RBPWorld - a comprehensive database of RNA Binding Proteins

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Functions and Diseases

RBP Type	Non-canonical_RBPs
Diseases	N.A.
Drug	N.A.
Main interacting RNAs	N.A.
Moonlighting functions	Metabolic enzyme
Localizations	N.A.
BulkPerturb-seq

Description

Ensembl ID	ENSG00000179958	Gene ID	79077	Accession	28777
Symbol	DCTPP1	Alias	CDA03;RS21C6;XTP3TPA	Full Name	dCTP pyrophosphatase 1
Status	Confidence	Length	6416 bases	Strand	Minus strand
Position	16 : 30423615 - 30430030	RNA binding domain	N.A.
Summary	The protein encoded by this gene is dCTP pyrophosphatase, which converts dCTP to dCMP and inorganic pyrophosphate. The encoded protein also displays weak activity against dTTP and dATP, but none against dGTP. This protein may be responsible for eliminating excess dCTP after DNA synthesis and may prevent overmethylation of CpG islands. Three transcript variants, one protein-coding and the other two non-protein coding, have been found for this gene. [provided by RefSeq, Dec 2015]

RNA binding domains (RBDs)

Protein	Domain	Pfam ID	E-value	Domain number

RNA binding proteomes (RBPomes)

Pubmed ID	Full Name	Cell	Author	Time	Doi

Literatures on RNA binding capacity

Pubmed ID	Title	Author	Time	Journal
32716908	Silencing DSCAM-AS1 suppresses the growth and invasion of ER-positive breast cancer cells by downregulating both DCTPP1 and QPRT.	Zhang Yue	2020-07-27	Aging

Transcripts

Name	Transcript ID	bp	Protein	Translation ID
DCTPP1-201	ENST00000319285	1181	170aa	ENSP00000322524
DCTPP1-206	ENST00000678016	1024	49aa	ENSP00000503857
DCTPP1-203	ENST00000567983	801	71aa	ENSP00000456612
DCTPP1-204	ENST00000568434	853	49aa	ENSP00000455391
DCTPP1-205	ENST00000568973	878	49aa	ENSP00000460764
DCTPP1-202	ENST00000565758	749	49aa	ENSP00000460933

Gene Model

Click here to download ENSG00000179958's gene model file

Pathways

Pathway ID	Pathway Name	Source

Phenotypes

ensgID	Trait	pValue	Pubmed ID

GWAS

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Protein-Protein Interaction (PPI)

Click here to download ENSG00000179958's PPI file

Paralogs

Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Orthologs

Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Gene Ontology

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0000287	enables magnesium ion binding	1	ISS	Homo_sapiens(9606)	Function
GO:0005515	enables protein binding	1	IPI	Homo_sapiens(9606)	Function
GO:0005634	located_in nucleus	1	IDA	Homo_sapiens(9606)	Component
GO:0005654	located_in nucleoplasm	1	IDA	Homo_sapiens(9606)	Component
GO:0005739	located_in mitochondrion	1	IDA	Homo_sapiens(9606)	Component
GO:0005829	is_active_in cytosol	3	IBA,IDA,ISS	Homo_sapiens(9606)	Component
GO:0006253	involved_in dCTP catabolic process	2	IBA,IMP	Homo_sapiens(9606)	Process
GO:0009143	involved_in nucleoside triphosphate catabolic process	2	IDA,ISS	Homo_sapiens(9606)	Process
GO:0032556	enables pyrimidine deoxyribonucleotide binding	1	IEA	Homo_sapiens(9606)	Function
GO:0042262	involved_in DNA protection	2	IBA,IMP	Homo_sapiens(9606)	Process
GO:0042802	enables identical protein binding	1	IPI	Homo_sapiens(9606)	Function
GO:0046076	NOT involved_in dTTP catabolic process	1	IMP	Homo_sapiens(9606)	Process
GO:0047429	enables nucleoside triphosphate diphosphatase activity	2	IDA,ISS	Homo_sapiens(9606)	Function
GO:0047840	enables dCTP diphosphatase activity	2	IBA,IDA	Homo_sapiens(9606)	Function

Expression