RBP Type
Canonical_RBPs
Diseases
Drug
N.A.
Main interacting RNAs
rRNA
Moonlighting functions
N.A.
Localizations
N.A.
BulkPerturb-seq
N.A.
Ensembl ID ENSG00000185414 Gene ID
51263 Accession
14036
Symbol
MRPL30
Alias
L28MT;L30MT;uL30m;MRPL28;RPML28;MRP-L28;MRP-L30;MRPL28M
Full Name
mitochondrial ribosomal protein L30
Status
Confidence
Length
18378 bases
Strand
Plus strand
Position
2 : 99181184 - 99199561
RNA binding domain
Ribosomal_L30
Summary
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Alternative splicing results in multiple transcript variants. Pseudogenes corresponding to this gene are found on chromosomes 6p and 12p. Read-through transcription also exists between this gene and the neighboring upstream lipoyltransferase 1 (LIPT1) gene. [provided by RefSeq, Mar 2011]
RNA binding domains (RBDs)
Protein
Domain
Pfam ID
E-value
Domain number
ENSP00000338057
Ribosomal_L30
PF00327 9.6e-13
1
ENSP00000386752
Ribosomal_L30
PF00327 9.6e-13
1
ENSP00000386970
Ribosomal_L30
PF00327 1.1e-05
1
RNA binding proteomes (RBPomes)
Pubmed ID
Full Name
Cell
Author
Time
Doi
Literatures on RNA binding capacity
Pubmed ID
Title
Author
Time
Journal
Name
Transcript ID
bp
Protein
Translation ID
MRPL30-205
ENST00000473743
567
No protein
-
MRPL30-201
ENST00000338148
4435
161aa
ENSP00000338057
MRPL30-202
ENST00000409145
562
101aa
ENSP00000386970
MRPL30-204
ENST00000465432
1752
No protein
-
MRPL30-203
ENST00000409841
1497
161aa
ENSP00000386752
Pathway ID
Pathway Name
Source
ensgID
Trait
pValue
Pubmed ID
ensgID SNP Chromosome Position
Trait PubmedID Or or BEAT
EFO ID
Protein-Protein Interaction (PPI)
Ensembl ID
Source
Target
Species
Protein ID
Perc_pos
Perc_id
Species
Protein ID
Perc_pos
Perc_id
ENSG00000185414
Ensembl ID
Source
Target
Species
Protein ID
Perc_pos
Perc_id
Species
Protein ID
Perc_pos
Perc_id
ENSG00000185414 homo_sapiens ENSP00000338057 98.1366 97.5155 nomascus_leucogenys ENSNLEP00000042462 98.1366 97.5155 ENSG00000185414 homo_sapiens ENSP00000338057 76.3975 72.0497 nomascus_leucogenys ENSNLEP00000025972 86.014 81.1189 ENSG00000185414 homo_sapiens ENSP00000338057 99.3789 98.7578 pan_paniscus ENSPPAP00000032064 99.3789 98.7578 ENSG00000185414 homo_sapiens ENSP00000338057 98.1366 98.1366 pongo_abelii ENSPPYP00000042998 98.1366 98.1366 ENSG00000185414 homo_sapiens ENSP00000338057 99.3789 98.7578 pan_troglodytes ENSPTRP00000021034 99.3789 98.7578 ENSG00000185414 homo_sapiens ENSP00000338057 98.7578 98.7578 gorilla_gorilla ENSGGOP00000035658 98.7578 98.7578 ENSG00000185414 homo_sapiens ENSP00000338057 91.9255 82.6087 sarcophilus_harrisii ENSSHAP00000033033 91.9255 82.6087 ENSG00000185414 homo_sapiens ENSP00000338057 88.8199 82.6087 choloepus_hoffmanni ENSCHOP00000005136 87.7301 81.5951 ENSG00000185414 homo_sapiens ENSP00000338057 