Functions and Diseases

RBP Type Canonical_RBPs
Diseases CancerCHIKVSARS-COV-OC43FlavivirusesHIVIAVRVSARS-COV-2SINVDengueZika
Drug N.A.
Main interacting RNAs mRNA
Moonlighting functions DUB
Localizations P-body
BulkPerturb-seq DataSet_01_114 DataSet_01_471

Description

Ensembl ID ENSG00000196419 Gene ID 2547 Accession 4055
Symbol XRCC6 Alias ML8;KU70;TLAA;CTC75;CTCBF;G22P1 Full Name X-ray repair cross complementing 6
Status Confidence Length 42886 bases Strand Plus strand
Position 22 : 41621163 - 41664048 RNA binding domain SAP
Summary The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus. [provided by RefSeq, Jul 2008]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000384082 SAP PF02037 6.6e-09 1
ENSP00000403679 SAP PF02037 6.6e-09 1
ENSP00000384941 SAP PF02037 8e-09 1
ENSP00000352257 SAP PF02037 9.1e-09 1
ENSP00000353192 SAP PF02037 9.1e-09 1
ENSP00000384257 SAP PF02037 9.1e-09 1

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal

Transcripts

Name Transcript ID bp Protein Translation ID
XRCC6-206 ENST00000428575 2148 559aa ENSP00000403679
XRCC6-207 ENST00000464116 359 No protein -
XRCC6-202 ENST00000360079 2122 609aa ENSP00000353192
XRCC6-203 ENST00000402580 2006 568aa ENSP00000384941
XRCC6-201 ENST00000359308 2709 609aa ENSP00000352257
XRCC6-205 ENST00000405878 2200 609aa ENSP00000384257
XRCC6-204 ENST00000405506 1958 559aa ENSP00000384082
XRCC6-208 ENST00000478914 550 No protein -

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000196419homo_sapiensENSP0000037597731.420814.3443homo_sapiensENSP0000035319237.766817.2414

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000196419homo_sapiensENSP0000035319286.863786.5353nomascus_leucogenysENSNLEP0000001893598.878598.5047
ENSG00000196419homo_sapiensENSP0000035319289.819489.8194pan_paniscusENSPPAP00000028250100100
ENSG00000196419homo_sapiensENSP0000035319299.835899.3432pongo_abeliiENSPPYP0000002598999.835899.3432
ENSG00000196419homo_sapiensENSP00000353192100100pan_troglodytesENSPTRP00000073204100100
ENSG00000196419homo_sapiensENSP00000353192100100pan_troglodytesENSPTRP00000073476100100
ENSG00000196419homo_sapiensENSP0000035319210099.6716gorilla_gorillaENSGGOP0000001549610099.6716
ENSG00000196419homo_sapiensENSP0000035319287.848978.4893ornithorhynchus_anatinusENSOANP0000001795080.572371.988
ENSG00000196419homo_sapiensENSP0000035319288.341578.1609sarcophilus_harrisiiENSSHAP0000001260988.196778.0328
ENSG00000196419homo_sapiensENSP0000035319284.400777.3399choloepus_hoffmanniENSCHOP0000000385484.262377.2131
ENSG00000196419homo_sapiensENSP0000035319293.267785.3859dasypus_novemcinctusENSDNOP0000001424893.267785.3859
ENSG00000196419homo_sapiensENSP0000035319263.71158.6207echinops_telfairiENSETEP0000001242664.026458.9109
ENSG00000196419homo_sapiensENSP0000035319299.835898.5222callithrix_jacchusENSCJAP0000005838199.835898.5222
ENSG00000196419homo_sapiensENSP0000035319250.738949.2611callithrix_jacchusENSCJAP0000006969595.076992.3077
ENSG00000196419homo_sapiensENSP0000035319299.835899.179cercocebus_atysENSCATP0000003956499.835899.179
ENSG00000196419homo_sapiensENSP0000035319299.671699.0148macaca_fascicularisENSMFAP0000003401399.835599.1776
ENSG00000196419homo_sapiensENSP0000035319299.835899.179macaca_mulattaENSMMUP0000007751799.835899.179
ENSG00000196419homo_sapiensENSP0000035319296.880195.7307macaca_nemestrinaENSMNEP0000002292795.469394.3366
ENSG00000196419homo_sapiensENSP0000035319299.835899.179papio_anubisENSPANP0000001342199.835899.179
ENSG00000196419homo_sapiensENSP0000035319296.880195.8949mandrillus_leucophaeusENSMLEP0000000442995.93594.9594
