RBP Type	Canonical_RBPs
Diseases	N.A.
Drug	N.A.
Main interacting RNAs	N.A.
Moonlighting functions	Transmemebrane
Localizations	N.A.
BulkPerturb-seq	N.A.

Ensembl ID	ENSG00000181562	Gene ID	10876	Accession	16978
Symbol	EDDM3A	Alias	EP3A;HE3A;RAM1;FAM12A;HE3ALPHA;HE3-ALPHA	Full Name	epididymal protein 3A
Status	Confidence	Length	2494 bases	Strand	Plus strand
Position	14 : 20745887 - 20748380	RNA binding domain	RnaseA
Summary	Testicular sperm are morphologically differentiated but are not progressively motile nor able to fertilize an egg. Post-testicular maturation requires exposure of spermatozoa to the microenvironment of the epididymal lumen. Spermatozoa undergo extensive changes in the epididymis, including enzymatic modifications, loss of pre-existing components and addition of new glycoproteins from epididymal secretions. These modifying proteins and enzymes are synthesized by epithelial cells lining the epididymal duct and secreted apically into the lumen, where they come into contact with, and may be absorbed onto, the sperm membranes. The proteins encoded by the genes in this cluster are synthesized and secreted by epididymal epithelial cells. [provided by RefSeq, Jul 2008]

Protein	Domain	Pfam ID	E-value	Domain number
ENSP00000315098	RnaseA	PF00074	1e-05	1

Pubmed ID	Full Name	Cell	Author	Time	Doi

Pubmed ID	Title	Author	Time	Journal

Name	Transcript ID	bp	Protein	Translation ID
EDDM3A-201	ENST00000326842	932	147aa	ENSP00000315098

Pathway ID	Pathway Name	Source

ensgID	Trait	pValue	Pubmed ID
23088	Body Height	9.0710000E-006	-
23134	Body Height	7.7010000E-006	-
23562	Body Height	5.7560000E-005	-
23623	Body Height	4.9990000E-005	-
23866	Waist-Hip Ratio	9.7210000E-005	-

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
ENSG00000181562	homo_sapiens	ENSP00000314810	78.9116	68.7075	homo_sapiens	ENSP00000315098	78.9116	68.7075

