Functions and Diseases

RBP Type Canonical_RBPs
Diseases Cancer
Drug Drug
Main interacting RNAs N.A.
Moonlighting functions TF
Localizations N.A.
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000184937 Gene ID 7490 Accession 12796
Symbol WT1 Alias GUD;AWT1;WAGR;WT-1;WT33;NPHS4;WIT-2 Full Name WT1 transcription factor
Status Confidence Length 47790 bases Strand Minus strand
Position 11 : 32387775 - 32435564 RNA binding domain WT1
Summary This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the normal development of the urogenital system, and it is mutated in a small subset of patients with Wilms tumor. This gene exhibits complex tissue-specific and polymorphic imprinting pattern, with biallelic, and monoallelic expression from the maternal and paternal alleles in different tissues. Multiple transcript variants have been described. In several variants, there is evidence for the use of a non-AUG (CUG) translation initiation codon upstream of, and in-frame with the first AUG. Authors of PMID:7926762 also provide evidence that WT1 mRNA undergoes RNA editing in human and rat, and that this process is tissue-restricted and developmentally regulated. [provided by RefSeq, Mar 2015]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000331327 WT1 PF02165 4e-154 1
ENSP00000492269 WT1 PF02165 4e-154 1
ENSP00000413452 WT1 PF02165 1.6e-150 1
ENSP00000415516 WT1 PF02165 1.6e-150 1
ENSP00000368368 WT1 PF02165 4.1e-123 1
ENSP00000491984 WT1 PF02165 3.8e-89 1
ENSP00000435307 WT1 PF02165 5e-89 1
ENSP00000368370 WT1 PF02165 1.3e-85 1
ENSP00000435624 WT1 PF02165 6.9e-23 1

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal

Transcripts

Name Transcript ID bp Protein Translation ID
WT1-203 ENST00000379079 2466 302aa ENSP00000368370
WT1-205 ENST00000452863 3031 522aa ENSP00000415516
WT1-202 ENST00000379077 3186 322aa ENSP00000368368
WT1-209 ENST00000530998 2421 288aa ENSP00000435307
WT1-201 ENST00000332351 2987 502aa ENSP00000331327
WT1-220 ENST00000651819 1650 No protein -
WT1-222 ENST00000652724 1794 No protein -
WT1-217 ENST00000651533 1534 No protein -
WT1-218 ENST00000651668 1434 No protein -
WT1-214 ENST00000650861 3069 No protein -
WT1-221 ENST00000652579 1757 No protein -
WT1-212 ENST00000640146 2018 297aa ENSP00000491984
WT1-211 ENST00000639907 1630 No protein -
WT1-213 ENST00000650745 2305 No protein -
WT1-219 ENST00000651794 2309 No protein -
WT1-216 ENST00000651459 1086 43aa ENSP00000498574
WT1-204 ENST00000448076 2114 519aa ENSP00000413452
WT1-208 ENST00000527882 551 178aa ENSP00000435624
WT1-215 ENST00000650986 233 No protein -
WT1-210 ENST00000639563 1518 505aa ENSP00000492269
WT1-206 ENST00000526685 980 No protein -
WT1-207 ENST00000527775 578 No protein -

Gene Model

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID
92629Hernia, Inguinal4E-1426686553

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000184937homo_sapiensENSP0000024248030.882421.0084homo_sapiensENSP0000041551628.160919.1571
ENSG00000184937homo_sapiensENSP0000023993827.808519.337homo_sapiensENSP0000041551628.927220.1149
ENSG00000184937homo_sapiensENSP0000041968723.662617.4897homo_sapiensENSP0000041551622.030716.2835
ENSG00000184937homo_sapiensENSP0000031805735.400526.0982homo_sapiensENSP0000041551626.245219.3487

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000184937homo_sapiensENSP0000041551657.279757.0881nomascus_leucogenysENSNLEP0000004689299.006698.6755
ENSG00000184937homo_sapiensENSP0000041551681.992381.9923pan_paniscusENSPPAP0000002118799.766999.7669
ENSG00000184937homo_sapiensENSP0000041551699.233798.8506pongo_abeliiENSPPYP0000004140699.233798.8506
ENSG00000184937homo_sapiensENSP0000041551698.275998.0843pan_troglodytesENSPTRP0000008767399.805599.6109
ENSG00000184937homo_sapiensENSP0000041551695.593995.2107gorilla_gorillaENSGGOP0000003290396.705496.3178
ENSG00000184937homo_sapiensENSP0000041551686.5981.8008ornithorhynchus_anatinusENSOANP0000002385461.163757.7808
ENSG00000184937homo_sapiensENSP0000041551694.061390.9962sarcophilus_harrisiiENSSHAP0000003672194.60591.5222
ENSG00000184937homo_sapiensENSP0000041551679.118878.3525choloepus_hoffmanniENSCHOP0000000552581.459680.6706
ENSG00000184937homo_sapiensENSP0000041551695.402394.4444dasypus_novemcinctusENSDNOP0000000281795.585494.6257
ENSG00000184937homo_sapiensENSP0000041551657.471357.0881erinaceus_europaeusENSEEUP0000000658899.667899.0033
ENSG00000184937homo_sapiensENSP0000041551677.011576.2452echinops_telfairiENSETEP0000000054897.101496.1353
ENSG00000184937homo_sapiensENSP0000041551698.275997.1264callithrix_jacchusENSCJAP0000001088298.275997.1264
ENSG00000184937homo_sapiensENSP0000041551697.509697.1264cercocebus_atysENSCATP0000002244298.262697.8764
ENSG00000184937homo_sapiensENSP0000041551698.084397.5096macaca_fascicularisENSMFAP0000001535098.461597.8846