ENSG00000196419homo_sapiensENSP0000035319277.504171.9212tursiops_truncatusENSTTRP0000000638477.504171.9212
ENSG00000196419homo_sapiensENSP0000035319232.183926.9294vulpes_vulpesENSVVUP0000002478277.777865.0794
ENSG00000196419homo_sapiensENSP0000035319288.998480.9524vulpes_vulpesENSVVUP0000000445091.399783.1366
ENSG00000196419homo_sapiensENSP0000035319231.527128.8998vulpes_vulpesENSVVUP0000004034690.140882.6291
ENSG00000196419homo_sapiensENSP0000035319288.013180.4598mus_spretusMGP_SPRETEiJ_P004097790.235782.4916
ENSG00000196419homo_sapiensENSP0000035319292.939286.5353equus_asinusENSEASP0000504622388.16282.0872
ENSG00000196419homo_sapiensENSP0000035319292.610885.0575capra_hircusENSCHIP0000001029692.91685.3377
ENSG00000196419homo_sapiensENSP0000035319230.049326.2726loxodonta_africanaENSLAFP0000001857382.432472.0721
ENSG00000196419homo_sapiensENSP0000035319291.95483.908loxodonta_africanaENSLAFP0000000921891.65383.6334
ENSG00000196419homo_sapiensENSP0000035319293.267786.2069panthera_leoENSPLOP0000001801093.421186.3487
ENSG00000196419homo_sapiensENSP0000035319293.431984.0723ailuropoda_melanoleucaENSAMEP0000001644893.739784.3493
ENSG00000196419homo_sapiensENSP0000035319289.819481.7734bos_indicus_hybridENSBIXP0000502774081.157373.8872
ENSG00000196419homo_sapiensENSP0000035319294.909786.6995oryctolagus_cuniculusENSOCUP0000000600991.455783.5443
ENSG00000196419homo_sapiensENSP0000035319292.77586.0427equus_caballusENSECAP0000008121888.006281.6199
ENSG00000196419homo_sapiensENSP0000035319290.804682.4302canis_lupus_familiarisENSCAFP0084502282890.359582.0261
ENSG00000196419homo_sapiensENSP0000035319293.267786.0427panthera_pardusENSPPRP0000001012893.421186.1842
ENSG00000196419homo_sapiensENSP0000035319239.901537.11marmota_marmota_marmotaENSMMMP0000000402892.395485.9316
ENSG00000196419homo_sapiensENSP0000035319286.699579.6388balaenoptera_musculusENSBMSP0001001976293.783386.1456
ENSG00000196419homo_sapiensENSP0000035319284.072376.1905balaenoptera_musculusENSBMSP0001000245788.428380.1382
ENSG00000196419homo_sapiensENSP0000035319292.282483.908cavia_porcellusENSCPOP0000000320292.282483.908
ENSG00000196419homo_sapiensENSP0000035319293.431986.3711felis_catusENSFCAP0000001590793.585586.5132
ENSG00000196419homo_sapiensENSP0000035319281.773473.7274ursus_americanusENSUAMP0000001763794.497285.1992
ENSG00000196419homo_sapiensENSP0000035319282.594471.9212monodelphis_domesticaENSMODP0000005049879.462969.1943
ENSG00000196419homo_sapiensENSP0000035319291.95484.8933bison_bison_bisonENSBBBP0000000893492.25785.173
ENSG00000196419homo_sapiensENSP0000035319293.267785.5501monodon_monocerosENSMMNP0001502488993.267785.5501
ENSG00000196419homo_sapiensENSP0000035319232.512329.7209monodon_monocerosENSMMNP0001500473468.041262.1993
ENSG00000196419homo_sapiensENSP0000035319292.118284.5649sus_scrofaENSSSCP0000006950592.574384.9835
ENSG00000196419homo_sapiensENSP0000035319294.417188.3415microcebus_murinusENSMICP0000004609894.728288.6326
ENSG00000196419homo_sapiensENSP0000035319290.640482.1018octodon_degusENSODEP0000002152991.239782.6446
ENSG00000196419homo_sapiensENSP0000035319287.356379.3103jaculus_jaculusENSJJAP0000001476991.252182.8473
ENSG00000196419homo_sapiensENSP0000035319283.415477.0115ovis_aries_rambouilletENSOARP0002003192292.363685.2727
ENSG00000196419homo_sapiensENSP0000035319282.922875.2053ovis_aries_rambouilletENSOARP0002000268491.651583.1216
ENSG00000196419homo_sapiensENSP0000035319293.431984.4007ursus_maritimusENSUMAP0000002894093.739784.6787
ENSG00000196419homo_sapiensENSP0000035319287.848978.9819ochotona_princepsENSOPRP0000000221692.082682.7883
