RBPWorld - a comprehensive database of RNA Binding Proteins

Functions and Diseases

RBP Type	Canonical_RBPs
Diseases	Cancer
Drug	N.A.
Main interacting RNAs	N.A.
Moonlighting functions	TF
Localizations	N.A.
BulkPerturb-seq	N.A.

Description

Ensembl ID	ENSG00000189298	Gene ID	80317	Accession	13853
Symbol	ZKSCAN3	Alias	ZF47;Zfp47;ZFP306;ZNF306;ZNF309;zfp-47;ZSCAN13;ZSCAN35;dJ874C20.1;dJ874C20.1.	Full Name	zinc finger with KRAB and SCAN domains 3
Status	Confidence	Length	19226 bases	Strand	Plus strand
Position	6 : 28349947 - 28369172	RNA binding domain	zf-met
Summary	Enables DNA-binding transcription repressor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and chromatin binding activity. Involved in several processes, including negative regulation of autophagy; negative regulation of cellular senescence; and regulation of transcription, DNA-templated. Located in cytoplasm and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

RNA binding domains (RBDs)

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Protein	Domain	Pfam ID	E-value	Domain number
ENSP00000252211	zf-met	PF12874	0.0011	1
ENSP00000341883	zf-met	PF12874	7.5e-05	1
ENSP00000366465	zf-met	PF12874	0.0011	1

Showing 1 to 3 of 3 entries

Pubmed ID	Full Name	Cell	Author	Time	Doi
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Pubmed ID	Title	Author	Time	Journal
No data available in table

Transcripts

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Name	Transcript ID	bp	Protein	Translation ID
No data available in table

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Gene Model

Click here to download ENSG00000189298's gene model file

Phenotypes

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ensgID	Trait	pValue	Pubmed ID
17897	Body Height	3.737e-005	18193045
35620	Platelet Function Tests	4.0341100E-005	-
51745	Autistic Disorder	4.5550000E-005	-
51746	Autistic Disorder	2.7384000E-005	-
95292	Forced Expiratory Volume	2E-10	21946350
95293	Respiratory Function Tests	2E-10	21946350

Showing 1 to 6 of 6 entries

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ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID
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Protein-Protein Interaction (PPI)

Click here to download ENSG00000189298's PPI file

Paralogs

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Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
ENSG00000189298	homo_sapiens	ENSP00000507525	57.1134	40.8247	homo_sapiens	ENSP00000252211	51.487	36.803
ENSG00000189298	homo_sapiens	ENSP00000506997	21.0136	14.3387	homo_sapiens	ENSP00000252211	31.5985	21.5613
ENSG00000189298	homo_sapiens	ENSP00000219091	35.7401	24.0072	homo_sapiens	ENSP00000252211	36.803	24.7212
ENSG00000189298	homo_sapiens	ENSP00000292450	60.6765	45.666	homo_sapiens	ENSP00000252211	53.3457	40.1487
ENSG00000189298	homo_sapiens	ENSP00000261332	63.587	45.6522	homo_sapiens	ENSP00000252211	43.4944	31.2268
ENSG00000189298	homo_sapiens	ENSP00000507347	45.4992	35.3519	homo_sapiens	ENSP00000252211	51.6729	40.1487
ENSG00000189298	homo_sapiens	ENSP00000359802	40.7843	28.0392	homo_sapiens	ENSP00000252211	38.6617	26.5799
ENSG00000189298	homo_sapiens	ENSP00000499415	39.1061	26.8156	homo_sapiens	ENSP00000252211	39.0335	26.7658
ENSG00000189298	homo_sapiens	ENSP00000377708	43.1985	31.9853	homo_sapiens	ENSP00000252211	43.6803	32.342
ENSG00000189298	homo_sapiens	ENSP00000321963	38.3372	23.7875	homo_sapiens	ENSP00000252211	30.855	19.145

Showing 1 to 10 of 31 entries

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Orthologs

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Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
ENSG00000189298	homo_sapiens	ENSP00000252211	99.2565	98.1413	nomascus_leucogenys	ENSNLEP00000005536	99.2565	98.1413
ENSG00000189298	homo_sapiens	ENSP00000252211	99.6283	99.2565	pan_paniscus	ENSPPAP00000031082	99.6283	99.2565
ENSG00000189298	homo_sapiens	ENSP00000252211	99.0706	98.3271	pongo_abelii	ENSPPYP00000018301	99.0706	98.3271
ENSG00000189298	homo_sapiens	ENSP00000252211	99.6283	99.0706	pan_troglodytes	ENSPTRP00000086687	99.6283	99.0706
ENSG00000189298	homo_sapiens	ENSP00000252211	99.8141	99.4424	gorilla_gorilla	ENSGGOP00000009264	99.8141	99.4424
ENSG00000189298	homo_sapiens	ENSP00000252211	84.0149	78.4387	choloepus_hoffmanni	ENSCHOP00000010785	82.7839	77.2894
ENSG00000189298	homo_sapiens	ENSP00000252211	86.4312	79.9257	dasypus_novemcinctus	ENSDNOP00000019454	84.854	78.4672
ENSG00000189298	homo_sapiens	ENSP00000252211	92.7509	89.9628	callithrix_jacchus	ENSCJAP00000034601	92.7509	89.9628
ENSG00000189298	homo_sapiens	ENSP00000252211	97.5836	96.4684	cercocebus_atys	ENSCATP00000009001	97.5836	96.4684
ENSG00000189298	homo_sapiens	ENSP00000252211	97.3978	96.0967	macaca_fascicularis	ENSMFAP00000028646	92.0914	90.8612

Showing 1 to 10 of 39 entries

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Gene Ontology

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Go ID	Go term	No. evidence	Entries	Species	Category
GO:0000978	enables RNA polymerase II cis-regulatory region sequence-specific DNA binding	2	IBA,IDA	Homo_sapiens(9606)	Function
GO:0000122	involved_in negative regulation of transcription by RNA polymerase II	1	IDA	Homo_sapiens(9606)	Process
GO:0000981	enables DNA-binding transcription factor activity, RNA polymerase II-specific	1	IBA	Homo_sapiens(9606)	Function
GO:0001227	enables DNA-binding transcription repressor activity, RNA polymerase II-specific	1	IDA	Homo_sapiens(9606)	Function
GO:0003677	enables DNA binding	1	IDA	Homo_sapiens(9606)	Function
GO:0003682	enables chromatin binding	1	IDA	Homo_sapiens(9606)	Function
GO:0003700	enables DNA-binding transcription factor activity	1	IDA	Homo_sapiens(9606)	Function
GO:0005515	enables protein binding	1	IPI	Homo_sapiens(9606)	Function
GO:0005634	located_in nucleus	1	IDA	Homo_sapiens(9606)	Component
GO:0005654	located_in nucleoplasm	1	IDA	Homo_sapiens(9606)	Component

Showing 1 to 10 of 20 entries

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Welcome to

RBP World!

Functions and Diseases

Description

RNA binding domains (RBDs)

RNA binding proteomes (RBPomes)

Literatures on RNA binding capacity

Transcripts

Gene Model

Pathways

Phenotypes

GWAS

Protein-Protein Interaction (PPI)

Paralogs

Orthologs

Gene Ontology

Expression