RBP Type
Canonical_RBPs
Diseases
Flaviviruses SARS-COV-2 Dengue
Drug
N.A.
Main interacting RNAs
snRNA
Moonlighting functions
N.A.
Localizations
Nucleoli
BulkPerturb-seq
N.A.
Ensembl ID ENSG00000174243 Gene ID
9416
Accession
17347
Symbol
DDX23
Alias
prp28;PRPF28;U5-100K;SNRNP100;U5-100KD
Full Name
DEAD-box helicase 23
Status
Confidence
Length
22421 bases
Strand
Minus strand
Position
12 : 48829756 - 48852176
RNA binding domain
DEAD
Summary
This gene encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene is a component of the U5 snRNP complex; it may facilitate conformational changes in the spliceosome during nuclear pre-mRNA splicing. An alternatively spliced transcript variant has been found for this gene, but its biological validity has not been determined. [provided by RefSeq, Jul 2008]
RNA binding domains (RBDs)
Protein
Domain
Pfam ID
E-value
Domain number
ENSP00000515223
DEAD
PF00270
4.8e-53
1
ENSP00000310723
DEAD
PF00270
5.4e-53
1
ENSP00000515226
DEAD
PF00270
5.8e-49
1
ENSP00000515225
DEAD
PF00270
1.1e-48
1
ENSP00000448542
DEAD
PF00270
1.5e-11
1
RNA binding proteomes (RBPomes)
Pubmed ID
Full Name
Cell
Author
Time
Doi
Literatures on RNA binding capacity
Pubmed ID
Title
Author
Time
Journal
33255534
The DDX23 Negatively Regulates Translation and Replication of Foot-and-Mouth Disease Virus and Is Degraded by 3C Proteinase.
Waheed Sahibzada Abdullah
2020-11-25
Viruses
31620127
DDX23, an Evolutionary Conserved dsRNA Sensor, Participates in Innate Antiviral Responses by Pairing With TRIF or MAVS.
Jie Ruan
2019-01-01
Frontiers in immunology
27048167
The new (dis)order in RNA regulation.
I Aino Järvelin
2016-04-06
Cell communication and signaling : CCS
32033386
DEAD-Box Helicases: Sensors, Regulators, and Effectors for Antiviral Defense.
Frances Taschuk
2020-02-05
Viruses
Name
Transcript ID
bp
Protein
Translation ID
DDX23-201
ENST00000308025
3256
820aa
ENSP00000310723
DDX23-219
ENST00000703178
1779
No protein
-
DDX23-220
ENST00000703179
3130
783aa
ENSP00000515223
DDX23-213
ENST00000552369
3372
184aa
ENSP00000515224
DDX23-221
ENST00000703180
3109
No protein
-
DDX23-222
ENST00000703181
3648
619aa
ENSP00000515225
DDX23-223
ENST00000703182
2662
435aa
ENSP00000515226
DDX23-208
ENST00000551098
3452
No protein
-
DDX23-204
ENST00000547290
2834
No protein
-
DDX23-206
ENST00000549795
3721
No protein
-
DDX23-207
ENST00000550834
869
259aa
ENSP00000449657
DDX23-210
ENST00000551331
706
No protein
-
DDX23-205
ENST00000547842
554
No protein
-
DDX23-216
ENST00000552802
926
152aa
ENSP00000448542
DDX23-217
ENST00000553065
336
No protein
-
DDX23-202
ENST00000547135
1377
108aa
ENSP00000446770
DDX23-203
ENST00000547165
958
No protein
-
DDX23-212
ENST00000552069
592
No protein
-
DDX23-209
ENST00000551189
587
No protein
-
DDX23-218
ENST00000553182
779
No protein
-
DDX23-214
ENST00000552512
696
182aa
ENSP00000449639
DDX23-211
ENST00000551468
567
138aa
ENSP00000446948
DDX23-215
ENST00000552555
562
No protein
-
Pathway ID
Pathway Name
Source
ensgID
Trait
pValue
Pubmed ID
ensgID SNP Chromosome Position
Trait PubmedID Or or BEAT
EFO ID
Protein-Protein Interaction (PPI)
Ensembl ID
Source
Target
Species
Protein ID
Perc_pos
Perc_id
Species
Protein ID
Perc_pos
Perc_id
ENSG00000174243 homo_sapiens ENSP00000379475 48.5981 28.0374 homo_sapiens ENSP00000310723 25.3659 14.6341 ENSG00000174243 homo_sapiens ENSP00000385536 35.6653 23.1824 homo_sapiens ENSP00000310723 31.7073 20.6098 ENSG00000174243 homo_sapiens ENSP00000263239 34.1791 19.2537 homo_sapiens ENSP00000310723 27.9268 15.7317 ENSG00000174243 homo_sapiens ENSP00000497641 46.2287 27.2506 homo_sapiens ENSP00000310723 23.1707 13.6585 ENSG00000174243 homo_sapiens ENSP00000482680 42.3529 25.7516 homo_sapiens ENSP00000310723 39.5122 24.0244 ENSG00000174243 homo_sapiens ENSP00000293831 49.2611 29.5567 homo_sapiens ENSP00000310723 24.3902 14.6341 ENSG00000174243 homo_sapiens ENSP00000306117 41.841 23.6402 homo_sapiens ENSP00000310723 24.3902 13.7805 ENSG00000174243 homo_sapiens ENSP00000288071 41.7537 23.382 homo_sapiens ENSP00000310723 24.3902 13.6585 ENSG00000174243 homo_sapiens ENSP00000481495 28.0559 