ENSG00000196419homo_sapiensENSP0000035319291.13382.4302delphinapterus_leucasENSDLEP0000002286691.282982.5658
ENSG00000196419homo_sapiensENSP0000035319233.004930.2135delphinapterus_leucasENSDLEP0000001164467.449761.745
ENSG00000196419homo_sapiensENSP0000035319287.027980.1314physeter_catodonENSPCTP0000501748592.819685.4641
ENSG00000196419homo_sapiensENSP0000035319231.034528.243physeter_catodonENSPCTP000050247779081.9048
ENSG00000196419homo_sapiensENSP0000035319285.221777.5041mus_caroliMGP_CAROLIEiJ_P003917189.022380.9605
ENSG00000196419homo_sapiensENSP0000035319290.640483.2512mus_musculusENSMUSP0000009796890.789583.3882
ENSG00000196419homo_sapiensENSP0000035319286.206977.3399dipodomys_ordiiENSDORP0000002767689.743680.5128
ENSG00000196419homo_sapiensENSP0000035319288.341579.6388mustela_putorius_furoENSMPUP0000001627992.758683.6207
ENSG00000196419homo_sapiensENSP0000035319299.671698.6864aotus_nancymaaeENSANAP0000000291399.671698.6864
ENSG00000196419homo_sapiensENSP0000035319278.160972.0854vicugna_pacosENSVPAP0000000242093.885686.5878
ENSG00000196419homo_sapiensENSP0000035319299.835899.179chlorocebus_sabaeusENSCSAP0000000209299.835899.179
ENSG00000196419homo_sapiensENSP0000035319282.594474.8768tupaia_belangeriENSTBEP0000001015586.426178.3505
ENSG00000196419homo_sapiensENSP0000035319291.95484.5649mesocricetus_auratusENSMAUP0000001891692.25784.8435
ENSG00000196419homo_sapiensENSP0000035319276.847369.4581phocoena_sinusENSPSNP0000000502688.135679.661
ENSG00000196419homo_sapiensENSP0000035319293.431985.8785phocoena_sinusENSPSNP0000000910887.003179.9694
ENSG00000196419homo_sapiensENSP0000035319292.939285.3859camelus_dromedariusENSCDRP0000500473692.939285.3859
ENSG00000196419homo_sapiensENSP0000035319294.252986.6995carlito_syrichtaENSTSYP0000002449894.098486.5574
ENSG00000196419homo_sapiensENSP0000035319293.431986.5353panthera_tigris_altaicaENSPTIP0000002213293.585586.6776
ENSG00000196419homo_sapiensENSP0000035319285.714377.0115rattus_norvegicusENSRNOP0000008196584.878176.2602
ENSG00000196419homo_sapiensENSP0000035319294.745587.6847prolemur_simusENSPSMP0000000148995.057787.9736
ENSG00000196419homo_sapiensENSP0000035319290.968884.2365microtus_ochrogasterENSMOCP0000001698291.419184.6535
ENSG00000196419homo_sapiensENSP0000035319278.817772.0854sorex_araneusENSSARP0000000725478.947472.2039
ENSG00000196419homo_sapiensENSP0000035319291.625683.5796peromyscus_maniculatus_bairdiiENSPEMP0000002771891.776383.7171
ENSG00000196419homo_sapiensENSP0000035319292.282485.2217bos_mutusENSBMUP0000002217091.830184.8039
ENSG00000196419homo_sapiensENSP0000035319290.31282.7586mus_spicilegusENSMSIP0000002131090.460582.8947
ENSG00000196419homo_sapiensENSP0000035319284.072377.3399cricetulus_griseus_chok1gshdENSCGRP0000101965589.824682.6316
ENSG00000196419homo_sapiensENSP0000035319292.939285.0575pteropus_vampyrusENSPVAP0000000110193.092185.1974
ENSG00000196419homo_sapiensENSP0000035319293.431984.8933myotis_lucifugusENSMLUP0000000228593.739785.173
ENSG00000196419homo_sapiensENSP0000035319289.49178.4893vombatus_ursinusENSVURP0001000194389.49178.4893
ENSG00000196419homo_sapiensENSP0000035319289.49180.4598rhinolophus_ferrumequinumENSRFEP0001002619384.89176.324
ENSG00000196419homo_sapiensENSP0000035319288.505778.4893neovison_visonENSNVIP0000000032588.797478.7479
ENSG00000196419homo_sapiensENSP0000035319291.95484.7291bos_taurusENSBTAP0000000802091.503384.3137
ENSG00000196419homo_sapiensENSP0000035319253.20248.9327heterocephalus_glaber_femaleENSHGLP0000005969090.502883.2402
ENSG00000196419homo_sapiensENSP0000035319291.297283.908heterocephalus_glaber_femaleENSHGLP0000003649591.447484.0461
