RBPWorld - a comprehensive database of RNA Binding Proteins

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Functions and Diseases

RBP Type	Non-canonical_RBPs
Diseases	SARS-COV-2
Drug	N.A.
Main interacting RNAs	N.A.
Moonlighting functions	Metabolic enzyme
Localizations	N.A.
BulkPerturb-seq

Description

Ensembl ID	ENSG00000185813	Gene ID	5833	Accession	8756
Symbol	PCYT2	Alias	ET;SPG82	Full Name	phosphate cytidylyltransferase 2, ethanolamine
Status	Confidence	Length	10475 bases	Strand	Minus strand
Position	17 : 81900958 - 81911432	RNA binding domain	N.A.
Summary	This gene encodes an enzyme that catalyzes the formation of CDP-ethanolamine from CTP and phosphoethanolamine in the Kennedy pathway of phospholipid synthesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010]

RNA binding domains (RBDs)

Protein	Domain	Pfam ID	E-value	Domain number

RNA binding proteomes (RBPomes)

Pubmed ID	Full Name	Cell	Author	Time	Doi

Literatures on RNA binding capacity

Pubmed ID	Title	Author	Time	Journal

Transcripts

Name	Transcript ID	bp	Protein	Translation ID
PCYT2-203	ENST00000538936	5089	389aa	ENSP00000439245
PCYT2-201	ENST00000331285	2147	311aa	ENSP00000331719
PCYT2-202	ENST00000538721	1765	407aa	ENSP00000442050
PCYT2-206	ENST00000571105	1628	367aa	ENSP00000459044
PCYT2-205	ENST00000570391	1857	357aa	ENSP00000461190
PCYT2-217	ENST00000574343	693	No protein	-
PCYT2-212	ENST00000572995	804	207aa	ENSP00000460767
PCYT2-204	ENST00000570388	1474	311aa	ENSP00000458330
PCYT2-211	ENST00000572924	732	No protein	-
PCYT2-218	ENST00000576343	1006	314aa	ENSP00000458931
PCYT2-208	ENST00000571944	366	No protein	-
PCYT2-214	ENST00000573636	913	286aa	ENSP00000459836
PCYT2-216	ENST00000574155	572	No protein	-
PCYT2-213	ENST00000573401	1028	44aa	ENSP00000458472
PCYT2-207	ENST00000571581	999	No protein	-
PCYT2-215	ENST00000573927	778	81aa	ENSP00000458727
PCYT2-210	ENST00000572473	575	34aa	ENSP00000458805
PCYT2-209	ENST00000572157	442	53aa	ENSP00000461814

Gene Model

Click here to download ENSG00000185813's gene model file

Pathways

Pathway ID	Pathway Name	Source

Phenotypes

ensgID	Trait	pValue	Pubmed ID

GWAS

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Protein-Protein Interaction (PPI)

Click here to download ENSG00000185813's PPI file

Paralogs

Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Orthologs

Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Gene Ontology

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0004306	enables ethanolamine-phosphate cytidylyltransferase activity	3	IBA,IMP,TAS	Homo_sapiens(9606)	Function
GO:0005515	enables protein binding	1	IPI	Homo_sapiens(9606)	Function
GO:0005575	is_active_in cellular_component	1	ND	Homo_sapiens(9606)	Component
GO:0005737	is_active_in cytoplasm	1	IBA	Homo_sapiens(9606)	Component
GO:0005789	located_in endoplasmic reticulum membrane	1	TAS	Homo_sapiens(9606)	Component
GO:0006646	involved_in phosphatidylethanolamine biosynthetic process	3	IBA,IEA,IMP	Homo_sapiens(9606)	Process
GO:0008654	involved_in phospholipid biosynthetic process	1	TAS	Homo_sapiens(9606)	Process

Expression