Welcome to
RBP World!
Description
| Ensembl ID | ENSG00000189403 | Gene ID | 3146 | Accession | 4983 |
| Symbol | HMGB1 | Alias | HMG1;HMG3;HMG-1;SBP-1 | Full Name | high mobility group box 1 |
| Status | Confidence | Length | 160894 bases | Strand | Minus strand |
| Position | 13 : 30456704 - 30617597 | RNA binding domain | N.A. | ||
| Summary | This gene encodes a protein that belongs to the High Mobility Group-box superfamily. The encoded non-histone, nuclear DNA-binding protein regulates transcription, and is involved in organization of DNA. This protein plays a role in several cellular processes, including inflammation, cell differentiation and tumor cell migration. Multiple pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Sep 2015] | ||||
RNA binding domains (RBDs)
| Protein | Domain | Pfam ID | E-value | Domain number |
|---|
RNA binding proteomes (RBPomes)
| Pubmed ID | Full Name | Cell | Author | Time | Doi |
|---|
Literatures on RNA binding capacity
| Pubmed ID | Title | Author | Time | Journal |
|---|---|---|---|---|
| 34680084 | Interactions of HMGB Proteins with the Genome and the Impact on Disease. | K Calvin Voong | 2021-10-02 | Biomolecules |
| 36895013 | Potential antiviral activities of chrysin against hepatitis B virus. | Ahmad Sajad Bhat | 2023-03-09 | Gut pathogens |
| 27764250 | Histone H2B-IFI16 Recognition of Nuclear Herpesviral Genome Induces Cytoplasmic Interferon-β Responses. | Jawed Iqbal | 2016-10-01 | PLoS pathogens |
| 35706377 | Molecular insights into the multifaceted functions and therapeutic targeting of high mobility group box 1 in metabolic diseases. | Zhipeng Tao | 2022-07-01 | Journal of cellular and molecular medicine |
| 33713214 | Release mechanisms of major DAMPs. | Atsushi Murao | 2021-04-01 | Apoptosis : an international journal on programmed cell death |
| 35628437 | Endothelial Dysfunction Induced by Extracellular Neutrophil Traps Plays Important Role in the Occurrence and Treatment of Extracellular Neutrophil Traps-Related Disease. | Shuyang Yu | 2022-05-17 | International journal of molecular sciences |
| 32016422 | Concurrent binding to DNA and RNA facilitates the pluripotency reprogramming activity of Sox2. | Linlin Hou | 2020-04-17 | Nucleic acids research |
| 36147548 | Translational and Clinical Significance of DAMPs, PAMPs, and PRRs in Trauma-induced Inflammation. | Vikrant Rai | 2022-01-01 | Archives of clinical and biomedical research |
| 22301850 | Accessory molecules for Toll-like receptors and their function. | C Clarissa Lee | 2012-02-03 | Nature reviews. Immunology |
| 33572313 | LncRNAs and Immunity: Coding the Immune System with Noncoding Oligonucleotides. | Marco Bocchetti | 2021-02-09 | International journal of molecular sciences |
| 26536345 | Mitochondrial Regulation of Inflammasome Activation in Chronic Obstructive Pulmonary Disease. | Min Chang Yoon | 2016-01-01 | Journal of innate immunity |
| 26545237 | Mitochondrial Transcription Factor A (TFAM) Binds to RNA Containing 4-Way Junctions and Mitochondrial tRNA. | A Timothy Brown | 2015-01-01 | PloS one |
| 24376467 | A Module Analysis Approach to Investigate Molecular Mechanism of TCM Formula: A Trial on Shu-feng-jie-du Formula. | Jianglong Song | 2013-01-01 | Evidence-based complementary and alternative medicine : eCAM |
| 26656705 | HMGB1 Promotes Hepatitis C Virus Replication by Interaction with Stem-Loop 4 in the Viral 5' Untranslated Region. | Rong Yu | 2015-12-09 | Journal of virology |
| 33128580 | HMGB1: an important regulator of myeloid differentiation and acute myeloid leukemia as well as a promising therapeutic target. | Lulu Liu | 2021-01-01 | Journal of molecular medicine (Berlin, Germany) |
| 32604223 | Therapeutic Potential of B-1a Cells in COVID-19. | Monowar Aziz | 2020-11-01 | Shock (Augusta, Ga.) |
| 29507356 | Innate immune responses to trauma. | Markus Huber-Lang | 2018-04-01 | Nature immunology |
| 27165399 | The cis-acting replication element of the Hepatitis C virus genome recruits host factors that influence viral replication and translation. | Pablo Ríos-Marco | 2016-05-11 | Scientific reports |
| 34166567 | HMGB1 coordinates SASP-related chromatin folding and RNA homeostasis on the path to senescence. | Konstantinos Sofiadis | 2021-06-01 | Molecular systems biology |
| 34557518 | Systematic Analysis of the Impact of R-Methylation on RBPs-RNA Interactions: A Proteomic Approach. | Marianna Maniaci | 2021-01-01 | Frontiers in molecular biosciences |
| 26854151 | Circulating HMGB1 and RAGE as Clinical Biomarkers in Malignant and Autoimmune Diseases. | Christin Pilzweger | 2015-06-16 | Diagnostics (Basel, Switzerland) |
| 31538427 | microRNA-146a Promotes Growth of Acute Leukemia Cells by Downregulating Ciliary Neurotrophic Factor Receptor and Activating JAK2/STAT3 Signaling. | Lei Wang | 2019-10-01 | Yonsei medical journal |
| 28049065 | Nucleic acid scavenging microfiber mesh inhibits trauma-induced inflammation and thrombosis. | Jaewoo Lee | 2017-03-01 | Biomaterials |
| 28969092 | The dual role and therapeutic potential of high-mobility group box 1 in cancer. | Si-Jia He | 2017-09-08 | Oncotarget |
| 35701499 | CXCL4 synergizes with TLR8 for TBK1-IRF5 activation, epigenomic remodeling and inflammatory response in human monocytes. | Chao Yang | 2022-06-14 | Nature communications |
Transcripts
| Name | Transcript ID | bp | Protein | Translation ID |
|---|---|---|---|---|
| HMGB1-203 | ENST00000341423 | 5456 | 215aa | ENSP00000345347 |
| HMGB1-206 | ENST00000405805 | 4199 | 215aa | ENSP00000384678 |
| HMGB1-202 | ENST00000339872 | 2319 | 215aa | ENSP00000343040 |
| HMGB1-204 | ENST00000399489 | 1727 | 158aa | ENSP00000382412 |
| HMGB1-205 | ENST00000399494 | 1282 | 215aa | ENSP00000382417 |
| HMGB1-201 | ENST00000326004 | 821 | 158aa | ENSP00000369904 |
| HMGB1-208 | ENST00000490788 | 425 | No protein | - |
| HMGB1-207 | ENST00000468384 | 503 | No protein | - |
Phenotypes
| ensgID | Trait | pValue | Pubmed ID |
|---|---|---|---|
| 20416 | Triglycerides | 9.785e-005 | - |
| 20417 | Triglycerides | 9.785e-005 | - |
| 20418 | Triglycerides | 9.785e-005 | - |
| 29291 | Cholesterol, HDL | 8.6720000E-005 | - |
| 30048 | Lipids | 3.1590000E-005 | - |
| 102231 | Hippocampus | 7E-6 | 21116278 |
GWAS
| ensgID | SNP | Chromosome | Position | Trait | PubmedID | Or or BEAT | EFO ID |
|---|
Protein-Protein Interaction (PPI)
Paralogs
| Ensembl ID | Source | Target | ||||||
|---|---|---|---|---|---|---|---|---|
| Species | Protein ID | Perc_pos | Perc_id | Species | Protein ID | Perc_pos | Perc_id | |
