Functions and Diseases

RBP Type Non-canonical_RBPs
Diseases Cancer
Drug N.A.
Main interacting RNAs N.A.
Moonlighting functions Transmemebrane
Localizations N.A.
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000170439 Gene ID 196410 Accession 28276
Symbol TMT1B Alias ALDI;METTL7B Full Name thiol methyltransferase 1B
Status Confidence Length 2876 bases Strand Plus strand
Position 12 : 55681736 - 55684611 RNA binding domain N.A.
Summary Enables thiol S-methyltransferase activity. Predicted to be involved in methylation. [provided by Alliance of Genome Resources, Apr 2022]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000377796 Methyltransf_31 PF13847 7.3e-11 1

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal

Transcripts

Name Transcript ID bp Protein Translation ID
METTL7B-201 ENST00000394252 1316 244aa ENSP00000377796

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000170439homo_sapiensENSP0000035889621.866713.3333homo_sapiensENSP0000037779633.606620.4918
ENSG00000170439homo_sapiensENSP0000029787322.857111.0204homo_sapiensENSP0000037779622.950811.0656
ENSG00000170439homo_sapiensENSP000003317877557.377homo_sapiensENSP000003777967557.377
ENSG00000170439homo_sapiensENSP0000028853226.605516.208homo_sapiensENSP0000037779635.655721.7213