ENSG00000184937homo_sapiensENSP0000041551697.509697.1264macaca_mulattaENSMMUP0000001293898.452698.0658
ENSG00000184937homo_sapiensENSP0000041551697.509697.1264macaca_nemestrinaENSMNEP0000000222198.452698.0658
ENSG00000184937homo_sapiensENSP0000041551698.467497.8927papio_anubisENSPANP0000003941498.467497.8927
ENSG00000184937homo_sapiensENSP0000041551682.758682.3755mandrillus_leucophaeusENSMLEP0000003203998.630198.1735
ENSG00000184937homo_sapiensENSP0000041551663.793163.6015tursiops_truncatusENSTTRP0000001216199.107198.8095
ENSG00000184937homo_sapiensENSP0000041551693.103491.7625vulpes_vulpesENSVVUP0000002229494.552593.1907
ENSG00000184937homo_sapiensENSP0000041551684.482883.7165mus_spretusMGP_SPRETEiJ_P005557798.218397.3274
ENSG00000184937homo_sapiensENSP0000041551671.072870.6897equus_asinusENSEASP0000501965587.706987.234
ENSG00000184937homo_sapiensENSP0000041551685.632285.4406capra_hircusENSCHIP0000001058699.333399.1111
ENSG00000184937homo_sapiensENSP0000041551685.057584.6743loxodonta_africanaENSLAFP0000002227198.666798.2222
ENSG00000184937homo_sapiensENSP0000041551697.701196.3602panthera_leoENSPLOP0000000762197.514396.1759
ENSG00000184937homo_sapiensENSP0000041551689.463688.3142ailuropoda_melanoleucaENSAMEP0000003685097.494896.2422
ENSG00000184937homo_sapiensENSP0000041551696.360295.2107bos_indicus_hybridENSBIXP0000503299197.104295.9459
ENSG00000184937homo_sapiensENSP0000041551656.896656.705oryctolagus_cuniculusENSOCUP0000000509998.344498.0132
ENSG00000184937homo_sapiensENSP0000041551696.168695.2107equus_caballusENSECAP0000002708196.353295.3935
ENSG00000184937homo_sapiensENSP0000041551698.084396.3602canis_lupus_familiarisENSCAFP0084503785397.896896.1759
ENSG00000184937homo_sapiensENSP0000041551696.934995.7854panthera_pardusENSPPRP0000000316297.683496.5251
ENSG00000184937homo_sapiensENSP0000041551657.088156.705marmota_marmota_marmotaENSMMMP0000000841998.675598.0132
ENSG00000184937homo_sapiensENSP0000041551697.701196.1686balaenoptera_musculusENSBMSP0001001716297.514395.9847
ENSG00000184937homo_sapiensENSP0000041551659.770158.4291cavia_porcellusENSCPOP0000003253797.595.3125
ENSG00000184937homo_sapiensENSP0000041551697.701196.3602felis_catusENSFCAP0000004319497.514396.1759
ENSG00000184937homo_sapiensENSP0000041551697.31896.1686ursus_americanusENSUAMP0000002314497.31896.1686
ENSG00000184937homo_sapiensENSP0000041551684.865982.567monodelphis_domesticaENSMODP0000001205593.657591.1205
ENSG00000184937homo_sapiensENSP0000041551653.448352.4904bison_bison_bisonENSBBBP0000000341895.876394.1581
ENSG00000184937homo_sapiensENSP0000041551697.31895.4023monodon_monocerosENSMMNP0001502598597.131995.2199
ENSG00000184937homo_sapiensENSP0000041551696.934995.2107sus_scrofaENSSSCP0000001941797.307795.5769
ENSG00000184937homo_sapiensENSP0000041551697.701197.318microcebus_murinusENSMICP0000004968597.701197.318
ENSG00000184937homo_sapiensENSP0000041551644.827644.2529octodon_degusENSODEP0000002099095.121993.9024
ENSG00000184937homo_sapiensENSP0000041551695.97794.636ovis_aries_rambouilletENSOARP0002001126696.531895.183
ENSG00000184937homo_sapiensENSP0000041551656.321855.364ursus_maritimusENSUMAP0000002681096.393494.7541
ENSG00000184937homo_sapiensENSP0000041551657.279756.705ochotona_princepsENSOPRP0000001435199.335598.3389
ENSG00000184937homo_sapiensENSP0000041551697.31895.4023delphinapterus_leucasENSDLEP0000001778497.131995.2199
ENSG00000184937homo_sapiensENSP0000041551697.701196.1686physeter_catodonENSPCTP0000501971497.514395.9847
ENSG00000184937homo_sapiensENSP0000041551694.252992.9119mus_caroliMGP_CAROLIEiJ_P005348395.164493.8104
ENSG00000184937homo_sapiensENSP0000041551693.869792.5287mus_musculusENSMUSP0000011789194.777693.4236
ENSG00000184937homo_sapiensENSP0000041551685.440685.0575dipodomys_ordiiENSDORP0000002737299.111198.6667
ENSG00000184937homo_sapiensENSP0000041551682.56782.567mustela_putorius_furoENSMPUP0000001121599.538199.5381
ENSG00000184937homo_sapiensENSP0000041551693.678292.9119aotus_nancymaaeENSANAP0000001446098.192897.3896
ENSG00000184937homo_sapiensENSP0000041551685.057584.4828saimiri_boliviensis_boliviensisENSSBOP0000000750697.582496.9231
ENSG00000184937homo_sapiensENSP0000041551657.471356.8966vicugna_pacosENSVPAP0000000724599.667898.6711
ENSG00000184937homo_sapiensENSP0000041551661.111161.1111chlorocebus_sabaeusENSCSAP0000000157299.687599.6875
ENSG00000184937homo_sapiensENSP0000041551644.252944.0613tupaia_belangeriENSTBEP0000000628781.914981.5603
ENSG00000184937homo_sapiensENSP0000041551693.869792.3372mesocricetus_auratusENSMAUP0000000599194.961293.4109
ENSG00000184937homo_sapiensENSP0000041551696.743395.0192phocoena_sinusENSPSNP0000002040797.115495.3846
ENSG00000184937homo_sapiensENSP0000041551697.126495.977camelus_dromedariusENSCDRP0000502827697.596.3462
ENSG00000184937homo_sapiensENSP0000041551651.724150.9579carlito_syrichtaENSTSYP0000002007994.736893.3333