| ENSG00000189403 | homo_sapiens | ENSP00000508468 | 97.1564 | 94.7867 | homo_sapiens | ENSP00000345347 | 95.3488 | 93.0233 |
| ENSG00000189403 | homo_sapiens | ENSP00000328269 | 22.082 | 13.2492 | homo_sapiens | ENSP00000345347 | 32.5581 | 19.5349 |
| ENSG00000189403 | homo_sapiens | ENSP00000359393 | 87 | 75.5 | homo_sapiens | ENSP00000345347 | 80.9302 | 70.2326 |
| ENSG00000189403 | homo_sapiens | ENSP00000505691 | 61.828 | 38.7097 | homo_sapiens | ENSP00000345347 | 53.4884 | 33.4884 |
| ENSG00000189403 | homo_sapiens | ENSP00000296503 | 90.4306 | 81.3397 | homo_sapiens | ENSP00000345347 | 87.907 | 79.0698 |
| ENSG00000189403 | homo_sapiens | ENSP00000485108 | 18.3206 | 10.1781 | homo_sapiens | ENSP00000345347 | 33.4884 | 18.6047 |
| ENSG00000189403 | homo_sapiens | ENSP00000354842 | 19.2015 | 11.4068 | homo_sapiens | ENSP00000345347 | 46.9767 | 27.907 |
| ENSG00000189403 | homo_sapiens | ENSP00000344724 | 19.5652 | 12.0553 | homo_sapiens | ENSP00000345347 | 46.0465 | 28.3721 |
| ENSG00000189403 | homo_sapiens | ENSP00000343023 | 10.8475 | 5.53672 | homo_sapiens | ENSP00000345347 | 44.6512 | 22.7907 |
| ENSG00000189403 | homo_sapiens | ENSP00000219746 | 17.5347 | 10.9375 | homo_sapiens | ENSP00000345347 | 46.9767 | 29.3023 |
| ENSG00000189403 | homo_sapiens | ENSP00000397911 | 14.1379 | 7.75862 | homo_sapiens | ENSP00000345347 | 38.1395 | 20.9302 |
| ENSG00000189403 | homo_sapiens | ENSP00000216106 | 18.3028 | 12.4792 | homo_sapiens | ENSP00000345347 | 51.1628 | 34.8837 |
| ENSG00000189403 | homo_sapiens | ENSP00000390669 | 12.9581 | 8.11518 | homo_sapiens | ENSP00000345347 | 46.0465 | 28.8372 |
| ENSG00000189403 | homo_sapiens | ENSP00000323967 | 19.2214 | 10.4623 | homo_sapiens | ENSP00000345347 | 36.7442 | 20 |
| ENSG00000189403 | homo_sapiens | ENSP00000258381 | 12.202 | 5.8906 | homo_sapiens | ENSP00000345347 | 40.4651 | 19.5349 |
| ENSG00000189403 | homo_sapiens | ENSP00000375899 | 10.842 | 5.88235 | homo_sapiens | ENSP00000345347 | 43.7209 | 23.7209 |
| ENSG00000189403 | homo_sapiens | ENSP00000278412 | 9.87306 | 4.23131 | homo_sapiens | ENSP00000345347 | 32.5581 | 13.9535 |
| ENSG00000189403 | homo_sapiens | ENSP00000336856 | 21.3256 | 10.951 | homo_sapiens | ENSP00000345347 | 34.4186 | 17.6744 |
| ENSG00000189403 | homo_sapiens | ENSP00000393080 | 16.9082 | 10.306 | homo_sapiens | ENSP00000345347 | 48.8372 | 29.7674 |
| ENSG00000189403 | homo_sapiens | ENSP00000420588 | 36.9919 | 19.9187 | homo_sapiens | ENSP00000345347 | 42.3256 | 22.7907 |
Orthologs
| Ensembl ID | Source | Target | ||||||
|---|---|---|---|---|---|---|---|---|
| Species | Protein ID | Perc_pos | Perc_id | Species | Protein ID | Perc_pos | Perc_id | |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 58.1395 | 56.7442 | nomascus_leucogenys | ENSNLEP00000028612 | 93.2836 | 91.0448 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 78.1395 | 74.4186 | nomascus_leucogenys | ENSNLEP00000036881 | 93.8548 | 89.3855 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 60 | 57.6744 | pongo_abelii | ENSPPYP00000027281 | 80.625 | 77.5 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 96.7442 | 96.2791 | pan_troglodytes | ENSPTRP00000072328 | 99.0476 | 98.5714 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 100 | 99.5349 | pan_troglodytes | ENSPTRP00000074016 | 100 | 99.5349 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 100 | 100 | gorilla_gorilla | ENSGGOP00000027176 | 100 | 100 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 98.1395 | 93.9535 | ornithorhynchus_anatinus | ENSOANP00000023193 | 98.1395 | 93.9535 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 98.6047 | 95.814 | sarcophilus_harrisii | ENSSHAP00000016495 | 98.1481 | 95.3704 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 50.2326 | 50.2326 | erinaceus_europaeus | ENSEEUP00000000980 | 68.7898 | 68.7898 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 98.6047 | 98.6047 | callithrix_jacchus | ENSCJAP00000015417 | 99.0654 | 99.0654 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 100 | 100 | cercocebus_atys | ENSCATP00000005202 | 100 | 100 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 100 | 100 | macaca_mulatta | ENSMMUP00000063311 | 100 | 100 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 99.5349 | 99.0698 | macaca_mulatta | ENSMMUP00000038778 | 100 | 99.5327 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 100 | 100 | macaca_nemestrina | ENSMNEP00000008829 | 100 | 100 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 100 | 100 | papio_anubis | ENSPANP00000013674 | 100 | 100 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 100 | 100 | vulpes_vulpes | ENSVVUP00000013177 | 100 | 100 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 100 | 100 | equus_asinus | ENSEASP00005032782 | 100 | 100 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 100 | 99.5349 | capra_hircus | ENSCHIP00000019478 | 100 | 99.5349 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 100 | 100 | loxodonta_africana | ENSLAFP00000000221 | 100 | 100 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 99.0698 | 99.0698 | ailuropoda_melanoleuca | ENSAMEP00000036787 | 100 | 100 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 100 | 100 | oryctolagus_cuniculus | ENSOCUP00000022987 | 100 | 100 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 100 | 100 | canis_lupus_familiaris | ENSCAFP00845030356 | 100 | 100 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 100 | 99.5349 | panthera_pardus | ENSPPRP00000003291 | 100 | 99.5349 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 100 | 99.5349 | balaenoptera_musculus | ENSBMSP00010021324 | 100 | 99.5349 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 100 | 100 | cavia_porcellus | ENSCPOP00000023849 | 100 | 100 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 100 | 99.5349 | felis_catus | ENSFCAP00000058007 | 92.2747 | 91.8455 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 62.7907 | 60.4651 | ursus_americanus | ENSUAMP00000027615 | 90 | 86.6667 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 60.4651 | 56.2791 | ursus_americanus | ENSUAMP00000016646 | 77.8443 | 72.4551 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 100 | 99.5349 | bison_bison_bison | ENSBBBP00000019553 | 100 | 99.5349 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 100 | 99.5349 | monodon_monoceros | ENSMMNP00015027672 | 100 | 99.5349 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 84.6512 | 80.9302 | microcebus_murinus | ENSMICP00000039314 | 93.8144 | 89.6907 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 