Functions and Diseases

RBP Type Non-canonical_RBPs
Diseases CancerSARS-COV-2
Drug Drug
Main interacting RNAs N.A.
Moonlighting functions Metabolic enzyme
Localizations N.A.
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000181019 Gene ID 1728 Accession 2874
Symbol NQO1 Alias DTD;QR1;DHQU;DIA4;NMOR1;NMORI Full Name NAD(P)H quinone dehydrogenase 1
Status Confidence Length 19673 bases Strand Minus strand
Position 16 : 69706996 - 69726668 RNA binding domain N.A.
Summary This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal
27515817 Novel RNA-binding activity of NQO1 promotes SERPINA1 mRNA translation. Andrea A Di 2016-10-01 Free radical biology & medicine
33360352 A redox-mediated conformational change in NQO1 controls binding to microtubules and α-tubulin acetylation. David Siegel 2021-02-01 Redox biology
37002649 NQO1 regulates expression and alternative splicing of apoptotic genes associated with Alzheimer's disease in PC12 cells. Yingshi Du 2023-05-01 Brain and behavior
33153185 Naturally-Occurring Rare Mutations Cause Mild to Catastrophic Effects in the Multifunctional and Cancer-Associated NQO1 Protein. Luis Juan Pacheco-García 2020-11-03 Journal of personalized medicine
31470592 Nutritional Stress in Head and Neck Cancer Originating Cell Lines: The Sensitivity of the NRF2-NQO1 Axis. Lidija Milković 2019-08-29 Cells
28883796 Functions of NQO1 in Cellular Protection and CoQ10 Metabolism and its Potential Role as a Redox Sensitive Molecular Switch. David Ross 2017-01-01 Frontiers in physiology
36349191 Serpin family A member 1 is an oncogene in glioma and its translation is enhanced by NAD(P)H quinone dehydrogenase 1 through RNA-binding activity. Wenjun Liu 2022-01-01 Open medicine (Warsaw, Poland)

Transcripts

Name Transcript ID bp Protein Translation ID
NQO1-205 ENST00000561500 891 269aa ENSP00000456282
NQO1-201 ENST00000320623 2521 274aa ENSP00000319788
NQO1-203 ENST00000379047 2527 240aa ENSP00000368335
NQO1-202 ENST00000379046 1105 236aa ENSP00000368334
NQO1-204 ENST00000439109 924 202aa ENSP00000398330
NQO1-206 ENST00000564043 892 253aa ENSP00000455020
NQO1-207 ENST00000569118 519 No protein -

Gene Model

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000181019homo_sapiensENSP0000036982261.471947.1861homo_sapiensENSP0000031978851.824839.781

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000181019homo_sapiensENSP0000031978893.430792.3358nomascus_leucogenysENSNLEP0000004012198.084396.9349
ENSG00000181019homo_sapiensENSP0000031978884.671584.6715pan_paniscusENSPPAP0000002060783.754583.7545
ENSG00000181019homo_sapiensENSP0000031978899.270198.9051pongo_abeliiENSPPYP0000003449899.270198.9051
ENSG00000181019homo_sapiensENSP00000319788100100pan_troglodytesENSPTRP00000014148100100
ENSG00000181019homo_sapiensENSP00000319788100100gorilla_gorillaENSGGOP00000003236100100
ENSG00000181019homo_sapiensENSP0000031978892.700785.0365ornithorhynchus_anatinusENSOANP0000003758692.700785.0365
ENSG00000181019homo_sapiensENSP0000031978889.78179.927sarcophilus_harrisiiENSSHAP0000001793389.78179.927
ENSG00000181019homo_sapiensENSP0000031978874.087666.0584notamacropus_eugeniiENSMEUP0000001457175.185267.037
ENSG00000181019homo_sapiensENSP0000031978893.795687.9562choloepus_hoffmanniENSCHOP0000001187795.185289.2593
ENSG00000181019homo_sapiensENSP0000031978894.890591.2409dasypus_novemcinctusENSDNOP0000003470194.890591.2409
