC2-202 ENST00000425835 553 161aa ENSP00000417026
HDAC2-216 ENST00000523628 549 103aa ENSP00000427861
HDAC2-212 ENST00000521610 580 100aa ENSP00000429901
HDAC2-213 ENST00000522371 502 86aa ENSP00000428599
HDAC2-210 ENST00000521163 557 109aa ENSP00000428024
HDAC2-203 ENST00000518690 564 71aa ENSP00000428653
HDAC2-214 ENST00000523240 557 65aa ENSP00000429236
HDAC2-211 ENST00000521233 733 No protein -
HDAC2-209 ENST00000520895 551 60aa ENSP00000428861
HDAC2-217 ENST00000524334 570 52aa ENSP00000428989
HDAC2-207 ENST00000520170 690 No protein -

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID
56275Erythrocyte Count1.3300000E-005-

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000196591homo_sapiensENSP0000050916119.176811.5061homo_sapiensENSP0000043043242.008225.2049
ENSG00000196591homo_sapiensENSP0000050760617.914411.2299homo_sapiensENSP0000043043241.188525.8197
ENSG00000196591homo_sapiensENSP0000008005918.869811.3017homo_sapiensENSP0000043043238.319722.9508
ENSG00000196591homo_sapiensENSP0000036264994.605886.722homo_sapiensENSP0000043043293.442685.6557
ENSG00000196591homo_sapiensENSP0000021627114.49937.17489homo_sapiensENSP0000043043219.8779.83607
ENSG00000196591homo_sapiensENSP0000036267461.538540.8488homo_sapiensENSP0000043043247.54131.5574
ENSG00000196591homo_sapiensENSP0000029575734.293922.1902homo_sapiensENSP0000043043224.385215.7787
ENSG00000196591homo_sapiensENSP0000030296778.27159.1121homo_sapiensENSP0000043043268.647551.8443
ENSG00000196591homo_sapiensENSP0000033406114.3218.47737homo_sapiensENSP0000043043235.655721.1066
ENSG00000196591homo_sapiensENSP0000044048119.100111.6621homo_sapiensENSP0000043043242.62326.0246

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000196591homo_sapiensENSP0000043043297.950897.9508nomascus_leucogenysENSNLEP0000003837189.681189.6811
ENSG00000196591homo_sapiensENSP0000043043293.442691.8033pan_paniscusENSPPAP0000001997889.411887.8431
ENSG00000196591homo_sapiensENSP0000043043299.795199.7951pongo_abeliiENSPPYP0000001896483.965583.9655
ENSG00000196591homo_sapiensENSP00000430432100100pan_troglodytesENSPTRP0000004969683.993183.9931
ENSG00000196591homo_sapiensENSP00000430432100100gorilla_gorillaENSGGOP00000005320100100
ENSG00000196591homo_sapiensENSP0000043043299.590299.3852ornithorhynchus_anatinusENSOANP0000000576099.590299.3852
ENSG00000196591homo_sapiensENSP0000043043299.795199.5902sarcophilus_harrisiiENSSHAP0000003830499.795199.5902
ENSG00000196591homo_sapiensENSP0000043043264.549264.3443notamacropus_eugeniiENSMEUP0000001349472.748372.5173
ENSG00000196591homo_sapiensENSP0000043043281.557481.5574choloepus_hoffmanniENSCHOP0000001165968.384968.3849
ENSG00000196591homo_sapiensENSP0000043043299.590299.3852dasypus_novemcinctusENSDNOP0000003114484.08383.91
ENSG00000196591homo_sapiensENSP0000043043295.901695.9016erinaceus_europaeusENSEEUP0000000546599.574599.5745
ENSG00000196591homo_sapiensENSP0000043043271.311563.9344echinops_telfairiENSETEP0000000632478.911670.7483
ENSG00000196591homo_sapiensENSP0000043043299.180398.9754echinops_telfairiENSETEP0000000688399.180398.9754
ENSG00000196591homo_sapiensENSP0000043043298.770598.3607callithrix_jacchusENSCJAP0000007475098.16797.7597
ENSG00000196591homo_sapiensENSP0000043043299.795199.7951cercocebus_atysENSCATP0000004005999.795199.7951
ENSG00000196591homo_sapiensENSP0000043043299.795199.7951macaca_fascicularisENSMFAP0000000008399.795199.7951
ENSG00000196591homo_sapiensENSP0000043043299.795199.7951macaca_mulattaENSMMUP0000005772499.795199.7951
ENSG00000196591homo_sapiensENSP0000043043299.795199.7951macaca_nemestrinaENSMNEP0000000044999.795199.7951
ENSG00000196591homo_sapiensENSP0000043043299.795199.7951papio_anubisENSPANP0000005024699.795199.7951
ENSG00000196591homo_sapiensENSP0000043043299.795199.7951mandrillus_leucophaeusENSMLEP0000003298999.795199.7951