ENSG00000184937homo_sapiensENSP0000041551652.298952.1073panthera_tigris_altaicaENSPTIP0000000518599.272798.9091
ENSG00000184937homo_sapiensENSP0000041551693.869792.3372rattus_norvegicusENSRNOP0000007861194.961293.4109
ENSG00000184937homo_sapiensENSP0000041551697.31896.9349prolemur_simusENSPSMP0000002179797.31896.9349
ENSG00000184937homo_sapiensENSP0000041551693.29591.7625microtus_ochrogasterENSMOCP0000000656994.379892.8295
ENSG00000184937homo_sapiensENSP0000041551656.896656.5134sorex_araneusENSSARP000000001879998.3333
ENSG00000184937homo_sapiensENSP0000041551693.103491.7625peromyscus_maniculatus_bairdiiENSPEMP0000000155093.641692.2929
ENSG00000184937homo_sapiensENSP0000041551675.478975.2874bos_mutusENSBMUP0000001035476.061875.8687
ENSG00000184937homo_sapiensENSP0000041551693.869792.3372mus_spicilegusENSMSIP0000001687594.777693.2302
ENSG00000184937homo_sapiensENSP0000041551693.29591.7625cricetulus_griseus_chok1gshdENSCGRP0000100412694.379892.8295
ENSG00000184937homo_sapiensENSP0000041551649.808449.8084pteropus_vampyrusENSPVAP0000000651099.616999.6169
ENSG00000184937homo_sapiensENSP0000041551679.693578.7356myotis_lucifugusENSMLUP0000002013695.852594.7005
ENSG00000184937homo_sapiensENSP0000041551692.337290.0383vombatus_ursinusENSVURP0001001741393.774391.4397
ENSG00000184937homo_sapiensENSP0000041551696.551795.4023rhinolophus_ferrumequinumENSRFEP0001000917196.551795.4023
ENSG00000184937homo_sapiensENSP0000041551672.413872.4138neovison_visonENSNVIP0000000593773.114173.1141
ENSG00000184937homo_sapiensENSP0000041551695.210794.0613bos_taurusENSBTAP0000007133295.210794.0613
ENSG00000184937homo_sapiensENSP0000041551656.321854.7893heterocephalus_glaber_femaleENSHGLP0000000582897.35194.702
ENSG00000184937homo_sapiensENSP0000041551696.934996.5517rhinopithecus_bietiENSRBIP0000003049598.252497.8641
ENSG00000184937homo_sapiensENSP0000041551696.934995.4023canis_lupus_dingoENSCAFP0002000307496.749595.2199
ENSG00000184937homo_sapiensENSP0000041551697.31896.1686sciurus_vulgarisENSSVLP0000500795797.131995.9847
ENSG00000184937homo_sapiensENSP0000041551691.95489.4636phascolarctos_cinereusENSPCIP0000004864793.385290.856
ENSG00000184937homo_sapiensENSP0000041551694.252992.9119procavia_capensisENSPCAP0000000208094.980793.6293
ENSG00000184937homo_sapiensENSP0000041551685.440685.0575nannospalax_galiliENSNGAP0000002378798.891398.4479
ENSG00000184937homo_sapiensENSP0000041551697.31895.977bos_grunniensENSBGRP0000002363397.131995.7935
ENSG00000184937homo_sapiensENSP0000041551659.770158.8123chinchilla_lanigeraENSCLAP0000000185797.595.9375
ENSG00000184937homo_sapiensENSP0000041551697.31896.3602cervus_hanglu_yarkandensisENSCHYP0000001296397.131996.1759
ENSG00000184937homo_sapiensENSP0000041551697.126495.4023catagonus_wagneriENSCWAP0000000616096.940795.2199
ENSG00000184937homo_sapiensENSP0000041551697.126495.977ictidomys_tridecemlineatusENSSTOP0000001676596.940795.7935
ENSG00000184937homo_sapiensENSP0000041551681.800881.8008otolemur_garnettiiENSOGAP0000000637799.302399.3023
ENSG00000184937homo_sapiensENSP0000041551696.934996.3602cebus_imitatorENSCCAP0000001315997.872397.2921
ENSG00000184937homo_sapiensENSP0000041551697.126495.977urocitellus_parryiiENSUPAP0001002394597.126495.977
ENSG00000184937homo_sapiensENSP0000041551697.31895.4023moschus_moschiferusENSMMSP0000002047097.131995.2199
ENSG00000184937homo_sapiensENSP0000041551681.034580.8429rhinopithecus_roxellanaENSRROP0000000513284.684.4
ENSG00000184937homo_sapiensENSP0000041551684.291283.7165mus_pahariMGP_PahariEiJ_P006446097.995597.3274
ENSG00000184937homo_sapiensENSP0000041551697.126496.7433propithecus_coquereliENSPCOP0000001727597.126496.7433
ENSG00000184937homo_sapiensENSP0000041551639.080532.3755petromyzon_marinusENSPMAP000000098536856.3333
ENSG00000184937homo_sapiensENSP0000041551651.532643.6782eptatretus_burgeriENSEBUP0000002259160.585651.3514
ENSG00000184937homo_sapiensENSP0000041551664.942559.5785callorhinchus_miliiENSCMIP0000004361084.962477.9449
ENSG00000184937homo_sapiensENSP0000041551672.605468.0077latimeria_chalumnaeENSLACP0000001859989.810484.1232
ENSG00000184937homo_sapiensENSP0000041551669.540264.1762lepisosteus_oculatusENSLOCP0000000542786.842180.1435
ENSG00000184937homo_sapiensENSP0000041551661.302750.5747clupea_harengusENSCHAP0000005091967.226955.4622
ENSG00000184937homo_sapiensENSP0000041551668.199260.3448clupea_harengusENSCHAP0000005934573.25164.8148
ENSG00000184937homo_sapiensENSP0000041551663.601554.2146danio_rerioENSDARP0000012136480.582568.6893
ENSG00000184937homo_sapiensENSP0000041551668.199261.8774danio_rerioENSDARP0000002917484.964277.0883
ENSG00000184937homo_sapiensENSP0000041551669.540262.8353carassius_auratusENSCARP0000004029679.08571.4597
ENSG00000184937homo_sapiensENSP0000041551663.601554.7893carassius_auratusENSCARP0000010341181.572570.2703
ENSG00000184937homo_sapiensENSP0000041551668.965562.069carassius_auratusENSCARP0000009287782.949374.6544