15.4831 homo_sapiens ENSP00000310723 29.3902 16.2195 ENSG00000174243 homo_sapiens ENSP00000416534 28.7791 18.314 homo_sapiens ENSP00000310723 36.2195 23.0488 ENSG00000174243 homo_sapiens ENSP00000361232 29.6247 17.8284 homo_sapiens ENSP00000310723 26.9512 16.2195 ENSG00000174243 homo_sapiens ENSP00000492643 14.7368 7.89474 homo_sapiens ENSP00000310723 23.9024 12.8049 ENSG00000174243 homo_sapiens ENSP00000238146 33 20.8333 homo_sapiens ENSP00000310723 24.1463 15.2439 ENSG00000174243 homo_sapiens ENSP00000225792 42.5081 27.3616 homo_sapiens ENSP00000310723 31.8293 20.4878 ENSG00000174243 homo_sapiens ENSP00000368667 41.5214 24.5642 homo_sapiens ENSP00000310723 31.9512 18.9024 ENSG00000174243 homo_sapiens ENSP00000330460 42.9725 25.8481 homo_sapiens ENSP00000310723 32.439 19.5122 ENSG00000174243 homo_sapiens ENSP00000263576 38.7164 22.3602 homo_sapiens ENSP00000310723 22.8049 13.1707 ENSG00000174243 homo_sapiens ENSP00000380495 33.3333 19.3694 homo_sapiens ENSP00000310723 27.0732 15.7317 ENSG00000174243 homo_sapiens ENSP00000314348 22.8571 14.0571 homo_sapiens ENSP00000310723 24.3902 15 ENSG00000174243 homo_sapiens ENSP00000346120 32.9502 18.9017 homo_sapiens ENSP00000310723 31.4634 18.0488 ENSG00000174243 homo_sapiens ENSP00000374574 28.145 18.2303 homo_sapiens ENSP00000310723 32.1951 20.8537 ENSG00000174243 homo_sapiens ENSP00000358716 23.0583 13.9563 homo_sapiens ENSP00000310723 23.1707 14.0244 ENSG00000174243 homo_sapiens ENSP00000442266 44.0994 25.4658 homo_sapiens ENSP00000310723 25.9756 15 ENSG00000174243 homo_sapiens ENSP00000362687 31.886 19.1316 homo_sapiens ENSP00000310723 28.6585 17.1951 ENSG00000174243 homo_sapiens ENSP00000479504 41.0684 23.5392 homo_sapiens ENSP00000310723 30 17.1951 ENSG00000174243 homo_sapiens ENSP00000359361 43.0556 27.7778 homo_sapiens ENSP00000310723 34.0244 21.9512 ENSG00000174243 homo_sapiens ENSP00000326381 49.3857 30.2211 homo_sapiens ENSP00000310723 24.5122 15 ENSG00000174243 homo_sapiens ENSP00000258772 31.2614 19.0128 homo_sapiens ENSP00000310723 20.8537 12.6829 ENSG00000174243 homo_sapiens ENSP00000494040 40.4834 28.5498 homo_sapiens ENSP00000310723 32.6829 23.0488 ENSG00000174243 homo_sapiens ENSP00000336725 39.5455 27.8788 homo_sapiens ENSP00000310723 31.8293 22.439 ENSG00000174243 homo_sapiens ENSP00000247003 39.1304 25.8799 homo_sapiens ENSP00000310723 23.0488 15.2439 ENSG00000174243 homo_sapiens ENSP00000330349 42.7653 27.1704 homo_sapiens ENSP00000310723 32.439 20.6098 ENSG00000174243 homo_sapiens ENSP00000242776 48.0094 28.8056 homo_sapiens ENSP00000310723 25 15 ENSG00000174243 homo_sapiens ENSP00000233084 28.7838 17.1622 homo_sapiens ENSP00000310723 25.9756 15.4878 ENSG00000174243 homo_sapiens ENSP00000304072 25.3121 15.7775 homo_sapiens ENSP00000310723 27.1951 16.9512 ENSG00000174243 homo_sapiens ENSP00000350698 45.9341 32.5275 homo_sapiens ENSP00000310723 25.4878 18.0488 ENSG00000174243 homo_sapiens ENSP00000332340 37.2222 22.963 homo_sapiens ENSP00000310723 24.5122 15.122 ENSG00000174243 homo_sapiens ENSP00000424838 34.3923 22.6519 homo_sapiens ENSP00000310723 30.3659 20
Ensembl ID
Source
Target
Species
Protein ID
Perc_pos
Perc_id
Species
Protein ID
Perc_pos
Perc_id
ENSG00000174243 homo_sapiens ENSP00000310723 93.0488 92.9268 nomascus_leucogenys ENSNLEP00000021705 98.5788 98.4496 ENSG00000174243 homo_sapiens ENSP00000310723 100 100 pan_paniscus ENSPPAP00000029696 100 100 ENSG00000174243 homo_sapiens ENSP00000310723 100 100 pongo_abelii ENSPPYP00000005101 100 100 ENSG00000174243 homo_sapiens ENSP00000310723 100 99.8781 pan_troglodytes ENSPTRP00000087267 100 99.8781 ENSG00000174243 homo_sapiens ENSP00000310723 100 100 gorilla_gorilla ENSGGOP00000014885 100 100 ENSG00000174243 homo_sapiens ENSP00000310723 90.8537 89.1463 ornithorhynchus_anatinus ENSOANP00000033680 94.9045 93.121 ENSG00000174243 homo_sapiens ENSP00000310723 99.0244 97.561 sarcophilus_harrisii ENSSHAP00000007581 99.2665 97.7995 ENSG00000174243 homo_sapiens ENSP00000310723 99.0244 97.561 notamacropus_eugenii ENSMEUP00000008654 99.2665 97.7995 ENSG00000174243 homo_sapiens ENSP00000310723 83.7805 83.2927 