ENSG00000196591homo_sapiensENSP0000043043299.180399.1803tursiops_truncatusENSTTRP0000001426283.018983.0189
ENSG00000196591homo_sapiensENSP0000043043296.721396.1066vulpes_vulpesENSVVUP0000000911491.472990.8915
ENSG00000196591homo_sapiensENSP0000043043299.795199.7951mus_spretusMGP_SPRETEiJ_P002377299.795199.7951
ENSG00000196591homo_sapiensENSP0000043043294.672194.0574equus_asinusENSEASP0000501193292.771192.1687
ENSG00000196591homo_sapiensENSP0000043043299.590299.5902capra_hircusENSCHIP0000002892699.590299.5902
ENSG00000196591homo_sapiensENSP0000043043299.590298.9754loxodonta_africanaENSLAFP0000000467099.794799.1786
ENSG00000196591homo_sapiensENSP0000043043299.590299.3852panthera_leoENSPLOP0000000458799.590299.3852
ENSG00000196591homo_sapiensENSP0000043043299.590299.3852ailuropoda_melanoleucaENSAMEP0000001391999.590299.3852
ENSG00000196591homo_sapiensENSP0000043043299.385299.3852bos_indicus_hybridENSBIXP0000502982599.385299.3852
ENSG00000196591homo_sapiensENSP0000043043292.41890.5738oryctolagus_cuniculusENSOCUP0000004015177.624876.0757
ENSG00000196591homo_sapiensENSP0000043043299.795199.5902equus_caballusENSECAP0000001159198.383898.1818
ENSG00000196591homo_sapiensENSP0000043043299.590299.3852canis_lupus_familiarisENSCAFP0084502866899.590299.3852
ENSG00000196591homo_sapiensENSP0000043043299.590299.3852panthera_pardusENSPPRP0000000642399.590299.3852
ENSG00000196591homo_sapiensENSP0000043043295.901695.9016marmota_marmota_marmotaENSMMMP0000001719795.901695.9016
ENSG00000196591homo_sapiensENSP0000043043299.795199.7951balaenoptera_musculusENSBMSP0001001796299.795199.7951
ENSG00000196591homo_sapiensENSP0000043043243.647542.8279balaenoptera_musculusENSBMSP0001001461692.608790.8696
ENSG00000196591homo_sapiensENSP0000043043299.385299.3852cavia_porcellusENSCPOP0000001292099.385299.3852
ENSG00000196591homo_sapiensENSP0000043043296.106694.4672felis_catusENSFCAP0000003523777.90776.5781
ENSG00000196591homo_sapiensENSP0000043043289.95988.9344ursus_americanusENSUAMP0000000157898.430597.3094
ENSG00000196591homo_sapiensENSP0000043043299.590299.3852monodelphis_domesticaENSMODP0000002226499.590299.3852
ENSG00000196591homo_sapiensENSP0000043043295.696795.6967bison_bison_bisonENSBBBP0000001872395.696795.6967
ENSG00000196591homo_sapiensENSP0000043043299.795199.7951monodon_monocerosENSMMNP0001500710599.795199.7951
ENSG00000196591homo_sapiensENSP0000043043295.08293.4426monodon_monocerosENSMMNP0001500433691.159189.5874
ENSG00000196591homo_sapiensENSP0000043043299.590299.5902sus_scrofaENSSSCP0000000478199.590299.5902
ENSG00000196591homo_sapiensENSP0000043043293.032890.9836microcebus_murinusENSMICP0000000023883.150281.3187
ENSG00000196591homo_sapiensENSP0000043043284.016481.3525octodon_degusENSODEP0000001730393.181890.2273
ENSG00000196591homo_sapiensENSP0000043043299.795199.5902octodon_degusENSODEP0000000103799.795199.5902
ENSG00000196591homo_sapiensENSP0000043043278.893476.4344octodon_degusENSODEP0000001760090.801987.9717
ENSG00000196591homo_sapiensENSP0000043043299.795199.7951jaculus_jaculusENSJJAP0000000316999.795199.7951
ENSG00000196591homo_sapiensENSP0000043043299.590299.5902ovis_aries_rambouilletENSOARP0002000629795.669395.6693
ENSG00000196591homo_sapiensENSP0000043043293.442693.2377ursus_maritimusENSUMAP0000003541799.563399.345
ENSG00000196591homo_sapiensENSP0000043043281.352580.3279ochotona_princepsENSOPRP0000000278372.710671.7949
ENSG00000196591homo_sapiensENSP0000043043286.885285.6557delphinapterus_leucasENSDLEP0000001205395.280993.9326
ENSG00000196591homo_sapiensENSP0000043043295.08293.2377delphinapterus_leucasENSDLEP0000001515095.670193.8144
ENSG00000196591homo_sapiensENSP0000043043299.795199.7951physeter_catodonENSPCTP0000502058499.795199.7951