91.3043 80.7453 dasypus_novemcinctus ENSDNOP00000030024 91.3043 80.7453 ENSG00000185414 homo_sapiens ENSP00000338057 85.7143 73.913 dasypus_novemcinctus ENSDNOP00000017852 86.25 74.375 ENSG00000185414 homo_sapiens ENSP00000338057 91.9255 82.6087 dasypus_novemcinctus ENSDNOP00000014475 91.9255 82.6087 ENSG00000185414 homo_sapiens ENSP00000338057 87.5776 76.3975 dasypus_novemcinctus ENSDNOP00000025715 90.3846 78.8462 ENSG00000185414 homo_sapiens ENSP00000338057 91.9255 85.0932 echinops_telfairi ENSETEP00000004076 87.0588 80.5882 ENSG00000185414 homo_sapiens ENSP00000338057 96.8944 93.7888 callithrix_jacchus ENSCJAP00000013148 78.7879 76.2626 ENSG00000185414 homo_sapiens ENSP00000338057 98.1366 95.0311 cercocebus_atys ENSCATP00000036561 98.1366 95.0311 ENSG00000185414 homo_sapiens ENSP00000338057 97.5155 93.7888 macaca_fascicularis ENSMFAP00000004020 97.5155 93.7888 ENSG00000185414 homo_sapiens ENSP00000338057 96.8944 93.7888 macaca_mulatta ENSMMUP00000070810 96.8944 93.7888 ENSG00000185414 homo_sapiens ENSP00000338057 80.7453 78.882 macaca_nemestrina ENSMNEP00000020688 97.0149 94.7761 ENSG00000185414 homo_sapiens ENSP00000338057 97.5155 94.4099 papio_anubis ENSPANP00000041815 97.5155 94.4099 ENSG00000185414 homo_sapiens ENSP00000338057 97.5155 94.4099 mandrillus_leucophaeus ENSMLEP00000007442 97.5155 94.4099 ENSG00000185414 homo_sapiens ENSP00000338057 91.9255 84.472 tursiops_truncatus ENSTTRP00000004647 85.0575 78.1609 ENSG00000185414 homo_sapiens ENSP00000338057 90.6832 83.2298 mus_spretus MGP_SPRETEiJ_P0018240 91.25 83.75 ENSG00000185414 homo_sapiens ENSP00000338057 92.5466 85.0932 equus_asinus ENSEASP00005031997 92.5466 85.0932 ENSG00000185414 homo_sapiens ENSP00000338057 92.5466 85.0932 capra_hircus ENSCHIP00000028746 92.5466 85.0932 ENSG00000185414 homo_sapiens ENSP00000338057 92.5466 85.0932 loxodonta_africana ENSLAFP00000006835 81.4208 74.8634 ENSG00000185414 homo_sapiens ENSP00000338057 95.0311 88.1988 panthera_leo ENSPLOP00000018455 72.5118 67.2986 ENSG00000185414 homo_sapiens ENSP00000338057 94.4099 86.3354 ailuropoda_melanoleuca ENSAMEP00000026474 85.8757 78.5311 ENSG00000185414 homo_sapiens ENSP00000338057 91.3043 83.2298 bos_indicus_hybrid ENSBIXP00005008738 60.9958 55.6017 ENSG00000185414 homo_sapiens ENSP00000338057 93.1677 86.9565 oryctolagus_cuniculus ENSOCUP00000003556 93.1677 86.9565 ENSG00000185414 homo_sapiens ENSP00000338057 93.1677 85.7143 equus_caballus ENSECAP00000081887 58.3658 53.6965 ENSG00000185414 homo_sapiens ENSP00000338057 95.0311 87.5776 canis_lupus_familiaris ENSCAFP00845024837 95.0311 87.5776 ENSG00000185414 homo_sapiens ENSP00000338057 95.0311 88.1988 panthera_pardus ENSPPRP00000016692 95.0311 88.1988 ENSG00000185414 homo_sapiens ENSP00000338057 91.3043 87.5776 marmota_marmota_marmota