choloepus_hoffmanni ENSCHOP00000007988 99.8547 99.2733 ENSG00000174243 homo_sapiens ENSP00000310723 99.8781 99.5122 dasypus_novemcinctus ENSDNOP00000034267 99.8781 99.5122 ENSG00000174243 homo_sapiens ENSP00000310723 92.561 91.2195 erinaceus_europaeus ENSEEUP00000008818 92.3358 90.9976 ENSG00000174243 homo_sapiens ENSP00000310723 95.9756 94.7561 echinops_telfairi ENSETEP00000012830 97.401 96.1634 ENSG00000174243 homo_sapiens ENSP00000310723 99.8781 99.7561 callithrix_jacchus ENSCJAP00000038667 99.8781 99.7561 ENSG00000174243 homo_sapiens ENSP00000310723 99.8781 99.8781 cercocebus_atys ENSCATP00000033657 99.8781 99.8781 ENSG00000174243 homo_sapiens ENSP00000310723 99.8781 99.8781 macaca_fascicularis ENSMFAP00000038753 91.9192 91.9192 ENSG00000174243 homo_sapiens ENSP00000310723 99.8781 99.8781 macaca_mulatta ENSMMUP00000053303 99.8781 99.8781 ENSG00000174243 homo_sapiens ENSP00000310723 99.7561 99.6341 macaca_nemestrina ENSMNEP00000033645 99.7561 99.6341 ENSG00000174243 homo_sapiens ENSP00000310723 99.8781 99.8781 papio_anubis ENSPANP00000002455 99.8781 99.8781 ENSG00000174243 homo_sapiens ENSP00000310723 99.8781 99.8781 mandrillus_leucophaeus ENSMLEP00000037545 99.8781 99.8781 ENSG00000174243 homo_sapiens ENSP00000310723 93.6585 93.2927 tursiops_truncatus ENSTTRP00000004351 93.8875 93.5208 ENSG00000174243 homo_sapiens ENSP00000310723 99.8781 99.6341 vulpes_vulpes ENSVVUP00000026752 99.8781 99.6341 ENSG00000174243 homo_sapiens ENSP00000310723 99.5122 98.5366 mus_spretus MGP_SPRETEiJ_P0041532 99.6337 98.6569 ENSG00000174243 homo_sapiens ENSP00000310723 99.7561 99.5122 equus_asinus ENSEASP00005000472 99.7561 99.5122 ENSG00000174243 homo_sapiens ENSP00000310723 99.7561 99.2683 capra_hircus ENSCHIP00000019975 99.7561 99.2683 ENSG00000174243 homo_sapiens ENSP00000310723 99.7561 99.2683 loxodonta_africana ENSLAFP00000011913 99.7561 99.2683 ENSG00000174243 homo_sapiens ENSP00000310723 99.8781 99.7561 panthera_leo ENSPLOP00000013753 99.8781 99.7561 ENSG00000174243 homo_sapiens ENSP00000310723 99.8781 99.6341 ailuropoda_melanoleuca ENSAMEP00000007536 99.8781 99.6341 ENSG00000174243 homo_sapiens ENSP00000310723 99.7561 99.3902 bos_indicus_hybrid ENSBIXP00005016924 89.989 89.659 ENSG00000174243 homo_sapiens ENSP00000310723 99.6341 98.9024 oryctolagus_cuniculus ENSOCUP00000026866 99.0303 98.303 ENSG00000174243 homo_sapiens ENSP00000310723 99.7561 99.6341 equus_caballus ENSECAP00000014386 95.7845 95.6674 ENSG00000174243 homo_sapiens ENSP00000310723 99.8781 99.6341 canis_lupus_familiaris ENSCAFP00845032615 99.3932 99.1505 ENSG00000174243 homo_sapiens ENSP00000310723 99.8781 99.7561 panthera_pardus ENSPPRP00000025116 99.8781 99.7561 ENSG00000174243 homo_sapiens ENSP00000310723 99.8781 99.6341 marmota_marmota_marmota ENSMMMP00000026217 99.8781 99.6341 ENSG00000174243 homo_sapiens ENSP00000310723 99.6341 99.1463 balaenoptera_musculus ENSBMSP00010023067 99.8778 99.3888 ENSG00000174243 homo_sapiens ENSP00000310723 99.6341 99.1463 cavia_porcellus ENSCPOP00000002963 99.7558 99.2674 ENSG00000174243 homo_sapiens ENSP00000310723 99.8781 99.7561 felis_catus ENSFCAP00000031300 99.8781 99.7561 ENSG00000174243 homo_sapiens ENSP00000310723 99.8781 99.7561 ursus_americanus ENSUAMP00000035661 99.8781 99.7561 ENSG00000174243 homo_sapiens ENSP00000310723 99.2683 97.8049 monodelphis_domestica ENSMODP00000012490 99.511 98.044 ENSG00000174243 homo_sapiens ENSP00000310723 99.7561 99.3902 bison_bison_bison ENSBBBP00000027633 99.7561 99.3902 ENSG00000174243 homo_sapiens ENSP00000310723 99.6341 99.2683 monodon_monoceros ENSMMNP00015029306 99.8778 99.511 ENSG00000174243 homo_sapiens ENSP00000310723 99.7561 99.5122 sus_scrofa ENSSSCP00000000183 99.7561 99.5122 ENSG00000174243 homo_sapiens ENSP00000310723 99.5122 99.3902 microcebus_murinus ENSMICP00000020726 99.7555 99.6333 ENSG00000174243 homo_sapiens ENSP00000310723 99.7561 99.3902 octodon_degus ENSODEP00000004723 99.8779 99.5116 ENSG00000174243 homo_sapiens ENSP00000310723 99.6341 99.3902 jaculus_jaculus ENSJJAP00000017440 99.6341 99.3902 ENSG00000174243 homo_sapiens ENSP00000310723 99.7561 99.2683 