ENSG00000196591homo_sapiensENSP0000043043299.590299.5902mus_caroliMGP_CAROLIEiJ_P002263199.590299.5902
ENSG00000196591homo_sapiensENSP0000043043299.590299.5902mus_musculusENSMUSP0000001991199.590299.5902
ENSG00000196591homo_sapiensENSP0000043043299.180398.9754dipodomys_ordiiENSDORP0000001252099.180398.9754
ENSG00000196591homo_sapiensENSP0000043043294.057493.8525mustela_putorius_furoENSMPUP0000001019397.867897.6546
ENSG00000196591homo_sapiensENSP0000043043290.983689.7541aotus_nancymaaeENSANAP0000003409095.483994.1936
ENSG00000196591homo_sapiensENSP0000043043257.58255.7377saimiri_boliviensis_boliviensisENSSBOP0000001904789.490486.6242
ENSG00000196591homo_sapiensENSP0000043043244.87744.2623saimiri_boliviensis_boliviensisENSSBOP0000003708796.902795.5752
ENSG00000196591homo_sapiensENSP0000043043286.680386.6803vicugna_pacosENSVPAP000000013949090
ENSG00000196591homo_sapiensENSP0000043043299.795199.7951chlorocebus_sabaeusENSCSAP0000001177299.795199.7951
ENSG00000196591homo_sapiensENSP0000043043279.098479.0984tupaia_belangeriENSTBEP0000001314282.127782.1277
ENSG00000196591homo_sapiensENSP0000043043299.795199.1803mesocricetus_auratusENSMAUP0000002318799.795199.1803
ENSG00000196591homo_sapiensENSP0000043043280.532879.0984phocoena_sinusENSPSNP0000000515994.927593.2367
ENSG00000196591homo_sapiensENSP0000043043299.795199.7951phocoena_sinusENSPSNP0000001147499.795199.7951
ENSG00000196591homo_sapiensENSP0000043043299.590299.5902camelus_dromedariusENSCDRP0000500452299.590299.5902
ENSG00000196591homo_sapiensENSP0000043043293.032892.6229carlito_syrichtaENSTSYP0000000858899.126698.69
ENSG00000196591homo_sapiensENSP0000043043293.442693.2377panthera_tigris_altaicaENSPTIP0000001973899.563399.345
ENSG00000196591homo_sapiensENSP0000043043299.590298.9754rattus_norvegicusENSRNOP0000000074299.590298.9754
ENSG00000196591homo_sapiensENSP0000043043296.311594.8771prolemur_simusENSPSMP0000003655483.481382.238
ENSG00000196591homo_sapiensENSP0000043043256.967255.9426microtus_ochrogasterENSMOCP0000000729895.205593.4931
ENSG00000196591homo_sapiensENSP0000043043257.58257.582microtus_ochrogasterENSMOCP00000008026100100
ENSG00000196591homo_sapiensENSP0000043043277.45977.2541sorex_araneusENSSARP0000000031687.90787.6744
ENSG00000196591homo_sapiensENSP0000043043299.795199.5902peromyscus_maniculatus_bairdiiENSPEMP0000002182699.795199.5902
ENSG00000196591homo_sapiensENSP0000043043299.385299.1803bos_mutusENSBMUP0000000721199.385299.1803
ENSG00000196591homo_sapiensENSP0000043043299.795199.7951mus_spicilegusENSMSIP0000000513199.795199.7951
ENSG00000196591homo_sapiensENSP0000043043298.155797.541cricetulus_griseus_chok1gshdENSCGRP0000101622299.377698.7552
ENSG00000196591homo_sapiensENSP0000043043278.893478.8934pteropus_vampyrusENSPVAP0000000574266.265166.2651
ENSG00000196591homo_sapiensENSP0000043043298.565696.5164myotis_lucifugusENSMLUP0000001943398.565696.5164
ENSG00000196591homo_sapiensENSP0000043043299.590299.5902myotis_lucifugusENSMLUP0000000283594.921994.9219
ENSG00000196591homo_sapiensENSP0000043043299.590299.3852vombatus_ursinusENSVURP0001002997399.590299.3852
ENSG00000196591homo_sapiensENSP0000043043299.385299.3852rhinolophus_ferrumequinumENSRFEP0001002556499.589399.5893
ENSG00000196591homo_sapiensENSP0000043043299.590299.3852neovison_visonENSNVIP0000000803099.590299.3852
ENSG00000196591homo_sapiensENSP0000043043299.385299.3852bos_taurusENSBTAP0000005960699.385299.3852
ENSG00000196591homo_sapiensENSP0000043043224.590222.7459heterocephalus_glaber_femaleENSHGLP0000000412982.191876.0274
ENSG00000196591homo_sapiensENSP0000043043224.590222.9508heterocephalus_glaber_femaleENSHGLP0000000937276.923171.7949
ENSG00000196591homo_sapiensENSP0000043043256.147555.3279heterocephalus_glaber_femaleENSHGLP0000005040695.138993.75
ENSG00000196591homo_sapiensENSP0000043043299.795199.7951rhinopithecus_bietiENSRBIP0000002415299.795199.7951