ENSG00000196419homo_sapiensENSP0000035319250.738950.0821rhinopithecus_bietiENSRBIP0000001118294.207392.9878
ENSG00000196419homo_sapiensENSP0000035319292.77584.5649canis_lupus_dingoENSCAFP0002000223992.927684.7039
ENSG00000196419homo_sapiensENSP0000035319293.596188.1773sciurus_vulgarisENSSVLP0000502696993.596188.1773
ENSG00000196419homo_sapiensENSP0000035319289.655279.1461phascolarctos_cinereusENSPCIP0000003572989.508279.0164
ENSG00000196419homo_sapiensENSP0000035319290.147880.624procavia_capensisENSPCAP0000001400690.296180.7566
ENSG00000196419homo_sapiensENSP0000035319292.446683.5796nannospalax_galiliENSNGAP0000001167192.598783.7171
ENSG00000196419homo_sapiensENSP0000035319292.282485.0575bos_grunniensENSBGRP0000001410891.830184.6405
ENSG00000196419homo_sapiensENSP0000035319292.77585.3859chinchilla_lanigeraENSCLAP0000002428092.77585.3859
ENSG00000196419homo_sapiensENSP0000035319292.446685.7143cervus_hanglu_yarkandensisENSCHYP0000003432488.661482.2047
ENSG00000196419homo_sapiensENSP0000035319292.610884.5649catagonus_wagneriENSCWAP0000001507192.763284.7039
ENSG00000196419homo_sapiensENSP0000035319294.088788.3415ictidomys_tridecemlineatusENSSTOP0000000852094.088788.3415
ENSG00000196419homo_sapiensENSP0000035319294.581387.3563otolemur_garnettiiENSOGAP0000000790994.736887.5
ENSG00000196419homo_sapiensENSP0000035319281.609279.3103cebus_imitatorENSCCAP0000003564698.027695.2663
ENSG00000196419homo_sapiensENSP0000035319294.088788.1773urocitellus_parryiiENSUPAP0001000724294.088788.1773
ENSG00000196419homo_sapiensENSP0000035319292.282485.2217moschus_moschiferusENSMMSP0000001772492.586585.5025
ENSG00000196419homo_sapiensENSP0000035319234.64734.3186rhinopithecus_roxellanaENSRROP0000002758095.909195
ENSG00000196419homo_sapiensENSP0000035319290.476282.4302mus_pahariMGP_PahariEiJ_P004251990.62582.5658
ENSG00000196419homo_sapiensENSP0000035319277.504172.578propithecus_coquereliENSPCOP0000002930295.161389.1129
ENSG00000196419homo_sapiensENSP0000035319244.499225.4516caenorhabditis_elegansY47D3A.4.139.911622.8277
ENSG00000196419homo_sapiensENSP0000035319245.97724.7947drosophila_melanogasterFBpp008186144.37423.9303
ENSG00000196419homo_sapiensENSP0000035319220.525512.8079drosophila_melanogasterFBpp030386034.818921.727
ENSG00000196419homo_sapiensENSP0000035319256.321834.8112ciona_intestinalisENSCINP0000000116656.882335.1575
ENSG00000196419homo_sapiensENSP0000035319241.871930.7061petromyzon_marinusENSPMAP0000000571469.86351.2329
ENSG00000196419homo_sapiensENSP0000035319241.543528.7356eptatretus_burgeriENSEBUP0000002465468.194147.1698
ENSG00000196419homo_sapiensENSP0000035319279.967262.7258callorhinchus_miliiENSCMIP0000000966673.013557.2714
ENSG00000196419homo_sapiensENSP0000035319274.055859.7701latimeria_chalumnaeENSLACP0000001203173.934459.6721
ENSG00000196419homo_sapiensENSP0000035319262.233244.8276lepisosteus_oculatusENSLOCP0000001417375.49854.3825
ENSG00000196419homo_sapiensENSP0000035319275.533757.4713clupea_harengusENSCHAP0000002612374.313456.5428
ENSG00000196419homo_sapiensENSP0000035319276.683158.6207danio_rerioENSDARP0000009663676.557458.5246
ENSG00000196419homo_sapiensENSP0000035319277.175758.4565carassius_auratusENSCARP0000000738776.298757.7922
ENSG00000196419homo_sapiensENSP0000035319277.504157.6355astyanax_mexicanusENSAMXP0000000775177.504157.6355
ENSG00000196419homo_sapiensENSP0000035319275.533757.3071ictalurus_punctatusENSIPUP0000000106875.533757.3071
ENSG00000196419homo_sapiensENSP0000035319275.205355.3366esox_luciusENSELUP0000003996775.08255.2459
ENSG00000196419homo_sapiensENSP0000035319274.055856.6502electrophorus_electricusENSEEEP0000002373071.929855.0239