ENSMMMP00000022580 94.8387 90.9677 ENSG00000185414 homo_sapiens ENSP00000338057 92.5466 85.7143 balaenoptera_musculus ENSBMSP00010019039 92.5466 85.7143 ENSG00000185414 homo_sapiens ENSP00000338057 89.441 83.2298 cavia_porcellus ENSCPOP00000009619 92.9032 86.4516 ENSG00000185414 homo_sapiens ENSP00000338057 95.0311 88.8199 felis_catus ENSFCAP00000016511 60.7143 56.746 ENSG00000185414 homo_sapiens ENSP00000338057 64.5963 55.9006 felis_catus ENSFCAP00000058569 57.7778 50 ENSG00000185414 homo_sapiens ENSP00000338057 93.7888 85.0932 ursus_americanus ENSUAMP00000019673 93.7888 85.0932 ENSG00000185414 homo_sapiens ENSP00000338057 61.4907 50.9317 bison_bison_bison ENSBBBP00000026481 53.5135 44.3243 ENSG00000185414 homo_sapiens ENSP00000338057 91.3043 83.2298 bison_bison_bison ENSBBBP00000015491 91.3043 83.2298 ENSG00000185414 homo_sapiens ENSP00000338057 86.9565 78.2609 monodon_monoceros ENSMMNP00015029784 86.9565 78.2609 ENSG00000185414 homo_sapiens ENSP00000338057 91.9255 84.472 monodon_monoceros ENSMMNP00015021217 91.9255 84.472 ENSG00000185414 homo_sapiens ENSP00000338057 93.1677 88.1988 sus_scrofa ENSSSCP00000068548 93.1677 88.1988 ENSG00000185414 homo_sapiens ENSP00000338057 82.6087 78.2609 microcebus_murinus ENSMICP00000016554 86.9281 82.3529 ENSG00000185414 homo_sapiens ENSP00000338057 94.4099 90.0621 microcebus_murinus ENSMICP00000010575 94.4099 90.0621 ENSG00000185414 homo_sapiens ENSP00000338057 77.6398 74.5342 microcebus_murinus ENSMICP00000020467 92.5926 88.8889 ENSG00000185414 homo_sapiens ENSP00000338057 88.8199 81.9876 octodon_degus ENSODEP00000013464 88.8199 81.9876 ENSG00000185414 homo_sapiens ENSP00000338057 90.0621 83.8509 octodon_degus ENSODEP00000008056 90.0621 83.8509 ENSG00000185414 homo_sapiens ENSP00000338057 88.8199 81.9876 octodon_degus ENSODEP00000025857 79.8883 73.743 ENSG00000185414 homo_sapiens ENSP00000338057 86.3354 77.6398 octodon_degus ENSODEP00000025434 77.6536 69.8324 ENSG00000185414 homo_sapiens ENSP00000338057 90.0621 83.2298 jaculus_jaculus ENSJJAP00000003232 90.0621 83.2298 ENSG00000185414 homo_sapiens ENSP00000338057 91.3043 83.8509 ovis_aries_rambouillet ENSOARP00020017767 91.3043 83.8509 ENSG00000185414 homo_sapiens ENSP00000338057 91.9255 85.0932 ovis_aries_rambouillet ENSOARP00020016142 91.9255 85.0932 ENSG00000185414 homo_sapiens ENSP00000338057 92.5466 84.472 ursus_maritimus ENSUMAP00000011925 81.8681 74.7253 ENSG00000185414 homo_sapiens ENSP00000338057 90.0621 81.3665 ochotona_princeps ENSOPRP00000006713 86.8263 78.4431 ENSG00000185414 homo_sapiens ENSP00000338057 73.2919 63.354 delphinapterus_leucas ENSDLEP00000015968 75.641 65.3846 ENSG00000185414 homo_sapiens ENSP00000338057 87.5776 78.882 delphinapterus_leucas ENSDLEP00000028305 87.5776 78.882 ENSG00000185414 homo_sapiens