RBP Type	Canonical_RBPs
Diseases	N.A.
Drug	N.A.
Main interacting RNAs	N.A.
Moonlighting functions	Transmemebrane
Localizations	N.A.
BulkPerturb-seq	N.A.

Ensembl ID	ENSG00000181552	Gene ID	64184	Accession	19223
Symbol	EDDM3B	Alias	EP3B;HE3B;RAM2;FAM12B;HE3-BETA	Full Name	epididymal protein 3B
Status	Confidence	Length	2545 bases	Strand	Plus strand
Position	14 : 20768404 - 20770948	RNA binding domain	RnaseA
Summary	Testicular sperm are morphologically differentiated but are not progressively motile nor able to fertilize an egg. Post-testicular maturation requires exposure of spermatozoa to the microenvironment of the epididymal lumen. Spermatozoa undergo extensive changes in the epididymis, including enzymatic modifications, loss of pre-existing components and addition of new glycoproteins from epididymal secretions. These modifying proteins and enzymes are synthesized by epithelial cells lining the epididymal duct and secreted apically into the lumen, where they come into contact with, and may be absorbed onto, the sperm membranes. The proteins encoded by the genes in this cluster are synthesized and secreted by epididymal epithelial cells. [provided by RefSeq, Jul 2008]

Protein	Domain	Pfam ID	E-value	Domain number
ENSP00000314810	RnaseA	PF00074	1.2e-07	1

Pubmed ID	Full Name	Cell	Author	Time	Doi

Pubmed ID	Title	Author	Time	Journal

Name	Transcript ID	bp	Protein	Translation ID
EDDM3B-201	ENST00000326783	919	147aa	ENSP00000314810

Pathway ID	Pathway Name	Source

ensgID	Trait	pValue	Pubmed ID

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
ENSG00000181552	homo_sapiens	ENSP00000315098	78.9116	68.7075	homo_sapiens	ENSP00000314810	78.9116	68.7075