ENSG00000181019homo_sapiensENSP0000031978871.532866.0584erinaceus_europaeusENSEEUP0000000192791.162884.186
ENSG00000181019homo_sapiensENSP0000031978893.065786.4964echinops_telfairiENSETEP0000001231993.406686.8132
ENSG00000181019homo_sapiensENSP0000031978895.985494.8905callithrix_jacchusENSCJAP0000007380793.928692.8571
ENSG00000181019homo_sapiensENSP0000031978898.175296.7153cercocebus_atysENSCATP0000000858398.175296.7153
ENSG00000181019homo_sapiensENSP0000031978897.810296.3504macaca_fascicularisENSMFAP0000000553297.810296.3504
ENSG00000181019homo_sapiensENSP0000031978897.810296.7153macaca_mulattaENSMMUP0000008100697.810296.7153
ENSG00000181019homo_sapiensENSP0000031978897.810296.7153macaca_nemestrinaENSMNEP0000001873197.810296.7153
ENSG00000181019homo_sapiensENSP0000031978897.810296.3504papio_anubisENSPANP0000002951798.168596.7033
ENSG00000181019homo_sapiensENSP0000031978898.175296.7153mandrillus_leucophaeusENSMLEP0000002982598.175296.7153
ENSG00000181019homo_sapiensENSP0000031978866.788363.1387tursiops_truncatusENSTTRP0000000950192.424287.3737
ENSG00000181019homo_sapiensENSP0000031978838.686137.2263vulpes_vulpesENSVVUP0000002357597.247793.578
ENSG00000181019homo_sapiensENSP0000031978891.605886.4964mus_spretusMGP_SPRETEiJ_P008944991.605886.4964
ENSG00000181019homo_sapiensENSP0000031978892.335883.2117equus_asinusENSEASP0000505535292.335883.2117
ENSG00000181019homo_sapiensENSP0000031978893.795690.146capra_hircusENSCHIP0000003132093.795690.146
ENSG00000181019homo_sapiensENSP0000031978893.065789.4161loxodonta_africanaENSLAFP0000000753293.406689.7436
ENSG00000181019homo_sapiensENSP0000031978894.160690.146panthera_leoENSPLOP0000002970394.160690.146
ENSG00000181019homo_sapiensENSP0000031978895.255591.6058ailuropoda_melanoleucaENSAMEP0000000709395.604491.9414
ENSG00000181019homo_sapiensENSP0000031978894.160690.8759bos_indicus_hybridENSBIXP0000502286794.160690.8759
ENSG00000181019homo_sapiensENSP0000031978893.065788.3212oryctolagus_cuniculusENSOCUP0000002685193.065788.3212
ENSG00000181019homo_sapiensENSP0000031978892.335883.2117equus_caballusENSECAP0000007389786.348177.8157
ENSG00000181019homo_sapiensENSP0000031978893.065787.2263canis_lupus_familiarisENSCAFP0084501254093.406687.5458
ENSG00000181019homo_sapiensENSP0000031978894.160690.146panthera_pardusENSPPRP0000002563094.160690.146
ENSG00000181019homo_sapiensENSP0000031978892.335888.3212marmota_marmota_marmotaENSMMMP0000001576792.335888.3212
ENSG00000181019homo_sapiensENSP0000031978867.153362.4088balaenoptera_musculusENSBMSP0001002021086.38580.2817
ENSG00000181019homo_sapiensENSP0000031978890.510984.3066cavia_porcellusENSCPOP0000001118590.181884
ENSG00000181019homo_sapiensENSP0000031978894.525689.781felis_catusENSFCAP0000001819794.525689.781
ENSG00000181019homo_sapiensENSP0000031978890.14686.8613ursus_americanusENSUAMP0000003717494.63691.1877
ENSG00000181019homo_sapiensENSP0000031978888.686181.0219monodelphis_domesticaENSMODP0000000328388.686181.0219
ENSG00000181019homo_sapiensENSP0000031978894.160690.8759bison_bison_bisonENSBBBP0000000872394.160690.8759
ENSG00000181019homo_sapiensENSP0000031978866.423463.1387monodon_monocerosENSMMNP0001500463891.919287.3737
ENSG00000181019homo_sapiensENSP0000031978894.890589.4161sus_scrofaENSSSCP0000006392393.862888.4477
ENSG00000181019homo_sapiensENSP0000031978894.525690.8759microcebus_murinusENSMICP0000001102094.525690.8759
