RBP Type
Non-canonical_RBPs
Diseases
N.A.
Drug
N.A.
Main interacting RNAs
N.A.
Moonlighting functions
Metabolic enzyme
Localizations
N.A.
BulkPerturb-seq
Ensembl ID ENSG00000180957 Gene ID
23760
Accession
9002
Symbol
PITPNB
Alias
VIB1B;PtdInsTP;PI-TP-beta
Full Name
phosphatidylinositol transfer protein beta
Status
Confidence
Length
68466 bases
Strand
Minus strand
Position
22 : 27851669 - 27920134
RNA binding domain
N.A.
Summary
This gene encodes a cytoplasmic protein that catalyzes the transfer of phosphatidylinositol and phosphatidylcholine between membranes. This transfer activity is required for COPI complex-mediated retrograde transport from the Golgi apparatus to the endoplasmic reticulum. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2013]
RNA binding domains (RBDs)
Protein
Domain
Pfam ID
E-value
Domain number
RNA binding proteomes (RBPomes)
Pubmed ID
Full Name
Cell
Author
Time
Doi
Literatures on RNA binding capacity
Pubmed ID
Title
Author
Time
Journal
Name
Transcript ID
bp
Protein
Translation ID
PITPNB-202
ENST00000335272
2914
271aa
ENSP00000334738
PITPNB-201
ENST00000320996
2826
272aa
ENSP00000321266
PITPNB-210
ENST00000634017
1017
273aa
ENSP00000487693
PITPNB-208
ENST00000477861
786
No protein
-
PITPNB-209
ENST00000493007
564
No protein
-
PITPNB-203
ENST00000415296
884
120aa
ENSP00000406542
PITPNB-204
ENST00000436663
590
167aa
ENSP00000403675
PITPNB-206
ENST00000465179
629
No protein
-
PITPNB-205
ENST00000460566
592
No protein
-
PITPNB-207
ENST00000471825
766
No protein
-
Pathway ID
Pathway Name
Source
ensgID
Trait
pValue
Pubmed ID
ensgID SNP Chromosome Position
Trait PubmedID Or or BEAT
EFO ID
Protein-Protein Interaction (PPI)
Ensembl ID
Source
Target
Species
Protein ID
Perc_pos
Perc_id
Species
Protein ID
Perc_pos
Perc_id
Ensembl ID
Source
Target
Species
Protein ID
Perc_pos
Perc_id
Species
Protein ID
Perc_pos
Perc_id
Go ID
Go term
No. evidence
Entries
Species
Category
GO:0000139 located_in Golgi membrane 2 ISS,TAS Homo_sapiens(9606) Component GO:0005515 enables protein binding 1 IPI Homo_sapiens(9606) Function GO:0005737 is_active_in cytoplasm 1 IBA Homo_sapiens(9606) Component GO:0005789 located_in endoplasmic reticulum membrane 2 ISS,TAS Homo_sapiens(9606) Component GO:0005794 located_in Golgi apparatus 1 ISS Homo_sapiens(9606) Component GO:0006629 involved_in lipid metabolic process 1 NAS Homo_sapiens(9606) Process GO:0006890 involved_in retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum 2 IMP,TAS Homo_sapiens(9606) Process GO:0006997 involved_in nucleus organization 1 TAS Homo_sapiens(9606) Process GO:0008525 enables phosphatidylcholine transporter activity 2 IBA,IDA Homo_sapiens(9606) Function GO:0008526 enables phosphatidylinositol transfer activity 3 IBA,IDA,IMP Homo_sapiens(9606) Function GO:0015914 involved_in phospholipid transport 1 IDA Homo_sapiens(9606) Process GO:0031210 enables phosphatidylcholine binding 2 IBA,IDA Homo_sapiens(9606) Function GO:0035091 enables phosphatidylinositol binding 2 IBA,IDA Homo_sapiens(9606) Function GO:0120009 involved_in intermembrane lipid transfer 1 IEA Homo_sapiens(9606) Process GO:0120019 enables phosphatidylcholine transfer activity 1 IMP Homo_sapiens(9606) Function GO:0140338 enables sphingomyelin transfer activity 1 ISS Homo_sapiens(9606) Function
Copyright © 2023, Bioinformatics Center, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, China. All Rights Reserved.