ENSP00000338057 91.9255 84.472 delphinapterus_leucas ENSDLEP00000001645 91.9255 84.472 ENSG00000185414 homo_sapiens ENSP00000338057 87.5776 78.2609 physeter_catodon ENSPCTP00005013614 87.5776 78.2609 ENSG00000185414 homo_sapiens ENSP00000338057 91.3043 83.8509 mus_caroli MGP_CAROLIEiJ_P0017238 91.875 84.375 ENSG00000185414 homo_sapiens ENSP00000338057 89.441 81.9876 mus_musculus ENSMUSP00000027256 90 82.5 ENSG00000185414 homo_sapiens ENSP00000338057 89.441 83.2298 dipodomys_ordii ENSDORP00000010087 88.8889 82.716 ENSG00000185414 homo_sapiens ENSP00000338057 91.9255 84.472 mustela_putorius_furo ENSMPUP00000010995 92.5 85 ENSG00000185414 homo_sapiens ENSP00000338057 96.8944 94.4099 aotus_nancymaae ENSANAP00000020956 96.8944 94.4099 ENSG00000185414 homo_sapiens ENSP00000338057 96.2733 94.4099 saimiri_boliviensis_boliviensis ENSSBOP00000040689 96.2733 94.4099 ENSG00000185414 homo_sapiens ENSP00000338057 51.5528 49.0683 saimiri_boliviensis_boliviensis ENSSBOP00000010595 95.4023 90.8046 ENSG00000185414 homo_sapiens ENSP00000338057 96.8944 93.1677 chlorocebus_sabaeus ENSCSAP00000013255 96.8944 93.1677 ENSG00000185414 homo_sapiens ENSP00000338057 63.9752 60.8696 tupaia_belangeri ENSTBEP00000006665 60.2339 57.3099 ENSG00000185414 homo_sapiens ENSP00000338057 72.6708 63.9752 mesocricetus_auratus ENSMAUP00000015313 81.8182 72.028 ENSG00000185414 homo_sapiens ENSP00000338057 88.1988 82.6087 mesocricetus_auratus ENSMAUP00000024491 85.5422 80.1205 ENSG00000185414 homo_sapiens ENSP00000338057 91.3043 85.0932 mesocricetus_auratus ENSMAUP00000019334 85.4651 79.6512 ENSG00000185414 homo_sapiens ENSP00000338057 73.2919 62.7329 phocoena_sinus ENSPSNP00000019586 75.641 64.7436 ENSG00000185414 homo_sapiens ENSP00000338057 85.0932 75.7764 phocoena_sinus ENSPSNP00000027352 85.0932 75.7764 ENSG00000185414 homo_sapiens ENSP00000338057 91.9255 84.472 phocoena_sinus ENSPSNP00000009937 91.9255 84.472 ENSG00000185414 homo_sapiens ENSP00000338057 92.5466 85.0932 camelus_dromedarius ENSCDRP00005026032 92.5466 85.0932 ENSG00000185414 homo_sapiens ENSP00000338057 80.1242 74.5342 carlito_syrichta ENSTSYP00000023768 87.1622 81.0811 ENSG00000185414 homo_sapiens ENSP00000338057 94.4099 90.6832 carlito_syrichta ENSTSYP00000031451 94.4099 90.6832 ENSG00000185414 homo_sapiens ENSP00000338057 95.0311 88.1988 panthera_tigris_altaica ENSPTIP00000002003 95.0311 88.1988 ENSG00000185414 homo_sapiens ENSP00000338057 74.5342 63.354 rattus_norvegicus ENSRNOP00000079080 75.4717 64.1509 ENSG00000185414 homo_sapiens ENSP00000338057 91.3043 84.472 rattus_norvegicus ENSRNOP00000083246 79.0323 73.1183 ENSG00000185414 homo_sapiens ENSP00000338057 93.7888 89.441 prolemur_simus ENSPSMP00000027783 93.7888 89.441 ENSG00000185414 homo_sapiens ENSP00000338057 90.6832 84.472 