RBP Type
Canonical_RBPs
Diseases
Drug
N.A.
Main interacting RNAs
N.A.
Moonlighting functions
TF
Localizations
N.A.
BulkPerturb-seq
N.A.
Ensembl ID ENSG00000189298 Gene ID
80317 Accession
13853
Symbol
ZKSCAN3
Alias
ZF47;Zfp47;ZFP306;ZNF306;ZNF309;zfp-47;ZSCAN13;ZSCAN35;dJ874C20.1;dJ874C20.1.
Full Name
zinc finger with KRAB and SCAN domains 3
Status
Confidence
Length
19226 bases
Strand
Plus strand
Position
6 : 28349947 - 28369172
RNA binding domain
zf-met
Summary
Enables DNA-binding transcription repressor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and chromatin binding activity. Involved in several processes, including negative regulation of autophagy; negative regulation of cellular senescence; and regulation of transcription, DNA-templated. Located in cytoplasm and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]
RNA binding domains (RBDs)
Protein
Domain
Pfam ID
E-value
Domain number
ENSP00000341883
zf-met
PF12874 7.5e-05
1
ENSP00000252211
zf-met
PF12874 0.0011
1
ENSP00000366465
zf-met
PF12874 0.0011
1
RNA binding proteomes (RBPomes)
Pubmed ID
Full Name
Cell
Author
Time
Doi
Literatures on RNA binding capacity
Pubmed ID
Title
Author
Time
Journal
Name
Transcript ID
bp
Protein
Translation ID
Pathway ID
Pathway Name
Source
ensgID
Trait
pValue
Pubmed ID
17897 Body Height 3.737e-005 18193045 35620 Platelet Function Tests 4.0341100E-005 - 51745 Autistic Disorder 4.5550000E-005 - 51746 Autistic Disorder 2.7384000E-005 - 95292 Forced Expiratory Volume 2E-10 21946350 95293 Respiratory Function Tests 2E-10 21946350
ensgID SNP Chromosome Position
Trait PubmedID Or or BEAT
EFO ID
Protein-Protein Interaction (PPI)
Ensembl ID
Source
Target
Species
Protein ID
Perc_pos
Perc_id
Species
Protein ID
Perc_pos
Perc_id
ENSG00000189298 homo_sapiens ENSP00000507525 57.1134 40.8247 homo_sapiens ENSP00000252211 51.487 36.803 ENSG00000189298 homo_sapiens ENSP00000506997 21.0136 14.3387 homo_sapiens ENSP00000252211 31.5985 21.5613 ENSG00000189298 homo_sapiens ENSP00000219091 35.7401 24.0072 homo_sapiens ENSP00000252211 36.803 24.7212 ENSG00000189298 homo_sapiens ENSP00000292450 60.6765 45.666 homo_sapiens ENSP00000252211 53.3457 40.1487 ENSG00000189298 homo_sapiens ENSP00000261332 63.587 45.6522 homo_sapiens ENSP00000252211 43.4944 31.2268 ENSG00000189298 homo_sapiens ENSP00000507347 45.4992 35.3519 homo_sapiens ENSP00000252211 51.6729 40.1487 ENSG00000189298 homo_sapiens ENSP00000359802 40.7843 28.0392 homo_sapiens ENSP00000252211 38.6617 26.5799 ENSG00000189298 homo_sapiens ENSP00000499415 39.1061 26.8156 homo_sapiens ENSP00000252211 39.0335 26.7658 ENSG00000189298 homo_sapiens ENSP00000377708 43.1985 31.9853 homo_sapiens ENSP00000252211 43.6803 32.342 ENSG00000189298 homo_sapiens ENSP00000321963 38.3372 23.7875 homo_sapiens ENSP00000252211 30.855 19.145 ENSG00000189298 homo_sapiens ENSP00000252207 59.6447 45.1777 homo_sapiens