ovis_aries_rambouillet ENSOARP00020001921 99.7561 99.2683 ENSG00000174243 homo_sapiens ENSP00000310723 99.8781 99.7561 ursus_maritimus ENSUMAP00000008566 99.8781 99.7561 ENSG00000174243 homo_sapiens ENSP00000310723 99.3902 99.0244 ochotona_princeps ENSOPRP00000006568 99.6333 99.2665 ENSG00000174243 homo_sapiens ENSP00000310723 99.6341 99.2683 delphinapterus_leucas ENSDLEP00000007762 99.8778 99.511 ENSG00000174243 homo_sapiens ENSP00000310723 99.6341 99.2683 physeter_catodon ENSPCTP00005012874 99.8778 99.511 ENSG00000174243 homo_sapiens ENSP00000310723 99.5122 98.4146 mus_caroli MGP_CAROLIEiJ_P0039697 99.6337 98.5348 ENSG00000174243 homo_sapiens ENSP00000310723 99.5122 98.5366 mus_musculus ENSMUSP00000003450 99.6337 98.6569 ENSG00000174243 homo_sapiens ENSP00000310723 99.8781 99.7561 dipodomys_ordii ENSDORP00000011903 99.8781 99.7561 ENSG00000174243 homo_sapiens ENSP00000310723 99.8781 99.7561 mustela_putorius_furo ENSMPUP00000014630 99.8781 99.7561 ENSG00000174243 homo_sapiens ENSP00000310723 99.8781 99.7561 aotus_nancymaae ENSANAP00000002725 99.8781 99.7561 ENSG00000174243 homo_sapiens ENSP00000310723 99.7561 99.5122 saimiri_boliviensis_boliviensis ENSSBOP00000018449 99.7561 99.5122 ENSG00000174243 homo_sapiens ENSP00000310723 99.8781 99.8781 chlorocebus_sabaeus ENSCSAP00000002536 99.8781 99.8781 ENSG00000174243 homo_sapiens ENSP00000310723 95.2439 95.2439 tupaia_belangeri ENSTBEP00000014706 95.2439 95.2439 ENSG00000174243 homo_sapiens ENSP00000310723 99.2683 98.7805 mesocricetus_auratus ENSMAUP00000011867 99.511 99.022 ENSG00000174243 homo_sapiens ENSP00000310723 86.9512 85.2439 phocoena_sinus ENSPSNP00000016835 90.828 89.0446 ENSG00000174243 homo_sapiens ENSP00000310723 99.8781 99.7561 camelus_dromedarius ENSCDRP00005011395 99.8781 99.7561 ENSG00000174243 homo_sapiens ENSP00000310723 99.7561 99.3902 carlito_syrichta ENSTSYP00000004970 99.7561 99.3902 ENSG00000174243 homo_sapiens ENSP00000310723 99.8781 99.7561 panthera_tigris_altaica ENSPTIP00000021857 99.8781 99.7561 ENSG00000174243 homo_sapiens ENSP00000310723 99.5122 98.5366 rattus_norvegicus ENSRNOP00000072026 99.5122 98.5366 ENSG00000174243 homo_sapiens ENSP00000310723 99.8781 99.7561 prolemur_simus ENSPSMP00000007576 99.8781 99.7561 ENSG00000174243 homo_sapiens ENSP00000310723 99.2683 98.4146 microtus_ochrogaster ENSMOCP00000021724 99.3895 98.5348 ENSG00000174243 homo_sapiens ENSP00000310723 91.8293 91.5854 sorex_araneus ENSSARP00000004132 92.1665 91.9217 ENSG00000174243 homo_sapiens ENSP00000310723 99.5122 99.0244 peromyscus_maniculatus_bairdii ENSPEMP00000010267 99.6337 99.1453 ENSG00000174243 homo_sapiens ENSP00000310723 99.7561 99.3902 bos_mutus ENSBMUP00000030755 99.7561 99.3902 ENSG00000174243 homo_sapiens ENSP00000310723 99.5122 98.2927 mus_spicilegus ENSMSIP00000001235 99.6337 98.4127 ENSG00000174243 homo_sapiens ENSP00000310723 99.5122 99.1463 cricetulus_griseus_chok1gshd ENSCGRP00001014113 99.6337 99.2674 ENSG00000174243 homo_sapiens ENSP00000310723 99.8781 99.8781 pteropus_vampyrus ENSPVAP00000009255 99.8781 99.8781 ENSG00000174243 homo_sapiens ENSP00000310723 99.5122 98.9024 myotis_lucifugus ENSMLUP00000010064 99.7555 99.1443 ENSG00000174243 homo_sapiens ENSP00000310723 97.0732 94.6341 myotis_lucifugus ENSMLUP00000019823 97.1917 94.7497 ENSG00000174243 homo_sapiens ENSP00000310723 99.1463 97.8049 vombatus_ursinus ENSVURP00010008187 99.3888 98.044 ENSG00000174243 homo_sapiens ENSP00000310723 99.8781 99.7561 rhinolophus_ferrumequinum ENSRFEP00010013571 99.8781 99.7561 ENSG00000174243 homo_sapiens ENSP00000310723 91.4634 91.4634 neovison_vison ENSNVIP00000009217 100 100 ENSG00000174243 homo_sapiens ENSP00000310723 99.7561 99.3902 bos_taurus ENSBTAP00000029071 99.7561 99.3902 ENSG00000174243 homo_sapiens ENSP00000310723 99.6341 99.2683 heterocephalus_glaber_female ENSHGLP00000005877 97.2619 96.9048 ENSG00000174243 homo_sapiens ENSP00000310723 88.1707 87.561 rhinopithecus_bieti ENSRBIP00000033182 97.047 96.3758 ENSG00000174243 homo_sapiens ENSP00000310723 99.8781 99.6341 canis_lupus_dingo ENSCAFP00020016687 99.8781 99.6341 ENSG00000174243 homo_sapiens