ENSG00000196419homo_sapiensENSP0000035319264.203646.3054oncorhynchus_kisutchENSOKIP0000511708166.383747.8778
ENSG00000196419homo_sapiensENSP0000035319273.727454.3514oncorhynchus_kisutchENSOKIP0000501570172.653753.5599
ENSG00000196419homo_sapiensENSP0000035319269.129750.2463oncorhynchus_mykissENSOMYP0000003732969.933650.8306
ENSG00000196419homo_sapiensENSP0000035319271.75752.2167oncorhynchus_mykissENSOMYP0000009838862.428645.4286
ENSG00000196419homo_sapiensENSP0000035319238.916329.064salmo_salarENSSSAP0000011546865.109948.6264
ENSG00000196419homo_sapiensENSP0000035319274.712654.6798salmo_salarENSSSAP0000000337373.387153.7097
ENSG00000196419homo_sapiensENSP0000035319271.921252.2167salmo_truttaENSSTUP0000007658466.870248.5496
ENSG00000196419homo_sapiensENSP0000035319274.2255.0082salmo_truttaENSSTUP0000007576373.977154.8282
ENSG00000196419homo_sapiensENSP0000035319275.041154.1872gadus_morhuaENSGMOP0000002679474.188353.5714
ENSG00000196419homo_sapiensENSP0000035319276.190557.1429fundulus_heteroclitusENSFHEP0000003114276.065657.0492
ENSG00000196419homo_sapiensENSP0000035319276.354755.665poecilia_reticulataENSPREP0000003095470.992451.7557
ENSG00000196419homo_sapiensENSP0000035319275.697955.5008xiphophorus_maculatusENSXMAP0000003313075.573855.4098
ENSG00000196419homo_sapiensENSP0000035319275.369555.1724oryzias_latipesENSORLP0000000302675.122754.9918
ENSG00000196419homo_sapiensENSP0000035319273.070655.0082cyclopterus_lumpusENSCLMP0000504981472.712454.7386
ENSG00000196419homo_sapiensENSP0000035319275.369556.6502oreochromis_niloticusENSONIP0000004324872.511854.5024
ENSG00000196419homo_sapiensENSP0000035319269.786552.0525haplochromis_burtoniENSHBUP0000002100675.088356.0071
ENSG00000196419homo_sapiensENSP0000035319275.205355.9934astatotilapia_callipteraENSACLP0000002742475.08255.9016
ENSG00000196419homo_sapiensENSP0000035319274.055854.844sparus_aurataENSSAUP0001000670671.135652.6814
ENSG00000196419homo_sapiensENSP0000035319276.026357.1429lates_calcariferENSLCAP0001005677675.040556.4019
ENSG00000196419homo_sapiensENSP0000035319282.101866.3383xenopus_tropicalisENSXETP0000008719879.113963.924
ENSG00000196419homo_sapiensENSP0000035319285.550174.0558chrysemys_picta_belliiENSCPBP0000002910885.409873.9344
ENSG00000196419homo_sapiensENSP0000035319284.564973.5632sphenodon_punctatusENSSPUP0000001563984.426273.4426
ENSG00000196419homo_sapiensENSP0000035319283.579670.6076crocodylus_porosusENSCPRP0000502753483.169970.2614
ENSG00000196419homo_sapiensENSP0000035319279.80365.5172laticauda_laticaudataENSLLTP0000000136881.40766.8342
ENSG00000196419homo_sapiensENSP0000035319281.937666.9951notechis_scutatusENSNSUP0000000463481.402966.5579
ENSG00000196419homo_sapiensENSP0000035319282.101867.3235pseudonaja_textilisENSPTXP0000000001981.833167.1031
ENSG00000196419homo_sapiensENSP0000035319285.385969.1297anas_platyrhynchos_platyrhynchosENSAPLP0000000400784.278868.2334
ENSG00000196419homo_sapiensENSP0000035319284.400769.6223gallus_gallusENSGALP0001001454379.198865.3313
ENSG00000196419homo_sapiensENSP0000035319283.743869.2939meleagris_gallopavoENSMGAP0000001276483.061968.7296
ENSG00000196419homo_sapiensENSP0000035319283.251268.1445serinus_canariaENSSCAP0000000749881.1266.4
ENSG00000196419homo_sapiensENSP0000035319283.90869.6223parus_majorENSPMJP0000000429183.360569.168
ENSG00000196419homo_sapiensENSP0000035319284.400771.2644anolis_carolinensisENSACAP0000000446383.713470.684
ENSG00000196419homo_sapiensENSP0000035319275.697956.486neolamprologus_brichardiENSNBRP0000000538375.573856.3934
ENSG00000196419homo_sapiensENSP0000035319282.101867.8161naja_najaENSNNAP0000000641881.833167.5941