ENSG00000184937homo_sapiensENSP0000041551669.540262.8353carassius_auratusENSCARP0000001148379.08571.4597
ENSG00000184937homo_sapiensENSP0000041551670.114963.2184carassius_auratusENSCARP0000012297682.432474.3243
ENSG00000184937homo_sapiensENSP0000041551663.4154.5977carassius_auratusENSCARP0000012121681.527170.197
ENSG00000184937homo_sapiensENSP0000041551659.195451.9157astyanax_mexicanusENSAMXP0000003059179.028169.3095
ENSG00000184937homo_sapiensENSP0000041551667.624560.9195astyanax_mexicanusENSAMXP0000004818585.060276.6265
ENSG00000184937homo_sapiensENSP0000041551659.578550.9579ictalurus_punctatusENSIPUP0000001903478.337567.0025
ENSG00000184937homo_sapiensENSP0000041551668.965561.6858ictalurus_punctatusENSIPUP0000001503786.124477.0335
ENSG00000184937homo_sapiensENSP0000041551663.218453.8314esox_luciusENSELUP0000002444077.102865.6542
ENSG00000184937homo_sapiensENSP0000041551670.689764.3678esox_luciusENSELUP0000007662979.184572.103
ENSG00000184937homo_sapiensENSP0000041551668.199261.1111electrophorus_electricusENSEEEP0000001461886.198577.2397
ENSG00000184937homo_sapiensENSP0000041551660.153351.1494electrophorus_electricusENSEEEP0000000100278.894567.0854
ENSG00000184937homo_sapiensENSP0000041551660.153351.5326oncorhynchus_kisutchENSOKIP0000510949865.416756.0417
ENSG00000184937homo_sapiensENSP0000041551664.559459.7701oncorhynchus_kisutchENSOKIP0000511074085.10178.7879
ENSG00000184937homo_sapiensENSP0000041551642.911935.249oncorhynchus_kisutchENSOKIP0000510938472.258159.3548
ENSG00000184937homo_sapiensENSP0000041551669.157161.8774oncorhynchus_kisutchENSOKIP0000504378382.798274.0826
ENSG00000184937homo_sapiensENSP0000041551664.75159.7701oncorhynchus_mykissENSOMYP0000000056585.786879.1878
ENSG00000184937homo_sapiensENSP0000041551654.980845.7854oncorhynchus_mykissENSOMYP0000007470261.853451.5086
ENSG00000184937homo_sapiensENSP0000041551653.831444.0613oncorhynchus_mykissENSOMYP0000012439253.62643.8931
ENSG00000184937homo_sapiensENSP0000041551665.134156.5134oncorhynchus_mykissENSOMYP0000011017676.233266.1435
ENSG00000184937homo_sapiensENSP0000041551665.325756.705salmo_salarENSSSAP0000014081972.553262.9787
ENSG00000184937homo_sapiensENSP0000041551665.708860.1533salmo_salarENSSSAP0000003078279.953473.1935
ENSG00000184937homo_sapiensENSP0000041551665.134156.5134salmo_salarENSSSAP0000017089677.272767.0455
ENSG00000184937homo_sapiensENSP0000041551668.965561.8774salmo_salarENSSSAP0000000994473.92266.3244
ENSG00000184937homo_sapiensENSP0000041551665.134156.705salmo_truttaENSSTUP0000006413477.272767.2727
ENSG00000184937homo_sapiensENSP0000041551666.475160.3448salmo_truttaENSSTUP0000004836985.25877.3956
ENSG00000184937homo_sapiensENSP0000041551630.076624.9042salmo_truttaENSSTUP0000009838371.363659.0909
ENSG00000184937homo_sapiensENSP0000041551656.513450.9579salmo_truttaENSSTUP0000003569479.088571.3137
ENSG00000184937homo_sapiensENSP0000041551660.536451.7241gadus_morhuaENSGMOP0000001315970.066559.867
ENSG00000184937homo_sapiensENSP0000041551668.965560.1533gadus_morhuaENSGMOP0000004374480.536970.2461
ENSG00000184937homo_sapiensENSP0000041551663.601556.8966fundulus_heteroclitusENSFHEP0000002043677.209369.0698
ENSG00000184937homo_sapiensENSP0000041551662.452153.6398fundulus_heteroclitusENSFHEP0000003337677.068666.1939
ENSG00000184937homo_sapiensENSP0000041551662.260552.8736poecilia_reticulataENSPREP0000002024366.326556.3265
ENSG00000184937homo_sapiensENSP0000041551650.957944.0613poecilia_reticulataENSPREP0000000181574.719164.6067
ENSG00000184937homo_sapiensENSP0000041551661.685852.2989xiphophorus_maculatusENSXMAP0000001425476.303364.6919
ENSG00000184937homo_sapiensENSP0000041551667.241459.387xiphophorus_maculatusENSXMAP0000000516881.818272.2611
ENSG00000184937homo_sapiensENSP0000041551659.961751.5326oryzias_latipesENSORLP0000003880174.880464.3541
ENSG00000184937homo_sapiensENSP0000041551668.773961.1111oryzias_latipesENSORLP0000001555182.528773.3333
ENSG00000184937homo_sapiensENSP0000041551657.854449.6169cyclopterus_lumpusENSCLMP0000500504974.93864.268
ENSG00000184937homo_sapiensENSP0000041551667.049859.5785cyclopterus_lumpusENSCLMP0000502839581.585172.4942
ENSG00000184937homo_sapiensENSP0000041551662.06954.2146oreochromis_niloticusENSONIP0000000697076.777367.0616
ENSG00000184937homo_sapiensENSP0000041551667.624559.9617oreochromis_niloticusENSONIP0000001389574.159765.7563
ENSG00000184937homo_sapiensENSP0000041551662.452154.7893haplochromis_burtoniENSHBUP0000001494976.525867.1361
ENSG00000184937homo_sapiensENSP0000041551669.157161.6858haplochromis_burtoniENSHBUP0000000134381.674272.8507
ENSG00000184937homo_sapiensENSP0000041551662.452154.7893astatotilapia_callipteraENSACLP0000001161676.525867.1361
ENSG00000184937homo_sapiensENSP0000041551659.770151.341astatotilapia_callipteraENSACLP000000210826555.8333
ENSG00000184937homo_sapiensENSP0000041551669.540262.069sparus_aurataENSSAUP0001001598273.481865.587