ENSG00000181019homo_sapiensENSP0000031978890.510983.5766octodon_degusENSODEP0000002073190.842583.8828
ENSG00000181019homo_sapiensENSP0000031978888.321281.3869octodon_degusENSODEP0000001991088.970681.9853
ENSG00000181019homo_sapiensENSP0000031978890.510984.6715jaculus_jaculusENSJJAP0000001450291.512985.6089
ENSG00000181019homo_sapiensENSP0000031978894.160690.5109ovis_aries_rambouilletENSOARP0002001280094.160690.5109
ENSG00000181019homo_sapiensENSP0000031978888.321286.1314ursus_maritimusENSUMAP0000002558595.652293.2806
ENSG00000181019homo_sapiensENSP0000031978840.875937.2263ochotona_princepsENSOPRP0000000973766.272260.355
ENSG00000181019homo_sapiensENSP0000031978849.270142.7007delphinapterus_leucasENSDLEP0000000234371.428661.9048
ENSG00000181019homo_sapiensENSP0000031978865.328561.6788physeter_catodonENSPCTP0000502551590.862985.7868
ENSG00000181019homo_sapiensENSP0000031978891.605886.1314mus_caroliMGP_CAROLIEiJ_P008595091.605886.1314
ENSG00000181019homo_sapiensENSP0000031978891.970886.4964mus_musculusENSMUSP0000000394791.970886.4964
ENSG00000181019homo_sapiensENSP0000031978893.065786.1314dipodomys_ordiiENSDORP0000000045792.057885.1986
ENSG00000181019homo_sapiensENSP0000031978894.890591.2409mustela_putorius_furoENSMPUP0000000737465.822863.2911
ENSG00000181019homo_sapiensENSP0000031978870.07369.3431aotus_nancymaaeENSANAP0000002239775.294174.5098
ENSG00000181019homo_sapiensENSP0000031978883.576682.4818saimiri_boliviensis_boliviensisENSSBOP0000002038991.690.4
ENSG00000181019homo_sapiensENSP0000031978895.255592.3358vicugna_pacosENSVPAP0000000188295.255592.3358
ENSG00000181019homo_sapiensENSP0000031978888.321285.4015chlorocebus_sabaeusENSCSAP0000000051194.90291.7647
ENSG00000181019homo_sapiensENSP0000031978891.605887.2263tupaia_belangeriENSTBEP0000001258592.96388.5185
ENSG00000181019homo_sapiensENSP0000031978890.875985.7664mesocricetus_auratusENSMAUP0000000679590.545585.4545
ENSG00000181019homo_sapiensENSP0000031978859.489152.9197phocoena_sinusENSPSNP0000001732063.178356.2015
ENSG00000181019homo_sapiensENSP0000031978894.160691.2409camelus_dromedariusENSCDRP0000502786794.160691.2409
ENSG00000181019homo_sapiensENSP0000031978894.525691.6058carlito_syrichtaENSTSYP0000003188694.525691.6058
ENSG00000181019homo_sapiensENSP0000031978894.160690.146panthera_tigris_altaicaENSPTIP0000001031494.160690.146
ENSG00000181019homo_sapiensENSP0000031978891.240985.4015rattus_norvegicusENSRNOP0000008281491.240985.4015
ENSG00000181019homo_sapiensENSP0000031978895.255590.8759prolemur_simusENSPSMP0000001833983.386679.5527
ENSG00000181019homo_sapiensENSP0000031978887.956278.1022microtus_ochrogasterENSMOCP0000002260887.956278.1022
ENSG00000181019homo_sapiensENSP0000031978887.226378.1022microtus_ochrogasterENSMOCP0000000922687.226378.1022
ENSG00000181019homo_sapiensENSP0000031978880.29276.2774sorex_araneusENSSARP0000001076081.180877.1218
ENSG00000181019homo_sapiensENSP0000031978891.240987.5912peromyscus_maniculatus_bairdiiENSPEMP0000001674491.240987.5912
ENSG00000181019homo_sapiensENSP0000031978894.525691.2409bos_mutusENSBMUP0000000153194.525691.2409
ENSG00000181019homo_sapiensENSP0000031978891.605886.1314mus_spicilegusENSMSIP0000000387791.605886.1314
ENSG00000181019homo_sapiensENSP0000031978890.875986.1314cricetulus_griseus_chok1gshdENSCGRP0000101949490.875986.1314
ENSG00000181019homo_sapiensENSP0000031978891.605883.9416pteropus_vampyrusENSPVAP0000001256892.96385.1852