ENSP00000310723 99.8781 99.6341 sciurus_vulgaris ENSSVLP00005015546 99.8781 99.6341 ENSG00000174243 homo_sapiens ENSP00000310723 98.9024 97.439 phascolarctos_cinereus ENSPCIP00000043622 99.1443 97.6773 ENSG00000174243 homo_sapiens ENSP00000310723 95.2439 94.6341 procavia_capensis ENSPCAP00000001921 95.2439 94.6341 ENSG00000174243 homo_sapiens ENSP00000310723 99.5122 99.2683 nannospalax_galili ENSNGAP00000019091 99.5122 99.2683 ENSG00000174243 homo_sapiens ENSP00000310723 98.6585 97.9268 bos_grunniens ENSBGRP00000001457 85.6085 84.9735 ENSG00000174243 homo_sapiens ENSP00000310723 99.6341 99.1463 chinchilla_lanigera ENSCLAP00000004185 99.7558 99.2674 ENSG00000174243 homo_sapiens ENSP00000310723 97.8049 96.3415 cervus_hanglu_yarkandensis ENSCHYP00000014417 95.1364 93.7129 ENSG00000174243 homo_sapiens ENSP00000310723 99.7561 99.3902 cervus_hanglu_yarkandensis ENSCHYP00000009862 99.7561 99.3902 ENSG00000174243 homo_sapiens ENSP00000310723 99.8781 99.6341 catagonus_wagneri ENSCWAP00000026356 99.8781 99.6341 ENSG00000174243 homo_sapiens ENSP00000310723 99.8781 99.5122 ictidomys_tridecemlineatus ENSSTOP00000003802 99.8781 99.5122 ENSG00000174243 homo_sapiens ENSP00000310723 99.8781 99.6341 otolemur_garnettii ENSOGAP00000015057 99.8781 99.6341 ENSG00000174243 homo_sapiens ENSP00000310723 84.8781 84.5122 cebus_imitator ENSCCAP00000022762 99.0043 98.5775 ENSG00000174243 homo_sapiens ENSP00000310723 99.8781 99.6341 urocitellus_parryii ENSUPAP00010011287 99.8781 99.6341 ENSG00000174243 homo_sapiens ENSP00000310723 99.6341 98.9024 moschus_moschiferus ENSMMSP00000014861 99.6341 98.9024 ENSG00000174243 homo_sapiens ENSP00000310723 100 100 rhinopithecus_roxellana ENSRROP00000009099 100 100 ENSG00000174243 homo_sapiens ENSP00000310723 99.5122 98.4146 mus_pahari MGP_PahariEiJ_P0043048 99.6337 98.5348 ENSG00000174243 homo_sapiens ENSP00000310723 99.8781 99.7561 propithecus_coquereli ENSPCOP00000026999 99.8781 99.7561 ENSG00000174243 homo_sapiens ENSP00000310723 67.1951 54.1463 caenorhabditis_elegans F01F1.7.1 75.4795 60.8219 ENSG00000174243 homo_sapiens ENSP00000310723 79.3902 65.9756 drosophila_melanogaster FBpp0080622 79.1971 65.8151 ENSG00000174243 homo_sapiens ENSP00000310723 79.3902 66.3415 ciona_intestinalis ENSCINP00000003866 83.5687 69.8331 ENSG00000174243 homo_sapiens ENSP00000310723 84.1463 74.3902 petromyzon_marinus ENSPMAP00000009515 92.1228 81.4419 ENSG00000174243 homo_sapiens ENSP00000310723 77.0732 69.8781 eptatretus_burgeri ENSEBUP00000004863 92.5329 83.8946 ENSG00000174243 homo_sapiens ENSP00000310723 34.3902 33.1707 callorhinchus_milii ENSCMIP00000008262 98.9474 95.4386 ENSG00000174243 homo_sapiens ENSP00000310723 89.1463 84.3902 latimeria_chalumnae ENSLACP00000019302 97.3369 92.1438 ENSG00000174243 homo_sapiens ENSP00000310723 94.3902 86.8293 lepisosteus_oculatus ENSLOCP00000008960 94.621 87.0416 ENSG00000174243 homo_sapiens ENSP00000310723 87.3171 80 clupea_harengus ENSCHAP00000006659 87.9607 80.5897 ENSG00000174243 homo_sapiens ENSP00000310723 93.0488 85 danio_rerio ENSDARP00000007528 94.5477 86.3693 ENSG00000174243 homo_sapiens ENSP00000310723 93.7805 85.3659 carassius_auratus ENSCARP00000015903 94.5879 86.1009 ENSG00000174243 homo_sapiens ENSP00000310723 92.8049 83.9024 carassius_auratus ENSCARP00000103271 94.1832 85.1485 ENSG00000174243 homo_sapiens ENSP00000310723 93.1707 85.6098 astyanax_mexicanus ENSAMXP00000018127 93.9729 86.3469 ENSG00000174243 homo_sapiens ENSP00000310723 93.2927 85.6098 ictalurus_punctatus ENSIPUP00000007636 94.6782 86.8812 ENSG00000174243 homo_sapiens ENSP00000310723 85.9756 76.9512 esox_lucius ENSELUP00000015371 76.7974 68.7364 ENSG00000174243 homo_sapiens ENSP00000310723 80.9756 76.4634 electrophorus_electricus ENSEEEP00000052258 96.2319 90.8696 ENSG00000174243 homo_sapiens ENSP00000310723 41.4634 38.1707 oncorhynchus_kisutch ENSOKIP00005022694 76.0626 70.0224 ENSG00000174243 homo_sapiens ENSP00000310723 89.2683 81.0976 oncorhynchus_kisutch ENSOKIP00005035308 88.835 80.7039 ENSG00000174243 homo_sapiens ENSP00000310723 90.4878 81.3415 oncorhynchus_mykiss ENSOMYP00000079104 91.0429 81.8405 