100 | 99.5349 | ovis_aries_rambouillet | ENSOARP00020011888 | 100 | 99.5349 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 61.3953 | 58.6047 | ursus_maritimus | ENSUMAP00000017563 | 86.8421 | 82.8947 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 74.8837 | 69.3023 | ursus_maritimus | ENSUMAP00000015582 | 80.5 | 74.5 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 91.6279 | 90.6977 | ochotona_princeps | ENSOPRP00000003207 | 92.4883 | 91.5493 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 100 | 99.5349 | physeter_catodon | ENSPCTP00005021097 | 100 | 99.5349 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 78.6047 | 76.7442 | mustela_putorius_furo | ENSMPUP00000004544 | 78.6047 | 76.7442 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 100 | 100 | aotus_nancymaae | ENSANAP00000032670 | 100 | 100 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 72.5581 | 71.6279 | vicugna_pacos | ENSVPAP00000004136 | 72.5581 | 71.6279 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 100 | 100 | chlorocebus_sabaeus | ENSCSAP00000018133 | 100 | 100 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 75.814 | 71.1628 | mesocricetus_auratus | ENSMAUP00000021851 | 74.4292 | 69.863 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 77.2093 | 70.6977 | mesocricetus_auratus | ENSMAUP00000014485 | 93.2584 | 85.3933 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 100 | 99.5349 | phocoena_sinus | ENSPSNP00000016365 | 100 | 99.5349 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 100 | 99.5349 | camelus_dromedarius | ENSCDRP00005007027 | 100 | 99.5349 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 84.186 | 82.7907 | carlito_syrichta | ENSTSYP00000011534 | 95.2632 | 93.6842 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 99.5349 | 99.0698 | panthera_tigris_altaica | ENSPTIP00000000717 | 99.5349 | 99.0698 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 100 | 100 | prolemur_simus | ENSPSMP00000025389 | 100 | 100 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 75.3488 | 73.9535 | microtus_ochrogaster | ENSMOCP00000012722 | 99.3865 | 97.546 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 86.9767 | 81.8605 | peromyscus_maniculatus_bairdii | ENSPEMP00000024305 | 90.7767 | 85.4369 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 76.2791 | 72.5581 | peromyscus_maniculatus_bairdii | ENSPEMP00000015278 | 88.172 | 83.871 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 100 | 99.5349 | bos_mutus | ENSBMUP00000030672 | 100 | 99.5349 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 100 | 99.0698 | mus_spicilegus | ENSMSIP00000027693 | 100 | 99.0698 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 100 | 98.1395 | myotis_lucifugus | ENSMLUP00000017918 | 100 | 98.1395 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 60.4651 | 55.3488 | vombatus_ursinus | ENSVURP00010027506 | 84.9673 | 77.7778 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 100 | 99.5349 | rhinolophus_ferrumequinum | ENSRFEP00010030289 | 100 | 99.5349 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 100 | 100 | rhinolophus_ferrumequinum | ENSRFEP00010000646 | 100 | 100 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 100 | 99.5349 | bos_taurus | ENSBTAP00000024094 | 100 | 99.5349 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 66.5116 | 60 | canis_lupus_dingo | ENSCAFP00020006515 | 80.791 | 72.8814 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 100 | 100 | sciurus_vulgaris | ENSSVLP00005005143 | 100 | 100 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 98.6047 | 95.814 | phascolarctos_cinereus | ENSPCIP00000028684 | 98.1481 | 95.3704 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 99.0698 | 98.6047 | procavia_capensis | ENSPCAP00000002051 | 99.5327 | 99.0654 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 100 | 100 | nannospalax_galili | ENSNGAP00000021602 | 100 | 100 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 100 | 99.5349 | chinchilla_lanigera | ENSCLAP00000004700 | 100 | 99.5349 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 100 | 99.5349 | catagonus_wagneri | ENSCWAP00000022716 | 100 | 99.5349 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 82.7907 | 79.5349 | ictidomys_tridecemlineatus | ENSSTOP00000028611 | 91.2821 | 87.6923 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 35.814 | 32.093 | otolemur_garnettii | ENSOGAP00000018872 | 62.0968 | 55.6452 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 85.1163 | 81.3953 | otolemur_garnettii | ENSOGAP00000017839 | 90.1478 | 86.2069 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 68.8372 | 65.5814 | otolemur_garnettii | ENSOGAP00000019196 | 84.5714 | 80.5714 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 63.7209 | 63.2558 | otolemur_garnettii | ENSOGAP00000009793 | 94.4828 | 93.7931 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 66.5116 | 63.7209 | urocitellus_parryii | ENSUPAP00010003445 | 89.9371 | 86.1635 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 26.5116 | 10.2326 | caenorhabditis_elegans | T20B12.8.1 | 8.17791 | 3.15638 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 25.5814 | 8.83721 | caenorhabditis_elegans | C32F10.5.1 | 7.98258 | 2.75762 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 38.1395 | 20 | ciona_intestinalis | ENSCINP00000023739 | 12.9134 | 6.77165 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 88.8372 | 75.3488 | latimeria_chalumnae | ENSLACP00000007563 | 88.4259 | 75 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 89.7674 | 80 | lepisosteus_oculatus | ENSLOCP00000000208 | 91.0377 | 81.1321 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 85.1163 | 72.093 | clupea_harengus | ENSCHAP00000028447 | 87.9808 | 74.5192 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 82.7907 | 67.907 | clupea_harengus | ENSCHAP00000035187 | 91.7526 | 75.2577 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 84.186 | 72.093 | danio_rerio | ENSDARP00000129778 | 91.8782 | 78.6802 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 87.4419 | 75.3488 | danio_rerio | ENSDARP00000134229 | 91.7073 | 79.0244 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 83.2558 | 71.6279 | carassius_auratus | ENSCARP00000038171 | 90.8629 | 78.1726 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 86.5116 | 76.2791 | carassius_auratus | ENSCARP00000045334 | 91.1765 | 80.3922 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 85.1163 | 73.9535 | carassius_auratus | ENSCARP00000062881 | 89.7059 | 77.9412 