ENSG00000181019homo_sapiensENSP0000031978894.890589.4161myotis_lucifugusENSMLUP0000001288194.545589.0909
ENSG00000181019homo_sapiensENSP0000031978889.051181.3869vombatus_ursinusENSVURP0001002642889.051181.3869
ENSG00000181019homo_sapiensENSP0000031978893.065788.6861rhinolophus_ferrumequinumENSRFEP0001001053292.727388.3636
ENSG00000181019homo_sapiensENSP0000031978895.255592.3358neovison_visonENSNVIP0000000973695.255592.3358
ENSG00000181019homo_sapiensENSP0000031978893.795690.5109bos_taurusENSBTAP0000007118192.44689.2086
ENSG00000181019homo_sapiensENSP0000031978885.401581.7518heterocephalus_glaber_femaleENSHGLP0000003147692.490188.5376
ENSG00000181019homo_sapiensENSP0000031978861.678858.0292heterocephalus_glaber_femaleENSHGLP0000000826089.893684.5745
ENSG00000181019homo_sapiensENSP0000031978898.905198.5401rhinopithecus_bietiENSRBIP0000002228798.905198.5401
ENSG00000181019homo_sapiensENSP0000031978886.496482.4818canis_lupus_dingoENSCAFP0002002580593.675989.3281
ENSG00000181019homo_sapiensENSP0000031978893.065787.9562sciurus_vulgarisENSSVLP0000503067993.065787.9562
ENSG00000181019homo_sapiensENSP0000031978891.240980.6569phascolarctos_cinereusENSPCIP0000004562761.576454.4335
ENSG00000181019homo_sapiensENSP0000031978874.817568.6131procavia_capensisENSPCAP0000000107874.545568.3636
ENSG00000181019homo_sapiensENSP0000031978891.605884.3066nannospalax_galiliENSNGAP0000001725583.112676.4901
ENSG00000181019homo_sapiensENSP0000031978894.525690.8759bos_grunniensENSBGRP0000000920583.818880.5825
ENSG00000181019homo_sapiensENSP0000031978893.065787.2263chinchilla_lanigeraENSCLAP0000000519493.065787.2263
ENSG00000181019homo_sapiensENSP0000031978894.525691.2409cervus_hanglu_yarkandensisENSCHYP0000003169094.525691.2409
ENSG00000181019homo_sapiensENSP0000031978893.795686.1314catagonus_wagneriENSCWAP0000000469383.986977.1242
ENSG00000181019homo_sapiensENSP0000031978892.700789.0511ictidomys_tridecemlineatusENSSTOP0000001436992.363688.7273
ENSG00000181019homo_sapiensENSP0000031978859.85458.0292otolemur_garnettiiENSOGAP0000000409596.470693.5294
ENSG00000181019homo_sapiensENSP0000031978896.350494.1606cebus_imitatorENSCCAP0000003214880.487878.6585
ENSG00000181019homo_sapiensENSP0000031978893.065789.4161urocitellus_parryiiENSUPAP0001003026693.065789.4161
ENSG00000181019homo_sapiensENSP0000031978894.160690.8759moschus_moschiferusENSMMSP0000000446894.160690.8759
ENSG00000181019homo_sapiensENSP0000031978898.905198.5401rhinopithecus_roxellanaENSRROP0000004197098.905198.5401
ENSG00000181019homo_sapiensENSP0000031978892.700786.8613mus_pahariMGP_PahariEiJ_P005420392.700786.8613
ENSG00000181019homo_sapiensENSP0000031978894.160691.6058propithecus_coquereliENSPCOP0000001876895.555692.963
ENSG00000181019homo_sapiensENSP0000031978869.70855.1095latimeria_chalumnaeENSLACP0000000917075.196959.4488
ENSG00000181019homo_sapiensENSP0000031978868.978150lepisosteus_oculatusENSLOCP0000000328564.948547.079
ENSG00000181019homo_sapiensENSP0000031978871.167949.635danio_rerioENSDARP0000002115070.909149.4545
ENSG00000181019homo_sapiensENSP0000031978868.978149.635carassius_auratusENSCARP0000008160968.478349.2754
ENSG00000181019homo_sapiensENSP0000031978868.613153.2847astyanax_mexicanusENSAMXP0000003678268.115952.8986
ENSG00000181019homo_sapiensENSP0000031978865.328550.7299astyanax_mexicanusENSAMXP0000003204667.547252.4528