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
ENSG00000181552	homo_sapiens	ENSP00000314810	97.9592	95.2381	nomascus_leucogenys	ENSNLEP00000048104	97.9592	95.2381
ENSG00000181552	homo_sapiens	ENSP00000314810	97.9592	96.5986	nomascus_leucogenys	ENSNLEP00000047870	97.9592	96.5986
ENSG00000181552	homo_sapiens	ENSP00000314810	99.3197	98.6395	pan_paniscus	ENSPPAP00000019578	99.3197	98.6395
ENSG00000181552	homo_sapiens	ENSP00000314810	98.6395	97.2789	pongo_abelii	ENSPPYP00000006344	98.6395	97.2789
ENSG00000181552	homo_sapiens	ENSP00000314810	99.3197	98.6395	pan_troglodytes	ENSPTRP00000010357	99.3197	98.6395
ENSG00000181552	homo_sapiens	ENSP00000314810	98.6395	97.2789	gorilla_gorilla	ENSGGOP00000011273	98.6395	97.2789
ENSG00000181552	homo_sapiens	ENSP00000314810	61.2245	42.8571	sarcophilus_harrisii	ENSSHAP00000006973	61.6438	43.1507
ENSG00000181552	homo_sapiens	ENSP00000314810	58.5034	40.1361	notamacropus_eugenii	ENSMEUP00000013749	61.4286	42.1429
ENSG00000181552	homo_sapiens	ENSP00000314810	76.8708	55.102	choloepus_hoffmanni	ENSCHOP00000010057	77.3973	55.4795
ENSG00000181552	homo_sapiens	ENSP00000314810	57.8231	38.0952	dasypus_novemcinctus	ENSDNOP00000026324	77.9817	51.3761
ENSG00000181552	homo_sapiens	ENSP00000314810	70.7483	54.4218	erinaceus_europaeus	ENSEEUP00000004491	71.2329	54.7945
ENSG00000181552	homo_sapiens	ENSP00000314810	62.585	46.2585	echinops_telfairi	ENSETEP00000009112	63.4483	46.8966
ENSG00000181552	homo_sapiens	ENSP00000314810	97.2789	95.2381	cercocebus_atys	ENSCATP00000007691	97.2789	95.2381
ENSG00000181552	homo_sapiens	ENSP00000314810	96.5986	94.5578	macaca_fascicularis	ENSMFAP00000050115	96.5986	94.5578
ENSG00000181552	homo_sapiens	ENSP00000314810	96.5986	94.5578	macaca_mulatta	ENSMMUP00000002222	96.5986	94.5578
ENSG00000181552	homo_sapiens	ENSP00000314810	97.9592	95.9184	mandrillus_leucophaeus	ENSMLEP00000006823	97.9592	95.9184
ENSG00000181552	homo_sapiens	ENSP00000314810	71.4286	52.381	vulpes_vulpes	ENSVVUP00000012288	64.8148	47.5309
ENSG00000181552	homo_sapiens	ENSP00000314810	74.1497	54.4218	mus_spretus	MGP_SPRETEiJ_P0038223	73.1544	53.6913
ENSG00000181552	homo_sapiens	ENSP00000314810	78.2313	59.1837	equus_asinus	ENSEASP00005040517	79.3103	60
ENSG00000181552	homo_sapiens	ENSP00000314810	72.1088	50.3401	loxodonta_africana	ENSLAFP00000027521	72.6027	50.6849
ENSG00000181552	homo_sapiens	ENSP00000314810	73.4694	53.0612	loxodonta_africana	ENSLAFP00000025435	73.9726	53.4247
ENSG00000181552	homo_sapiens	ENSP00000314810	77.551	59.8639	panthera_leo	ENSPLOP00000011118	78.6207	60.6897
ENSG00000181552	homo_sapiens	ENSP00000314810	69.3878	53.7415	ailuropoda_melanoleuca	ENSAMEP00000020961	62.963	48.7654
ENSG00000181552	homo_sapiens	ENSP00000314810	74.8299	55.102	bos_indicus_hybrid	ENSBIXP00005037887	75.3425	55.4795
ENSG00000181552	homo_sapiens	ENSP00000314810	74.1497	55.102	bos_indicus_hybrid	ENSBIXP00005016038	74.6575	55.4795
ENSG00000181552	homo_sapiens	ENSP00000314810	76.8708	55.7823	oryctolagus_cuniculus	ENSOCUP00000022614	73.3766	53.2468
ENSG00000181552	homo_sapiens	ENSP00000314810	77.551	63.2653	oryctolagus_cuniculus	ENSOCUP00000018170	77.551	63.2653
ENSG00000181552	homo_sapiens	ENSP00000314810	78.2313	59.1837	equus_caballus	ENSECAP00000035668	79.3103	60
ENSG00000181552	homo_sapiens	ENSP00000314810	70.068	51.0204	canis_lupus_familiaris	ENSCAFP00845032249	71.0345	51.7241
ENSG00000181552	homo_sapiens	ENSP00000314810	77.551	59.8639	panthera_pardus	ENSPPRP00000028086	78.6207	60.6897
ENSG00000181552	homo_sapiens	ENSP00000314810	78.9116	59.1837	marmota_marmota_marmota	ENSMMMP00000016924	76.8212	57.6159
ENSG00000181552	homo_sapiens	ENSP00000314810	72.7891	55.102	balaenoptera_musculus	ENSBMSP00010012166	73.2877	55.4795
ENSG00000181552	homo_sapiens	ENSP00000314810	77.551	59.8639	felis_catus	ENSFCAP00000012770	78.6207	60.6897
ENSG00000181552	homo_sapiens	ENSP00000314810	61.2245	40.8163	monodelphis_domestica	ENSMODP00000034357	48.913	32.6087
ENSG00000181552	homo_sapiens	ENSP00000314810	72.1088	52.381	bison_bison_bison	ENSBBBP00000001783	68.8312	50
ENSG00000181552	homo_sapiens	ENSP00000314810	74.1497	55.102	monodon_monoceros	ENSMMNP00015013305	74.6575	55.4795
ENSG00000181552	homo_sapiens	ENSP00000314810	76.8708	55.102	sus_scrofa	ENSSSCP00000025970	77.3973	55.4795