ENSG00000184937homo_sapiensENSP0000041551663.793155.9387sparus_aurataENSSAUP0001002628069.811361.2159
ENSG00000184937homo_sapiensENSP0000041551664.559455.9387lates_calcariferENSLCAP0001000991370.062460.7069
ENSG00000184937homo_sapiensENSP0000041551668.199260.9195lates_calcariferENSLCAP0001003811180.361271.7833
ENSG00000184937homo_sapiensENSP0000041551674.329568.5824xenopus_tropicalisENSXETP0000001792490.023283.0626
ENSG00000184937homo_sapiensENSP0000041551661.877457.0881chrysemys_picta_belliiENSCPBP0000002574183.247476.8041
ENSG00000184937homo_sapiensENSP0000041551675.287471.6475sphenodon_punctatusENSSPUP0000000592194.244689.6882
ENSG00000184937homo_sapiensENSP0000041551669.348766.092crocodylus_porosusENSCPRP0000500947091.878287.5635
ENSG00000184937homo_sapiensENSP0000041551651.149448.8506laticauda_laticaudataENSLLTP0000001650792.06987.931
ENSG00000184937homo_sapiensENSP0000041551667.816164.9425notechis_scutatusENSNSUP0000001640589.620385.8228
ENSG00000184937homo_sapiensENSP0000041551667.624564.751pseudonaja_textilisENSPTXP0000000421089.367185.5696
ENSG00000184937homo_sapiensENSP0000041551675.095872.0307anas_platyrhynchos_platyrhynchosENSAPLP0000002493794.68690.8213
ENSG00000184937homo_sapiensENSP0000041551681.034577.2031gallus_gallusENSGALP0001003503968.446665.2104
ENSG00000184937homo_sapiensENSP0000041551643.869740.613meleagris_gallopavoENSMGAP0000000095667.751562.7219
ENSG00000184937homo_sapiensENSP0000041551675.670572.6054serinus_canariaENSSCAP0000001038994.724290.8873
ENSG00000184937homo_sapiensENSP0000041551675.862172.7969parus_majorENSPMJP0000000254394.96491.1271
ENSG00000184937homo_sapiensENSP0000041551660.919556.705anolis_carolinensisENSACAP0000000245372.768967.7346
ENSG00000184937homo_sapiensENSP0000041551644.63637.3563neolamprologus_brichardiENSNBRP0000000131841.756334.9462
ENSG00000184937homo_sapiensENSP0000041551657.279750.5747neolamprologus_brichardiENSNBRP0000000919876.470667.5192
ENSG00000184937homo_sapiensENSP0000041551668.390865.3257naja_najaENSNNAP0000002275390.379786.3291
ENSG00000184937homo_sapiensENSP0000041551673.946469.5402podarcis_muralisENSPMRP0000000071676.739672.167
ENSG00000184937homo_sapiensENSP0000041551675.095872.0307geospiza_fortisENSGFOP0000001888994.004890.1679
ENSG00000184937homo_sapiensENSP0000041551675.095872.0307taeniopygia_guttataENSTGUP0000001949994.68690.8213
ENSG00000184937homo_sapiensENSP0000041551670.306563.41erpetoichthys_calabaricusENSECRP0000000650388.221279.5673
ENSG00000184937homo_sapiensENSP0000041551661.494351.9157kryptolebias_marmoratusENSKMAP0000001483975.529463.7647
ENSG00000184937homo_sapiensENSP0000041551667.241459.387kryptolebias_marmoratusENSKMAP0000001013879.054169.8198
ENSG00000184937homo_sapiensENSP0000041551674.712672.0307salvator_merianaeENSSMRP0000000165593.301489.9522
ENSG00000184937homo_sapiensENSP0000041551668.773960.728oryzias_javanicusENSOJAP0000000420782.528772.8736
ENSG00000184937homo_sapiensENSP0000041551659.961752.1073oryzias_javanicusENSOJAP0000002505374.701764.9165
ENSG00000184937homo_sapiensENSP0000041551660.72853.6398amphilophus_citrinellusENSACIP0000000725475.837366.9856
ENSG00000184937homo_sapiensENSP0000041551668.773961.1111amphilophus_citrinellusENSACIP0000000746881.221772.1719
ENSG00000184937homo_sapiensENSP0000041551659.38750.9579dicentrarchus_labraxENSDLAP0000507076073.459763.0332
ENSG00000184937homo_sapiensENSP0000041551668.582460.728dicentrarchus_labraxENSDLAP0000505276973.360764.959
ENSG00000184937homo_sapiensENSP0000041551657.662848.4674amphiprion_perculaENSAPEP0000001086272.881461.2591
ENSG00000184937homo_sapiensENSP0000041551668.007760.728amphiprion_perculaENSAPEP0000001068284.123275.1185
ENSG00000184937homo_sapiensENSP0000041551669.348761.6858oryzias_sinensisENSOSIP0000000111282.648473.516
ENSG00000184937homo_sapiensENSP0000041551660.344851.9157oryzias_sinensisENSOSIP000000276917564.5238
ENSG00000184937homo_sapiensENSP0000041551674.904272.0307pelodiscus_sinensisENSPSIP0000001540394.216990.6024
ENSG00000184937homo_sapiensENSP0000041551641.187739.0805gopherus_evgoodeiENSGEVP0000500240192.672487.931
ENSG00000184937homo_sapiensENSP0000041551670.689768.3908chelonoidis_abingdoniiENSCABP0000001705794.373491.3043
ENSG00000184937homo_sapiensENSP0000041551662.835354.2146seriola_dumeriliENSSDUP0000002858476.81566.2763
ENSG00000184937homo_sapiensENSP0000041551668.965561.8774seriola_dumeriliENSSDUP0000000597383.526774.942
ENSG00000184937homo_sapiensENSP0000041551662.835354.7893cottoperca_gobioENSCGOP0000000625576.995367.1361
ENSG00000184937homo_sapiensENSP0000041551664.942558.6207cottoperca_gobioENSCGOP0000000071480.331872.5118
ENSG00000184937homo_sapiensENSP0000041551675.670572.6054anser_brachyrhynchusENSABRP0000002106094.724290.8873
ENSG00000184937homo_sapiensENSP0000041551662.06954.2146gasterosteus_aculeatusENSGACP0000002114477.884668.0288