ENSG00000181019homo_sapiensENSP0000031978870.43853.6496ictalurus_punctatusENSIPUP0000001683070.69653.8462
ENSG00000181019homo_sapiensENSP0000031978868.248249.635esox_luciusENSELUP0000001645962.126245.1827
ENSG00000181019homo_sapiensENSP0000031978867.883250esox_luciusENSELUP0000006743968.888950.7407
ENSG00000181019homo_sapiensENSP0000031978867.883250esox_luciusENSELUP0000007592968.382450.3676
ENSG00000181019homo_sapiensENSP0000031978868.978150.7299esox_luciusENSELUP000000726167051.4815
ENSG00000181019homo_sapiensENSP0000031978868.613151.0949esox_luciusENSELUP0000007342169.629651.8519
ENSG00000181019homo_sapiensENSP0000031978868.978151.4599esox_luciusENSELUP0000006543469.485351.8382
ENSG00000181019homo_sapiensENSP0000031978868.248249.635esox_luciusENSELUP0000002852068.498249.8168
ENSG00000181019homo_sapiensENSP0000031978868.248250esox_luciusENSELUP0000005236166.312148.5816
ENSG00000181019homo_sapiensENSP0000031978837.956227.3723esox_luciusENSELUP0000006131569.333350
ENSG00000181019homo_sapiensENSP0000031978872.262851.0949oncorhynchus_kisutchENSOKIP0000504764270.462649.8221
ENSG00000181019homo_sapiensENSP0000031978872.262851.0949oncorhynchus_kisutchENSOKIP0000507136370.462649.8221
ENSG00000181019homo_sapiensENSP0000031978871.167951.0949oncorhynchus_mykissENSOMYP0000005787370.397150.5415
ENSG00000181019homo_sapiensENSP0000031978871.167951.0949oncorhynchus_mykissENSOMYP0000005162070.397150.5415
ENSG00000181019homo_sapiensENSP0000031978872.262851.0949salmo_salarENSSSAP0000002159768.041248.11
ENSG00000181019homo_sapiensENSP0000031978867.518251.4599salmo_salarENSSSAP0000005808859.870645.6311
ENSG00000181019homo_sapiensENSP0000031978871.167951.0949salmo_salarENSSSAP0000016598367.47448.4429
ENSG00000181019homo_sapiensENSP0000031978871.897852.1898salmo_truttaENSSTUP0000007753671.897852.1898
ENSG00000181019homo_sapiensENSP0000031978867.883251.0949salmo_truttaENSSTUP0000001807368.382451.4706
ENSG00000181019homo_sapiensENSP0000031978872.262852.1898salmo_truttaENSSTUP0000000233472.262852.1898
ENSG00000181019homo_sapiensENSP0000031978842.700730.6569gadus_morhuaENSGMOP0000000403469.230849.7041
ENSG00000181019homo_sapiensENSP0000031978863.503748.5401fundulus_heteroclitusENSFHEP0000002767363.272748.3636
ENSG00000181019homo_sapiensENSP0000031978858.029241.9708poecilia_reticulataENSPREP0000001376962.352945.098
ENSG00000181019homo_sapiensENSP0000031978868.978153.2847xiphophorus_maculatusENSXMAP0000002129267.552.1429
ENSG00000181019homo_sapiensENSP0000031978855.109542.3358oryzias_latipesENSORLP0000002237365.652250.4348
ENSG00000181019homo_sapiensENSP0000031978832.846722.9927oryzias_latipesENSORLP0000002237666.176546.3235
ENSG00000181019homo_sapiensENSP0000031978866.788349.2701cyclopterus_lumpusENSCLMP0000503157365.357148.2143
ENSG00000181019homo_sapiensENSP0000031978866.058448.5401cyclopterus_lumpusENSCLMP0000503158264.642947.5
ENSG00000181019homo_sapiensENSP0000031978835.036524.4526astatotilapia_callipteraENSACLP0000000228868.571447.8571
ENSG00000181019homo_sapiensENSP0000031978835.036524.4526astatotilapia_callipteraENSACLP0000000230566.206946.2069
ENSG00000181019homo_sapiensENSP0000031978875.547462.7737xenopus_tropicalisENSXETP0000009342372.377660.1399
ENSG00000181019homo_sapiensENSP0000031978880.29266.0584chrysemys_picta_belliiENSCPBP0000003925174.074160.9428
ENSG00000181019homo_sapiensENSP0000031978880.656964.5985sphenodon_punctatusENSSPUP0000000744882.771566.2921
