Functions and Diseases

RBP Type Canonical_RBPs
Diseases Cancer
Drug N.A.
Main interacting RNAs N.A.
Moonlighting functions TF
Localizations Nucleoli
BulkPerturb-seq DataSet_02_89

Description

Ensembl ID ENSG00000169554 Gene ID 9839 Accession 14881
Symbol ZEB2 Alias SIP1;SIP-1;ZFHX1B;HSPC082;SMADIP1 Full Name zinc finger E-box binding homeobox 2
Status Confidence Length 156694 bases Strand Minus strand
Position 2 : 144364364 - 144521057 RNA binding domain zf-met
Summary The protein encoded by this gene is a member of the Zfh1 family of 2-handed zinc finger/homeodomain proteins. It is located in the nucleus and functions as a DNA-binding transcriptional repressor that interacts with activated SMADs. Mutations in this gene are associated with Hirschsprung disease/Mowat-Wilson syndrome. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Jan 2010]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000490141 zf-met PF12874 7.5e-07 1
ENSP00000490141 zf-met PF12874 7.5e-07 2
ENSP00000490508 zf-met PF12874 7.5e-07 1
ENSP00000490508 zf-met PF12874 7.5e-07 2
ENSP00000490673 zf-met PF12874 7.5e-07 1
ENSP00000490673 zf-met PF12874 7.5e-07 2
ENSP00000490723 zf-met PF12874 7.5e-07 1
ENSP00000490723 zf-met PF12874 7.5e-07 2
ENSP00000490872 zf-met PF12874 7.5e-07 1
ENSP00000490872 zf-met PF12874 7.5e-07 2
ENSP00000490776 zf-met PF12874 9.9e-07 1
ENSP00000490776 zf-met PF12874 9.9e-07 2
ENSP00000443792 zf-met PF12874 1.4e-06 1
ENSP00000443792 zf-met PF12874 1.4e-06 2
ENSP00000302501 zf-met PF12874 1.7e-06 1
ENSP00000302501 zf-met PF12874 1.7e-06 2
ENSP00000386854 zf-met PF12874 1.7e-06 1
ENSP00000386854 zf-met PF12874 1.7e-06 2
ENSP00000454157 zf-met PF12874 1.7e-06 1
ENSP00000454157 zf-met PF12874 1.7e-06 2
ENSP00000487174 zf-met PF12874 1.7e-06 1
ENSP00000487174 zf-met PF12874 1.7e-06 2
ENSP00000490317 zf-met PF12874 2e-06 1
ENSP00000490317 zf-met PF12874 2e-06 2
ENSP00000490293 zf-met PF12874 2e-05 1
ENSP00000376601 zf-met PF12874 2.1e-05 1
ENSP00000376601 zf-met PF12874 2.1e-05 2
ENSP00000395496 zf-met PF12874 4.7e-05 1
ENSP00000475553 zf-met PF12874 0.00021 1
ENSP00000475553 zf-met PF12874 0.00021 2
ENSP00000490934 zf-met PF12874 0.00021 1
ENSP00000490934 zf-met PF12874 0.00021 2
ENSP00000394777 zf-met PF12874 0.0008 1
ENSP00000502467 zf-met PF12874 0.0018 1

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal
26136338 Role and prognostic significance of the epithelial-mesenchymal transition factor ZEB2 in ovarian cancer. Silvia Prislei 2015-08-07 Oncotarget
22000016 In vivo identification of tumor- suppressive PTEN ceRNAs in an oncogenic BRAF-induced mouse model of melanoma. A Florian Karreth 2011-10-14 Cell
36100056 Silencing of RNA binding protein, ZFP36L1, promotes epithelial-mesenchymal transition in liver cancer cells by regulating transcription factor ZEB2. Jian Chen 2022-09-12 Cellular signalling
32700753 Long non‑coding RNA ZEB2‑AS1 affects cell proliferation and apoptosis via the miR‑122‑5p/PLK1 axis in acute myeloid leukemia. Jianmin Guan 2020-10-01 International journal of molecular medicine
30950191 Overexpression of ZEB2-AS1 promotes epithelial-to-mesenchymal transition and metastasis by stabilizing ZEB2 mRNA in head neck squamous cell carcinoma. Pengfei Diao 2019-06-01 Journal of cellular and molecular medicine
32826416 The role and clinical significance of long noncoding RNA zinc finger E-box-binding homeobox two antisense RNA 1 in promoting osteosarcoma cancer cell proliferation, inhibiting apoptosis and increasing migration by regulating miR-145. Yinchuan Zhou 2021-02-01 Anti-cancer drugs
37564197 Lnc-ZEB2-19 Inhibits the Progression and Lenvatinib Resistance of Hepatocellular Carcinoma by Attenuating the NF-κB Signaling Pathway through the TRA2A/RSPH14 Axis. Mingbo Cao 2023-01-01 International journal of biological sciences
31564916 Long noncoding RNA ZEB2-AS1 facilitates laryngeal squamous cell carcinoma progression by miR-6840-3p/PLXNB1 axis. Qiushi Xu 2019-01-01 OncoTargets and therapy