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000170439homo_sapiensENSP0000037779610098.7705nomascus_leucogenysENSNLEP0000002137610098.7705
ENSG00000170439homo_sapiensENSP00000377796100100pan_paniscusENSPPAP00000013118100100
ENSG00000170439homo_sapiensENSP0000037779699.180397.1311pongo_abeliiENSPPYP0000000527187.681285.8696
ENSG00000170439homo_sapiensENSP00000377796100100pan_troglodytesENSPTRP00000008603100100
ENSG00000170439homo_sapiensENSP00000377796100100gorilla_gorillaENSGGOP00000008388100100
ENSG00000170439homo_sapiensENSP0000037779688.934479.0984notamacropus_eugeniiENSMEUP0000000036088.934479.0984
ENSG00000170439homo_sapiensENSP0000037779693.032889.3443dasypus_novemcinctusENSDNOP0000002660993.032889.3443
ENSG00000170439homo_sapiensENSP0000037779671.721365.1639echinops_telfairiENSETEP0000000738190.206281.9588
ENSG00000170439homo_sapiensENSP0000037779693.852590.9836callithrix_jacchusENSCJAP0000001514683.272780.7273
ENSG00000170439homo_sapiensENSP0000037779697.54195.4918cercocebus_atysENSCATP0000003655997.54195.4918
ENSG00000170439homo_sapiensENSP0000037779697.54195.4918macaca_fascicularisENSMFAP0000004071597.54195.4918
ENSG00000170439homo_sapiensENSP0000037779697.54195.9016macaca_mulattaENSMMUP0000007505097.54195.9016
ENSG00000170439homo_sapiensENSP0000037779697.54195.4918macaca_nemestrinaENSMNEP0000001138897.54195.4918
ENSG00000170439homo_sapiensENSP0000037779697.54195.4918papio_anubisENSPANP0000000055786.231984.4203
ENSG00000170439homo_sapiensENSP0000037779697.131194.6721mandrillus_leucophaeusENSMLEP0000001853897.131194.6721
ENSG00000170439homo_sapiensENSP0000037779694.672188.1148tursiops_truncatusENSTTRP0000000910394.672188.1148
ENSG00000170439homo_sapiensENSP0000037779692.622986.8852vulpes_vulpesENSVVUP0000003296092.622986.8852
ENSG00000170439homo_sapiensENSP0000037779692.213184.0164mus_spretusMGP_SPRETEiJ_P002651992.213184.0164
ENSG00000170439homo_sapiensENSP0000037779692.622985.6557equus_asinusENSEASP0000505313792.622985.6557
ENSG00000170439homo_sapiensENSP0000037779693.442687.2951capra_hircusENSCHIP0000003367893.442687.2951
ENSG00000170439homo_sapiensENSP0000037779692.622985.2459loxodonta_africanaENSLAFP0000001845192.622985.2459
ENSG00000170439homo_sapiensENSP0000037779693.852588.9344panthera_leoENSPLOP0000000841393.852588.9344
ENSG00000170439homo_sapiensENSP0000037779691.393484.8361ailuropoda_melanoleucaENSAMEP0000001254691.393484.8361
ENSG00000170439homo_sapiensENSP0000037779693.032885.6557bos_indicus_hybridENSBIXP0000501181393.032885.6557
ENSG00000170439homo_sapiensENSP0000037779691.393487.2951oryctolagus_cuniculusENSOCUP0000002425291.393487.2951
ENSG00000170439homo_sapiensENSP0000037779692.213185.6557equus_caballusENSECAP0000000951292.213185.6557
ENSG00000170439homo_sapiensENSP0000037779692.622987.2951canis_lupus_familiarisENSCAFP0084500733992.622987.2951
ENSG00000170439homo_sapiensENSP0000037779693.852588.9344panthera_pardusENSPPRP0000000280193.852588.9344
ENSG00000170439homo_sapiensENSP0000037779693.852589.3443marmota_marmota_marmotaENSMMMP0000001621293.852589.3443
ENSG00000170439homo_sapiensENSP0000037779694.672188.5246balaenoptera_musculusENSBMSP0001001305794.672188.5246
ENSG00000170439homo_sapiensENSP0000037779689.344382.7869cavia_porcellusENSCPOP0000001349489.344382.7869
ENSG00000170439homo_sapiensENSP0000037779693.442688.5246felis_catusENSFCAP0000002778893.442688.5246
ENSG00000170439homo_sapiensENSP0000037779690.573884.8361ursus_americanusENSUAMP0000001910490.573884.8361
ENSG00000170439homo_sapiensENSP0000037779670.08259.4262monodelphis_domesticaENSMODP0000000210965.517255.5556
ENSG00000170439homo_sapiensENSP0000037779693.032886.0656bison_bison_bisonENSBBBP0000000584593.032886.0656
ENSG00000170439homo_sapiensENSP0000037779693.852587.2951monodon_monocerosENSMMNP0001502355294.238787.6543
ENSG00000170439homo_sapiensENSP0000037779692.213184.4262sus_scrofaENSSSCP0000003217592.213184.4262
ENSG00000170439homo_sapiensENSP0000037779691.803386.8852octodon_degusENSODEP0000000626991.803386.8852
ENSG00000170439homo_sapiensENSP0000037779693.852586.8852jaculus_jaculusENSJJAP0000001264393.852586.8852
ENSG00000170439homo_sapiensENSP0000037779693.442688.1148ovis_aries_rambouilletENSOARP0002000899493.442688.1148
ENSG00000170439homo_sapiensENSP0000037779690.573884.8361ursus_maritimusENSUMAP0000002108390.573884.8361
ENSG00000170439homo_sapiensENSP0000037779694.262387.7049delphinapterus_leucasENSDLEP0000000889994.262387.7049
ENSG00000170439homo_sapiensENSP0000037779693.852587.2951physeter_catodonENSPCTP0000501081193.852587.2951