ENSG00000181019homo_sapiensENSP0000031978885.036569.708crocodylus_porosusENSCPRP0000501191370.820758.0547
ENSG00000181019homo_sapiensENSP0000031978867.518254.3796notechis_scutatusENSNSUP0000002866557.453446.2733
ENSG00000181019homo_sapiensENSP0000031978876.642363.1387pseudonaja_textilisENSPTXP0000001198357.692347.5275
ENSG00000181019homo_sapiensENSP0000031978876.642359.854anas_platyrhynchos_platyrhynchosENSAPLP0000001667860.693647.3988
ENSG00000181019homo_sapiensENSP0000031978872.992755.8394gallus_gallusENSGALP0001001135677.82159.5331
ENSG00000181019homo_sapiensENSP0000031978878.467259.854meleagris_gallopavoENSMGAP0000000889655.555642.3773
ENSG00000181019homo_sapiensENSP0000031978879.92764.9635anolis_carolinensisENSACAP0000000358280.219865.2015
ENSG00000181019homo_sapiensENSP0000031978855.839441.6058neolamprologus_brichardiENSNBRP0000001414652.397339.0411
ENSG00000181019homo_sapiensENSP0000031978884.671570.073podarcis_muralisENSPMRP0000001286584.363669.8182
ENSG00000181019homo_sapiensENSP0000031978871.897852.9197erpetoichthys_calabaricusENSECRP0000002847972.161253.1136
ENSG00000181019homo_sapiensENSP0000031978854.379636.4963kryptolebias_marmoratusENSKMAP0000002470961.065640.9836
ENSG00000181019homo_sapiensENSP0000031978882.116865.6934salvator_merianaeENSSMRP0000000913681.521765.2174
ENSG00000181019homo_sapiensENSP0000031978856.569340.8759amphilophus_citrinellusENSACIP0000002530163.265345.7143
ENSG00000181019homo_sapiensENSP0000031978869.70852.5547amphiprion_perculaENSAPEP0000000008069.202952.1739
ENSG00000181019homo_sapiensENSP0000031978873.722656.9343pelodiscus_sinensisENSPSIP0000001363479.527661.4173
ENSG00000181019homo_sapiensENSP0000031978879.197166.0584gopherus_evgoodeiENSGEVP0000501982878.909165.8182
ENSG00000181019homo_sapiensENSP0000031978871.167959.4891chelonoidis_abingdoniiENSCABP0000001087678.947465.9919
ENSG00000181019homo_sapiensENSP0000031978866.058449.2701seriola_dumeriliENSSDUP0000000549366.544149.6324
ENSG00000181019homo_sapiensENSP0000031978866.788350cottoperca_gobioENSCGOP0000004789567.279450.3676
ENSG00000181019homo_sapiensENSP0000031978857.299344.1606anser_brachyrhynchusENSABRP0000000298128.545522
ENSG00000181019homo_sapiensENSP0000031978867.883248.9051gasterosteus_aculeatusENSGACP0000000495568.382449.2647
ENSG00000181019homo_sapiensENSP0000031978856.204440.146gasterosteus_aculeatusENSGACP0000000491870.319650.2283
ENSG00000181019homo_sapiensENSP0000031978867.883248.9051gasterosteus_aculeatusENSGACP0000000493666.906548.2014
ENSG00000181019homo_sapiensENSP0000031978862.773744.8905gasterosteus_aculeatusENSGACP0000000494068.849.2
ENSG00000181019homo_sapiensENSP0000031978845.985435.7664poecilia_formosaENSPFOP0000001563968.478353.2609
ENSG00000181019homo_sapiensENSP0000031978867.518248.1752sander_luciopercaENSSLUP0000000183261.666744
ENSG00000181019homo_sapiensENSP0000031978864.233646.3504sander_luciopercaENSSLUP0000001944267.692348.8462
ENSG00000181019homo_sapiensENSP0000031978870.07353.2847amphiprion_ocellarisENSAOCP0000000819069.565252.8986
ENSG00000181019homo_sapiensENSP0000031978879.56264.5985terrapene_carolina_triunguisENSTMTP0000002763779.272764.3636
ENSG00000181019homo_sapiensENSP0000031978879.56264.5985terrapene_carolina_triunguisENSTMTP0000002615779.272764.3636
ENSG00000181019homo_sapiensENSP0000031978864.233648.9051hucho_huchoENSHHUP0000005573269.565252.9644