ENSG00000184937homo_sapiensENSP0000041551657.471350.1916gasterosteus_aculeatusENSGACP0000000431572.815563.5922
ENSG00000184937homo_sapiensENSP0000041551635.057529.1188cynoglossus_semilaevisENSCSEP0000002256960.39650.165
ENSG00000184937homo_sapiensENSP0000041551666.666758.4291cynoglossus_semilaevisENSCSEP0000003304929.048425.4591
ENSG00000184937homo_sapiensENSP0000041551665.900457.2797poecilia_formosaENSPFOP0000001067574.620464.859
ENSG00000184937homo_sapiensENSP0000041551661.877452.4904poecilia_formosaENSPFOP0000001719576.540364.9289
ENSG00000184937homo_sapiensENSP0000041551668.007760.5364myripristis_murdjanENSMMDP0000502395682.750673.6597
ENSG00000184937homo_sapiensENSP0000041551665.134156.5134myripristis_murdjanENSMMDP0000500613179.254168.7646
ENSG00000184937homo_sapiensENSP0000041551661.302753.6398sander_luciopercaENSSLUP0000002746778.239668.4597
ENSG00000184937homo_sapiensENSP0000041551669.157161.4943sander_luciopercaENSSLUP0000006116384.149274.8252
ENSG00000184937homo_sapiensENSP0000041551673.563270.6897strigops_habroptilaENSSHBP0000501340391.86688.2775
ENSG00000184937homo_sapiensENSP0000041551635.057531.0345amphiprion_ocellarisENSAOCP0000000583175.619866.9421
ENSG00000184937homo_sapiensENSP0000041551663.218454.7893amphiprion_ocellarisENSAOCP0000000729577.464867.1361
ENSG00000184937homo_sapiensENSP0000041551633.90830.8429amphiprion_ocellarisENSAOCP0000000279993.650885.1852
ENSG00000184937homo_sapiensENSP0000041551670.881268.3908terrapene_carolina_triunguisENSTMTP0000000025094.629291.3043
ENSG00000184937homo_sapiensENSP0000041551668.773961.4943hucho_huchoENSHHUP0000000974270.808763.3136
ENSG00000184937homo_sapiensENSP0000041551617.816114.9425hucho_huchoENSHHUP0000002268958.860849.3671
ENSG00000184937homo_sapiensENSP0000041551621.839116.8582hucho_huchoENSHHUP0000002153059.067445.5959
ENSG00000184937homo_sapiensENSP0000041551613.601510.1533hucho_huchoENSHHUP0000006803873.958355.2083
ENSG00000184937homo_sapiensENSP0000041551619.540215.7088hucho_huchoENSHHUP0000001221161.445849.3976
ENSG00000184937homo_sapiensENSP0000041551667.43362.2605hucho_huchoENSHHUP0000005506785.853779.2683
ENSG00000184937homo_sapiensENSP0000041551613.793112.2605hucho_huchoENSHHUP000000065817264
ENSG00000184937homo_sapiensENSP0000041551660.919552.1073betta_splendensENSBSLP0000004412477.372366.18
ENSG00000184937homo_sapiensENSP0000041551668.390861.3027betta_splendensENSBSLP0000004056880.224771.9101
ENSG00000184937homo_sapiensENSP0000041551662.643753.2567pygocentrus_nattereriENSPNAP0000003219180.740768.642
ENSG00000184937homo_sapiensENSP0000041551668.965562.2605pygocentrus_nattereriENSPNAP0000000054686.956578.5024
ENSG00000184937homo_sapiensENSP0000041551669.157162.069anabas_testudineusENSATEP0000004916782.045573.6364
ENSG00000184937homo_sapiensENSP0000041551661.685853.6398anabas_testudineusENSATEP0000003267977.033566.9856
ENSG00000184937homo_sapiensENSP0000041551613.60158.04598saccharomyces_cerevisiaeYLR375W20.699712.2449
ENSG00000184937homo_sapiensENSP0000041551618.773910.9195saccharomyces_cerevisiaeYDL048C2011.6327
ENSG00000184937homo_sapiensENSP0000041551662.835354.4061seriola_lalandi_dorsalisENSSLDP0000003353776.81566.5105
ENSG00000184937homo_sapiensENSP0000041551668.965561.8774seriola_lalandi_dorsalisENSSLDP0000000981683.526774.942
ENSG00000184937homo_sapiensENSP0000041551630.842926.0536labrus_bergyltaENSLBEP0000000522171.87560.7143
ENSG00000184937homo_sapiensENSP0000041551645.210736.3985labrus_bergyltaENSLBEP0000001958771.732557.7508
ENSG00000184937homo_sapiensENSP0000041551663.218453.2567labrus_bergyltaENSLBEP0000000264077.283465.1054
ENSG00000184937homo_sapiensENSP0000041551656.896650.3831pundamilia_nyerereiENSPNYP0000002388975.959167.2634
ENSG00000184937homo_sapiensENSP0000041551663.4157.0881pundamilia_nyerereiENSPNYP0000001198884.223975.827
ENSG00000184937homo_sapiensENSP0000041551661.877453.6398mastacembelus_armatusENSMAMP0000003022375.64465.5738
ENSG00000184937homo_sapiensENSP0000041551669.348762.069mastacembelus_armatusENSMAMP0000002221279.735771.3656
ENSG00000184937homo_sapiensENSP0000041551663.4155.364stegastes_partitusENSSPAP0000000666477.699567.8404
ENSG00000184937homo_sapiensENSP0000041551664.75157.0881stegastes_partitusENSSPAP0000002339578.240768.9815
ENSG00000184937homo_sapiensENSP0000041551631.609223.5632oncorhynchus_tshawytschaENSOTSP0000503615062.264246.4151
ENSG00000184937homo_sapiensENSP0000041551666.283560.728oncorhynchus_tshawytschaENSOTSP0000502496185.221778.0788
ENSG00000184937homo_sapiensENSP0000041551669.731862.2605oncorhynchus_tshawytschaENSOTSP0000508210679.130470.6522
ENSG00000184937homo_sapiensENSP0000041551634.865929.6935oncorhynchus_tshawytschaENSOTSP0000503393373.092462.249
ENSG00000184937homo_sapiensENSP0000041551664.559457.6628acanthochromis_polyacanthusENSAPOP0000002629183.004974.1379
