Functions and Diseases

RBP Type Canonical_RBPs
Diseases N.A.
Drug N.A.
Main interacting RNAs N.A.
Moonlighting functions TF
Localizations N.A.
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000186130 Gene ID 10773 Accession 16764
Symbol ZBTB6 Alias ZID;ZNF482 Full Name zinc finger and BTB domain containing 6
Status Confidence Length 5268 bases Strand Minus strand
Position 9 : 122908056 - 122913323 RNA binding domain zf-met
Summary Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Located in mitochondrion and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000362763 zf-met PF12874 1.2e-05 1
ENSP00000362763 zf-met PF12874 1.2e-05 2

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal

Transcripts

Name Transcript ID bp Protein Translation ID
ZBTB6-201 ENST00000373659 4099 424aa ENSP00000362763

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000186130homo_sapiensENSP0000035821715.70018.91089homo_sapiensENSP0000036276326.179214.8585
ENSG00000186130homo_sapiensENSP0000027755420.783612.0954homo_sapiensENSP0000036276328.773616.7453
ENSG00000186130homo_sapiensENSP0000041114518.736811.3684homo_sapiensENSP0000036276320.990612.7358
ENSG00000186130homo_sapiensENSP0000027045128.93417.2589homo_sapiensENSP0000036276313.44348.01887
ENSG00000186130homo_sapiensENSP0000036119526.666715.7576homo_sapiensENSP0000036276320.754712.2642
ENSG00000186130homo_sapiensENSP0000029243123.719212.9032homo_sapiensENSP0000036276329.481116.0377
ENSG00000186130homo_sapiensENSP0000034409515.27789.52381homo_sapiensENSP0000036276318.160411.3208
ENSG00000186130homo_sapiensENSP0000026780710.41885.00511homo_sapiensENSP0000036276324.056611.5566
ENSG00000186130homo_sapiensENSP0000047674623.448313.1034homo_sapiensENSP0000036276324.056613.4434
ENSG00000186130homo_sapiensENSP0000037828622.328214.1221homo_sapiensENSP0000036276327.594317.4528
ENSG00000186130homo_sapiensENSP0000029470221.0912.0853homo_sapiensENSP0000036276320.990612.0283
ENSG00000186130homo_sapiensENSP0000033880714.9029.41177homo_sapiensENSP0000036276326.886816.9811
ENSG00000186130homo_sapiensENSP0000048575015.65386.62983homo_sapiensENSP0000036276320.04728.49057
ENSG00000186130homo_sapiensENSP0000030285513.28415.71956homo_sapiensENSP0000036276316.98117.31132
ENSG00000186130homo_sapiensENSP0000043864720.779211.8738homo_sapiensENSP0000036276326.415115.0943
ENSG00000186130homo_sapiensENSP0000036467741.830128.976homo_sapiensENSP0000036276345.28331.3679
ENSG00000186130homo_sapiensENSP0000028326820.261412.2004homo_sapiensENSP0000036276321.93413.2075
ENSG00000186130homo_sapiensENSP0000030875912.38276.4728homo_sapiensENSP0000036276331.132116.2736
ENSG00000186130homo_sapiensENSP0000049921228.062414.4766homo_sapiensENSP0000036276329.71715.3302
ENSG00000186130homo_sapiensENSP0000029380523.799615.6576homo_sapiensENSP0000036276326.886817.6887
ENSG00000186130homo_sapiensENSP0000030107321.969715.1515homo_sapiensENSP0000036276313.67929.43396
ENSG00000186130homo_sapiensENSP0000036276056.462641.7234homo_sapiensENSP0000036276358.726443.3962
ENSG00000186130homo_sapiensENSP0000045096919.79178.92857homo_sapiensENSP0000036276331.367914.1509
ENSG00000186130homo_sapiensENSP0000025300820.16359.80926homo_sapiensENSP0000036276317.45288.49057
ENSG00000186130homo_sapiensENSP0000024566322.071311.2054homo_sapiensENSP0000036276330.660415.566
ENSG00000186130homo_sapiensENSP0000038437120.113312.0397homo_sapiensENSP0000036276333.490620.0472