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
ENSG00000181562	homo_sapiens	ENSP00000315098	99.3197	98.6395	pan_paniscus	ENSPPAP00000000066	99.3197	98.6395
ENSG00000181562	homo_sapiens	ENSP00000315098	97.9592	96.5986	pongo_abelii	ENSPPYP00000006343	97.9592	96.5986
ENSG00000181562	homo_sapiens	ENSP00000315098	99.3197	98.6395	pan_troglodytes	ENSPTRP00000010356	99.3197	98.6395
ENSG00000181562	homo_sapiens	ENSP00000315098	99.3197	98.6395	gorilla_gorilla	ENSGGOP00000016339	99.3197	98.6395
ENSG00000181562	homo_sapiens	ENSP00000315098	59.1837	40.8163	sarcophilus_harrisii	ENSSHAP00000006973	59.589	41.0959
ENSG00000181562	homo_sapiens	ENSP00000315098	55.7823	36.7347	notamacropus_eugenii	ENSMEUP00000013749	58.5714	38.5714
ENSG00000181562	homo_sapiens	ENSP00000315098	70.7483	51.0204	choloepus_hoffmanni	ENSCHOP00000010057	71.2329	51.3699
ENSG00000181562	homo_sapiens	ENSP00000315098	53.7415	38.7755	dasypus_novemcinctus	ENSDNOP00000026324	72.4771	52.2936
ENSG00000181562	homo_sapiens	ENSP00000315098	68.0272	50.3401	erinaceus_europaeus	ENSEEUP00000004491	68.4931	50.6849
ENSG00000181562	homo_sapiens	ENSP00000315098	53.7415	43.5374	echinops_telfairi	ENSETEP00000009112	54.4828	44.1379
ENSG00000181562	homo_sapiens	ENSP00000315098	94.5578	88.4354	macaca_fascicularis	ENSMFAP00000046901	94.5578	88.4354
ENSG00000181562	homo_sapiens	ENSP00000315098	94.5578	88.4354	macaca_mulatta	ENSMMUP00000071965	94.5578	88.4354
ENSG00000181562	homo_sapiens	ENSP00000315098	93.8775	87.7551	papio_anubis	ENSPANP00000009282	93.8775	87.7551
ENSG00000181562	homo_sapiens	ENSP00000315098	66.6667	48.9796	vulpes_vulpes	ENSVVUP00000012288	60.4938	44.4444
ENSG00000181562	homo_sapiens	ENSP00000315098	68.0272	49.6599	mus_spretus	MGP_SPRETEiJ_P0038223	67.1141	48.9933
ENSG00000181562	homo_sapiens	ENSP00000315098	72.7891	53.7415	equus_asinus	ENSEASP00005040517	73.7931	54.4828
ENSG00000181562	homo_sapiens	ENSP00000315098	61.9048	44.2177	loxodonta_africana	ENSLAFP00000027521	62.3288	44.5205
ENSG00000181562	homo_sapiens	ENSP00000315098	64.6258	48.2993	loxodonta_africana	ENSLAFP00000025435	65.0685	48.6301
ENSG00000181562	homo_sapiens	ENSP00000315098	71.4286	51.7007	panthera_leo	ENSPLOP00000011118	72.4138	52.4138
ENSG00000181562	homo_sapiens	ENSP00000315098	62.585	46.9388	ailuropoda_melanoleuca	ENSAMEP00000020961	56.7901	42.5926
ENSG00000181562	homo_sapiens	ENSP00000315098	70.068	51.0204	bos_indicus_hybrid	ENSBIXP00005037887	70.5479	51.3699
ENSG00000181562	homo_sapiens	ENSP00000315098	68.0272	49.6599	bos_indicus_hybrid	ENSBIXP00005016038	68.4931	50
ENSG00000181562	homo_sapiens	ENSP00000315098	67.3469	43.5374	oryctolagus_cuniculus	ENSOCUP00000022614	64.2857	41.5584
ENSG00000181562	homo_sapiens	ENSP00000315098	72.1088	54.4218	oryctolagus_cuniculus	ENSOCUP00000018170	72.1088	54.4218
ENSG00000181562	homo_sapiens	ENSP00000315098	72.7891	53.7415	equus_caballus	ENSECAP00000035668	73.7931	54.4828
ENSG00000181562	homo_sapiens	ENSP00000315098	66.6667	48.2993	canis_lupus_familiaris	ENSCAFP00845032249	67.5862	48.9655
ENSG00000181562	homo_sapiens	ENSP00000315098	71.4286	51.7007	panthera_pardus	ENSPPRP00000028086	72.4138	52.4138
ENSG00000181562	homo_sapiens	ENSP00000315098	74.8299	55.102	marmota_marmota_marmota	ENSMMMP00000016924	72.8477	53.6424
ENSG00000181562	homo_sapiens	ENSP00000315098	68.7075	51.0204	balaenoptera_musculus	ENSBMSP00010012166	69.1781	51.3699
ENSG00000181562	homo_sapiens	ENSP00000315098	72.1088	53.0612	felis_catus	ENSFCAP00000012770	73.1034	53.7931
ENSG00000181562	homo_sapiens	ENSP00000315098	59.1837	38.7755	monodelphis_domestica	ENSMODP00000034357	47.2826	30.9783
ENSG00000181562	homo_sapiens	ENSP00000315098	66.6667	47.619	bison_bison_bison	ENSBBBP00000001783	63.6364	45.4545
ENSG00000181562	homo_sapiens	ENSP00000315098	70.068	48.9796	monodon_monoceros	ENSMMNP00015013305	70.5479	49.3151
ENSG00000181562	homo_sapiens	ENSP00000315098	70.7483	50.3401	sus_scrofa	ENSSSCP00000025970	71.2329	50.6849
ENSG00000181562	homo_sapiens	ENSP00000315098	66.6667	45.5782	ovis_aries_rambouillet	ENSOARP00020017056	54.7486	37.4302