ENSG00000170439homo_sapiensENSP0000037779692.213183.6066mus_caroliMGP_CAROLIEiJ_P002521992.213183.6066
ENSG00000170439homo_sapiensENSP0000037779691.803383.6066mus_musculusENSMUSP0000002639891.803383.6066
ENSG00000170439homo_sapiensENSP0000037779689.344381.1475dipodomys_ordiiENSDORP0000001330089.344381.1475
ENSG00000170439homo_sapiensENSP0000037779691.803386.0656mustela_putorius_furoENSMPUP0000000084891.803386.0656
ENSG00000170439homo_sapiensENSP0000037779694.672192.2131aotus_nancymaaeENSANAP0000003801894.672192.2131
ENSG00000170439homo_sapiensENSP0000037779695.491893.8525saimiri_boliviensis_boliviensisENSSBOP0000000255795.491893.8525
ENSG00000170439homo_sapiensENSP0000037779694.262389.7541vicugna_pacosENSVPAP0000000884494.262389.7541
ENSG00000170439homo_sapiensENSP0000037779697.54195.9016chlorocebus_sabaeusENSCSAP0000000164997.54195.9016
ENSG00000170439homo_sapiensENSP0000037779675.819773.3607tupaia_belangeriENSTBEP0000001351195.360892.268
ENSG00000170439homo_sapiensENSP0000037779692.622984.4262mesocricetus_auratusENSMAUP0000001599492.622984.4262
ENSG00000170439homo_sapiensENSP0000037779694.262387.7049phocoena_sinusENSPSNP0000001715094.262387.7049
ENSG00000170439homo_sapiensENSP0000037779672.131163.9344camelus_dromedariusENSCDRP0000500560773.640265.272
ENSG00000170439homo_sapiensENSP0000037779673.360765.1639camelus_dromedariusENSCDRP0000501149274.895466.5272
ENSG00000170439homo_sapiensENSP0000037779694.672190.9836carlito_syrichtaENSTSYP0000000733094.285790.6122
ENSG00000170439homo_sapiensENSP0000037779693.852588.5246panthera_tigris_altaicaENSPTIP0000001286793.852588.5246
ENSG00000170439homo_sapiensENSP0000037779692.622983.6066rattus_norvegicusENSRNOP0000001076092.622983.6066
ENSG00000170439homo_sapiensENSP0000037779624.590222.1311prolemur_simusENSPSMP0000003503185.714377.1429
ENSG00000170439homo_sapiensENSP0000037779690.573880.7377microtus_ochrogasterENSMOCP0000000837290.573880.7377
ENSG00000170439homo_sapiensENSP0000037779692.213184.0164peromyscus_maniculatus_bairdiiENSPEMP0000000185592.213184.0164
ENSG00000170439homo_sapiensENSP0000037779692.213185.6557bos_mutusENSBMUP0000002463492.213185.6557
ENSG00000170439homo_sapiensENSP0000037779691.803383.6066mus_spicilegusENSMSIP0000003394291.803383.6066
ENSG00000170439homo_sapiensENSP0000037779693.442684.0164cricetulus_griseus_chok1gshdENSCGRP0000102141493.442684.0164
ENSG00000170439homo_sapiensENSP0000037779689.344381.5574pteropus_vampyrusENSPVAP0000001674088.259180.5668
ENSG00000170439homo_sapiensENSP0000037779687.295175.8197vombatus_ursinusENSVURP0001003107387.295175.8197
ENSG00000170439homo_sapiensENSP0000037779693.032888.9344rhinolophus_ferrumequinumENSRFEP0001000929872.990469.7749
ENSG00000170439homo_sapiensENSP0000037779690.983686.0656neovison_visonENSNVIP0000002799082.835878.3582
ENSG00000170439homo_sapiensENSP0000037779693.032885.6557bos_taurusENSBTAP0000001714193.032885.6557
ENSG00000170439homo_sapiensENSP0000037779671.721361.8852heterocephalus_glaber_femaleENSHGLP0000003181558.724850.6711
ENSG00000170439homo_sapiensENSP0000037779697.131194.6721rhinopithecus_bietiENSRBIP0000000932897.131194.6721
ENSG00000170439homo_sapiensENSP0000037779691.803386.4754canis_lupus_dingoENSCAFP0002003365184.848579.9242
ENSG00000170439homo_sapiensENSP0000037779695.491890.1639sciurus_vulgarisENSSVLP0000500256085.34880.5861
ENSG00000170439homo_sapiensENSP0000037779695.08290.1639sciurus_vulgarisENSSVLP0000500235695.08290.1639
ENSG00000170439homo_sapiensENSP0000037779688.524679.0984phascolarctos_cinereusENSPCIP0000003323188.163378.7755
ENSG00000170439homo_sapiensENSP0000037779692.622984.0164procavia_capensisENSPCAP0000000835692.622984.0164
ENSG00000170439homo_sapiensENSP0000037779694.262386.8852nannospalax_galiliENSNGAP0000001849894.262386.8852
ENSG00000170439homo_sapiensENSP0000037779692.213185.6557bos_grunniensENSBGRP0000001342192.213185.6557
ENSG00000170439homo_sapiensENSP0000037779690.983686.8852chinchilla_lanigeraENSCLAP0000002411090.983686.8852
ENSG00000170439homo_sapiensENSP0000037779693.032886.4754cervus_hanglu_yarkandensisENSCHYP0000001193193.032886.4754
ENSG00000170439homo_sapiensENSP0000037779690.573886.0656catagonus_wagneriENSCWAP0000001087485.992281.7121
ENSG00000170439homo_sapiensENSP0000037779695.901691.8033otolemur_garnettiiENSOGAP0000000940995.901691.8033
ENSG00000170439homo_sapiensENSP0000037779695.08293.4426cebus_imitatorENSCCAP0000002136491.338689.7638
ENSG00000170439homo_sapiensENSP0000037779669.262363.9344urocitellus_parryiiENSUPAP0001001865274.778869.0266