ENSG00000186130homo_sapiensENSP0000036001713.16156.10583homo_sapiensENSP0000036276322.877410.6132
ENSG00000186130homo_sapiensENSP000003200502515.1163homo_sapiensENSP0000036276310.14156.13208

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000186130homo_sapiensENSP00000362763100100nomascus_leucogenysENSNLEP00000046274100100
ENSG00000186130homo_sapiensENSP00000362763100100pan_paniscusENSPPAP00000007012100100
ENSG00000186130homo_sapiensENSP0000036276399.764299.7642pongo_abeliiENSPPYP0000003647599.764299.7642
ENSG00000186130homo_sapiensENSP00000362763100100pan_troglodytesENSPTRP00000062467100100
ENSG00000186130homo_sapiensENSP00000362763100100gorilla_gorillaENSGGOP00000048146100100
ENSG00000186130homo_sapiensENSP0000036276387.735878.7736ornithorhynchus_anatinusENSOANP0000004594787.323978.4038
ENSG00000186130homo_sapiensENSP0000036276388.679278.3019sarcophilus_harrisiiENSSHAP0000002564288.262977.9343
ENSG00000186130homo_sapiensENSP0000036276350.943445.0472notamacropus_eugeniiENSMEUP000000040549079.5833
ENSG00000186130homo_sapiensENSP0000036276397.877495.0472choloepus_hoffmanniENSCHOP0000001218797.877495.0472
ENSG00000186130homo_sapiensENSP0000036276391.509489.3868dasypus_novemcinctusENSDNOP0000001130197.487495.2261
ENSG00000186130homo_sapiensENSP0000036276396.226493.1604erinaceus_europaeusENSEEUP0000001190496.226493.1604
ENSG00000186130homo_sapiensENSP0000036276395.047291.7453echinops_telfairiENSETEP0000000801195.047291.7453
ENSG00000186130homo_sapiensENSP0000036276399.056698.3491callithrix_jacchusENSCJAP0000003728099.056698.3491
ENSG00000186130homo_sapiensENSP0000036276399.528399.2924cercocebus_atysENSCATP0000000654899.528399.2924
ENSG00000186130homo_sapiensENSP0000036276399.528399.2924macaca_fascicularisENSMFAP0000001068399.528399.2924
ENSG00000186130homo_sapiensENSP0000036276399.292499.0566macaca_mulattaENSMMUP0000000067799.292499.0566
ENSG00000186130homo_sapiensENSP0000036276399.528399.2924macaca_nemestrinaENSMNEP0000000596099.528399.2924
ENSG00000186130homo_sapiensENSP0000036276399.528399.0566papio_anubisENSPANP0000000142299.528399.0566
ENSG00000186130homo_sapiensENSP0000036276399.528399.2924mandrillus_leucophaeusENSMLEP0000000014299.528399.2924
ENSG00000186130homo_sapiensENSP0000036276397.641595.0472tursiops_truncatusENSTTRP0000001607497.641595.0472
ENSG00000186130homo_sapiensENSP0000036276398.113295.7547vulpes_vulpesENSVVUP0000001303683.534181.5261
ENSG00000186130homo_sapiensENSP0000036276395.990692.4528mus_spretusMGP_SPRETEiJ_P005356296.217592.6714
ENSG00000186130homo_sapiensENSP0000036276396.93495.0472equus_asinusENSEASP0000504805896.93495.0472
ENSG00000186130homo_sapiensENSP0000036276397.641593.8679capra_hircusENSCHIP0000000704097.641593.8679
ENSG00000186130homo_sapiensENSP0000036276397.405793.3962loxodonta_africanaENSLAFP0000001176297.635993.617
ENSG00000186130homo_sapiensENSP0000036276397.877495.7547panthera_leoENSPLOP0000002267298.108795.9811
ENSG00000186130homo_sapiensENSP0000036276398.113296.4623ailuropoda_melanoleucaENSAMEP0000003296198.345296.6903
ENSG00000186130homo_sapiensENSP0000036276397.641594.5755bos_indicus_hybridENSBIXP0000501509779.462676.9674
ENSG00000186130homo_sapiensENSP0000036276397.641595.9906equus_caballusENSECAP0000007299589.804888.2863
ENSG00000186130homo_sapiensENSP0000036276398.113295.9906canis_lupus_familiarisENSCAFP0084501826587.949386.0465