ENSG00000196419homo_sapiensENSP0000035319283.579669.9507podarcis_muralisENSPMRP0000003136283.306169.7218
ENSG00000196419homo_sapiensENSP0000035319285.550171.2644geospiza_fortisENSGFOP0000001157385.270171.0311
ENSG00000196419homo_sapiensENSP0000035319284.729170.6076taeniopygia_guttataENSTGUP0000001018684.313770.2614
ENSG00000196419homo_sapiensENSP0000035319279.638862.89erpetoichthys_calabaricusENSECRP0000003109980.29863.4106
ENSG00000196419homo_sapiensENSP0000035319275.205355.8292kryptolebias_marmoratusENSKMAP0000000284175.08255.7377
ENSG00000196419homo_sapiensENSP0000035319275.041161.9048salvator_merianaeENSSMRP0000001965173.709760.8064
ENSG00000196419homo_sapiensENSP0000035319256.48641.8719oryzias_javanicusENSOJAP0000000829770.636652.3614
ENSG00000196419homo_sapiensENSP0000035319275.369555.8292amphilophus_citrinellusENSACIP0000002746875.245955.7377
ENSG00000196419homo_sapiensENSP0000035319274.876856.1576dicentrarchus_labraxENSDLAP0000504299774.509855.8824
ENSG00000196419homo_sapiensENSP0000035319275.205355.3366amphiprion_perculaENSAPEP0000002914775.08255.2459
ENSG00000196419homo_sapiensENSP0000035319270.443451.5599oryzias_sinensisENSOSIP0000002614275.263255.0877
ENSG00000196419homo_sapiensENSP0000035319275.697955.665oryzias_sinensisENSOSIP0000002902175.450155.4828
ENSG00000196419homo_sapiensENSP0000035319235.796430.5419pelodiscus_sinensisENSPSIP0000001855384.824972.3735
ENSG00000196419homo_sapiensENSP0000035319245.15639.4089pelodiscus_sinensisENSPSIP0000000969585.669874.7664
ENSG00000196419homo_sapiensENSP0000035319286.206973.8916gopherus_evgoodeiENSGEVP0000500330786.065673.7705
ENSG00000196419homo_sapiensENSP0000035319285.221773.5632chelonoidis_abingdoniiENSCABP0000003131785.08273.4426
ENSG00000196419homo_sapiensENSP0000035319276.026356.3218seriola_dumeriliENSSDUP0000001030775.901656.2295
ENSG00000196419homo_sapiensENSP0000035319275.533755.3366cottoperca_gobioENSCGOP0000002809372.555253.1546
ENSG00000196419homo_sapiensENSP0000035319285.714369.9507anser_brachyrhynchusENSABRP0000000512084.602969.0438
ENSG00000196419homo_sapiensENSP0000035319275.205354.5156gasterosteus_aculeatusENSGACP0000000645574.1153.7217
ENSG00000196419homo_sapiensENSP0000035319276.518956.1576cynoglossus_semilaevisENSCSEP0000003185874.799454.8957
ENSG00000196419homo_sapiensENSP0000035319275.862155.5008poecilia_formosaENSPFOP0000001725775.737755.4098
ENSG00000196419homo_sapiensENSP0000035319273.39954.023myripristis_murdjanENSMMDP0000501976172.682953.4959
ENSG00000196419homo_sapiensENSP0000035319275.697956.486sander_luciopercaENSSLUP0000006077774.716455.7536
ENSG00000196419homo_sapiensENSP0000035319284.072369.6223strigops_habroptilaENSSHBP0000500460883.797169.3944
ENSG00000196419homo_sapiensENSP0000035319275.041155.0082amphiprion_ocellarisENSAOCP0000003040574.91854.918
ENSG00000196419homo_sapiensENSP0000035319285.714374.0558terrapene_carolina_triunguisENSTMTP0000001168085.573873.9344
ENSG00000196419homo_sapiensENSP0000035319274.384255.3366hucho_huchoENSHHUP0000008052173.419854.6191
ENSG00000196419homo_sapiensENSP0000035319274.384254.6798hucho_huchoENSHHUP0000007282972.829653.537
ENSG00000196419homo_sapiensENSP0000035319275.533755.5008betta_splendensENSBSLP0000004845473.717954.1667
ENSG00000196419homo_sapiensENSP0000035319270.607653.6946pygocentrus_nattereriENSPNAP0000000813277.617359.0253
ENSG00000196419homo_sapiensENSP0000035319275.205355.8292anabas_testudineusENSATEP0000001010675.08255.7377
ENSG00000196419homo_sapiensENSP0000035319225.615817.0772ciona_savignyiENSCSAVP0000000170366.101744.0678
ENSG00000196419homo_sapiensENSP0000035319235.303817.0772saccharomyces_cerevisiaeYMR284W35.714317.2757