ENSG00000196591homo_sapiensENSP0000043043293.852593.8525canis_lupus_dingoENSCAFP0002002506595.615995.6159
ENSG00000196591homo_sapiensENSP0000043043299.590299.3852sciurus_vulgarisENSSVLP0000501279799.590299.3852
ENSG00000196591homo_sapiensENSP0000043043299.590299.3852phascolarctos_cinereusENSPCIP0000003495899.590299.3852
ENSG00000196591homo_sapiensENSP0000043043281.352581.1475procavia_capensisENSPCAP0000000799968.330568.1583
ENSG00000196591homo_sapiensENSP0000043043299.795199.7951nannospalax_galiliENSNGAP0000002161999.795199.7951
ENSG00000196591homo_sapiensENSP0000043043299.385299.1803bos_grunniensENSBGRP0000002166199.385299.1803
ENSG00000196591homo_sapiensENSP0000043043295.286995.2869chinchilla_lanigeraENSCLAP0000000096698.936298.9362
ENSG00000196591homo_sapiensENSP0000043043242.213141.3934cervus_hanglu_yarkandensisENSCHYP0000003836191.555689.7778
ENSG00000196591homo_sapiensENSP0000043043242.213141.3934cervus_hanglu_yarkandensisENSCHYP0000002350691.555689.7778
ENSG00000196591homo_sapiensENSP0000043043299.590299.5902cervus_hanglu_yarkandensisENSCHYP0000003553699.590299.5902
ENSG00000196591homo_sapiensENSP0000043043299.590299.5902catagonus_wagneriENSCWAP0000001106699.590299.5902
ENSG00000196591homo_sapiensENSP0000043043299.590299.5902ictidomys_tridecemlineatusENSSTOP0000001145799.590299.5902
ENSG00000196591homo_sapiensENSP0000043043286.065686.0656otolemur_garnettiiENSOGAP0000000986399.526199.5261
ENSG00000196591homo_sapiensENSP0000043043299.795199.5902cebus_imitatorENSCCAP0000003563299.795199.5902
ENSG00000196591homo_sapiensENSP0000043043299.590299.5902urocitellus_parryiiENSUPAP0001002941399.590299.5902
ENSG00000196591homo_sapiensENSP0000043043256.352555.3279moschus_moschiferusENSMMSP0000001787179.941978.4884
ENSG00000196591homo_sapiensENSP0000043043299.385299.3852moschus_moschiferusENSMMSP0000000644199.385299.3852
ENSG00000196591homo_sapiensENSP0000043043294.467294.2623moschus_moschiferusENSMMSP0000000038098.92798.7124
ENSG00000196591homo_sapiensENSP0000043043298.770598.5656moschus_moschiferusENSMMSP0000000319998.770598.5656
ENSG00000196591homo_sapiensENSP0000043043299.795199.7951rhinopithecus_roxellanaENSRROP0000001776799.795199.7951
ENSG00000196591homo_sapiensENSP0000043043299.590299.5902mus_pahariMGP_PahariEiJ_P008581499.590299.5902
ENSG00000196591homo_sapiensENSP000004304329.426234.71311caenorhabditis_elegansF43G6.17a.116.37018.18505
ENSG00000196591homo_sapiensENSP0000043043214.75418.81148caenorhabditis_elegansF43G6.4.126.666715.9259
ENSG00000196591homo_sapiensENSP0000043043211.68036.35246caenorhabditis_elegansF43G6.11.111.22056.10236
ENSG00000196591homo_sapiensENSP0000043043286.680376.6393drosophila_melanogasterFBpp007317381.1971.785
ENSG00000196591homo_sapiensENSP0000043043277.45972.1311ciona_intestinalisENSCINP0000000541093.564487.1287
ENSG00000196591homo_sapiensENSP0000043043293.442687.2951eptatretus_burgeriENSEBUP0000001154391.382885.3707
ENSG00000196591homo_sapiensENSP0000043043293.852589.1393callorhinchus_miliiENSCMIP0000001091689.980485.4617
ENSG00000196591homo_sapiensENSP0000043043295.08287.9098lepisosteus_oculatusENSLOCP0000002098594.693987.551
ENSG00000196591homo_sapiensENSP0000043043273.360767.418clupea_harengusENSCHAP0000003938289.949782.6633
ENSG00000196591homo_sapiensENSP0000043043296.106688.5246astyanax_mexicanusENSAMXP0000001473996.106688.5246
ENSG00000196591homo_sapiensENSP0000043043295.286987.9098ictalurus_punctatusENSIPUP0000000222685.477978.8603
ENSG00000196591homo_sapiensENSP0000043043292.213186.8852esox_luciusENSELUP0000005822285.551380.6084
ENSG00000196591homo_sapiensENSP0000043043293.032886.6803electrophorus_electricusENSEEEP0000001378089.019682.9412
ENSG00000196591homo_sapiensENSP0000043043290.983684.6311oncorhynchus_kisutchENSOKIP0000502953891.35884.9794