ENSP00000252211 43.6803 33.0855 ENSG00000189298 homo_sapiens ENSP00000380087 50.9804 36.1656 homo_sapiens ENSP00000252211 43.4944 30.855 ENSG00000189298 homo_sapiens ENSP00000455585 28.9833 19.1199 homo_sapiens ENSP00000252211 35.5019 23.4201 ENSG00000189298 homo_sapiens ENSP00000331577 52.6217 41.3858 homo_sapiens ENSP00000252211 52.2305 41.0781 ENSG00000189298 homo_sapiens ENSP00000289788 62.982 47.5578 homo_sapiens ENSP00000252211 45.539 34.3866 ENSG00000189298 homo_sapiens ENSP00000337363 47.2371 33.8681 homo_sapiens ENSP00000252211 49.2565 35.316 ENSG00000189298 homo_sapiens ENSP00000345339 66.7488 50.2463 homo_sapiens ENSP00000252211 50.3717 37.9182 ENSG00000189298 homo_sapiens ENSP00000515300 44.4109 32.0242 homo_sapiens ENSP00000252211 27.3234 19.7026 ENSG00000189298 homo_sapiens ENSP00000219069 45.0952 31.918 homo_sapiens ENSP00000252211 57.2491 40.5204 ENSG00000189298 homo_sapiens ENSP00000339585 43.6293 32.4324 homo_sapiens ENSP00000252211 42.0074 31.2268 ENSG00000189298 homo_sapiens ENSP00000332433 50.9165 38.9002 homo_sapiens ENSP00000252211 46.4684 35.5019 ENSG00000189298 homo_sapiens ENSP00000329738 57.6923 43.5223 homo_sapiens ENSP00000252211 52.974 39.9628 ENSG00000189298 homo_sapiens ENSP00000466500 60.8955 42.6866 homo_sapiens ENSP00000252211 37.9182 26.5799 ENSG00000189298 homo_sapiens ENSP00000219478 40 32.9167 homo_sapiens ENSP00000252211 35.6877 29.368 ENSG00000189298 homo_sapiens ENSP00000366509 88.0734 84.2202 homo_sapiens ENSP00000252211 89.2193 85.316 ENSG00000189298 homo_sapiens ENSP00000278319 35.2031 23.7911 homo_sapiens ENSP00000252211 33.829 22.8625 ENSG00000189298 homo_sapiens ENSP00000366527 64.6552 50.8621 homo_sapiens ENSP00000252211 41.8216 32.8996 ENSG00000189298 homo_sapiens ENSP00000323148 52.0426 38.7211 homo_sapiens ENSP00000252211 54.461 40.5204 ENSG00000189298 homo_sapiens ENSP00000481707 52.1921 39.2484 homo_sapiens ENSP00000252211 46.4684 34.9442 ENSG00000189298 homo_sapiens ENSP00000332750 54.6713 41.5225 homo_sapiens ENSP00000252211 58.7361 44.6097 ENSG00000189298 homo_sapiens ENSP00000250076 48.6486 35.3604 homo_sapiens ENSP00000252211 40.1487 29.1822
Ensembl ID
Source
Target
Species
Protein ID
Perc_pos
Perc_id
Species
Protein ID
Perc_pos
Perc_id
ENSG00000189298 homo_sapiens ENSP00000252211 99.2565 98.1413 nomascus_leucogenys ENSNLEP00000005536 99.2565 98.1413 ENSG00000189298 homo_sapiens ENSP00000252211 99.6283 99.2565 pan_paniscus ENSPPAP00000031082 99.6283 99.2565 ENSG00000189298 homo_sapiens ENSP00000252211 99.0706 98.3271 pongo_abelii ENSPPYP00000018301 99.0706 98.3271 ENSG00000189298 homo_sapiens ENSP00000252211 99.6283 99.0706 pan_troglodytes ENSPTRP00000086687 99.6283 99.0706 ENSG00000189298 homo_sapiens ENSP00000252211 99.8141 99.4424 gorilla_gorilla ENSGGOP00000009264 99.8141 99.4424 ENSG00000189298 homo_sapiens ENSP00000252211 84.0149 78.4387 