ENSG00000186130homo_sapiensENSP0000036276397.877495.7547panthera_pardusENSPPRP0000002651998.108795.9811
ENSG00000186130homo_sapiensENSP0000036276397.169894.8113marmota_marmota_marmotaENSMMMP0000002091897.169894.8113
ENSG00000186130homo_sapiensENSP0000036276398.113295.5189balaenoptera_musculusENSBMSP0001000276398.113295.5189
ENSG00000186130homo_sapiensENSP0000036276397.405794.1038cavia_porcellusENSCPOP0000002469397.635994.3262
ENSG00000186130homo_sapiensENSP0000036276397.641595.283felis_catusENSFCAP0000003891297.872395.5083
ENSG00000186130homo_sapiensENSP0000036276397.877496.2264ursus_americanusENSUAMP0000001943298.108796.4539
ENSG00000186130homo_sapiensENSP0000036276388.915179.2453monodelphis_domesticaENSMODP0000003039588.497778.8732
ENSG00000186130homo_sapiensENSP0000036276397.877494.8113bison_bison_bisonENSBBBP0000002167797.877494.8113
ENSG00000186130homo_sapiensENSP0000036276397.641595.283monodon_monocerosENSMMNP0001502548197.641595.283
ENSG00000186130homo_sapiensENSP0000036276396.93493.6321sus_scrofaENSSSCP0000006051596.93493.6321
ENSG00000186130homo_sapiensENSP0000036276398.820897.4057microcebus_murinusENSMICP0000004990198.820897.4057
ENSG00000186130homo_sapiensENSP0000036276397.169894.1038octodon_degusENSODEP0000002593497.399594.3262
ENSG00000186130homo_sapiensENSP0000036276396.93493.8679jaculus_jaculusENSJJAP0000000363796.93493.8679
ENSG00000186130homo_sapiensENSP0000036276397.641593.6321ovis_aries_rambouilletENSOARP0002001525590.789587.0614
ENSG00000186130homo_sapiensENSP0000036276397.877496.2264ursus_maritimusENSUMAP0000000380598.108796.4539
ENSG00000186130homo_sapiensENSP0000036276397.405795.0472physeter_catodonENSPCTP0000502053697.635995.2719
ENSG00000186130homo_sapiensENSP0000036276396.226492.217mus_caroliMGP_CAROLIEiJ_P005151296.453992.435
ENSG00000186130homo_sapiensENSP0000036276395.990692.4528mus_musculusENSMUSP0000010855496.217592.6714
ENSG00000186130homo_sapiensENSP0000036276397.641593.8679dipodomys_ordiiENSDORP0000002115497.641593.8679
ENSG00000186130homo_sapiensENSP0000036276398.820897.8774aotus_nancymaaeENSANAP0000000404598.820897.8774
ENSG00000186130homo_sapiensENSP0000036276399.056698.1132saimiri_boliviensis_boliviensisENSSBOP0000000356399.056698.1132
ENSG00000186130homo_sapiensENSP0000036276396.698193.1604vicugna_pacosENSVPAP0000000556596.926793.3806
ENSG00000186130homo_sapiensENSP0000036276399.528399.2924chlorocebus_sabaeusENSCSAP0000001920999.528399.2924
ENSG00000186130homo_sapiensENSP0000036276396.698193.6321mesocricetus_auratusENSMAUP0000000106996.926793.8534
ENSG00000186130homo_sapiensENSP0000036276397.169895.0472phocoena_sinusENSPSNP0000002303997.399595.2719
ENSG00000186130homo_sapiensENSP0000036276396.698192.9245camelus_dromedariusENSCDRP0000501080596.926793.1442
ENSG00000186130homo_sapiensENSP0000036276399.292496.6981carlito_syrichtaENSTSYP0000000089799.292496.6981
ENSG00000186130homo_sapiensENSP0000036276397.877495.7547panthera_tigris_altaicaENSPTIP0000000321698.108795.9811
ENSG00000186130homo_sapiensENSP0000036276395.047290.0943rattus_norvegicusENSRNOP0000008167095.271990.3073
ENSG00000186130homo_sapiensENSP0000036276399.056697.8774prolemur_simusENSPSMP0000003320299.056697.8774
ENSG00000186130homo_sapiensENSP0000036276396.93494.1038microtus_ochrogasterENSMOCP0000000460497.163194.3262
ENSG00000186130homo_sapiensENSP0000036276395.28390.8019sorex_araneusENSSARP0000001112495.508391.0165
ENSG00000186130homo_sapiensENSP0000036276396.93494.3396peromyscus_maniculatus_bairdiiENSPEMP0000003594997.163194.5626