ENSG00000196591homo_sapiensENSP0000043043291.188584.0164oncorhynchus_mykissENSOMYP0000013545491.752684.5361
ENSG00000196591homo_sapiensENSP0000043043288.524682.7869salmo_salarENSSSAP0000005815790.187984.3424
ENSG00000196591homo_sapiensENSP0000043043291.598485.4508salmo_truttaENSSTUP0000009126293.12586.875
ENSG00000196591homo_sapiensENSP0000043043295.08287.9098fundulus_heteroclitusENSFHEP0000001643094.693987.551
ENSG00000196591homo_sapiensENSP0000043043289.139381.7623poecilia_reticulataENSPREP0000003099894.978287.1179
ENSG00000196591homo_sapiensENSP0000043043295.491887.7049xiphophorus_maculatusENSXMAP0000001903895.10287.3469
ENSG00000196591homo_sapiensENSP0000043043295.286988.7295oryzias_latipesENSORLP0000002252995.09288.5481
ENSG00000196591homo_sapiensENSP0000043043295.901688.5246oreochromis_niloticusENSONIP0000001428595.510288.1633
ENSG00000196591homo_sapiensENSP0000043043284.836178.4836haplochromis_burtoniENSHBUP0000003448790.789583.9912
ENSG00000196591homo_sapiensENSP0000043043295.696788.3197astatotilapia_callipteraENSACLP0000002843995.50188.1391
ENSG00000196591homo_sapiensENSP0000043043255.12347.9508sparus_aurataENSSAUP0001001102375.561865.7303
ENSG00000196591homo_sapiensENSP0000043043292.827986.6803lates_calcariferENSLCAP0001004897689.349183.432
ENSG00000196591homo_sapiensENSP0000043043298.565697.541xenopus_tropicalisENSXETP0000001597898.565697.541
ENSG00000196591homo_sapiensENSP0000043043299.590299.3852chrysemys_picta_belliiENSCPBP0000002220374.654474.5008
ENSG00000196591homo_sapiensENSP0000043043294.057493.4426sphenodon_punctatusENSSPUP0000000027296.428695.7983
ENSG00000196591homo_sapiensENSP0000043043298.565697.7459crocodylus_porosusENSCPRP0000500461388.419187.6838
ENSG00000196591homo_sapiensENSP0000043043298.975498.5656laticauda_laticaudataENSLLTP0000000256098.975498.5656
ENSG00000196591homo_sapiensENSP0000043043297.131196.7213notechis_scutatusENSNSUP0000002581398.956298.5386
ENSG00000196591homo_sapiensENSP0000043043298.975498.5656pseudonaja_textilisENSPTXP0000002026398.975498.5656
ENSG00000196591homo_sapiensENSP0000043043293.442693.4426anas_platyrhynchos_platyrhynchosENSAPLP0000000660599.563399.5633
ENSG00000196591homo_sapiensENSP0000043043296.926295.9016gallus_gallusENSGALP0001001902689.245388.3019
ENSG00000196591homo_sapiensENSP0000043043293.237793.2377meleagris_gallopavoENSMGAP0000001415799.34599.345
ENSG00000196591homo_sapiensENSP0000043043293.237792.8279serinus_canariaENSSCAP0000002074899.34598.9083
ENSG00000196591homo_sapiensENSP0000043043299.385298.9754parus_majorENSPMJP0000001889299.385298.9754
ENSG00000196591homo_sapiensENSP0000043043299.180398.3607anolis_carolinensisENSACAP0000001204699.180398.3607
ENSG00000196591homo_sapiensENSP0000043043291.598483.6066neolamprologus_brichardiENSNBRP0000001479892.164984.1237
ENSG00000196591homo_sapiensENSP0000043043298.975498.3607naja_najaENSNNAP0000000039198.975498.3607
ENSG00000196591homo_sapiensENSP0000043043295.286994.6721podarcis_muralisENSPMRP0000000891994.512293.9024
ENSG00000196591homo_sapiensENSP0000043043293.237792.8279geospiza_fortisENSGFOP0000001083599.34598.9083
ENSG00000196591homo_sapiensENSP0000043043299.385298.9754taeniopygia_guttataENSTGUP0000002753699.385298.9754
ENSG00000196591homo_sapiensENSP0000043043295.491889.959erpetoichthys_calabaricusENSECRP0000000682095.296589.7751
ENSG00000196591homo_sapiensENSP0000043043294.057493.6475salvator_merianaeENSSMRP0000001626399.350698.9177
ENSG00000196591homo_sapiensENSP0000043043295.901688.9344oryzias_javanicusENSOJAP0000004323895.705588.7526
ENSG00000196591homo_sapiensENSP0000043043288.319781.1475amphilophus_citrinellusENSACIP0000000920490.356483.0189
ENSG00000196591homo_sapiensENSP0000043043291.803385.2459dicentrarchus_labraxENSDLAP0000502154491.615585.0716
