Functions and Diseases

RBP Type Non-canonical_RBPs
Diseases CancerSARS-COV-2
Drug N.A.
Main interacting RNAs N.A.
Moonlighting functions N.A.
Localizations P-body
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000170027 Gene ID 7532 Accession 12852
Symbol YWHAG Alias DEE56;EIEE56;PPP1R170;14-3-3GAMMA Full Name tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma
Status Confidence Length 32193 bases Strand Minus strand
Position 7 : 76326799 - 76358991 RNA binding domain N.A.
Summary This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the rat ortholog. It is induced by growth factors in human vascular smooth muscle cells, and is also highly expressed in skeletal and heart muscles, suggesting an important role for this protein in muscle tissue. It has been shown to interact with RAF1 and protein kinase C, proteins involved in various signal transduction pathways. [provided by RefSeq, Jul 2008]

RNA binding proteomes (RBPomes)

Literatures on RNA binding capacity

Transcripts

Phenotypes

GWAS

Protein-Protein Interaction (PPI)

Paralogs

Orthologs

Gene Ontology

Expression