microtus_ochrogaster ENSMOCP00000006049 91.25 85 ENSG00000185414 homo_sapiens ENSP00000338057 50.9317 45.3416 sorex_araneus ENSSARP00000000780 60.2941 53.6765 ENSG00000185414 homo_sapiens ENSP00000338057 91.3043 85.7143 peromyscus_maniculatus_bairdii ENSPEMP00000020326 91.875 86.25 ENSG00000185414 homo_sapiens ENSP00000338057 88.8199 80.7453 peromyscus_maniculatus_bairdii ENSPEMP00000005255 89.375 81.25 ENSG00000185414 homo_sapiens ENSP00000338057 91.3043 83.8509 bos_mutus ENSBMUP00000001904 91.3043 83.8509 ENSG00000185414 homo_sapiens ENSP00000338057 88.8199 80.7453 mus_spicilegus ENSMSIP00000012657 89.375 81.25 ENSG00000185414 homo_sapiens ENSP00000338057 83.8509 72.6708 mus_spicilegus ENSMSIP00000021222 84.375 73.125 ENSG00000185414 homo_sapiens ENSP00000338057 90.0621 82.6087 mus_spicilegus ENSMSIP00000007332 90.625 83.125 ENSG00000185414 homo_sapiens ENSP00000338057 86.3354 75.7764 mus_spicilegus ENSMSIP00000004254 89.1026 78.2051 ENSG00000185414 homo_sapiens ENSP00000338057 91.3043 85.7143 cricetulus_griseus_chok1gshd ENSCGRP00001004754 91.875 86.25 ENSG00000185414 homo_sapiens ENSP00000338057 93.1677 83.2298 pteropus_vampyrus ENSPVAP00000006219 87.7193 78.3626 ENSG00000185414 homo_sapiens ENSP00000338057 93.1677 84.472 myotis_lucifugus ENSMLUP00000021261 93.1677 84.472 ENSG00000185414 homo_sapiens ENSP00000338057 89.441 78.2609 vombatus_ursinus ENSVURP00010000293 89.441 78.2609 ENSG00000185414 homo_sapiens ENSP00000338057 93.1677 85.7143 rhinolophus_ferrumequinum ENSRFEP00010033451 89.2857 82.1429 ENSG00000185414 homo_sapiens ENSP00000338057 91.9255 83.8509 neovison_vison ENSNVIP00000030201 92.5 84.375 ENSG00000185414 homo_sapiens ENSP00000338057 91.9255 83.8509 bos_taurus ENSBTAP00000005183 91.9255 83.8509 ENSG00000185414 homo_sapiens ENSP00000338057 59.6273 49.6894 bos_taurus ENSBTAP00000070104 53.6313 44.6927 ENSG00000185414 homo_sapiens ENSP00000338057 90.0621 85.7143 rhinopithecus_bieti ENSRBIP00000036252 93.5484 89.0323 ENSG00000185414 homo_sapiens ENSP00000338057 94.4099 86.9565 canis_lupus_dingo ENSCAFP00020032050 94.4099 86.9565 ENSG00000185414 homo_sapiens ENSP00000338057 90.6832 85.0932 sciurus_vulgaris ENSSVLP00005014365 90.6832 85.0932 ENSG00000185414 homo_sapiens ENSP00000338057 91.9255 85.7143 sciurus_vulgaris ENSSVLP00005018675 91.9255 85.7143 ENSG00000185414 homo_sapiens ENSP00000338057 89.441 79.5031 phascolarctos_cinereus ENSPCIP00000047432 89.441 79.5031 ENSG00000185414 homo_sapiens ENSP00000338057 88.1988 82.6087 nannospalax_galili ENSNGAP00000021014 88.75 83.125 ENSG00000185414 homo_sapiens ENSP00000338057 60.2484 50.9317 bos_grunniens ENSBGRP00000027414 54.8023 46.3277 ENSG00000185414 homo_sapiens ENSP00000338057 91.3043 83.8509 bos_grunniens ENSBGRP00000042939 91.3043 83.8509 ENSG00000185414 