ENSG00000181562	homo_sapiens	ENSP00000315098	70.7483	50.3401	ovis_aries_rambouillet	ENSOARP00020017272	71.2329	50.6849
ENSG00000181562	homo_sapiens	ENSP00000315098	63.2653	43.5374	ochotona_princeps	ENSOPRP00000011957	64.1379	44.1379
ENSG00000181562	homo_sapiens	ENSP00000315098	70.068	49.6599	delphinapterus_leucas	ENSDLEP00000002311	58.8571	41.7143
ENSG00000181562	homo_sapiens	ENSP00000315098	67.3469	48.9796	mus_caroli	MGP_CAROLIEiJ_P0036503	66.443	48.3221
ENSG00000181562	homo_sapiens	ENSP00000315098	68.0272	48.9796	mus_musculus	ENSMUSP00000098210	67.1141	48.3221
ENSG00000181562	homo_sapiens	ENSP00000315098	74.8299	52.381	dipodomys_ordii	ENSDORP00000023132	72.3684	50.6579
ENSG00000181562	homo_sapiens	ENSP00000315098	68.0272	49.6599	mustela_putorius_furo	ENSMPUP00000018265	68.9655	50.3448
ENSG00000181562	homo_sapiens	ENSP00000315098	70.7483	49.6599	vicugna_pacos	ENSVPAP00000006855	71.2329	50
ENSG00000181562	homo_sapiens	ENSP00000315098	95.2381	88.4354	chlorocebus_sabaeus	ENSCSAP00000017651	95.2381	88.4354
ENSG00000181562	homo_sapiens	ENSP00000315098	71.4286	50.3401	camelus_dromedarius	ENSCDRP00005002558	71.9178	50.6849
ENSG00000181562	homo_sapiens	ENSP00000315098	70.7483	50.3401	panthera_tigris_altaica	ENSPTIP00000001586	71.7241	51.0345
ENSG00000181562	homo_sapiens	ENSP00000315098	65.9864	48.2993	rattus_norvegicus	ENSRNOP00000040734	67.8322	49.6503
ENSG00000181562	homo_sapiens	ENSP00000315098	66.6667	48.9796	rattus_norvegicus	ENSRNOP00000075575	65.3333	48
ENSG00000181562	homo_sapiens	ENSP00000315098	65.9864	37.415	peromyscus_maniculatus_bairdii	ENSPEMP00000033096	65.5405	37.1622
ENSG00000181562	homo_sapiens	ENSP00000315098	68.7075	44.898	peromyscus_maniculatus_bairdii	ENSPEMP00000014635	67.3333	44
ENSG00000181562	homo_sapiens	ENSP00000315098	68.0272	50.3401	mus_spicilegus	ENSMSIP00000023112	67.1141	49.6644
ENSG00000181562	homo_sapiens	ENSP00000315098	67.3469	48.9796	cricetulus_griseus_chok1gshd	ENSCGRP00001014058	66	48
ENSG00000181562	homo_sapiens	ENSP00000315098	70.068	53.0612	pteropus_vampyrus	ENSPVAP00000012795	70.5479	53.4247
ENSG00000181562	homo_sapiens	ENSP00000315098	70.7483	52.381	myotis_lucifugus	ENSMLUP00000012895	68.8742	50.9934
ENSG00000181562	homo_sapiens	ENSP00000315098	58.5034	37.415	vombatus_ursinus	ENSVURP00010026031	58.9041	37.6712
ENSG00000181562	homo_sapiens	ENSP00000315098	71.4286	53.0612	rhinolophus_ferrumequinum	ENSRFEP00010025716	71.9178	53.4247
ENSG00000181562	homo_sapiens	ENSP00000315098	67.3469	47.619	neovison_vison	ENSNVIP00000017006	68.2759	48.2759
ENSG00000181562	homo_sapiens	ENSP00000315098	67.3469	48.2993	neovison_vison	ENSNVIP00000016965	68.2759	48.9655
ENSG00000181562	homo_sapiens	ENSP00000315098	63.9456	46.2585	bos_taurus	ENSBTAP00000068181	66.6667	48.227
ENSG00000181562	homo_sapiens	ENSP00000315098	66.6667	48.2993	canis_lupus_dingo	ENSCAFP00020017993	60.4938	43.8272
ENSG00000181562	homo_sapiens	ENSP00000315098	73.4694	53.7415	sciurus_vulgaris	ENSSVLP00005002057	73.9726	54.1096
ENSG00000181562	homo_sapiens	ENSP00000315098	57.1429	38.0952	phascolarctos_cinereus	ENSPCIP00000039169	53.5032	35.6688
ENSG00000181562	homo_sapiens	ENSP00000315098	66.6667	46.2585	cervus_hanglu_yarkandensis	ENSCHYP00000021389	67.1233	46.5753
ENSG00000181562	homo_sapiens	ENSP00000315098	68.7075	50.3401	catagonus_wagneri	ENSCWAP00000008427	69.1781	50.6849
ENSG00000181562	homo_sapiens	ENSP00000315098	78.2313	62.585	otolemur_garnettii	ENSOGAP00000006953	78.2313	62.585
ENSG00000181562	homo_sapiens	ENSP00000315098	72.1088	53.7415	urocitellus_parryii	ENSUPAP00010002282	70.1987	52.3179
ENSG00000181562	homo_sapiens	ENSP00000315098	70.068	49.6599	moschus_moschiferus	ENSMMSP00000011160	70.5479	50
ENSG00000181562	homo_sapiens	ENSP00000315098	66.6667	46.2585	mus_pahari	MGP_PahariEiJ_P0084623	65.7718	45.6376

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0005515	enables protein binding	1	IPI	Homo_sapiens(9606)	Function
GO:0005615	located_in extracellular space	1	TAS	Homo_sapiens(9606)	Component
GO:0007321	involved_in sperm displacement	1	TAS	Homo_sapiens(9606)	Process