ENSG00000181019homo_sapiensENSP0000031978846.715332.8467hucho_huchoENSHHUP0000000533466.666746.875
ENSG00000181019homo_sapiensENSP0000031978836.131427.0073hucho_huchoENSHHUP0000001132070.212852.4823
ENSG00000181019homo_sapiensENSP0000031978871.897850betta_splendensENSBSLP0000002023569.366248.2394
ENSG00000181019homo_sapiensENSP0000031978867.518251.4599pygocentrus_nattereriENSPNAP0000002280766.546850.7194
ENSG00000181019homo_sapiensENSP0000031978866.058449.2701seriola_lalandi_dorsalisENSSLDP0000002652066.544149.6324
ENSG00000181019homo_sapiensENSP0000031978866.058447.4453labrus_bergyltaENSLBEP0000002129165.818247.2727
ENSG00000181019homo_sapiensENSP0000031978862.773747.0803mastacembelus_armatusENSMAMP0000002110267.716550.7874
ENSG00000181019homo_sapiensENSP0000031978833.576623.3577stegastes_partitusENSSPAP0000000963768.656747.7612
ENSG00000181019homo_sapiensENSP0000031978863.138744.8905oncorhynchus_tshawytschaENSOTSP0000504995660.489543.007
ENSG00000181019homo_sapiensENSP0000031978837.226328.4672oncorhynchus_tshawytschaENSOTSP0000507994658.620744.8276
ENSG00000181019homo_sapiensENSP0000031978870.43853.2847nothobranchius_furzeriENSNFUP0001500641867.247450.8711
ENSG00000181019homo_sapiensENSP0000031978854.379640.146nothobranchius_furzeriENSNFUP0001502580653.790639.7112
ENSG00000181019homo_sapiensENSP0000031978866.058448.9051denticeps_clupeoidesENSDCDP0000002718367.790350.1873
ENSG00000181019homo_sapiensENSP0000031978866.423448.9051denticeps_clupeoidesENSDCDP0000002606468.421150.3759
ENSG00000181019homo_sapiensENSP0000031978866.058448.9051denticeps_clupeoidesENSDCDP0000002609967.790350.1873
ENSG00000181019homo_sapiensENSP0000031978865.693448.9051larimichthys_croceaENSLCRP0000502864266.176549.2647
ENSG00000181019homo_sapiensENSP0000031978865.328546.7153larimichthys_croceaENSLCRP0000500596466.296347.4074
ENSG00000181019homo_sapiensENSP0000031978870.07350.7299cyprinus_carpio_carpioENSCCRP0000012950968.085149.2908
ENSG00000181019homo_sapiensENSP0000031978879.197160.9489coturnix_japonicaENSCJPP0000501875063.081448.5465
ENSG00000181019homo_sapiensENSP0000031978868.978153.2847poecilia_latipinnaENSPLAP0000002215667.552.1429
ENSG00000181019homo_sapiensENSP0000031978835.766425.5474sinocyclocheilus_grahamiENSSGRP0000001346758.333341.6667
ENSG00000181019homo_sapiensENSP0000031978861.313945.6204maylandia_zebraENSMZEP0000500359066.932349.8008
ENSG00000181019homo_sapiensENSP0000031978856.934339.781maylandia_zebraENSMZEP0000500345863.934444.6721
ENSG00000181019homo_sapiensENSP0000031978860.948944.8905maylandia_zebraENSMZEP0000500349266.533949.004
ENSG00000181019homo_sapiensENSP0000031978869.343154.3796scleropages_formosusENSSFOP0001503005667.615753.0249
ENSG00000181019homo_sapiensENSP0000031978875.912459.854leptobrachium_leishanenseENSLLEP0000004276066.453752.3962

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0000209involved_in protein polyubiquitination1IEAHomo_sapiens(9606)Process
GO:0002931involved_in response to ischemia1IEAHomo_sapiens(9606)Process
GO:0003723enables RNA binding1HDAHomo_sapiens(9606)Function
GO:0003955enables NAD(P)H dehydrogenase (quinone) activity1IBAHomo_sapiens(9606)Function
GO:0004128enables cytochrome-b5 reductase activity, acting on NAD(P)H1TASHomo_sapiens(9606)Function
GO:0004784enables superoxide dismutase activity1IEAHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005634located_in nucleus1IEAHomo_sapiens(9606)Component