ENSG00000170439homo_sapiensENSP0000037779691.803383.1967moschus_moschiferusENSMMSP0000001643991.803383.1967
ENSG00000170439homo_sapiensENSP0000037779697.131194.6721rhinopithecus_roxellanaENSRROP0000004084497.131194.6721
ENSG00000170439homo_sapiensENSP0000037779691.393482.7869mus_pahariMGP_PahariEiJ_P008745191.393482.7869
ENSG00000170439homo_sapiensENSP0000037779677.868970.4918propithecus_coquereliENSPCOP0000001874888.372180
ENSG00000170439homo_sapiensENSP0000037779627.049213.9344caenorhabditis_elegansR08F11.4.118.64419.60452
ENSG00000170439homo_sapiensENSP0000037779627.45914.3443caenorhabditis_elegansK12D9.1.118.92669.88701
ENSG00000170439homo_sapiensENSP0000037779626.639313.1148caenorhabditis_elegansR08E5.3.117.80828.76712
ENSG00000170439homo_sapiensENSP0000037779625.819712.2951caenorhabditis_elegansR08E5.1a.119.87389.46372
ENSG00000170439homo_sapiensENSP0000037779619.67217.37705caenorhabditis_elegansZK622.3b.19.917363.71901
ENSG00000170439homo_sapiensENSP0000037779622.950812.2951ciona_intestinalisENSCINP0000001849323.931612.8205
ENSG00000170439homo_sapiensENSP0000037779622.54112.2951ciona_intestinalisENSCINP0000002513623.404312.766
ENSG00000170439homo_sapiensENSP0000037779618.44268.19672ciona_intestinalisENSCINP0000003024620.17948.96861
ENSG00000170439homo_sapiensENSP0000037779626.229513.5246ciona_intestinalisENSCINP0000003579523.188411.9565
ENSG00000170439homo_sapiensENSP0000037779624.180312.7049ciona_intestinalisENSCINP0000003248327.188914.2857
ENSG00000170439homo_sapiensENSP0000037779625.409814.3443ciona_intestinalisENSCINP0000002265222.96312.963
ENSG00000170439homo_sapiensENSP0000037779625.409812.2951ciona_intestinalisENSCINP0000003137522.064110.6762
ENSG00000170439homo_sapiensENSP0000037779621.721312.2951ciona_intestinalisENSCINP0000003183021.810712.3457
ENSG00000170439homo_sapiensENSP0000037779625.409814.3443ciona_intestinalisENSCINP0000002265322.064112.4555
ENSG00000170439homo_sapiensENSP0000037779621.311512.2951ciona_intestinalisENSCINP0000003648029.885117.2414
ENSG00000170439homo_sapiensENSP0000037779624.590214.3443ciona_intestinalisENSCINP0000003365924.691414.4033
ENSG00000170439homo_sapiensENSP0000037779623.360713.9344ciona_intestinalisENSCINP0000003417023.553714.0496
ENSG00000170439homo_sapiensENSP0000037779624.590212.2951ciona_intestinalisENSCINP0000001054424.096412.0482
ENSG00000170439homo_sapiensENSP0000037779621.311510.6557ciona_intestinalisENSCINP0000003281522.317611.1588
ENSG00000170439homo_sapiensENSP0000037779625.409810.6557ciona_intestinalisENSCINP0000000961227.678611.6071
ENSG00000170439homo_sapiensENSP0000037779653.278736.4754callorhinchus_miliiENSCMIP0000000581263.725543.6275
ENSG00000170439homo_sapiensENSP000003777966.147543.27869latimeria_chalumnaeENSLACP000000002306.302523.36134
ENSG00000170439homo_sapiensENSP0000037779638.114825.8197salmo_truttaENSSTUP0000001925058.860839.8734
ENSG00000170439homo_sapiensENSP0000037779665.163951.2295gadus_morhuaENSGMOP0000000283265.432151.4403
ENSG00000170439homo_sapiensENSP0000037779653.278738.9344cottoperca_gobioENSCGOP0000004545551.792837.8486
ENSG00000170439homo_sapiensENSP0000037779650.409839.7541anser_brachyrhynchusENSABRP0000002432767.955853.5912
ENSG00000170439homo_sapiensENSP0000037779665.573849.1803cynoglossus_semilaevisENSCSEP0000000494965.573849.1803
ENSG00000170439homo_sapiensENSP0000037779617.6238.60656ciona_savignyiENSCSAVP0000000728319.90749.72222
ENSG00000170439homo_sapiensENSP0000037779623.770513.1148ciona_savignyiENSCSAVP0000000557323.212.8
ENSG00000170439homo_sapiensENSP0000037779622.95089.83607ciona_savignyiENSCSAVP0000001117625.454510.9091
ENSG00000170439homo_sapiensENSP0000037779625.409812.7049saccharomyces_cerevisiaeYHR209W21.305810.6529
ENSG00000170439homo_sapiensENSP0000037779621.31159.01639saccharomyces_cerevisiaeYER175C17.39137.35786
ENSG00000170439homo_sapiensENSP0000037779639.344322.9508saccharomyces_cerevisiaeYDR316W20.382211.8896
ENSG00000170439homo_sapiensENSP0000037779664.754152.459scophthalmus_maximusENSSMAP0000006001264.754152.459

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0005789located_in endoplasmic reticulum membrane1IEAHomo_sapiens(9606)Component
GO:0005811located_in lipid droplet1IEAHomo_sapiens(9606)Component
GO:0008168enables methyltransferase activity1IBAHomo_sapiens(9606)Function
GO:0008757enables S-adenosylmethionine-dependent methyltransferase activity1IMPHomo_sapiens(9606)Function
GO:0018708enables thiol S-methyltransferase activity1IMPHomo_sapiens(9606)Function
GO:0032259involved_in methylation1IEAHomo_sapiens(9606)Process

Expression