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 86.5116 | 76.2791 | carassius_auratus | ENSCARP00000072117 | 91.1765 | 80.3922 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 84.186 | 73.4884 | carassius_auratus | ENSCARP00000104241 | 89.604 | 78.2178 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 76.2791 | 67.907 | carassius_auratus | ENSCARP00000064377 | 83.2487 | 74.1117 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 82.7907 | 69.7674 | astyanax_mexicanus | ENSAMXP00000033973 | 89.899 | 75.7576 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 86.9767 | 74.8837 | astyanax_mexicanus | ENSAMXP00000052750 | 91.6667 | 78.9216 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 82.3256 | 67.4419 | ictalurus_punctatus | ENSIPUP00000018794 | 88.0597 | 72.1393 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 86.5116 | 74.8837 | ictalurus_punctatus | ENSIPUP00000028049 | 92.0792 | 79.703 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 83.7209 | 69.3023 | esox_lucius | ENSELUP00000030058 | 85.3081 | 70.6161 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 46.5116 | 37.2093 | esox_lucius | ENSELUP00000047932 | 78.125 | 62.5 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 82.7907 | 67.907 | esox_lucius | ENSELUP00000006284 | 39.821 | 32.6622 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 86.9767 | 74.8837 | electrophorus_electricus | ENSEEEP00000004772 | 89.4737 | 77.0335 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 83.2558 | 70.6977 | electrophorus_electricus | ENSEEEP00000044969 | 90.404 | 76.7677 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 78.6047 | 65.5814 | oncorhynchus_kisutch | ENSOKIP00005096492 | 87.5648 | 73.057 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 79.0698 | 65.5814 | oncorhynchus_kisutch | ENSOKIP00005017345 | 69.9588 | 58.0247 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 83.2558 | 69.7674 | oncorhynchus_kisutch | ENSOKIP00005097628 | 51.8841 | 43.4783 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 83.2558 | 70.6977 | oncorhynchus_kisutch | ENSOKIP00005052432 | 70.4724 | 59.8425 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 70.6977 | 53.0233 | oncorhynchus_mykiss | ENSOMYP00000115305 | 39.2765 | 29.4574 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 80 | 67.4419 | oncorhynchus_mykiss | ENSOMYP00000089595 | 88.6598 | 74.7423 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 78.6047 | 65.1163 | oncorhynchus_mykiss | ENSOMYP00000103750 | 87.5648 | 72.5389 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 83.7209 | 70.2326 | oncorhynchus_mykiss | ENSOMYP00000061042 | 88.2353 | 74.0196 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 83.2558 | 70.6977 | salmo_salar | ENSSSAP00000014193 | 51.8841 | 44.058 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 80.9302 | 67.4419 | salmo_salar | ENSSSAP00000124906 | 84.058 | 70.0483 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 80.9302 | 66.5116 | salmo_salar | ENSSSAP00000088894 | 84.8781 | 69.7561 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 68.8372 | 62.3256 | salmo_salar | ENSSSAP00000001492 | 92.5 | 83.75 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 80.4651 | 66.0465 | salmo_trutta | ENSSTUP00000054181 | 88.7179 | 72.8205 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 80.9302 | 67.4419 | salmo_trutta | ENSSTUP00000006268 | 88.7755 | 73.9796 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 83.2558 | 70.2326 | salmo_trutta | ENSSTUP00000081028 | 88.1773 | 74.3842 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 82.7907 | 70.2326 | salmo_trutta | ENSSTUP00000028590 | 87.6847 | 74.3842 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 81.8605 | 67.907 | gadus_morhua | ENSGMOP00000011409 | 87.1287 | 72.2772 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 85.5814 | 71.6279 | gadus_morhua | ENSGMOP00000061317 | 76.0331 | 63.6364 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 86.5116 | 75.3488 | fundulus_heteroclitus | ENSFHEP00000000507 | 92.0792 | 80.198 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 82.3256 | 73.0233 | fundulus_heteroclitus | ENSFHEP00000010586 | 89.3939 | 79.2929 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 85.1163 | 71.6279 | poecilia_reticulata | ENSPREP00000015404 | 91.5 | 77 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 82.3256 | 72.093 | poecilia_reticulata | ENSPREP00000017770 | 88.9447 | 77.8895 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 82.3256 | 72.093 | xiphophorus_maculatus | ENSXMAP00000008429 | 88.5 | 77.5 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 85.5814 | 72.093 | xiphophorus_maculatus | ENSXMAP00000031756 | 92 | 77.5 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 81.8605 | 72.5581 | oryzias_latipes | ENSORLP00000004935 | 90.7216 | 80.4124 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 85.5814 | 72.093 | oryzias_latipes | ENSORLP00000004224 | 89.3204 | 75.2427 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 82.7907 | 68.8372 | cyclopterus_lumpus | ENSCLMP00005024170 | 82.0276 | 68.2028 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 81.3953 | 66.0465 | cyclopterus_lumpus | ENSCLMP00005016841 | 84.9515 | 68.932 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 86.9767 | 75.3488 | oreochromis_niloticus | ENSONIP00000015992 | 89.4737 | 77.512 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 84.186 | 73.4884 | oreochromis_niloticus | ENSONIP00000006916 | 89.604 | 78.2178 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 73.4884 | 66.9767 | haplochromis_burtoni | ENSHBUP00000024529 | 78.607 | 71.6418 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 73.0233 | 64.6512 | haplochromis_burtoni | ENSHBUP00000022355 | 59.2453 | 52.4528 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 86.9767 | 74.8837 | astatotilapia_calliptera | ENSACLP00000006405 | 90.7767 | 78.1553 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 84.186 | 73.4884 | astatotilapia_calliptera | ENSACLP00000000854 | 89.1626 | 77.8325 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 83.7209 | 68.8372 | sparus_aurata | ENSSAUP00010061584 | 87.3786 | 71.8447 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 85.5814 | 71.6279 | sparus_aurata | ENSSAUP00010057079 | 92 | 77 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 86.9767 | 75.814 | lates_calcarifer | ENSLCAP00010051443 | 87.3832 | 76.1682 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 84.186 | 73.4884 | lates_calcarifer | ENSLCAP00010029190 | 90.5 | 