Functions and Diseases

RBP Type Canonical_RBPs
Diseases N.A.
Drug N.A.
Main interacting RNAs N.A.
Moonlighting functions TF
Localizations N.A.
BulkPerturb-seq

Description

Ensembl ID ENSG00000174652 Gene ID 10781 Accession 13059
Symbol ZNF266 Alias HZF1 Full Name zinc finger protein 266
Status Confidence Length 23145 bases Strand Minus strand
Position 19 : 9412429 - 9435573 RNA binding domain zf-met
Summary This gene encodes a protein containing many tandem zinc-finger motifs. Zinc fingers are protein or nucleic acid-binding domains, and may be involved in a variety of functions, including regulation of transcription. This gene is located in a cluster of similar genes encoding zinc finger proteins on chromosome 19. Alternative splicing results in multiple transcript variants for this gene. [provided by RefSeq, Sep 2012]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000466714 zf-met PF12874 0.00013 1
ENSP00000467151 zf-met PF12874 0.0002 1
ENSP00000467315 zf-met PF12874 0.0002 1
ENSP00000467403 zf-met PF12874 0.0002 1
ENSP00000468491 zf-met PF12874 0.0002 1
ENSP00000498589 zf-met PF12874 0.0002 1

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal

Transcripts

Name Transcript ID bp Protein Translation ID
ZNF266-206 ENST00000592904 3544 616aa ENSP00000466714
ZNF266-202 ENST00000588933 3293 549aa ENSP00000467151
ZNF266-201 ENST00000588221 3503 549aa ENSP00000468491
ZNF266-207 ENST00000648978 4401 No protein -
ZNF266-203 ENST00000590306 3317 549aa ENSP00000467315
ZNF266-208 ENST00000651268 3653 549aa ENSP00000498589
ZNF266-205 ENST00000592292 3100 549aa ENSP00000467403
ZNF266-204 ENST00000591213 760 No protein -

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID
34930Platelet Function Tests2.5200000E-006-

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0000122involved_in negative regulation of transcription by RNA polymerase II1IBAHomo_sapiens(9606)Process
GO:0000977enables RNA polymerase II transcription regulatory region sequence-specific DNA binding1IBAHomo_sapiens(9606)Function
GO:0001227enables DNA-binding transcription repressor activity, RNA polymerase II-specific1IBAHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005634located_in nucleus1IEAHomo_sapiens(9606)Component
GO:0046872enables metal ion binding1IEAHomo_sapiens(9606)Function

Expression