ENSG00000184937homo_sapiensENSP0000041551662.835354.5977acanthochromis_polyacanthusENSAPOP0000002710676.995366.9014
ENSG00000184937homo_sapiensENSP0000041551675.287472.2222aquila_chrysaetos_chrysaetosENSACCP0002001502994.927591.0628
ENSG00000184937homo_sapiensENSP0000041551655.938746.1686nothobranchius_furzeriENSNFUP0001501604168.867956.8396
ENSG00000184937homo_sapiensENSP0000041551667.43358.8123nothobranchius_furzeriENSNFUP0001504117371.690462.5255
ENSG00000184937homo_sapiensENSP0000041551667.816160.1533cyprinodon_variegatusENSCVAP0000000178682.90473.5363
ENSG00000184937homo_sapiensENSP0000041551660.919551.7241cyprinodon_variegatusENSCVAP0000003074875.534464.133
ENSG00000184937homo_sapiensENSP0000041551668.773962.4521denticeps_clupeoidesENSDCDP0000003484584.470676.7059
ENSG00000184937homo_sapiensENSP0000041551664.942554.9808denticeps_clupeoidesENSDCDP0000001153880.906968.4964
ENSG00000184937homo_sapiensENSP0000041551668.582460.9195larimichthys_croceaENSLCRP0000505256976.170267.6596
ENSG00000184937homo_sapiensENSP0000041551663.026855.1724larimichthys_croceaENSLCRP0000501321377.594367.9245
ENSG00000184937homo_sapiensENSP0000041551667.241457.4713takifugu_rubripesENSTRUP0000006284279.591868.0272
ENSG00000184937homo_sapiensENSP0000041551660.153350.1916takifugu_rubripesENSTRUP0000001610075.299862.8297
ENSG00000184937homo_sapiensENSP0000041551650.191645.2107ficedula_albicollisENSFALP0000001711456.465550.8621
ENSG00000184937homo_sapiensENSP0000041551663.026856.705hippocampus_comesENSHCOP0000001270279.086571.1538
ENSG00000184937homo_sapiensENSP0000041551661.302752.8736hippocampus_comesENSHCOP0000002511975.117464.7887
ENSG00000184937homo_sapiensENSP0000041551663.984754.9808cyprinus_carpio_carpioENSCCRP0000006086181.662670.1712
ENSG00000184937homo_sapiensENSP0000041551662.260554.023cyprinus_carpio_carpioENSCCRP0000010021477.38167.1429
ENSG00000184937homo_sapiensENSP0000041551669.540262.8353cyprinus_carpio_carpioENSCCRP0000009235980.309772.5664
ENSG00000184937homo_sapiensENSP0000041551669.348762.6437cyprinus_carpio_carpioENSCCRP0000006036077.021369.5745
ENSG00000184937homo_sapiensENSP0000041551680.459876.6283coturnix_japonicaENSCJPP0000501892068.627465.3595
ENSG00000184937homo_sapiensENSP0000041551661.685852.4904poecilia_latipinnaENSPLAP0000002387376.303364.9289
ENSG00000184937homo_sapiensENSP0000041551668.007759.9617poecilia_latipinnaENSPLAP0000000819279.775370.3371
ENSG00000184937homo_sapiensENSP0000041551660.153351.5326sinocyclocheilus_grahamiENSSGRP0000009121980.10268.6225
ENSG00000184937homo_sapiensENSP0000041551660.153354.2146sinocyclocheilus_grahamiENSSGRP0000006408077.339969.7044
ENSG00000184937homo_sapiensENSP0000041551668.582461.8774sinocyclocheilus_grahamiENSSGRP0000007619286.265177.8313
ENSG00000184937homo_sapiensENSP0000041551662.06954.023sinocyclocheilus_grahamiENSSGRP0000010773081.612171.0327
ENSG00000184937homo_sapiensENSP0000041551661.494354.2146maylandia_zebraENSMZEP0000501594976.794367.7033
ENSG00000184937homo_sapiensENSP0000041551669.157161.1111maylandia_zebraENSMZEP0000501681281.674272.1719
ENSG00000184937homo_sapiensENSP0000041551660.72850.9579tetraodon_nigroviridisENSTNIP0000001680876.201963.9423
ENSG00000184937homo_sapiensENSP0000041551663.4155.364tetraodon_nigroviridisENSTNIP0000001061482.13471.7122
ENSG00000184937homo_sapiensENSP0000041551664.176257.8544paramormyrops_kingsleyaeENSPKIP0000000774279.572471.734
ENSG00000184937homo_sapiensENSP0000041551669.540262.6437scleropages_formosusENSSFOP0001506574274.233166.8712
ENSG00000184937homo_sapiensENSP0000041551671.647567.6245leptobrachium_leishanenseENSLLEP0000004030389.688284.6523
ENSG00000184937homo_sapiensENSP0000041551663.218454.5977scophthalmus_maximusENSSMAP0000000388677.464866.9014
ENSG00000184937homo_sapiensENSP0000041551666.858259.9617scophthalmus_maximusENSSMAP0000005759674.892767.1674
ENSG00000184937homo_sapiensENSP0000041551669.540261.6858oryzias_melastigmaENSOMEP0000001150382.876773.516
ENSG00000184937homo_sapiensENSP0000041551659.961751.9157oryzias_melastigmaENSOMEP0000000303174.701764.6778

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0000122acts_upstream_of_or_within negative regulation of transcription by RNA polymerase II2IDA,IMPHomo_sapiens(9606)Process
GO:0000976enables transcription cis-regulatory region binding1IDAHomo_sapiens(9606)Function
GO:0000978enables RNA polymerase II cis-regulatory region sequence-specific DNA binding2IBA,IDAHomo_sapiens(9606)Function
GO:0000981enables DNA-binding transcription factor activity, RNA polymerase II-specific1IBAHomo_sapiens(9606)Function
GO:0001228enables DNA-binding transcription activator activity, RNA polymerase II-specific2IDA,ISSHomo_sapiens(9606)Function
GO:0001570involved_in vasculogenesis1ISSHomo_sapiens(9606)Process
GO:0001657involved_in ureteric bud development1ISSHomo_sapiens(9606)Process
GO:0001658involved_in branching involved in ureteric bud morphogenesis1IGIHomo_sapiens(9606)Process