ENSG00000186130homo_sapiensENSP0000036276397.877494.8113bos_mutusENSBMUP0000002020897.877494.8113
ENSG00000186130homo_sapiensENSP0000036276395.990692.4528mus_spicilegusENSMSIP0000000105496.217592.6714
ENSG00000186130homo_sapiensENSP0000036276373.584969.3396cricetulus_griseus_chok1gshdENSCGRP0000101137989.398384.2407
ENSG00000186130homo_sapiensENSP0000036276396.698193.6321cricetulus_griseus_chok1gshdENSCGRP0000101243396.926793.8534
ENSG00000186130homo_sapiensENSP0000036276397.405793.8679pteropus_vampyrusENSPVAP0000001659498.099894.5368
ENSG00000186130homo_sapiensENSP0000036276394.575591.9811myotis_lucifugusENSMLUP0000001693997.094494.431
ENSG00000186130homo_sapiensENSP0000036276389.150979.4811vombatus_ursinusENSVURP0001002232288.732479.108
ENSG00000186130homo_sapiensENSP0000036276389.150979.4811vombatus_ursinusENSVURP0001001174588.732479.108
ENSG00000186130homo_sapiensENSP0000036276397.877495.283rhinolophus_ferrumequinumENSRFEP0001003086698.108795.5083
ENSG00000186130homo_sapiensENSP0000036276397.877495.7547neovison_visonENSNVIP0000000442298.341296.2085
ENSG00000186130homo_sapiensENSP0000036276397.641594.5755bos_taurusENSBTAP0000004093794.954191.9725
ENSG00000186130homo_sapiensENSP0000036276398.113296.2264heterocephalus_glaber_femaleENSHGLP0000003076687.578985.8947
ENSG00000186130homo_sapiensENSP0000036276399.528399.2924rhinopithecus_bietiENSRBIP0000000048299.528399.2924
ENSG00000186130homo_sapiensENSP0000036276398.113295.9906canis_lupus_dingoENSCAFP0002001929298.345296.2175
ENSG00000186130homo_sapiensENSP0000036276397.169895.0472sciurus_vulgarisENSSVLP0000502612397.399595.2719
ENSG00000186130homo_sapiensENSP0000036276389.386879.4811phascolarctos_cinereusENSPCIP0000003453388.967179.108
ENSG00000186130homo_sapiensENSP0000036276396.93493.6321nannospalax_galiliENSNGAP0000002204197.163193.8534
ENSG00000186130homo_sapiensENSP0000036276397.877494.5755bos_grunniensENSBGRP0000002494579.961577.264
ENSG00000186130homo_sapiensENSP0000036276397.641594.5755chinchilla_lanigeraENSCLAP0000002393097.641594.5755
ENSG00000186130homo_sapiensENSP0000036276397.641594.3396cervus_hanglu_yarkandensisENSCHYP0000001533397.641594.3396
ENSG00000186130homo_sapiensENSP0000036276396.93493.8679catagonus_wagneriENSCWAP0000002257196.93493.8679
ENSG00000186130homo_sapiensENSP0000036276396.93495.7547otolemur_garnettiiENSOGAP0000000955896.93495.7547
ENSG00000186130homo_sapiensENSP0000036276398.584997.6415cebus_imitatorENSCCAP0000000481598.584997.6415
ENSG00000186130homo_sapiensENSP0000036276396.698194.3396urocitellus_parryiiENSUPAP0001001607796.698194.3396
ENSG00000186130homo_sapiensENSP0000036276397.641594.5755moschus_moschiferusENSMMSP0000002268097.641594.5755
ENSG00000186130homo_sapiensENSP0000036276399.528399.2924rhinopithecus_roxellanaENSRROP0000000841499.528399.2924
ENSG00000186130homo_sapiensENSP0000036276396.226492.4528mus_pahariMGP_PahariEiJ_P006252096.453992.6714
ENSG00000186130homo_sapiensENSP0000036276398.584997.4057propithecus_coquereliENSPCOP0000000090698.584997.4057
ENSG00000186130homo_sapiensENSP0000036276371.93455.1887latimeria_chalumnaeENSLACP0000000338668.693752.7027
ENSG00000186130homo_sapiensENSP0000036276379.481166.2736xenopus_tropicalisENSXETP0000010946981.204867.7108
ENSG00000186130homo_sapiensENSP0000036276389.150978.5377chrysemys_picta_belliiENSCPBP0000001304288.524677.9859