79 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 93.4884 | 85.1163 | xenopus_tropicalis | ENSXETP00000041556 | 95.2607 | 86.7299 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 97.2093 | 90.6977 | chrysemys_picta_bellii | ENSCPBP00000028965 | 83.2669 | 77.6892 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 97.2093 | 90.2326 | sphenodon_punctatus | ENSSPUP00000005787 | 97.2093 | 90.2326 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 96.7442 | 92.093 | crocodylus_porosus | ENSCPRP00005016847 | 96.7442 | 92.093 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 96.7442 | 87.4419 | laticauda_laticaudata | ENSLLTP00000014976 | 96.7442 | 87.4419 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 96.2791 | 86.5116 | notechis_scutatus | ENSNSUP00000017527 | 96.2791 | 86.5116 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 96.7442 | 87.4419 | pseudonaja_textilis | ENSPTXP00000007362 | 96.7442 | 87.4419 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 97.2093 | 88.8372 | anas_platyrhynchos_platyrhynchos | ENSAPLP00000023852 | 74.3772 | 67.9715 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 97.2093 | 90.6977 | gallus_gallus | ENSGALP00010009411 | 83.9357 | 78.3133 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 97.2093 | 90.6977 | meleagris_gallopavo | ENSMGAP00000016001 | 86.3636 | 80.5785 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 96.7442 | 89.3023 | serinus_canaria | ENSSCAP00000008814 | 96.7442 | 89.3023 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 96.7442 | 88.8372 | parus_major | ENSPMJP00000023656 | 96.7442 | 88.8372 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 95.3488 | 88.8372 | anolis_carolinensis | ENSACAP00000004985 | 96.2441 | 89.6714 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 73.4884 | 65.1163 | neolamprologus_brichardi | ENSNBRP00000031107 | 60.076 | 53.2319 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 86.9767 | 74.8837 | neolamprologus_brichardi | ENSNBRP00000018444 | 90.7767 | 78.1553 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 96.7442 | 87.4419 | naja_naja | ENSNNAP00000028396 | 96.7442 | 87.4419 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 97.2093 | 86.5116 | podarcis_muralis | ENSPMRP00000006335 | 94.1441 | 83.7838 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 96.7442 | 89.3023 | geospiza_fortis | ENSGFOP00000022301 | 91.63 | 84.5815 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 96.7442 | 89.3023 | taeniopygia_guttata | ENSTGUP00000018547 | 96.7442 | 89.3023 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 91.1628 | 80.4651 | erpetoichthys_calabaricus | ENSECRP00000006210 | 92.891 | 81.9905 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 84.186 | 73.4884 | kryptolebias_marmoratus | ENSKMAP00000010952 | 91.4141 | 79.798 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 86.9767 | 75.3488 | kryptolebias_marmoratus | ENSKMAP00000008766 | 90.7767 | 78.6408 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 35.814 | 29.3023 | salvator_merianae | ENSSMRP00000017860 | 56.6176 | 46.3235 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 84.6512 | 72.093 | oryzias_javanicus | ENSOJAP00000042981 | 87.0813 | 74.1627 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 82.7907 | 72.5581 | oryzias_javanicus | ENSOJAP00000020190 | 90.8163 | 79.5918 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 86.0465 | 75.3488 | amphilophus_citrinellus | ENSACIP00000030617 | 89.372 | 78.2609 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 84.186 | 72.5581 | amphilophus_citrinellus | ENSACIP00000005864 | 90.9548 | 78.392 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 85.1163 | 70.6977 | dicentrarchus_labrax | ENSDLAP00005067559 | 88.835 | 73.7864 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 84.186 | 70.6977 | dicentrarchus_labrax | ENSDLAP00005032199 | 90.0498 | 75.6219 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 71.1628 | 62.3256 | amphiprion_percula | ENSAPEP00000013186 | 64.0167 | 56.0669 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 86.9767 | 73.0233 | amphiprion_percula | ENSAPEP00000027180 | 90.7767 | 76.2136 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 86.0465 | 73.0233 | oryzias_sinensis | ENSOSIP00000041004 | 89.8058 | 76.2136 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 69.7674 | 63.2558 | oryzias_sinensis | ENSOSIP00000011584 | 83.7989 | 75.9777 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 96.7442 | 92.093 | pelodiscus_sinensis | ENSPSIP00000008123 | 96.7442 | 92.093 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 97.2093 | 91.6279 | gopherus_evgoodei | ENSGEVP00005001972 | 97.2093 | 91.6279 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 97.2093 | 91.6279 | chelonoidis_abingdonii | ENSCABP00000010796 | 97.2093 | 91.6279 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 84.6512 | 73.4884 | seriola_dumerili | ENSSDUP00000015193 | 91.4573 | 79.397 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 87.907 | 75.3488 | seriola_dumerili | ENSSDUP00000020653 | 91.7476 | 78.6408 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 83.7209 | 68.3721 | cottoperca_gobio | ENSCGOP00000003097 | 86.9565 | 71.0145 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 81.3953 | 65.1163 | cottoperca_gobio | ENSCGOP00000019956 | 85.7843 | 68.6274 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 96.7442 | 88.8372 | struthio_camelus_australis | ENSSCUP00000020207 | 77.3234 | 71.0037 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 97.2093 | 89.7674 | anser_brachyrhynchus | ENSABRP00000023855 | 97.2093 | 89.7674 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 78.6047 | 66.9767 | gasterosteus_aculeatus | ENSGACP00000027163 | 77.8802 | 66.3594 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 81.8605 | 67.4419 | gasterosteus_aculeatus | ENSGACP00000015140 | 89.7959 | 73.9796 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 83.2558 | 72.093 | cynoglossus_semilaevis | ENSCSEP00000011604 | 86.4734 | 74.8792 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 84.6512 | 70.6977 | cynoglossus_semilaevis | ENSCSEP00000019774 | 88.7805 | 74.1463 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 84.6512 | 71.6279 | poecilia_formosa | ENSPFOP00000012542 | 91 | 77 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 81.3953 | 71.1628 | poecilia_formosa | ENSPFOP00000004380 | 88.8325 | 77.665 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 84.186 | 72.093 | myripristis_murdjan | ENSMMDP00005013010 | 90.9548 | 77.8895 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 80.9302 | 65.1163 | sander_lucioperca | ENSSLUP00000024218 | 87.4372 | 70.3518 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 81.8605 | 67.4419 | sander_lucioperca | ENSSLUP00000020922 | 84.6154 | 69.7115 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 97.2093 | 89.7674 | strigops_habroptila | ENSSHBP00005018260 | 97.2093 | 89.7674 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 86.9767 | 73.0233 | amphiprion_ocellaris | ENSAOCP00000005295 | 90.7767 | 76.2136 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 84.6512 | 72.093 | amphiprion_ocellaris | ENSAOCP00000005338 | 91 | 77.5 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 97.2093 | 90.6977 | terrapene_carolina_triunguis | ENSTMTP00000008927 | 97.2093 | 90.6977 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 97.2093 | 90.6977 | terrapene_carolina_triunguis | ENSTMTP00000023669 | 97.2093 | 90.6977 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 27.4419 | 22.7907 | hucho_hucho | ENSHHUP00000005738 | 92.1875 | 76.5625 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 82.7907 | 70.2326 | hucho_hucho | ENSHHUP00000014507 | 53.2934 | 45.2096 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 80.4651 | 66.9767 | hucho_hucho | ENSHHUP00000069710 | 65.7795 | 54.7529 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 80.4651 | 65.5814 | hucho_hucho | ENSHHUP00000062456 | 85.2217 | 69.4581 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 84.186 | 71.6279 | betta_splendens | ENSBSLP00000026398 | 92.3469 | 78.5714 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 86.9767 | 75.3488 | betta_splendens | ENSBSLP00000013579 | 91.2195 | 79.0244 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 83.2558 | 69.3023 | pygocentrus_nattereri | ENSPNAP00000024386 | 90.404 | 75.2525 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 87.4419 | 74.8837 | pygocentrus_nattereri | ENSPNAP00000005012 | 89.9522 | 77.0335 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 86.9767 | 76.2791 | anabas_testudineus | ENSATEP00000006460 | 91.2195 | 80 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 84.186 | 73.0233 | anabas_testudineus | ENSATEP00000067404 | 90.9548 | 78.8945 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 38.1395 | 22.3256 | ciona_savignyi | ENSCSAVP00000015780 | 13.3768 | 7.83034 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 84.6512 | 73.4884 | seriola_lalandi_dorsalis | ENSSLDP00000006086 | 91.4573 | 79.397 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 87.4419 | 75.3488 | seriola_lalandi_dorsalis | ENSSLDP00000029005 | 91.2621 | 78.6408 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 84.186 | 70.2326 | labrus_bergylta | ENSLBEP00000003372 | 88.2927 | 73.6585 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 80.4651 | 67.4419 | labrus_bergylta | ENSLBEP00000002242 | 84.8039 | 71.0784 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 84.186 | 73.4884 | pundamilia_nyererei | ENSPNYP00000015825 | 90.0498 | 78.607 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 86.5116 | 74.8837 | pundamilia_nyererei | ENSPNYP00000018860 | 90.2913 | 78.1553 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 85.5814 | 73.9535 | mastacembelus_armatus | ENSMAMP00000050050 | 92 | 79.5 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 86.5116 | 74.8837 | mastacembelus_armatus | ENSMAMP00000022491 | 89.8551 | 77.7778 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 85.1163 | 73.4884 | stegastes_partitus | ENSSPAP00000018146 | 73.494 | 63.4538 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 87.4419 | 73.9535 | stegastes_partitus | ENSSPAP00000015265 | 91.2621 | 77.1845 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 69.7674 | 62.3256 | oncorhynchus_tshawytscha | ENSOTSP00005040525 | 57.2519 | 51.145 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 78.6047 | 65.5814 | oncorhynchus_tshawytscha | ENSOTSP00005030988 | 87.5648 | 73.057 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 79.5349 | 66.5116 | oncorhynchus_tshawytscha | ENSOTSP00005070085 | 76.3393 | 63.8393 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 83.2558 | 69.7674 | oncorhynchus_tshawytscha | ENSOTSP00005049906 | 51.8841 | 43.4783 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 85.1163 | 72.5581 | acanthochromis_polyacanthus | ENSAPOP00000003212 | 91.5 | 78 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 86.9767 | 73.0233 | acanthochromis_polyacanthus | ENSAPOP00000031668 | 90.7767 | 76.2136 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 97.2093 | 89.7674 | aquila_chrysaetos_chrysaetos | ENSACCP00020022589 | 97.2093 | 89.7674 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 82.7907 | 71.1628 | nothobranchius_furzeri | ENSNFUP00015005587 | 79.1111 | 68 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 84.186 | 71.6279 | nothobranchius_furzeri | ENSNFUP00015028136 | 88.7255 | 75.4902 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 83.7209 | 72.093 | cyprinodon_variegatus | ENSCVAP00000010421 | 90.4523 | 77.8895 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 85.1163 | 74.8837 | cyprinodon_variegatus | ENSCVAP00000011438 | 91.0448 | 80.0995 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 87.4419 | 75.3488 | denticeps_clupeoides | ENSDCDP00000058832 | 68.8645 | 59.3407 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 84.6512 | 73.4884 | denticeps_clupeoides | ENSDCDP00000053783 | 93.8144 | 81.4433 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 73.4884 | 64.186 | larimichthys_crocea | ENSLCRP00005019539 | 72.8111 | 63.5945 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 84.6512 | 70.2326 | larimichthys_crocea | ENSLCRP00005053152 | 88.3495 | 73.301 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 82.3256 | 71.1628 | takifugu_rubripes | ENSTRUP00000011525 | 90.3061 | 78.0612 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 83.7209 | 69.3023 | takifugu_rubripes | ENSTRUP00000050342 | 67.9245 | 56.2264 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 82.7907 | 68.8372 | takifugu_rubripes | ENSTRUP00000063649 | 67.6806 | 56.2738 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 96.7442 | 89.3023 | ficedula_albicollis | ENSFALP00000031397 | 81.5686 | 75.2941 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 86.0465 | 73.0233 | hippocampus_comes | ENSHCOP00000023700 | 88.9423 | 75.4808 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 83.2558 | 72.5581 | hippocampus_comes | ENSHCOP00000008722 | 89.0547 | 77.6119 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 87.4419 | 75.814 | cyprinus_carpio_carpio | ENSCCRP00000101002 | 91.2621 | 79.1262 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 83.2558 | 72.093 | cyprinus_carpio_carpio | ENSCCRP00000112487 | 90.8629 | 78.6802 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 83.7209 | 70.2326 | cyprinus_carpio_carpio | ENSCCRP00000105541 | 80.3571 | 67.4107 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 25.5814 | 21.8605 | cyprinus_carpio_carpio | ENSCCRP00000179116 | 80.8824 | 69.1176 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 82.3256 | 76.2791 | coturnix_japonica | ENSCJPP00005026184 | 80.0905 | 74.2081 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 85.1163 | 72.093 | poecilia_latipinna | ENSPLAP00000006377 | 91.9598 | 77.8895 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 80.9302 | 70.2326 | poecilia_latipinna | ENSPLAP00000015365 | 88.7755 | 77.0408 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 85.5814 | 74.4186 | sinocyclocheilus_grahami | ENSSGRP00000047344 | 90.6404 | 78.8177 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 82.7907 | 69.3023 | sinocyclocheilus_grahami | ENSSGRP00000035062 | 88.5572 | 74.1294 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 86.0465 | 76.2791 | sinocyclocheilus_grahami | ENSSGRP00000035854 | 91.133 | 80.7882 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 71.1628 | 63.2558 | sinocyclocheilus_grahami | ENSSGRP00000072130 | 72.1698 | 64.1509 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 84.186 | 73.4884 | maylandia_zebra | ENSMZEP00005014720 | 90.0498 | 78.607 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 86.9767 | 74.8837 | maylandia_zebra | ENSMZEP00005032992 | 90.7767 | 78.1553 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 84.186 | 69.3023 | tetraodon_nigroviridis | ENSTNIP00000012801 | 85.782 | 70.6161 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 79.0698 | 69.7674 | tetraodon_nigroviridis | ENSTNIP00000019352 | 82.1256 | 72.4638 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 89.7674 | 76.7442 | paramormyrops_kingsleyae | ENSPKIP00000037978 | 79.7521 | 68.1818 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 89.3023 | 75.3488 | scleropages_formosus | ENSSFOP00015007048 | 89.3023 | 75.3488 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 79.0698 | 68.8372 | leptobrachium_leishanense | ENSLLEP00000014386 | 49.5627 | 43.1487 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 88.3721 | 79.5349 | leptobrachium_leishanense | ENSLLEP00000034182 | 46.798 | 42.1182 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 86.5116 | 71.6279 | scophthalmus_maximus | ENSSMAP00000006577 | 91.1765 | 75.4902 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 81.8605 | 69.3023 | scophthalmus_maximus | ENSSMAP00000009812 | 88.4422 | 74.8744 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 82.3256 | 72.093 | oryzias_melastigma | ENSOMEP00000022835 | 90.7692 | 79.4872 |
| ENSG00000189403 | homo_sapiens | ENSP00000345347 | 86.5116 | 74.8837 | oryzias_melastigma | ENSOMEP00000028478 | 74.6988 | 64.6586 |
Gene Ontology
| Go ID | Go term | No. evidence | Entries | Species | Category |
|---|---|---|---|---|---|
| GO:0000122 | involved_in negative regulation of transcription by RNA polymerase II | 3 | IDA,IGI,IMP | Homo_sapiens(9606) | Process |
| GO:0000400 | enables four-way junction DNA binding | 1 | ISS | Homo_sapiens(9606) | Function |
| GO:0000405 | enables bubble DNA binding | 1 | ISS | Homo_sapiens(9606) | Function |
| GO:0000793 | located_in condensed chromosome | 1 | IDA | Homo_sapiens(9606) | Component |
| GO:0000976 | enables transcription cis-regulatory region binding | 1 | IDA | Homo_sapiens(9606) | Function |
| GO:0001530 | enables lipopolysaccharide binding | 1 | IDA | Homo_sapiens(9606) | Function |
| GO:0001773 | involved_in myeloid dendritic cell activation | 1 | ISS | Homo_sapiens(9606) | Process |
| GO:0001786 | enables phosphatidylserine binding | 1 | IDA | Homo_sapiens(9606) | Function |
| GO:0002218 | involved_in activation of innate immune response | 1 | IDA | Homo_sapiens(9606) | Process |
| GO:0002407 | involved_in dendritic cell chemotaxis | 1 | ISS | Homo_sapiens(9606) | Process |
| GO:0002437 | involved_in inflammatory response to antigenic stimulus | 1 | IEP | Homo_sapiens(9606) | Process |
| GO:0002643 | involved_in regulation of tolerance induction | 1 | IDA | Homo_sapiens(9606) | Process |
| GO:0002840 | involved_in regulation of T cell mediated immune response to tumor cell | 1 | ISS | Homo_sapiens(9606) | Process |
| GO:0003684 | enables damaged DNA binding | 2 | IDA,ISS | Homo_sapiens(9606) | Function |
| GO:0003690 | enables double-stranded DNA binding | 1 | ISS | Homo_sapiens(9606) | Function |
| GO:0003697 | enables single-stranded DNA binding | 1 | ISS | Homo_sapiens(9606) | Function |
| GO:0003713 | enables transcription coactivator activity | 1 | IDA | Homo_sapiens(9606) | Function |
| GO:0003714 | enables transcription corepressor activity | 1 | IDA | Homo_sapiens(9606) | Function |
| GO:0003723 | enables RNA binding | 1 | HDA | Homo_sapiens(9606) | Function |
| GO:0005125 | enables cytokine activity | 1 | ISS | Homo_sapiens(9606) | Function |
| GO:0005178 | enables integrin binding | 1 | IDA | Homo_sapiens(9606) | Function |
| GO:0005515 | enables protein binding | 1 | IPI | Homo_sapiens(9606) | Function |
| GO:0005576 | located_in extracellular region | 1 | TAS | Homo_sapiens(9606) | Component |
| GO:0005615 | is_active_in extracellular space | 3 | IDA,ISS | Homo_sapiens(9606) | Component |
| GO:0005634 | located_in nucleus | 2 | IDA,ISS | Homo_sapiens(9606) | Component |
| GO:0005654 | located_in nucleoplasm | 1 | TAS | Homo_sapiens(9606) | Component |
| GO:0005768 | located_in endosome | 1 | IEA | Homo_sapiens(9606) | Component |
| GO:0005783 | located_in endoplasmic reticulum | 1 | IDA | Homo_sapiens(9606) | Component |
| GO:0005793 | located_in endoplasmic reticulum-Golgi intermediate compartment | 1 | IEA | Homo_sapiens(9606) | Component |
| GO:0006265 | involved_in DNA topological change | 1 | ISS | Homo_sapiens(9606) | Process |
| GO:0006303 | involved_in double-strand break repair via nonhomologous end joining | 1 | ISS | Homo_sapiens(9606) | Process |
| GO:0006310 | involved_in DNA recombination | 1 | ISS | Homo_sapiens(9606) | Process |
| GO:0006357 | involved_in regulation of transcription by RNA polymerase II | 1 | IBA | Homo_sapiens(9606) | Process |