GO:0005737located_in cytoplasm1TASHomo_sapiens(9606)Component
GO:0005829is_active_in cytosol3IBA,IDA,TASHomo_sapiens(9606)Component
GO:0006116involved_in NADH oxidation1IEAHomo_sapiens(9606)Process
GO:0006743involved_in ubiquinone metabolic process1IDAHomo_sapiens(9606)Process
GO:0006805involved_in xenobiotic metabolic process1TASHomo_sapiens(9606)Process
GO:0006809involved_in nitric oxide biosynthetic process1TASHomo_sapiens(9606)Process
GO:0006979involved_in response to oxidative stress1IEPHomo_sapiens(9606)Process
GO:0007271involved_in synaptic transmission, cholinergic1TASHomo_sapiens(9606)Process
GO:0007584involved_in response to nutrient1IEAHomo_sapiens(9606)Process
GO:0008753enables NADPH dehydrogenase (quinone) activity1IEAHomo_sapiens(9606)Function
GO:0009636involved_in response to toxic substance1TASHomo_sapiens(9606)Process
GO:0009725involved_in response to hormone1IEAHomo_sapiens(9606)Process
GO:0009743involved_in response to carbohydrate1IEAHomo_sapiens(9606)Process
GO:0014075involved_in response to amine1IEAHomo_sapiens(9606)Process
GO:0019430involved_in removal of superoxide radicals1IDAHomo_sapiens(9606)Process
GO:0030163involved_in protein catabolic process1IEAHomo_sapiens(9606)Process
GO:0030425located_in dendrite1IEAHomo_sapiens(9606)Component
GO:0032355involved_in response to estradiol1IEAHomo_sapiens(9606)Process
GO:0032496involved_in response to lipopolysaccharide1IEAHomo_sapiens(9606)Process
GO:0033574involved_in response to testosterone1IEAHomo_sapiens(9606)Process
GO:0034599involved_in cellular response to oxidative stress1IDAHomo_sapiens(9606)Process
GO:0042177involved_in negative regulation of protein catabolic process1IDAHomo_sapiens(9606)Process
GO:0042360involved_in vitamin E metabolic process1IDAHomo_sapiens(9606)Process
GO:0042373involved_in vitamin K metabolic process1IDAHomo_sapiens(9606)Process
GO:0042802enables identical protein binding1IPIHomo_sapiens(9606)Function
GO:0043025located_in neuronal cell body1IEAHomo_sapiens(9606)Component
GO:0043066involved_in negative regulation of apoptotic process1IEAHomo_sapiens(9606)Process
GO:0043086involved_in negative regulation of catalytic activity1IEAHomo_sapiens(9606)Process
GO:0043279involved_in response to alkaloid1IEAHomo_sapiens(9606)Process
GO:0043525involved_in positive regulation of neuron apoptotic process1IEAHomo_sapiens(9606)Process
GO:0045087involved_in innate immune response1IEAHomo_sapiens(9606)Process
GO:0045202located_in synapse1IEAHomo_sapiens(9606)Component
GO:0045454involved_in cell redox homeostasis1IEPHomo_sapiens(9606)Process
GO:0045471involved_in response to ethanol1IEAHomo_sapiens(9606)Process
GO:0050136enables NADH dehydrogenase (quinone) activity1IDAHomo_sapiens(9606)Function
GO:0051602involved_in response to electrical stimulus1IEAHomo_sapiens(9606)Process
GO:0070301involved_in cellular response to hydrogen peroxide1IEAHomo_sapiens(9606)Process
GO:0070995involved_in NADPH oxidation1IEAHomo_sapiens(9606)Process
GO:0071248involved_in cellular response to metal ion1IEAHomo_sapiens(9606)Process
GO:1904772involved_in response to tetrachloromethane1IEAHomo_sapiens(9606)Process
GO:1904844involved_in response to L-glutamine1IEAHomo_sapiens(9606)Process
GO:1904880involved_in response to hydrogen sulfide1IEAHomo_sapiens(9606)Process
GO:1905395involved_in response to flavonoid1IEAHomo_sapiens(9606)Process

Expression