GO:0001822involved_in kidney development1IGIHomo_sapiens(9606)Process
GO:0003156involved_in regulation of animal organ formation1ISSHomo_sapiens(9606)Process
GO:0003700enables DNA-binding transcription factor activity2ISS,NASHomo_sapiens(9606)Function
GO:0003723enables RNA binding1IEAHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005634located_in nucleus1IDAHomo_sapiens(9606)Component
GO:0005654located_in nucleoplasm1IDAHomo_sapiens(9606)Component
GO:0005730located_in nucleolus1IEAHomo_sapiens(9606)Component
GO:0005737located_in cytoplasm1ISSHomo_sapiens(9606)Component
GO:0005829located_in cytosol1IDAHomo_sapiens(9606)Component
GO:0006355involved_in regulation of DNA-templated transcription2ISS,NASHomo_sapiens(9606)Process
GO:0006357involved_in regulation of transcription by RNA polymerase II2IBA,ISSHomo_sapiens(9606)Process
GO:0007281involved_in germ cell development1ISSHomo_sapiens(9606)Process
GO:0007356involved_in thorax and anterior abdomen determination1ISSHomo_sapiens(9606)Process
GO:0007507involved_in heart development1IGIHomo_sapiens(9606)Process
GO:0007530involved_in sex determination1IDAHomo_sapiens(9606)Process
GO:0008270enables zinc ion binding1IDAHomo_sapiens(9606)Function
GO:0008285involved_in negative regulation of cell population proliferation2IBA,IDAHomo_sapiens(9606)Process
GO:0008380involved_in RNA splicing1ISSHomo_sapiens(9606)Process
GO:0008406involved_in gonad development1ISSHomo_sapiens(9606)Process
GO:0008584involved_in male gonad development1IEPHomo_sapiens(9606)Process
GO:0009888involved_in tissue development1ISSHomo_sapiens(9606)Process
GO:0010385enables double-stranded methylated DNA binding1IDAHomo_sapiens(9606)Function
GO:0010628involved_in positive regulation of gene expression1IMPHomo_sapiens(9606)Process
GO:0016607located_in nuclear speck1IDAHomo_sapiens(9606)Component
GO:0030308involved_in negative regulation of cell growth1IDAHomo_sapiens(9606)Process
GO:0030325involved_in adrenal gland development1IGIHomo_sapiens(9606)Process
GO:0030539involved_in male genitalia development1ISSHomo_sapiens(9606)Process
GO:0030855involved_in epithelial cell differentiation1ISSHomo_sapiens(9606)Process
GO:0032835involved_in glomerulus development1IGIHomo_sapiens(9606)Process
GO:0032836involved_in glomerular basement membrane development1IMPHomo_sapiens(9606)Process
GO:0035802involved_in adrenal cortex formation1ISSHomo_sapiens(9606)Process
GO:0043010involved_in camera-type eye development1ISSHomo_sapiens(9606)Process
GO:0043066involved_in negative regulation of apoptotic process2IBA,IGIHomo_sapiens(9606)Process
GO:0043565enables sequence-specific DNA binding1IDAHomo_sapiens(9606)Function
GO:0044729enables hemi-methylated DNA-binding1IDAHomo_sapiens(9606)Function
GO:0045892involved_in negative regulation of DNA-templated transcription1IDAHomo_sapiens(9606)Process
GO:0045893involved_in positive regulation of DNA-templated transcription2IDA,IGIHomo_sapiens(9606)Process
GO:0045944involved_in positive regulation of transcription by RNA polymerase II1IDAHomo_sapiens(9606)Process
GO:0060231involved_in mesenchymal to epithelial transition1ISSHomo_sapiens(9606)Process
GO:0060421involved_in positive regulation of heart growth1ISSHomo_sapiens(9606)Process
GO:0060539involved_in diaphragm development1ISSHomo_sapiens(9606)Process
GO:0060923involved_in cardiac muscle cell fate commitment1ISSHomo_sapiens(9606)Process
GO:0061032involved_in visceral serous pericardium development1IGIHomo_sapiens(9606)Process
GO:0070742enables C2H2 zinc finger domain binding1IPIHomo_sapiens(9606)Function
GO:0071320involved_in cellular response to cAMP1IEPHomo_sapiens(9606)Process
GO:0071371involved_in cellular response to gonadotropin stimulus1IDAHomo_sapiens(9606)Process
GO:0072075involved_in metanephric mesenchyme development1ISSHomo_sapiens(9606)Process
GO:0072112involved_in podocyte differentiation1ISSHomo_sapiens(9606)Process
GO:0072166involved_in posterior mesonephric tubule development1ISSHomo_sapiens(9606)Process
GO:0072207involved_in metanephric epithelium development1IEPHomo_sapiens(9606)Process
GO:0072284involved_in metanephric S-shaped body morphogenesis1IGIHomo_sapiens(9606)Process
GO:0072302involved_in negative regulation of metanephric glomerular mesangial cell proliferation1ISSHomo_sapiens(9606)Process
GO:1902895involved_in positive regulation of miRNA transcription1IMPHomo_sapiens(9606)Process
GO:1905643acts_upstream_of positive regulation of DNA methylation1IMPHomo_sapiens(9606)Process
GO:2000020involved_in positive regulation of male gonad development1ISSHomo_sapiens(9606)Process
GO:2000195involved_in negative regulation of female gonad development1ISSHomo_sapiens(9606)Process
GO:2001076involved_in positive regulation of metanephric ureteric bud development1ISSHomo_sapiens(9606)Process

Expression