RBPWorld - a comprehensive database of RNA Binding Proteins

Functions and Diseases

RBP Type	Canonical_RBPs
Diseases	CancerSARS-COV-OC43SARS-COV-2
Drug	N.A.
Main interacting RNAs	N.A.
Moonlighting functions	N.A.
Localizations	Nucleoli
BulkPerturb-seq	DataSet_01_169

Description

Ensembl ID	ENSG00000173545	Gene ID	90441	Accession	30958
Symbol	ZNF622	Alias	ZPR9	Full Name	zinc finger protein 622
Status	Confidence	Length	14282 bases	Strand	Minus strand
Position	5 : 16451519 - 16465800	RNA binding domain	zf-C2H2_jaz , zf-met
Summary	Enables RNA binding activity. Involved in several processes, including intrinsic apoptotic signaling pathway in response to oxidative stress; positive regulation of JNK cascade; and positive regulation of kinase activity. Located in Golgi apparatus; cytosol; and nuclear lumen. [provided by Alliance of Genome Resources, Apr 2022]

RNA binding domains (RBDs)

Search:

Protein	Domain	Pfam ID	E-value	Domain number
ENSP00000310042	zf-C2H2_jaz	PF12171	2e-09	1
ENSP00000310042	zf-met	PF12874	0.00051	2

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RNA binding proteomes (RBPomes)

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Pubmed ID	Full Name	Cell	Author	Time	Doi
22658674	RIC_PMID22658674_Hs_HeLa	HeLa	Alfredo Castello?	2012 Jun 8	doi: 10.1016/j.cell.2012.04.031.?Epub 2012 May 31
25173706	Pclap_PMID25173706_Hs_HEK293	HEK293	Katharina Kramer	2014 Oct;11	doi: 10.1038/nmeth.3092.?Epub 2014 Aug 31
30352994	eRIC_PMID30352994_Hs_JURKAT.2018	JURKAT	Joel I Perez-Perri	2018 Oct 23	doi: 10.1038/s41467-018-06557-8
30352994	RIC_PMID30352994_Hs_JURKAT.2018	JURKAT	Joel I Perez-Perri	2018 Oct 23	doi: 10.1038/s41467-018-06557-8
30528433	XRNAX_PMID30528433_Hs_HEK293	HEK293	Jakob Trendel	2019 Jan 10	doi: 10.1016/j.cell.2018.11.004.?Epub 2018 Dec 6
30528433	XRNAX_PMID30528433_Hs_HeLa	HeLa	Jakob Trendel	2019 Jan 10	doi: 10.1016/j.cell.2018.11.004.?Epub 2018 Dec 6
30528433	XRNAX_PMID30528433_Hs_MCF7	MCF7	Jakob Trendel	2019 Jan 10	doi: 10.1016/j.cell.2018.11.004.?Epub 2018 Dec 6
30528433	XRNAX_PMID30528433._Hs.MCF7.ars.	MCF7	Jakob Trendel	2019 Jan 10	doi: 10.1016/j.cell.2018.11.004.?Epub 2018 Dec 6
30607034	RIC_PMID_30607034_Hs_HEK293	HEK293	Rayner M L Queiroz	2019 Feb	doi: 10.1038/s41587-018-0001-2.?Epub 2019 Jan 3
30799147	cRIC_PMID30799147_Hs_HEK293.cRIC.SINV	HEK293	Manuel Garcia-Moreno	2019 Apr 4	doi: 10.1016/j.molcel.2019.01.017.?Epub 2019 Feb 21

Showing 1 to 10 of 16 entries

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Literatures on RNA binding capacity

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Pubmed ID	Title	Author	Time	Journal
35229157	Unheeded SARS-CoV-2 proteins? A deep look into negative-sense RNA.	Martin Bartas	2022-05-13	Briefings in bioinformatics

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Transcripts

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Name	Transcript ID	bp	Protein	Translation ID
ZNF622-201	ENST00000308683	1707	477aa	ENSP00000310042

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Gene Model

Click here to download ENSG00000173545's gene model file

Phenotypes

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ensgID	Trait	pValue	Pubmed ID
13163	Diabetic Nephropathies	3.6000000E-005	16775037
57194	Dextroamphetamine	6.1935000E-005	-
57197	Dextroamphetamine	4.8223000E-005	-

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ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID
No data available in table

Protein-Protein Interaction (PPI)

Click here to download ENSG00000173545's PPI file

Orthologs

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Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
ENSG00000173545	homo_sapiens	ENSP00000310042	98.1132	97.4843	nomascus_leucogenys	ENSNLEP00000014439	98.1132	97.4843
ENSG00000173545	homo_sapiens	ENSP00000310042	98.9518	98.9518	pan_paniscus	ENSPPAP00000010182	98.9518	98.9518
ENSG00000173545	homo_sapiens	ENSP00000310042	99.1614	98.1132	pongo_abelii	ENSPPYP00000024261	99.1614	98.1132
ENSG00000173545	homo_sapiens	ENSP00000310042	98.7421	98.7421	pan_troglodytes	ENSPTRP00000028727	98.9496	98.9496
ENSG00000173545	homo_sapiens	ENSP00000310042	99.5807	99.1614	gorilla_gorilla	ENSGGOP00000018732	99.1649	98.7474
ENSG00000173545	homo_sapiens	ENSP00000310042	81.3417	70.2306	ornithorhynchus_anatinus	ENSOANP00000014555	83.4409	72.043
ENSG00000173545	homo_sapiens	ENSP00000310042	88.26	80.7128	sarcophilus_harrisii	ENSSHAP00000004925	90.1499	82.4411
ENSG00000173545	homo_sapiens	ENSP00000310042	83.4382	76.3103	notamacropus_eugenii	ENSMEUP00000004007	84.322	77.1186
ENSG00000173545	homo_sapiens	ENSP00000310042	93.501	89.9371	choloepus_hoffmanni	ENSCHOP00000009071	94.2918	90.6977
ENSG00000173545	homo_sapiens	ENSP00000310042	94.3396	90.1468	dasypus_novemcinctus	ENSDNOP00000025609	94.5378	90.3361

Showing 1 to 10 of 215 entries

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Gene Ontology

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Go ID	Go term	No. evidence	Entries	Species	Category
GO:0042273	involved_in ribosomal large subunit biogenesis	2	IBA,IDA	Homo_sapiens(9606)	Process
GO:0003723	enables RNA binding	1	HDA	Homo_sapiens(9606)	Function
GO:0005515	enables protein binding	1	IPI	Homo_sapiens(9606)	Function
GO:0005654	located_in nucleoplasm	1	IDA	Homo_sapiens(9606)	Component
GO:0005730	located_in nucleolus	1	IDA	Homo_sapiens(9606)	Component
GO:0005794	located_in Golgi apparatus	1	IDA	Homo_sapiens(9606)	Component
GO:0005829	located_in cytosol	1	IDA	Homo_sapiens(9606)	Component
GO:0008270	enables zinc ion binding	1	IEA	Homo_sapiens(9606)	Function
GO:0008631	involved_in intrinsic apoptotic signaling pathway in response to oxidative stress	1	IDA	Homo_sapiens(9606)	Process
GO:0030687	part_of preribosome, large subunit precursor	1	IBA	Homo_sapiens(9606)	Component

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Welcome to

RBP World!

Functions and Diseases

Description

RNA binding domains (RBDs)

RNA binding proteomes (RBPomes)

Literatures on RNA binding capacity

Transcripts

Gene Model

Pathways

Phenotypes

GWAS

Protein-Protein Interaction (PPI)

Paralogs

Orthologs

Gene Ontology

Expression