ENSG00000186130homo_sapiensENSP0000036276374.528367.9245crocodylus_porosusENSCPRP0000501518478.217871.2871
ENSG00000186130homo_sapiensENSP0000036276381.839672.1698laticauda_laticaudataENSLLTP0000000949083.614573.7349
ENSG00000186130homo_sapiensENSP0000036276382.547272.4057notechis_scutatusENSNSUP0000000145183.732173.445
ENSG00000186130homo_sapiensENSP0000036276368.396260.6132pseudonaja_textilisENSPTXP0000001272084.795375.1462
ENSG00000186130homo_sapiensENSP0000036276384.198174.5283anas_platyrhynchos_platyrhynchosENSAPLP0000003034583.411273.8318
ENSG00000186130homo_sapiensENSP0000036276383.962373.5849meleagris_gallopavoENSMGAP0000000821084.560674.1093
ENSG00000186130homo_sapiensENSP0000036276366.273660.1415serinus_canariaENSSCAP0000002253572.797966.0622
ENSG00000186130homo_sapiensENSP0000036276384.905775.2358parus_majorENSPMJP0000000037084.309174.7073
ENSG00000186130homo_sapiensENSP0000036276383.254772.8774naja_najaENSNNAP0000001958084.449873.9234
ENSG00000186130homo_sapiensENSP0000036276383.254774.2924podarcis_muralisENSPMRP0000003571278.794670.3125
ENSG00000186130homo_sapiensENSP0000036276377.122670.283geospiza_fortisENSGFOP0000000534885.378677.8068
ENSG00000186130homo_sapiensENSP0000036276383.254773.8208salvator_merianaeENSSMRP0000001475282.863973.4742
ENSG00000186130homo_sapiensENSP0000036276387.735876.8868pelodiscus_sinensisENSPSIP0000000101488.151777.2512
ENSG00000186130homo_sapiensENSP0000036276387.971776.8868gopherus_evgoodeiENSGEVP0000500785587.971776.8868
ENSG00000186130homo_sapiensENSP0000036276388.443477.1226chelonoidis_abingdoniiENSCABP0000000206185.227374.3182
ENSG00000186130homo_sapiensENSP0000036276366.273656.3679struthio_camelus_australisENSSCUP0000000048176.358764.9457
ENSG00000186130homo_sapiensENSP0000036276384.669875.4717anser_brachyrhynchusENSABRP0000002675583.878574.7664
ENSG00000186130homo_sapiensENSP0000036276383.490674.7642strigops_habroptilaENSSHBP0000501519584.285775.4762
ENSG00000186130homo_sapiensENSP0000036276342.21735.6132terrapene_carolina_triunguisENSTMTP0000002137476.170264.2553
ENSG00000186130homo_sapiensENSP0000036276385.849176.4151aquila_chrysaetos_chrysaetosENSACCP0002002118185.245975.8782
ENSG00000186130homo_sapiensENSP0000036276373.584968.1604ficedula_albicollisENSFALP0000000209063.030358.3838
ENSG00000186130homo_sapiensENSP0000036276384.905773.8208coturnix_japonicaENSCJPP0000501278384.309173.3021
ENSG00000186130homo_sapiensENSP0000036276378.773665.8019leptobrachium_leishanenseENSLLEP0000001883680.095966.9065

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0000122involved_in negative regulation of transcription by RNA polymerase II1IBAHomo_sapiens(9606)Process
GO:0000978enables RNA polymerase II cis-regulatory region sequence-specific DNA binding1IBAHomo_sapiens(9606)Function
GO:0001227enables DNA-binding transcription repressor activity, RNA polymerase II-specific1IBAHomo_sapiens(9606)Function
GO:0001817involved_in regulation of cytokine production1IBAHomo_sapiens(9606)Process
GO:0002682involved_in regulation of immune system process1IBAHomo_sapiens(9606)Process
GO:0003677enables DNA binding1TASHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005634located_in nucleus1TASHomo_sapiens(9606)Component
GO:0005654is_active_in nucleoplasm2IBA,IDAHomo_sapiens(9606)Component
GO:0005739located_in mitochondrion1IDAHomo_sapiens(9606)Component
GO:0046872enables metal ion binding1IEAHomo_sapiens(9606)Function

Expression