homo_sapiens ENSP00000338057 93.1677 86.9565 chinchilla_lanigera ENSCLAP00000008109 83.7989 78.2123 ENSG00000185414 homo_sapiens ENSP00000338057 92.5466 86.9565 cervus_hanglu_yarkandensis ENSCHYP00000015171 92.5466 86.9565 ENSG00000185414 homo_sapiens ENSP00000338057 94.4099 87.5776 catagonus_wagneri ENSCWAP00000001290 94.4099 87.5776 ENSG00000185414 homo_sapiens ENSP00000338057 90.6832 85.7143 otolemur_garnettii ENSOGAP00000002000 87.4251 82.6347 ENSG00000185414 homo_sapiens ENSP00000338057 88.1988 80.1242 otolemur_garnettii ENSOGAP00000016336 88.1988 80.1242 ENSG00000185414 homo_sapiens ENSP00000338057 86.3354 79.5031 otolemur_garnettii ENSOGAP00000019310 87.9747 81.0127 ENSG00000185414 homo_sapiens ENSP00000338057 91.3043 88.8199 cebus_imitator ENSCCAP00000003034 92.4528 89.9371 ENSG00000185414 homo_sapiens ENSP00000338057 94.4099 92.5466 cebus_imitator ENSCCAP00000032871 95 93.125 ENSG00000185414 homo_sapiens ENSP00000338057 91.3043 86.9565 urocitellus_parryii ENSUPAP00010006117 94.8387 90.3226 ENSG00000185414 homo_sapiens ENSP00000338057 91.9255 85.0932 moschus_moschiferus ENSMMSP00000002631 91.9255 85.0932 ENSG00000185414 homo_sapiens ENSP00000338057 98.1366 95.0311 rhinopithecus_roxellana ENSRROP00000043247 98.1366 95.0311 ENSG00000185414 homo_sapiens ENSP00000338057 90.6832 83.2298 mus_pahari MGP_PahariEiJ_P0072586 91.25 83.75 ENSG00000185414 homo_sapiens ENSP00000338057 93.7888 88.1988 propithecus_coquereli ENSPCOP00000005238 93.7888 88.1988 ENSG00000185414 homo_sapiens ENSP00000338057 89.441 83.2298 propithecus_coquereli ENSPCOP00000000351 89.441 83.2298 ENSG00000185414 homo_sapiens ENSP00000338057 68.9441 52.1739 gadus_morhua ENSGMOP00000013450 70.2532 53.1646 ENSG00000185414 homo_sapiens ENSP00000338057 63.9752 52.795 sphenodon_punctatus ENSSPUP00000000839 58.5227 48.2955 ENSG00000185414 homo_sapiens ENSP00000338057 70.8075 61.4907 gopherus_evgoodei ENSGEVP00005000140 78.6207 68.2759 ENSG00000185414 homo_sapiens ENSP00000338057 69.5652 50.9317 hucho_hucho ENSHHUP00000047090 63.2768 46.3277 ENSG00000185414 homo_sapiens ENSP00000338057 59.0062 41.6149 coturnix_japonica ENSCJPP00005000103 59.7484 42.1384
Go ID
Go term
No. evidence
Entries
Species
Category
GO:0003735 enables structural constituent of ribosome 1 IEA Homo_sapiens(9606) Function GO:0005739 is_active_in mitochondrion 2 IBA,IDA Homo_sapiens(9606) Component GO:0005743 located_in mitochondrial inner membrane 2 NAS,TAS Homo_sapiens(9606) Component GO:0005762 part_of mitochondrial large ribosomal subunit 2 IDA,NAS Homo_sapiens(9606) Component GO:0032543 involved_in mitochondrial translation 1 NAS Homo_sapiens(9606) Process
Copyright © 2023, Bioinformatics Center, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, China. All Rights Reserved.