choloepus_hoffmanni ENSCHOP00000010785 82.7839 77.2894 ENSG00000189298 homo_sapiens ENSP00000252211 86.4312 79.9257 dasypus_novemcinctus ENSDNOP00000019454 84.854 78.4672 ENSG00000189298 homo_sapiens ENSP00000252211 92.7509 89.9628 callithrix_jacchus ENSCJAP00000034601 92.7509 89.9628 ENSG00000189298 homo_sapiens ENSP00000252211 97.5836 96.4684 cercocebus_atys ENSCATP00000009001 97.5836 96.4684 ENSG00000189298 homo_sapiens ENSP00000252211 97.3978 96.0967 macaca_fascicularis ENSMFAP00000028646 92.0914 90.8612 ENSG00000189298 homo_sapiens ENSP00000252211 97.7695 96.6543 macaca_mulatta ENSMMUP00000009487 92.4429 91.3884 ENSG00000189298 homo_sapiens ENSP00000252211 97.7695 96.4684 macaca_nemestrina ENSMNEP00000015455 97.7695 96.4684 ENSG00000189298 homo_sapiens ENSP00000252211 97.9554 97.026 papio_anubis ENSPANP00000048084 92.6186 91.7399 ENSG00000189298 homo_sapiens ENSP00000252211 97.3978 96.2825 mandrillus_leucophaeus ENSMLEP00000027048 97.3978 96.2825 ENSG00000189298 homo_sapiens ENSP00000252211 19.145 17.658 equus_asinus ENSEASP00005053977 74.6377 68.8406 ENSG00000189298 homo_sapiens ENSP00000252211 67.1004 62.4535 equus_asinus ENSEASP00005040193 88.6978 82.5553 ENSG00000189298 homo_sapiens ENSP00000252211 34.5725 32.5279 loxodonta_africana ENSLAFP00000011798 81.5789 76.7544 ENSG00000189298 homo_sapiens ENSP00000252211 74.9071 66.171 panthera_leo ENSPLOP00000022524 82.0774 72.5051 ENSG00000189298 homo_sapiens ENSP00000252211 87.3606 79.9257 oryctolagus_cuniculus ENSOCUP00000014444 86.0806 78.7546 ENSG00000189298 homo_sapiens ENSP00000252211 88.8476 83.0855 equus_caballus ENSECAP00000087314 87.7064 82.0183 ENSG00000189298 homo_sapiens ENSP00000252211 84.5725 78.4387 marmota_marmota_marmota ENSMMMP00000023476 82.4275 76.4493 ENSG00000189298 homo_sapiens ENSP00000252211 84.9442 79.1822 microcebus_murinus ENSMICP00000009555 87.0476 81.1429 ENSG00000189298 homo_sapiens ENSP00000252211 39.2193 35.1301 ochotona_princeps ENSOPRP00000003370 52.75 47.25 ENSG00000189298 homo_sapiens ENSP00000252211 81.4126 74.9071 dipodomys_ordii ENSDORP00000013403 83.27 76.616 ENSG00000189298 homo_sapiens ENSP00000252211 95.1673 91.6357 aotus_nancymaae ENSANAP00000017535 95.1673 91.6357 ENSG00000189298 homo_sapiens ENSP00000252211 94.7955 91.0781 saimiri_boliviensis_boliviensis ENSSBOP00000004451 94.7955 91.0781 ENSG00000189298 homo_sapiens ENSP00000252211 97.3978 96.2825 chlorocebus_sabaeus ENSCSAP00000004279 97.3978 96.2825 ENSG00000189298 homo_sapiens ENSP00000252211 89.777 86.0595 carlito_syrichta ENSTSYP00000004330 88.2998 84.6435 ENSG00000189298 homo_sapiens ENSP00000252211 65.2416 56.8773 panthera_tigris_altaica ENSPTIP00000025679 68.2879 59.5331 ENSG00000189298 homo_sapiens ENSP00000252211 87.9182 82.342 prolemur_simus ENSPSMP00000022387 85.6884 80.2536 ENSG00000189298 homo_sapiens ENSP00000252211 15.2416 11.5242 myotis_lucifugus