ENSG00000196591homo_sapiensENSP0000043043295.901688.9344amphiprion_perculaENSAPEP0000000403895.510288.5714
ENSG00000196591homo_sapiensENSP0000043043279.098471.7213oryzias_sinensisENSOSIP0000003782892.124183.5322
ENSG00000196591homo_sapiensENSP0000043043293.237793.2377pelodiscus_sinensisENSPSIP0000000473799.34599.345
ENSG00000196591homo_sapiensENSP0000043043299.590299.3852gopherus_evgoodeiENSGEVP0000501990499.590299.3852
ENSG00000196591homo_sapiensENSP0000043043296.106694.6721chelonoidis_abingdoniiENSCABP0000001165697.505296.0499
ENSG00000196591homo_sapiensENSP0000043043296.106689.1393seriola_dumeriliENSSDUP0000001313095.9188.9571
ENSG00000196591homo_sapiensENSP0000043043245.08234.4262cottoperca_gobioENSCGOP0000003108352.757840.2878
ENSG00000196591homo_sapiensENSP0000043043296.106695.9016struthio_camelus_australisENSSCUP0000002372498.945198.7342
ENSG00000196591homo_sapiensENSP0000043043299.590299.1803anser_brachyrhynchusENSABRP0000000048099.590299.1803
ENSG00000196591homo_sapiensENSP0000043043295.491887.2951cynoglossus_semilaevisENSCSEP0000002658095.491887.2951
ENSG00000196591homo_sapiensENSP0000043043295.491887.5poecilia_formosaENSPFOP0000001560094.908386.9654
ENSG00000196591homo_sapiensENSP0000043043295.901689.5492myripristis_murdjanENSMMDP0000503717095.510289.1837
ENSG00000196591homo_sapiensENSP0000043043299.385299.1803strigops_habroptilaENSSHBP0000500443989.814889.6296
ENSG00000196591homo_sapiensENSP0000043043295.901689.1393amphiprion_ocellarisENSAOCP0000000490595.510288.7755
ENSG00000196591homo_sapiensENSP0000043043299.590299.1803terrapene_carolina_triunguisENSTMTP0000003091899.590299.1803
ENSG00000196591homo_sapiensENSP0000043043218.237717.623hucho_huchoENSHHUP0000004917991.752688.6598
ENSG00000196591homo_sapiensENSP0000043043229.713126.2295hucho_huchoENSHHUP0000004917764.159356.6372
ENSG00000196591homo_sapiensENSP0000043043295.491888.5246betta_splendensENSBSLP0000001158294.908387.9837
ENSG00000196591homo_sapiensENSP0000043043295.491888.7295pygocentrus_nattereriENSPNAP0000001364795.491888.7295
ENSG00000196591homo_sapiensENSP0000043043288.934481.7623anabas_testudineusENSATEP0000005042087.854280.7692
ENSG00000196591homo_sapiensENSP0000043043283.196776.0246ciona_savignyiENSCSAVP0000001821690.022282.2616
ENSG00000196591homo_sapiensENSP0000043043291.803386.0656seriola_lalandi_dorsalisENSSLDP0000001692195.726589.7436
ENSG00000196591homo_sapiensENSP0000043043295.491888.5246labrus_bergyltaENSLBEP0000001400295.296588.3436
ENSG00000196591homo_sapiensENSP0000043043243.442641.5984pundamilia_nyerereiENSPNYP0000001515396.803692.6941
ENSG00000196591homo_sapiensENSP0000043043296.311589.1393mastacembelus_armatusENSMAMP0000005447596.114588.9571
ENSG00000196591homo_sapiensENSP0000043043295.491888.3197stegastes_partitusENSSPAP0000000689995.10287.9592
ENSG00000196591homo_sapiensENSP0000043043290.983684.6311oncorhynchus_tshawytschaENSOTSP0000506594291.735585.3306
ENSG00000196591homo_sapiensENSP0000043043284.221378.2787acanthochromis_polyacanthusENSAPOP0000003168592.152585.6502
ENSG00000196591homo_sapiensENSP0000043043299.385299.1803aquila_chrysaetos_chrysaetosENSACCP0002000946299.385299.1803
ENSG00000196591homo_sapiensENSP0000043043295.696787.9098cyprinodon_variegatusENSCVAP0000002192895.306187.551
ENSG00000196591homo_sapiensENSP0000043043292.41886.4754denticeps_clupeoidesENSDCDP0000003003592.41886.4754
ENSG00000196591homo_sapiensENSP0000043043295.901688.9344larimichthys_croceaENSLCRP0000501419895.705588.7526
ENSG00000196591homo_sapiensENSP0000043043294.672187.5takifugu_rubripesENSTRUP0000006865794.478587.3211
ENSG00000196591homo_sapiensENSP0000043043299.385298.9754ficedula_albicollisENSFALP0000001145399.385298.9754
ENSG00000196591homo_sapiensENSP0000043043296.926296.5164coturnix_japonicaENSCJPP0000501063297.727397.314