Transcripts

Name Transcript ID bp Protein Translation ID
ZEB2-246 ENST00000639389 1414 70aa ENSP00000492572
ZEB2-244 ENST00000638087 9339 1102aa ENSP00000490673
ZEB2-243 ENST00000638007 9140 1102aa ENSP00000490723
ZEB2-233 ENST00000636413 8984 1102aa ENSP00000490508
ZEB2-238 ENST00000637045 9091 1102aa ENSP00000490141
ZEB2-237 ENST00000636820 9115 No protein -
ZEB2-232 ENST00000636179 8984 No protein -
ZEB2-240 ENST00000637304 9158 1102aa ENSP00000490872
ZEB2-245 ENST00000638128 8932 955aa ENSP00000490934
ZEB2-226 ENST00000627532 9265 1214aa ENSP00000487174
ZEB2-235 ENST00000636471 9583 1239aa ENSP00000490317
ZEB2-205 ENST00000419938 1755 220aa ENSP00000394777
ZEB2-204 ENST00000409487 5361 1214aa ENSP00000386854
ZEB2-210 ENST00000440875 4939 955aa ENSP00000475553
ZEB2-236 ENST00000636732 5073 122aa ENSP00000490175
ZEB2-231 ENST00000636026 5172 1202aa ENSP00000490776
ZEB2-247 ENST00000647488 1654 79aa ENSP00000494820
ZEB2-248 ENST00000675069 2203 391aa ENSP00000502467
ZEB2-250 ENST00000689298 4090 35aa ENSP00000508434
ZEB2-223 ENST00000539609 4061 1190aa ENSP00000443792
ZEB2-224 ENST00000558170 4012 1214aa ENSP00000454157
ZEB2-201 ENST00000303660 3913 1213aa ENSP00000302501
ZEB2-242 ENST00000637873 100 21aa ENSP00000489701
ZEB2-249 ENST00000675145 3014 No protein -
ZEB2-206 ENST00000427902 2236 731aa ENSP00000395496
ZEB2-239 ENST00000637267 2677 612aa ENSP00000490293
ZEB2-202 ENST00000392861 1514 467aa ENSP00000376601
ZEB2-222 ENST00000497268 674 No protein -
ZEB2-207 ENST00000431672 709 184aa ENSP00000475267
ZEB2-203 ENST00000409211 587 120aa ENSP00000387256
ZEB2-216 ENST00000465308 1071 141aa ENSP00000487476
ZEB2-208 ENST00000434448 583 41aa ENSP00000487261
ZEB2-218 ENST00000472146 3837 No protein -
ZEB2-213 ENST00000461784 751 No protein -
ZEB2-219 ENST00000476394 601 No protein -
ZEB2-241 ENST00000637591 480 No protein -
ZEB2-220 ENST00000479735 543 No protein -
ZEB2-209 ENST00000435831 554 91aa ENSP00000400993
ZEB2-212 ENST00000453352 581 No protein -
ZEB2-211 ENST00000444559 577 63aa ENSP00000399451
ZEB2-230 ENST00000630572 468 39aa ENSP00000486346
ZEB2-227 ENST00000628473 2967 No protein -
ZEB2-221 ENST00000484313 845 41aa ENSP00000486341
ZEB2-229 ENST00000629955 1435 No protein -
ZEB2-215 ENST00000465070 2949 58aa ENSP00000475502
ZEB2-217 ENST00000470879 2648 87aa ENSP00000475329
ZEB2-228 ENST00000629520 2564 58aa ENSP00000486240
ZEB2-234 ENST00000636445 2947 36aa ENSP00000490851
ZEB2-225 ENST00000625161 3061 No protein -
ZEB2-214 ENST00000462355 656 58aa ENSP00000475400

Gene Model

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID
81289Myopia, Degenerative6E-1023933737
89035Carcinoma, Renal Cell2E-823184150
93485Schizophrenia1E-823974872
93800Schizophrenia4E-726198764
105159Carcinoma, Renal Cell2E-725826619

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000169554homo_sapiensENSP0000041596158.577845.3333homo_sapiensENSP0000048717454.283442.0099