ENSG00000174243 homo_sapiens ENSP00000310723 57.6829 47.439 oncorhynchus_mykiss ENSOMYP00000127494 76.045 62.5402 ENSG00000174243 homo_sapiens ENSP00000310723 90.4878 81.3415 salmo_salar ENSSSAP00000076030 85.4839 76.8433 ENSG00000174243 homo_sapiens ENSP00000310723 31.5854 29.6341 salmo_salar ENSSSAP00000077560 88.0952 82.6531 ENSG00000174243 homo_sapiens ENSP00000310723 32.6829 30.8537 salmo_trutta ENSSTUP00000110700 92.0962 86.9416 ENSG00000174243 homo_sapiens ENSP00000310723 90.4878 81.3415 salmo_trutta ENSSTUP00000073008 91.0429 81.8405 ENSG00000174243 homo_sapiens ENSP00000310723 90.1219 81.7073 gadus_morhua ENSGMOP00000010255 92.8392 84.1709 ENSG00000174243 homo_sapiens ENSP00000310723 92.561 84.3902 fundulus_heteroclitus ENSFHEP00000031511 94.403 86.0696 ENSG00000174243 homo_sapiens ENSP00000310723 92.439 85 poecilia_reticulata ENSPREP00000010375 94.1615 86.5839 ENSG00000174243 homo_sapiens ENSP00000310723 92.1951 85.1219 xiphophorus_maculatus ENSXMAP00000017438 93.913 86.7081 ENSG00000174243 homo_sapiens ENSP00000310723 91.5854 83.7805 oryzias_latipes ENSORLP00000034590 93.6409 85.6609 ENSG00000174243 homo_sapiens ENSP00000310723 86.9512 79.3902 cyclopterus_lumpus ENSCLMP00005026169 87.4847 79.8773 ENSG00000174243 homo_sapiens ENSP00000310723 92.0732 85.6098 oreochromis_niloticus ENSONIP00000039690 90.5276 84.1727 ENSG00000174243 homo_sapiens ENSP00000310723 91.9512 85.6098 haplochromis_burtoni ENSHBUP00000010342 93.5484 87.0968 ENSG00000174243 homo_sapiens ENSP00000310723 91.9512 84.8781 sparus_aurata ENSSAUP00010029469 93.5484 86.3524 ENSG00000174243 homo_sapiens ENSP00000310723 92.1951 85.3659 lates_calcarifer ENSLCAP00010042006 93.7965 86.8486 ENSG00000174243 homo_sapiens ENSP00000310723 94.5122 90.8537 xenopus_tropicalis ENSXETP00000093918 96.1538 92.4318 ENSG00000174243 homo_sapiens ENSP00000310723 97.439 95.2439 chrysemys_picta_bellii ENSCPBP00000028275 98.278 96.064 ENSG00000174243 homo_sapiens ENSP00000310723 98.0488 95.8537 sphenodon_punctatus ENSSPUP00000020893 98.2885 96.088 ENSG00000174243 homo_sapiens ENSP00000310723 92.0732 89.5122 crocodylus_porosus ENSCPRP00005002112 95.4488 92.7939 ENSG00000174243 homo_sapiens ENSP00000310723 98.1707 95.2439 laticauda_laticaudata ENSLLTP00000008385 98.0512 95.1279 ENSG00000174243 homo_sapiens ENSP00000310723 87.439 84.6341 notechis_scutatus ENSNSUP00000004694 98.489 95.3297 ENSG00000174243 homo_sapiens ENSP00000310723 98.1707 95.2439 pseudonaja_textilis ENSPTXP00000009636 98.0512 95.1279 ENSG00000174243 homo_sapiens ENSP00000310723 85.3659 82.8049 anas_platyrhynchos_platyrhynchos ENSAPLP00000020704 90.5563 87.8396 ENSG00000174243 homo_sapiens ENSP00000310723 93.9024 90.2439 gallus_gallus ENSGALP00010033430 64.5432 62.0285 ENSG00000174243 homo_sapiens ENSP00000310723 66.8293 66.5854 serinus_canaria ENSSCAP00000019212 99.6364 99.2727 ENSG00000174243 homo_sapiens ENSP00000310723 85.7317 82.8049 parus_major ENSPMJP00000006319 97.2337 93.9142 ENSG00000174243 homo_sapiens ENSP00000310723 98.2927 94.6341 anolis_carolinensis ENSACAP00000021105 94.7121 91.1868 ENSG00000174243 homo_sapiens ENSP00000310723 91.9512 85.7317 neolamprologus_brichardi ENSNBRP00000030144 90.4077 84.2926 ENSG00000174243 homo_sapiens ENSP00000310723 97.561 94.6341 naja_naja ENSNNAP00000017513 98.6436 95.6843 ENSG00000174243 homo_sapiens ENSP00000310723 97.0732 93.4146 podarcis_muralis ENSPMRP00000031294 97.3105 93.643 ENSG00000174243 homo_sapiens ENSP00000310723 93.0488 88.9024 geospiza_fortis ENSGFOP00000010469 83.025 79.3254 ENSG00000174243 homo_sapiens ENSP00000310723 97.9268 95.3659 taeniopygia_guttata ENSTGUP00000028369 98.5276 95.9509 ENSG00000174243 homo_sapiens ENSP00000310723 94.8781 87.9268 erpetoichthys_calabaricus ENSECRP00000017301 95.5774 88.5749 ENSG00000174243 homo_sapiens ENSP00000310723 17.0732 16.5854 erpetoichthys_calabaricus ENSECRP00000028791 93.9597 91.2752 ENSG00000174243 homo_sapiens ENSP00000310723 92.0732 84.8781 kryptolebias_marmoratus ENSKMAP00000016183 92.4113 85.1897 ENSG00000174243 homo_sapiens ENSP00000310723 98.1707 95 salvator_merianae ENSSMRP00000015449 98.0512 