ENSG00000196591homo_sapiensENSP0000043043295.286987.2951poecilia_latipinnaENSPLAP0000001515694.704786.7617
ENSG00000196591homo_sapiensENSP0000043043295.696788.3197maylandia_zebraENSMZEP0000502111695.50188.1391
ENSG00000196591homo_sapiensENSP0000043043294.262387.0902tetraodon_nigroviridisENSTNIP0000000783793.877586.7347
ENSG00000196591homo_sapiensENSP0000043043293.442687.0902paramormyrops_kingsleyaeENSPKIP0000000029091.750585.5131
ENSG00000196591homo_sapiensENSP0000043043296.106689.3443scleropages_formosusENSSFOP0001503319595.9189.1616
ENSG00000196591homo_sapiensENSP0000043043295.286993.4426leptobrachium_leishanenseENSLLEP0000002658383.783882.1622
ENSG00000196591homo_sapiensENSP0000043043295.696788.9344oryzias_melastigmaENSOMEP0000000254595.50188.7526

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0000118part_of histone deacetylase complex1IDAHomo_sapiens(9606)Component
GO:0000122involved_in negative regulation of transcription by RNA polymerase II3IBA,IMP,NASHomo_sapiens(9606)Process
GO:0000781located_in chromosome, telomeric region1IDAHomo_sapiens(9606)Component
GO:0000785part_of chromatin1HDAHomo_sapiens(9606)Component
GO:0001975involved_in response to amphetamine1IEAHomo_sapiens(9606)Process
GO:0003300involved_in cardiac muscle hypertrophy1IEAHomo_sapiens(9606)Process
GO:0003682enables chromatin binding1ISSHomo_sapiens(9606)Function
GO:0003723enables RNA binding1HDAHomo_sapiens(9606)Function
GO:0004407enables histone deacetylase activity3IBA,IDA,ISSHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005634is_active_in nucleus3IBA,IDA,NASHomo_sapiens(9606)Component
GO:0005654located_in nucleoplasm2IDA,TASHomo_sapiens(9606)Component
GO:0005737located_in cytoplasm2IDA,TASHomo_sapiens(9606)Component
GO:0006338involved_in chromatin remodeling3HDA,IC,IDAHomo_sapiens(9606)Process
GO:0008284involved_in positive regulation of cell population proliferation1IMPHomo_sapiens(9606)Process
GO:0009410involved_in response to xenobiotic stimulus1IEAHomo_sapiens(9606)Process
GO:0009913involved_in epidermal cell differentiation1ISSHomo_sapiens(9606)Process
GO:0010718involved_in positive regulation of epithelial to mesenchymal transition1IEAHomo_sapiens(9606)Process
GO:0010977involved_in negative regulation of neuron projection development1ISSHomo_sapiens(9606)Process
GO:0016358involved_in dendrite development1ISSHomo_sapiens(9606)Process
GO:0016575involved_in histone deacetylation3IBA,IDA,IMPHomo_sapiens(9606)Process
GO:0016580part_of Sin3 complex2IDA,NASHomo_sapiens(9606)Component
GO:0016581part_of NuRD complex3IBA,IDA,NASHomo_sapiens(9606)Component
GO:0019899enables enzyme binding1IPIHomo_sapiens(9606)Function
GO:0030336involved_in negative regulation of cell migration1NASHomo_sapiens(9606)Process
GO:0030512involved_in negative regulation of transforming growth factor beta receptor signaling pathway1NASHomo_sapiens(9606)Process
GO:0031000involved_in response to caffeine1IEAHomo_sapiens(9606)Process
GO:0031072enables heat shock protein binding1IEAHomo_sapiens(9606)Function
GO:0031492contributes_to nucleosomal DNA binding1HDAHomo_sapiens(9606)Function
GO:0032496involved_in response to lipopolysaccharide1IEAHomo_sapiens(9606)Process
GO:0032732involved_in positive regulation of interleukin-1 production1IEAHomo_sapiens(9606)Process
GO:0032760involved_in positive regulation of tumor necrosis factor production1IEAHomo_sapiens(9606)Process
GO:0032922involved_in circadian regulation of gene expression1ISSHomo_sapiens(9606)Process
GO:0032967involved_in positive regulation of collagen biosynthetic process1ICHomo_sapiens(9606)Process
GO:0032991part_of protein-containing complex2HDA,IDAHomo_sapiens(9606)Component
GO:0033558enables protein lysine deacetylase activity2IMP,TASHomo_sapiens(9606)Function
GO:0034605involved_in cellular response to heat1IEAHomo_sapiens(9606)Process