ENSG00000181552	homo_sapiens	ENSP00000314810	71.4286	50.3401	ovis_aries_rambouillet	ENSOARP00020017056	58.6592	41.3408
ENSG00000181552	homo_sapiens	ENSP00000314810	75.5102	56.4626	ovis_aries_rambouillet	ENSOARP00020017272	76.0274	56.8493
ENSG00000181552	homo_sapiens	ENSP00000314810	68.0272	51.7007	ochotona_princeps	ENSOPRP00000011957	68.9655	52.4138
ENSG00000181552	homo_sapiens	ENSP00000314810	74.1497	55.7823	delphinapterus_leucas	ENSDLEP00000002311	62.2857	46.8571
ENSG00000181552	homo_sapiens	ENSP00000314810	73.4694	53.7415	mus_caroli	MGP_CAROLIEiJ_P0036503	72.4832	53.0201
ENSG00000181552	homo_sapiens	ENSP00000314810	74.8299	54.4218	mus_musculus	ENSMUSP00000098210	73.8255	53.6913
ENSG00000181552	homo_sapiens	ENSP00000314810	78.9116	58.5034	dipodomys_ordii	ENSDORP00000023132	76.3158	56.5789
ENSG00000181552	homo_sapiens	ENSP00000314810	74.1497	55.7823	mustela_putorius_furo	ENSMPUP00000018265	75.1724	56.5517
ENSG00000181552	homo_sapiens	ENSP00000314810	77.551	58.5034	vicugna_pacos	ENSVPAP00000006855	78.0822	58.9041
ENSG00000181552	homo_sapiens	ENSP00000314810	97.9592	96.5986	chlorocebus_sabaeus	ENSCSAP00000017652	97.9592	96.5986
ENSG00000181552	homo_sapiens	ENSP00000314810	77.551	58.5034	camelus_dromedarius	ENSCDRP00005002558	78.0822	58.9041
ENSG00000181552	homo_sapiens	ENSP00000314810	76.8708	58.5034	panthera_tigris_altaica	ENSPTIP00000001586	77.931	59.3103
ENSG00000181552	homo_sapiens	ENSP00000314810	74.1497	55.7823	rattus_norvegicus	ENSRNOP00000040734	76.2238	57.3427
ENSG00000181552	homo_sapiens	ENSP00000314810	74.8299	56.4626	rattus_norvegicus	ENSRNOP00000075575	73.3333	55.3333
ENSG00000181552	homo_sapiens	ENSP00000314810	68.0272	42.1769	peromyscus_maniculatus_bairdii	ENSPEMP00000033096	67.5676	41.8919
ENSG00000181552	homo_sapiens	ENSP00000314810	76.1905	53.0612	peromyscus_maniculatus_bairdii	ENSPEMP00000014635	74.6667	52
ENSG00000181552	homo_sapiens	ENSP00000314810	74.8299	55.7823	mus_spicilegus	ENSMSIP00000023112	73.8255	55.0336
ENSG00000181552	homo_sapiens	ENSP00000314810	74.1497	57.8231	cricetulus_griseus_chok1gshd	ENSCGRP00001014058	72.6667	56.6667
ENSG00000181552	homo_sapiens	ENSP00000314810	73.4694	57.8231	pteropus_vampyrus	ENSPVAP00000012795	73.9726	58.2192
ENSG00000181552	homo_sapiens	ENSP00000314810	75.5102	57.8231	myotis_lucifugus	ENSMLUP00000012895	73.5099	56.2914
ENSG00000181552	homo_sapiens	ENSP00000314810	61.2245	40.1361	vombatus_ursinus	ENSVURP00010026031	61.6438	40.411
ENSG00000181552	homo_sapiens	ENSP00000314810	76.8708	60.5442	rhinolophus_ferrumequinum	ENSRFEP00010025716	77.3973	60.9589
ENSG00000181552	homo_sapiens	ENSP00000314810	73.4694	53.7415	neovison_vison	ENSNVIP00000017006	74.4828	54.4828
ENSG00000181552	homo_sapiens	ENSP00000314810	73.4694	54.4218	neovison_vison	ENSNVIP00000016965	74.4828	55.1724
ENSG00000181552	homo_sapiens	ENSP00000314810	69.3878	51.0204	bos_taurus	ENSBTAP00000068181	72.3404	53.1915
ENSG00000181552	homo_sapiens	ENSP00000314810	70.068	51.0204	canis_lupus_dingo	ENSCAFP00020017993	63.5802	46.2963
ENSG00000181552	homo_sapiens	ENSP00000314810	79.5918	60.5442	sciurus_vulgaris	ENSSVLP00005002057	80.137	60.9589
ENSG00000181552	homo_sapiens	ENSP00000314810	59.1837	40.8163	phascolarctos_cinereus	ENSPCIP00000039169	55.414	38.2166
ENSG00000181552	homo_sapiens	ENSP00000314810	74.8299	55.7823	cervus_hanglu_yarkandensis	ENSCHYP00000021389	75.3425	56.1644
ENSG00000181552	homo_sapiens	ENSP00000314810	75.5102	57.1429	catagonus_wagneri	ENSCWAP00000008427	76.0274	57.5342
ENSG00000181552	homo_sapiens	ENSP00000314810	82.3129	69.3878	otolemur_garnettii	ENSOGAP00000006953	82.3129	69.3878
ENSG00000181552	homo_sapiens	ENSP00000314810	76.1905	57.8231	urocitellus_parryii	ENSUPAP00010002282	74.1722	56.2914
ENSG00000181552	homo_sapiens	ENSP00000314810	76.1905	57.1429	moschus_moschiferus	ENSMMSP00000011160	76.7123	57.5342
ENSG00000181552	homo_sapiens	ENSP00000314810	97.9592	96.5986	rhinopithecus_roxellana	ENSRROP00000027418	97.9592	96.5986
ENSG00000181552	homo_sapiens	ENSP00000314810	73.4694	51.0204	mus_pahari	MGP_PahariEiJ_P0084623	72.4832	50.3356

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0003674	enables molecular_function	1	ND	Homo_sapiens(9606)	Function
GO:0005515	enables protein binding	1	IPI	Homo_sapiens(9606)	Function
GO:0005576	located_in extracellular region	1	IEA	Homo_sapiens(9606)	Component