RBP Type	Non-canonical_RBPs
Diseases	SARS-COV-2
Drug	N.A.
Main interacting RNAs	N.A.
Moonlighting functions	N.A.
Localizations	N.A.
BulkPerturb-seq

Ensembl ID	ENSG00000187244	Gene ID	4059	Accession	6722
Symbol	BCAM	Alias	AU;LU;B-CAM;CD239;MSK19;F8/G253	Full Name	basal cell adhesion molecule (Lutheran blood group)
Status	Confidence	Length	12351 bases	Strand	Plus strand
Position	19 : 44809071 - 44821421	RNA binding domain	N.A.
Summary	This gene encodes Lutheran blood group glycoprotein, a member of the immunoglobulin superfamily and a receptor for the extracellular matrix protein, laminin. The protein contains five extracellular immunoglobulin domains, a single transmembrane domain, and a short C-terminal cytoplasmic tail. This protein may play a role in epithelial cell cancer and in vaso-occlusion of red blood cells in sickle cell disease. Polymorphisms in this gene define some of the antigens in the Lutheran system and also the Auberger system. Inactivating variants of this gene result in the recessive Lutheran null phenotype, Lu(a-b-), of the Lutheran blood group. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012]

Protein	Domain	Pfam ID	E-value	Domain number

Pubmed ID	Full Name	Cell	Author	Time	Doi

Pubmed ID	Title	Author	Time	Journal

Name	Transcript ID	bp	Protein	Translation ID
BCAM-209	ENST00000611077	3414	588aa	ENSP00000481153
BCAM-201	ENST00000270233	2409	628aa	ENSP00000270233
BCAM-202	ENST00000588303	914	No protein	-
BCAM-208	ENST00000591520	862	286aa	ENSP00000467100
BCAM-203	ENST00000588603	904	No protein	-
BCAM-206	ENST00000590108	429	No protein	-
BCAM-207	ENST00000590196	518	61aa	ENSP00000468189
BCAM-205	ENST00000589558	611	No protein	-
BCAM-204	ENST00000588714	723	No protein	-

Pathway ID	Pathway Name	Source

ensgID	Trait	pValue	Pubmed ID
22755	Anthropometry	1.9610000E-005	-
103914	Waist-Hip Ratio	4E-6	23192594

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0004888	enables transmembrane signaling receptor activity	1	TAS	Homo_sapiens(9606)	Function
GO:0005055	enables laminin receptor activity	2	IBA,IMP	Homo_sapiens(9606)	Function
GO:0005515	enables protein binding	2	IDA,IPI	Homo_sapiens(9606)	Function
GO:0005576	located_in extracellular region	1	HDA	Homo_sapiens(9606)	Component
GO:0005886	is_active_in plasma membrane	1	IBA	Homo_sapiens(9606)	Component
GO:0007155	involved_in cell adhesion	1	TAS	Homo_sapiens(9606)	Process
GO:0007160	involved_in cell-matrix adhesion	1	IMP	Homo_sapiens(9606)	Process
GO:0007165	involved_in signal transduction	1	TAS	Homo_sapiens(9606)	Process
GO:0009897	located_in external side of plasma membrane	1	IC	Homo_sapiens(9606)	Component
GO:0043236	enables laminin binding	1	IMP	Homo_sapiens(9606)	Function
GO:0062023	located_in collagen-containing extracellular matrix	1	HDA	Homo_sapiens(9606)	Component
GO:0070062	located_in extracellular exosome	1	HDA	Homo_sapiens(9606)	Component