ENSMLUP00000013211 63.0769 47.6923 ENSG00000189298 homo_sapiens ENSP00000252211 97.3978 96.6543 rhinopithecus_bieti ENSRBIP00000038932 97.3978 96.6543 ENSG00000189298 homo_sapiens ENSP00000252211 84.9442 78.6245 sciurus_vulgaris ENSSVLP00005016707 88.2239 81.6602 ENSG00000189298 homo_sapiens ENSP00000252211 54.461 51.1152 procavia_capensis ENSPCAP00000010826 82.3034 77.2472 ENSG00000189298 homo_sapiens ENSP00000252211 86.4312 80.6691 otolemur_garnettii ENSOGAP00000005898 84.392 78.7659 ENSG00000189298 homo_sapiens ENSP00000252211 94.6097 91.4498 cebus_imitator ENSCCAP00000034353 95.6767 92.4812 ENSG00000189298 homo_sapiens ENSP00000252211 85.1301 78.4387 urocitellus_parryii ENSUPAP00010014272 85.4478 78.7313 ENSG00000189298 homo_sapiens ENSP00000252211 97.3978 96.6543 rhinopithecus_roxellana ENSRROP00000036762 97.3978 96.6543 ENSG00000189298 homo_sapiens ENSP00000252211 75.4647 69.3309 propithecus_coquereli ENSPCOP00000006811 86.5672 79.5309
Go ID
Go term
No. evidence
Entries
Species
Category
GO:0000122 involved_in negative regulation of transcription by RNA polymerase II 1 IDA Homo_sapiens(9606) Process GO:0000978 enables RNA polymerase II cis-regulatory region sequence-specific DNA binding 2 IBA,IDA Homo_sapiens(9606) Function GO:0000981 enables DNA-binding transcription factor activity, RNA polymerase II-specific 1 IBA Homo_sapiens(9606) Function GO:0001227 enables DNA-binding transcription repressor activity, RNA polymerase II-specific 1 IDA Homo_sapiens(9606) Function GO:0003677 enables DNA binding 1 IDA Homo_sapiens(9606) Function GO:0003682 enables chromatin binding 1 IDA Homo_sapiens(9606) Function GO:0003700 enables DNA-binding transcription factor activity 1 IDA Homo_sapiens(9606) Function GO:0005515 enables protein binding 1 IPI Homo_sapiens(9606) Function GO:0005634 located_in nucleus 1 IDA Homo_sapiens(9606) Component GO:0005654 located_in nucleoplasm 1 IDA Homo_sapiens(9606) Component GO:0005737 located_in cytoplasm 1 IDA Homo_sapiens(9606) Component GO:0006357 involved_in regulation of transcription by RNA polymerase II 1 IBA Homo_sapiens(9606) Process GO:0006914 involved_in autophagy 1 IEA Homo_sapiens(9606) Process GO:0007040 involved_in lysosome organization 1 IMP Homo_sapiens(9606) Process GO:0010507 involved_in negative regulation of autophagy 1 IMP Homo_sapiens(9606) Process GO:0043565 enables sequence-specific DNA binding 1 IDA Homo_sapiens(9606) Function GO:0045892 involved_in negative regulation of DNA-templated transcription 1 IDA Homo_sapiens(9606) Process GO:0045893 involved_in positive regulation of DNA-templated transcription 1 IDA Homo_sapiens(9606) Process GO:0046872 enables metal ion binding 1 IEA Homo_sapiens(9606) Function GO:2000773 involved_in negative regulation of cellular senescence 1 IMP Homo_sapiens(9606) Process
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