GO:0035094involved_in response to nicotine1IEAHomo_sapiens(9606)Process
GO:0035098part_of ESC/E(Z) complex1IDAHomo_sapiens(9606)Component
GO:0042220involved_in response to cocaine1IEAHomo_sapiens(9606)Process
GO:0042475involved_in odontogenesis of dentin-containing tooth1ISSHomo_sapiens(9606)Process
GO:0042531involved_in positive regulation of tyrosine phosphorylation of STAT protein1IEAHomo_sapiens(9606)Process
GO:0042659involved_in regulation of cell fate specification1NASHomo_sapiens(9606)Process
GO:0042733involved_in embryonic digit morphogenesis1ISSHomo_sapiens(9606)Process
GO:0042826enables histone deacetylase binding1IPIHomo_sapiens(9606)Function
GO:0043066involved_in negative regulation of apoptotic process1ISSHomo_sapiens(9606)Process
GO:0043392involved_in negative regulation of DNA binding1IEAHomo_sapiens(9606)Process
GO:0043433involved_in negative regulation of DNA-binding transcription factor activity1IMPHomo_sapiens(9606)Process
GO:0043565enables sequence-specific DNA binding1IDAHomo_sapiens(9606)Function
GO:0045347involved_in negative regulation of MHC class II biosynthetic process1ICHomo_sapiens(9606)Process
GO:0045862involved_in positive regulation of proteolysis1IMPHomo_sapiens(9606)Process
GO:0045892involved_in negative regulation of DNA-templated transcription3IC,IMP,NASHomo_sapiens(9606)Process
GO:0045893involved_in positive regulation of DNA-templated transcription2IC,NASHomo_sapiens(9606)Process
GO:0045944involved_in positive regulation of transcription by RNA polymerase II1IMPHomo_sapiens(9606)Process
GO:0048149involved_in behavioral response to ethanol1IEAHomo_sapiens(9606)Process
GO:0048714involved_in positive regulation of oligodendrocyte differentiation1IEAHomo_sapiens(9606)Process
GO:0051059enables NF-kappaB binding1IPIHomo_sapiens(9606)Function
GO:0055093involved_in response to hyperoxia1IEAHomo_sapiens(9606)Process
GO:0060789involved_in hair follicle placode formation1ISSHomo_sapiens(9606)Process
GO:0061000involved_in negative regulation of dendritic spine development1IEAHomo_sapiens(9606)Process
GO:0061029involved_in eyelid development in camera-type eye1ISSHomo_sapiens(9606)Process
GO:0061198involved_in fungiform papilla formation1ISSHomo_sapiens(9606)Process
GO:0061629enables RNA polymerase II-specific DNA-binding transcription factor binding1IPIHomo_sapiens(9606)Function
GO:0070301involved_in cellular response to hydrogen peroxide1IEAHomo_sapiens(9606)Process
GO:0070828involved_in heterochromatin organization1IMPHomo_sapiens(9606)Process
GO:0070932involved_in histone H3 deacetylation1IEAHomo_sapiens(9606)Process
GO:0071300involved_in cellular response to retinoic acid1IEAHomo_sapiens(9606)Process
GO:0071560involved_in cellular response to transforming growth factor beta stimulus1IEAHomo_sapiens(9606)Process
GO:0160009enables histone decrotonylase activity1IDAHomo_sapiens(9606)Function
GO:0160010enables protein de-2-hydroxyisobutyrylase activity1IDAHomo_sapiens(9606)Function
GO:1902437involved_in positive regulation of male mating behavior1IEAHomo_sapiens(9606)Process
GO:1902455involved_in negative regulation of stem cell population maintenance1NASHomo_sapiens(9606)Process
GO:1902459involved_in positive regulation of stem cell population maintenance1NASHomo_sapiens(9606)Process
GO:1903351involved_in cellular response to dopamine1IEAHomo_sapiens(9606)Process
GO:1990841enables promoter-specific chromatin binding1IEAHomo_sapiens(9606)Function
GO:2000273acts_upstream_of positive regulation of signaling receptor activity1IMPHomo_sapiens(9606)Process
GO:2000736involved_in regulation of stem cell differentiation1NASHomo_sapiens(9606)Process
GO:2000757involved_in negative regulation of peptidyl-lysine acetylation1IEAHomo_sapiens(9606)Process

Expression