94.8843 ENSG00000174243 homo_sapiens ENSP00000310723 92.1951 85.2439 oryzias_javanicus ENSOJAP00000031593 93.7965 86.7246 ENSG00000174243 homo_sapiens ENSP00000310723 86.8293 81.5854 amphilophus_citrinellus ENSACIP00000000024 94.4297 88.7268 ENSG00000174243 homo_sapiens ENSP00000310723 91.9512 84.8781 dicentrarchus_labrax ENSDLAP00005060968 93.7811 86.5672 ENSG00000174243 homo_sapiens ENSP00000310723 91.9512 85.4878 amphiprion_percula ENSAPEP00000023685 94.015 87.4065 ENSG00000174243 homo_sapiens ENSP00000310723 91.4634 83.7805 oryzias_sinensis ENSOSIP00000030190 93.5162 85.6609 ENSG00000174243 homo_sapiens ENSP00000310723 87.561 83.6585 pelodiscus_sinensis ENSPSIP00000002924 94.4737 90.2632 ENSG00000174243 homo_sapiens ENSP00000310723 97.3171 95.1219 gopherus_evgoodei ENSGEVP00005012387 98.155 95.941 ENSG00000174243 homo_sapiens ENSP00000310723 97.439 95 chelonoidis_abingdonii ENSCABP00000009745 98.278 95.818 ENSG00000174243 homo_sapiens ENSP00000310723 92.3171 85.8537 seriola_dumerili ENSSDUP00000031252 93.9206 87.3449 ENSG00000174243 homo_sapiens ENSP00000310723 90.9756 83.5366 cottoperca_gobio ENSCGOP00000018564 93.4837 85.8396 ENSG00000174243 homo_sapiens ENSP00000310723 82.6829 80.7317 struthio_camelus_australis ENSSCUP00000017014 96.034 93.7677 ENSG00000174243 homo_sapiens ENSP00000310723 97.561 95.4878 anser_brachyrhynchus ENSABRP00000004387 84.122 82.3344 ENSG00000174243 homo_sapiens ENSP00000310723 90.1219 82.561 gasterosteus_aculeatus ENSGACP00000003970 93.426 85.5879 ENSG00000174243 homo_sapiens ENSP00000310723 90.8537 83.4146 cynoglossus_semilaevis ENSCSEP00000032669 92.5466 84.9689 ENSG00000174243 homo_sapiens ENSP00000310723 92.6829 85.1219 poecilia_formosa ENSPFOP00000012280 94.176 86.4932 ENSG00000174243 homo_sapiens ENSP00000310723 93.0488 85.8537 myripristis_murdjan ENSMMDP00005000711 94.4307 87.1287 ENSG00000174243 homo_sapiens ENSP00000310723 91.9512 84.0244 sander_lucioperca ENSSLUP00000024386 93.7811 85.6965 ENSG00000174243 homo_sapiens ENSP00000310723 97.9268 95.2439 strigops_habroptila ENSSHBP00005014344 98.2864 95.5936 ENSG00000174243 homo_sapiens ENSP00000310723 91.9512 85.4878 amphiprion_ocellaris ENSAOCP00000012838 93.5484 86.9727 ENSG00000174243 homo_sapiens ENSP00000310723 97.3171 95.2439 terrapene_carolina_triunguis ENSTMTP00000029593 98.2759 96.1823 ENSG00000174243 homo_sapiens ENSP00000310723 64.6341 60.7317 hucho_hucho ENSHHUP00000053095 95.6679 89.8917 ENSG00000174243 homo_sapiens ENSP00000310723 18.5366 16.2195 hucho_hucho ENSHHUP00000059197 71.3615 62.4413 ENSG00000174243 homo_sapiens ENSP00000310723 91.7073 84.7561 betta_splendens ENSBSLP00000024709 94 86.875 ENSG00000174243 homo_sapiens ENSP00000310723 85.3659 80 pygocentrus_nattereri ENSPNAP00000013346 94.2127 88.2907 ENSG00000174243 homo_sapiens ENSP00000310723 91.9512 85.6098 anabas_testudineus ENSATEP00000069797 93.5484 87.0968 ENSG00000174243 homo_sapiens ENSP00000310723 67.9268 55.8537 ciona_savignyi ENSCSAVP00000006945 82.8869 68.1548 ENSG00000174243 homo_sapiens ENSP00000310723 43.4146 28.7805 saccharomyces_cerevisiae YDR243C 60.5442 40.1361 ENSG00000174243 homo_sapiens ENSP00000310723 92.3171 85.8537 seriola_lalandi_dorsalis ENSSLDP00000013125 93.9206 87.3449 ENSG00000174243 homo_sapiens ENSP00000310723 91.5854 84.1463 labrus_bergylta ENSLBEP00000025493 93.875 86.25 ENSG00000174243 homo_sapiens ENSP00000310723 91.5854 85.3659 pundamilia_nyererei ENSPNYP00000027966 90.2644 84.1346 ENSG00000174243 homo_sapiens ENSP00000310723 91.7073 85.4878 mastacembelus_armatus ENSMAMP00000035961 93.3002 86.9727 ENSG00000174243 homo_sapiens ENSP00000310723 92.0732 85.1219 stegastes_partitus ENSSPAP00000021814 93.6725 86.6005 ENSG00000174243 homo_sapiens ENSP00000310723 24.3902 23.0488 oncorhynchus_tshawytscha ENSOTSP00005020014 80.3213 75.9036 ENSG00000174243 homo_sapiens ENSP00000310723 90.4878 81.3415 oncorhynchus_tshawytscha ENSOTSP00005051962 91.0429 81.8405 ENSG00000174243 homo_sapiens ENSP00000310723 91.9512 85.4878 acanthochromis_polyacanthus ENSAPOP00000002371 93.5484 86.9727 ENSG00000174243 homo_sapiens ENSP00000310723 