ENSG00000196419homo_sapiensENSP0000035319275.862155.665seriola_lalandi_dorsalisENSSLDP0000001253375.737755.5738
ENSG00000196419homo_sapiensENSP0000035319275.205355.5008labrus_bergyltaENSLBEP0000000349073.990354.6042
ENSG00000196419homo_sapiensENSP0000035319274.876855.9934pundamilia_nyerereiENSPNYP0000000492070.697752.8682
ENSG00000196419homo_sapiensENSP0000035319274.384254.5156mastacembelus_armatusENSMAMP0000000500374.262354.4262
ENSG00000196419homo_sapiensENSP0000035319275.205356.3218stegastes_partitusENSSPAP0000002014475.08256.2295
ENSG00000196419homo_sapiensENSP0000035319272.742252.5452oncorhynchus_tshawytschaENSOTSP0000502997946.92833.8983
ENSG00000196419homo_sapiensENSP0000035319268.144550.5747oncorhynchus_tshawytschaENSOTSP0000509508971.428653.012
ENSG00000196419homo_sapiensENSP0000035319275.205355.665acanthochromis_polyacanthusENSAPOP0000001023075.328955.7566
ENSG00000196419homo_sapiensENSP0000035319285.057571.1002aquila_chrysaetos_chrysaetosENSACCP0002001599082.091968.6212
ENSG00000196419homo_sapiensENSP0000035319274.384255.8292nothobranchius_furzeriENSNFUP0001503942868.325851.2821
ENSG00000196419homo_sapiensENSP0000035319275.533755.9934cyprinodon_variegatusENSCVAP0000002069673.717954.6474
ENSG00000196419homo_sapiensENSP0000035319276.354756.3218denticeps_clupeoidesENSDCDP0000004461276.229556.2295
ENSG00000196419homo_sapiensENSP0000035319275.697956.486larimichthys_croceaENSLCRP0000502142574.959455.935
ENSG00000196419homo_sapiensENSP0000035319274.2255.0082takifugu_rubripesENSTRUP0000006887274.2255.0082
ENSG00000196419homo_sapiensENSP0000035319284.893370.6076ficedula_albicollisENSFALP0000001245384.477170.2614
ENSG00000196419homo_sapiensENSP0000035319273.070653.8588hippocampus_comesENSHCOP0000000772973.070653.8588
ENSG00000196419homo_sapiensENSP0000035319276.683157.9639cyprinus_carpio_carpioENSCCRP0000017604476.557457.8689
ENSG00000196419homo_sapiensENSP0000035319259.934344.1708cyprinus_carpio_carpioENSCCRP0000000694671.709252.8487
ENSG00000196419homo_sapiensENSP0000035319283.743869.7865coturnix_japonicaENSCJPP0000501044683.061969.2182
ENSG00000196419homo_sapiensENSP0000035319276.026355.1724poecilia_latipinnaENSPLAP0000001963375.901655.082
ENSG00000196419homo_sapiensENSP0000035319277.011558.9491sinocyclocheilus_grahamiENSSGRP0000007310376.885258.8525
ENSG00000196419homo_sapiensENSP0000035319276.683157.3071sinocyclocheilus_grahamiENSSGRP0000010523476.307257.0261
ENSG00000196419homo_sapiensENSP0000035319275.205355.9934maylandia_zebraENSMZEP0000503765475.08255.9016
ENSG00000196419homo_sapiensENSP0000035319271.264454.3514tetraodon_nigroviridisENSTNIP0000001592773.06455.7239
ENSG00000196419homo_sapiensENSP0000035319276.354760.2627paramormyrops_kingsleyaeENSPKIP0000001839576.229560.1639
ENSG00000196419homo_sapiensENSP0000035319274.384258.7849scleropages_formosusENSSFOP0001506611472.133857.0064
ENSG00000196419homo_sapiensENSP0000035319281.116664.8604leptobrachium_leishanenseENSLLEP0000003754781.518265.1815
ENSG00000196419homo_sapiensENSP0000035319275.533756.486scophthalmus_maximusENSSMAP0000001053475.286456.3011
ENSG00000196419homo_sapiensENSP0000035319274.876855.0082oryzias_melastigmaENSOMEP0000002688274.631854.8282

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0000723involved_in telomere maintenance2IBA,TASHomo_sapiens(9606)Process
GO:0000725involved_in recombinational repair1NASHomo_sapiens(9606)Process
GO:0000781located_in chromosome, telomeric region1HDAHomo_sapiens(9606)Component
GO:0000783part_of nuclear telomere cap complex1TASHomo_sapiens(9606)Component