| GO:0006914 | involved_in autophagy | 1 | IEA | Homo_sapiens(9606) | Process |
| GO:0006954 | involved_in inflammatory response | 1 | IDA | Homo_sapiens(9606) | Process |
| GO:0007165 | involved_in signal transduction | 1 | IEA | Homo_sapiens(9606) | Process |
| GO:0007204 | involved_in positive regulation of cytosolic calcium ion concentration | 1 | IDA | Homo_sapiens(9606) | Process |
| GO:0008301 | enables DNA binding, bending | 3 | IBA,IMP,ISS | Homo_sapiens(9606) | Function |
| GO:0009986 | located_in cell surface | 1 | IDA | Homo_sapiens(9606) | Component |
| GO:0010508 | involved_in positive regulation of autophagy | 1 | IMP | Homo_sapiens(9606) | Process |
| GO:0016829 | enables lyase activity | 1 | IDA | Homo_sapiens(9606) | Function |
| GO:0017053 | part_of transcription repressor complex | 1 | IDA | Homo_sapiens(9606) | Component |
| GO:0017055 | involved_in negative regulation of RNA polymerase II transcription preinitiation complex assembly | 1 | IDA | Homo_sapiens(9606) | Process |
| GO:0019958 | enables C-X-C chemokine binding | 1 | IDA | Homo_sapiens(9606) | Function |
| GO:0031175 | involved_in neuron projection development | 1 | ISS | Homo_sapiens(9606) | Process |
| GO:0031507 | involved_in heterochromatin formation | 1 | IGI | Homo_sapiens(9606) | Process |
| GO:0032072 | involved_in regulation of restriction endodeoxyribonuclease activity | 1 | IDA | Homo_sapiens(9606) | Process |
| GO:0032392 | involved_in DNA geometric change | 1 | ISS | Homo_sapiens(9606) | Process |
| GO:0032425 | involved_in positive regulation of mismatch repair | 1 | IDA | Homo_sapiens(9606) | Process |
| GO:0032689 | involved_in negative regulation of type II interferon production | 1 | IDA | Homo_sapiens(9606) | Process |
| GO:0032732 | involved_in positive regulation of interleukin-1 production | 1 | IDA | Homo_sapiens(9606) | Process |
| GO:0032733 | involved_in positive regulation of interleukin-10 production | 1 | IDA | Homo_sapiens(9606) | Process |
| GO:0032735 | involved_in positive regulation of interleukin-12 production | 1 | IMP | Homo_sapiens(9606) | Process |
| GO:0032755 | involved_in positive regulation of interleukin-6 production | 1 | IDA | Homo_sapiens(9606) | Process |
| GO:0032757 | involved_in positive regulation of interleukin-8 production | 1 | IDA | Homo_sapiens(9606) | Process |
| GO:0032760 | involved_in positive regulation of tumor necrosis factor production | 1 | IDA | Homo_sapiens(9606) | Process |
| GO:0033151 | involved_in V(D)J recombination | 1 | IDA | Homo_sapiens(9606) | Process |
| GO:0034165 | involved_in positive regulation of toll-like receptor 9 signaling pathway | 1 | ISS | Homo_sapiens(9606) | Process |
| GO:0034774 | located_in secretory granule lumen | 1 | TAS | Homo_sapiens(9606) | Component |
| GO:0035711 | involved_in T-helper 1 cell activation | 1 | IDA | Homo_sapiens(9606) | Process |
| GO:0035868 | part_of alphav-beta3 integrin-HMGB1 complex | 1 | IDA | Homo_sapiens(9606) | Component |
| GO:0042056 | enables chemoattractant activity | 1 | ISS | Homo_sapiens(9606) | Function |
| GO:0042104 | involved_in positive regulation of activated T cell proliferation | 1 | IMP | Homo_sapiens(9606) | Process |
| GO:0043065 | involved_in positive regulation of apoptotic process | 1 | IDA | Homo_sapiens(9606) | Process |
| GO:0043277 | involved_in apoptotic cell clearance | 1 | IDA | Homo_sapiens(9606) | Process |
| GO:0043280 | involved_in positive regulation of cysteine-type endopeptidase activity involved in apoptotic process | 1 | IDA | Homo_sapiens(9606) | Process |
| GO:0043371 | involved_in negative regulation of CD4-positive, alpha-beta T cell differentiation | 1 | IDA | Homo_sapiens(9606) | Process |
| GO:0043388 | involved_in positive regulation of DNA binding | 1 | IDA | Homo_sapiens(9606) | Process |
| GO:0043410 | involved_in positive regulation of MAPK cascade | 1 | IDA | Homo_sapiens(9606) | Process |
| GO:0043536 | involved_in positive regulation of blood vessel endothelial cell migration | 1 | IMP | Homo_sapiens(9606) | Process |
| GO:0043537 | involved_in negative regulation of blood vessel endothelial cell migration | 1 | IDA | Homo_sapiens(9606) | Process |
| GO:0045063 | involved_in T-helper 1 cell differentiation | 1 | IMP | Homo_sapiens(9606) | Process |
| GO:0045087 | involved_in innate immune response | 1 | IEA | Homo_sapiens(9606) | Process |
| GO:0045944 | involved_in positive regulation of transcription by RNA polymerase II | 1 | IDA | Homo_sapiens(9606) | Process |
| GO:0046330 | involved_in positive regulation of JNK cascade | 1 | IDA | Homo_sapiens(9606) | Process |
| GO:0046598 | involved_in positive regulation of viral entry into host cell | 1 | IMP | Homo_sapiens(9606) | Process |
| GO:0048018 | enables receptor ligand activity | 1 | IDA | Homo_sapiens(9606) | Function |
| GO:0050786 | enables RAGE receptor binding | 1 | ISS | Homo_sapiens(9606) | Function |
| GO:0050918 | involved_in positive chemotaxis | 1 | IEA | Homo_sapiens(9606) | Process |
| GO:0051106 | involved_in positive regulation of DNA ligation | 1 | ISS | Homo_sapiens(9606) | Process |
| GO:0061629 | enables RNA polymerase II-specific DNA-binding transcription factor binding | 1 | IPI | Homo_sapiens(9606) | Function |
| GO:0070182 | enables DNA polymerase binding | 1 | IDA | Homo_sapiens(9606) | Function |
| GO:0070374 | involved_in positive regulation of ERK1 and ERK2 cascade | 1 | IDA | Homo_sapiens(9606) | Process |
| GO:0071222 | involved_in cellular response to lipopolysaccharide | 1 | ISS | Homo_sapiens(9606) | Process |
| GO:0090026 | involved_in positive regulation of monocyte chemotaxis | 1 | IDA | Homo_sapiens(9606) | Process |
| GO:0097100 | enables supercoiled DNA binding | 1 | ISS | Homo_sapiens(9606) | Function |
| GO:0097350 | involved_in neutrophil clearance | 1 | IDA | Homo_sapiens(9606) | Process |
| GO:0140297 | enables DNA-binding transcription factor binding | 1 | IPI | Homo_sapiens(9606) | Function |
| GO:1904813 | located_in ficolin-1-rich granule lumen | 1 | TAS | Homo_sapiens(9606) | Component |
| GO:1905564 | involved_in positive regulation of vascular endothelial cell proliferation | 1 | IMP | Homo_sapiens(9606) | Process |
| GO:2000343 | involved_in positive regulation of chemokine (C-X-C motif) ligand 2 production | 1 | IDA | Homo_sapiens(9606) | Process |
| GO:2000426 | involved_in negative regulation of apoptotic cell clearance | 1 | IDA | Homo_sapiens(9606) | Process |
| GO:2001200 | involved_in positive regulation of dendritic cell differentiation | 1 | IMP | Homo_sapiens(9606) | Process |