92.3171 90.1219 aquila_chrysaetos_chrysaetos ENSACCP00020011394 96.927 94.6223 ENSG00000174243 homo_sapiens ENSP00000310723 92.1951 85.3659 nothobranchius_furzeri ENSNFUP00015045673 94.2643 87.2818 ENSG00000174243 homo_sapiens ENSP00000310723 92.3171 85.4878 cyprinodon_variegatus ENSCVAP00000013230 94.389 87.4065 ENSG00000174243 homo_sapiens ENSP00000310723 94.0244 86.5854 denticeps_clupeoides ENSDCDP00000048843 95.3028 87.7627 ENSG00000174243 homo_sapiens ENSP00000310723 92.6829 85.4878 larimichthys_crocea ENSLCRP00005016971 93.8272 86.5432 ENSG00000174243 homo_sapiens ENSP00000310723 91.7073 84.5122 takifugu_rubripes ENSTRUP00000076683 91.9315 84.7188 ENSG00000174243 homo_sapiens ENSP00000310723 90.1219 87.0732 ficedula_albicollis ENSFALP00000000144 96.6013 93.3333 ENSG00000174243 homo_sapiens ENSP00000310723 91.4634 84.3902 hippocampus_comes ENSHCOP00000027458 93.3997 86.1768 ENSG00000174243 homo_sapiens ENSP00000310723 92.1951 83.6585 cyprinus_carpio_carpio ENSCCRP00000128235 92.8747 84.2752 ENSG00000174243 homo_sapiens ENSP00000310723 93.6585 85 cyprinus_carpio_carpio ENSCCRP00000137862 94.5813 85.8374 ENSG00000174243 homo_sapiens ENSP00000310723 75 71.2195 coturnix_japonica ENSCJPP00005002778 90.9763 86.3905 ENSG00000174243 homo_sapiens ENSP00000310723 92.561 85 poecilia_latipinna ENSPLAP00000021346 94.403 86.6915 ENSG00000174243 homo_sapiens ENSP00000310723 62.1951 59.0244 sinocyclocheilus_grahami ENSSGRP00000086075 97.7011 92.7203 ENSG00000174243 homo_sapiens ENSP00000310723 18.1707 16.5854 sinocyclocheilus_grahami ENSSGRP00000086077 87.1345 79.5322 ENSG00000174243 homo_sapiens ENSP00000310723 93.0488 84.5122 sinocyclocheilus_grahami ENSSGRP00000075810 94.5477 85.8736 ENSG00000174243 homo_sapiens ENSP00000310723 91.8293 85.6098 maylandia_zebra ENSMZEP00005034881 93.4243 87.0968 ENSG00000174243 homo_sapiens ENSP00000310723 39.6341 38.0488 tetraodon_nigroviridis ENSTNIP00000022860 97.5976 93.6937 ENSG00000174243 homo_sapiens ENSP00000310723 94.1463 86.2195 paramormyrops_kingsleyae ENSPKIP00000008748 94.3765 86.4303 ENSG00000174243 homo_sapiens ENSP00000310723 94.0244 86.5854 scleropages_formosus ENSSFOP00015020621 94.4853 87.0098 ENSG00000174243 homo_sapiens ENSP00000310723 93.6585 89.3902 leptobrachium_leishanense ENSLLEP00000007434 95.0495 90.7178 ENSG00000174243 homo_sapiens ENSP00000310723 91.5854 83.1707 scophthalmus_maximus ENSSMAP00000000858 93.7578 85.1436 ENSG00000174243 homo_sapiens ENSP00000310723 91.9512 85.1219 oryzias_melastigma ENSOMEP00000005434 93.5484 86.6005
Go ID
Go term
No. evidence
Entries
Species
Category
GO:0000354 involved_in cis assembly of pre-catalytic spliceosome 1 IC Homo_sapiens(9606) Process GO:0000375 involved_in RNA splicing, via transesterification reactions 1 TAS Homo_sapiens(9606) Process GO:0000398 involved_in mRNA splicing, via spliceosome 4 IBA,IC,NAS,TAS Homo_sapiens(9606) Process GO:0000785 part_of chromatin 1 IDA Homo_sapiens(9606) Component GO:0003723 enables RNA binding 2 HDA,IBA Homo_sapiens(9606) Function GO:0003724 enables RNA helicase activity 1 TAS Homo_sapiens(9606) Function GO:0004386 NOT enables helicase activity 1 IDA Homo_sapiens(9606) Function GO:0005515 enables protein binding 1 IPI Homo_sapiens(9606) Function GO:0005524 enables ATP binding 1 IEA Homo_sapiens(9606) Function GO:0005634 located_in nucleus 2 IDA,NAS Homo_sapiens(9606) Component GO:0005654 located_in nucleoplasm 2 IDA,TAS Homo_sapiens(9606) Component GO:0005682 part_of U5 snRNP 1 IDA Homo_sapiens(9606) Component GO:0005730 located_in nucleolus 1 IDA Homo_sapiens(9606) Component GO:0008380 involved_in RNA splicing 1 TAS Homo_sapiens(9606) Process GO:0016887 enables ATP hydrolysis activity 1 IEA Homo_sapiens(9606) Function GO:0046540 part_of U4/U6 x U5 tri-snRNP complex 2 IDA,IPI Homo_sapiens(9606) Component GO:0062176 involved_in R-loop processing 1 IDA Homo_sapiens(9606) Process GO:0070062 located_in extracellular exosome 1 HDA Homo_sapiens(9606) Component GO:0071013 part_of catalytic step 2 spliceosome 2 IBA,IDA Homo_sapiens(9606) Component
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