GO:0000976enables transcription cis-regulatory region binding1IDAHomo_sapiens(9606)Function
GO:0002218involved_in activation of innate immune response1IDAHomo_sapiens(9606)Process
GO:0003677enables DNA binding1NASHomo_sapiens(9606)Function
GO:0003678enables DNA helicase activity1IDAHomo_sapiens(9606)Function
GO:0003684enables damaged DNA binding1IEAHomo_sapiens(9606)Function
GO:0003690contributes_to double-stranded DNA binding1IBAHomo_sapiens(9606)Function
GO:0003691contributes_to double-stranded telomeric DNA binding1IDAHomo_sapiens(9606)Function
GO:0003723enables RNA binding1HDAHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005524enables ATP binding1IEAHomo_sapiens(9606)Function
GO:0005576located_in extracellular region1TASHomo_sapiens(9606)Component
GO:0005634located_in nucleus1TASHomo_sapiens(9606)Component
GO:0005654located_in nucleoplasm2IDA,TASHomo_sapiens(9606)Component
GO:0005667part_of transcription regulator complex1IDAHomo_sapiens(9606)Component
GO:0005730located_in nucleolus1IDAHomo_sapiens(9606)Component
GO:0005829located_in cytosol1TASHomo_sapiens(9606)Component
GO:0006266involved_in DNA ligation1TASHomo_sapiens(9606)Process
GO:0006303involved_in double-strand break repair via nonhomologous end joining4IBA,IMP,NAS,TASHomo_sapiens(9606)Process
GO:0008094enables ATP-dependent activity, acting on DNA1IDAHomo_sapiens(9606)Function
GO:0016020located_in membrane1HDAHomo_sapiens(9606)Component
GO:0016887enables ATP hydrolysis activity1IDAHomo_sapiens(9606)Function
GO:0030332enables cyclin binding1IPIHomo_sapiens(9606)Function
GO:0032508involved_in DNA duplex unwinding1IEAHomo_sapiens(9606)Process
GO:0032991part_of protein-containing complex1IDAHomo_sapiens(9606)Component
GO:0032993part_of protein-DNA complex1IDAHomo_sapiens(9606)Component
GO:0034774located_in secretory granule lumen1TASHomo_sapiens(9606)Component
GO:0042162enables telomeric DNA binding1IBAHomo_sapiens(9606)Function
GO:0043564part_of Ku70:Ku80 complex3IBA,IDA,IPIHomo_sapiens(9606)Component
GO:0044877enables protein-containing complex binding1IPIHomo_sapiens(9606)Function
GO:0045027contributes_to DNA end binding1IDAHomo_sapiens(9606)Function
GO:0045087involved_in innate immune response1IEAHomo_sapiens(9606)Process
GO:0045621involved_in positive regulation of lymphocyte differentiation1ISSHomo_sapiens(9606)Process
GO:0045860involved_in positive regulation of protein kinase activity1IDAHomo_sapiens(9606)Process
GO:0045892involved_in negative regulation of DNA-templated transcription1IMPHomo_sapiens(9606)Process
GO:0045893involved_in positive regulation of DNA-templated transcription2IDA,IMPHomo_sapiens(9606)Process
GO:0045944involved_in positive regulation of transcription by RNA polymerase II1IMPHomo_sapiens(9606)Process
GO:0048660involved_in regulation of smooth muscle cell proliferation1IMPHomo_sapiens(9606)Process
GO:0051575enables 5-deoxyribose-5-phosphate lyase activity1IMPHomo_sapiens(9606)Function
GO:0070418part_of DNA-dependent protein kinase complex1IPIHomo_sapiens(9606)Component
GO:0070419part_of nonhomologous end joining complex1IDAHomo_sapiens(9606)Component
GO:0071475involved_in cellular hyperosmotic salinity response1IEAHomo_sapiens(9606)Process
GO:0071480involved_in cellular response to gamma radiation1IDAHomo_sapiens(9606)Process
GO:0071481involved_in cellular response to X-ray1IEAHomo_sapiens(9606)Process
GO:0097110enables scaffold protein binding1IPIHomo_sapiens(9606)Function
GO:0097680involved_in double-strand break repair via classical nonhomologous end joining1IDAHomo_sapiens(9606)Process
GO:1904813located_in ficolin-1-rich granule lumen1TASHomo_sapiens(9606)Component

Expression