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000169554homo_sapiensENSP0000048717499.752999.6705nomascus_leucogenysENSNLEP0000003559796.64896.5682
ENSG00000169554homo_sapiensENSP0000048717499.917699.9176pan_paniscusENSPPAP0000000691996.807796.8077
ENSG00000169554homo_sapiensENSP0000048717499.752999.7529pongo_abeliiENSPPYP0000001432397.740197.7401
ENSG00000169554homo_sapiensENSP0000048717499.917699.9176pan_troglodytesENSPTRP0000009341396.807796.8077
ENSG00000169554homo_sapiensENSP0000048717499.835399.6705gorilla_gorillaENSGGOP0000004145396.805196.6454
ENSG00000169554homo_sapiensENSP0000048717493.57590.1153ornithorhynchus_anatinusENSOANP0000003995190.087286.7565
ENSG00000169554homo_sapiensENSP0000048717496.787594.6458sarcophilus_harrisiiENSSHAP0000003762295.68493.5668
ENSG00000169554homo_sapiensENSP0000048717466.14564.7446notamacropus_eugeniiENSMEUP0000000822080.380478.6787
ENSG00000169554homo_sapiensENSP0000048717492.668991.9275choloepus_hoffmanniENSCHOP0000000127294.936794.1772
ENSG00000169554homo_sapiensENSP0000048717499.093998.1878dasypus_novemcinctusENSDNOP0000003257196.859995.9742
ENSG00000169554homo_sapiensENSP0000048717471.828770.9226erinaceus_europaeusENSEEUP0000000525173.338972.4138
ENSG00000169554homo_sapiensENSP0000048717474.54772.8995echinops_telfairiENSETEP0000000269276.371374.6835
ENSG00000169554homo_sapiensENSP0000048717499.588199.5058callithrix_jacchusENSCJAP0000006138095.952495.873
ENSG00000169554homo_sapiensENSP0000048717499.835399.7529cercocebus_atysENSCATP0000003088396.727996.648
ENSG00000169554homo_sapiensENSP0000048717499.835399.7529macaca_fascicularisENSMFAP0000001513197.820897.7401
ENSG00000169554homo_sapiensENSP0000048717499.752999.6705macaca_mulattaENSMMUP0000004860899.835199.7527
ENSG00000169554homo_sapiensENSP0000048717499.835399.6705macaca_nemestrinaENSMNEP0000003217896.727996.5682
ENSG00000169554homo_sapiensENSP0000048717499.835399.7529papio_anubisENSPANP0000002386197.820897.7401
ENSG00000169554homo_sapiensENSP0000048717497.858397.7759mandrillus_leucophaeusENSMLEP0000000120897.058896.9771
ENSG00000169554homo_sapiensENSP0000048717498.764498.2702tursiops_truncatusENSTTRP0000000612798.683198.1893
ENSG00000169554homo_sapiensENSP0000048717498.187896.6227vulpes_vulpesENSVVUP0000001480498.187896.6227
ENSG00000169554homo_sapiensENSP0000048717498.352696.6227mus_spretusMGP_SPRETEiJ_P005370094.837293.1692
ENSG00000169554homo_sapiensENSP0000048717497.034696.5404equus_asinusENSEASP0000506113598.991698.4874
ENSG00000169554homo_sapiensENSP0000048717499.011598.4349capra_hircusENSCHIP0000002337099.011598.4349
ENSG00000169554homo_sapiensENSP0000048717499.093998.3526loxodonta_africanaENSLAFP0000000752299.093998.3526
ENSG00000169554homo_sapiensENSP0000048717498.929298.1878panthera_leoENSPLOP0000000653596.93396.2066
ENSG00000169554homo_sapiensENSP0000048717497.528896.5404ailuropoda_melanoleucaENSAMEP0000003248496.103995.1299
ENSG00000169554homo_sapiensENSP0000048717499.093998.4349bos_indicus_hybridENSBIXP0000503554796.78296.1384
ENSG00000169554homo_sapiensENSP0000048717497.199396.458oryctolagus_cuniculusENSOCUP0000001554199.326698.569
ENSG00000169554homo_sapiensENSP0000048717499.011598.5173equus_caballusENSECAP0000006183491.825891.3675
ENSG00000169554homo_sapiensENSP0000048717498.187896.7051canis_lupus_familiarisENSCAFP0084500851196.206694.7538
ENSG00000169554homo_sapiensENSP0000048717499.011598.2702panthera_pardusENSPPRP0000000161099.011598.2702
ENSG00000169554homo_sapiensENSP0000048717497.446596.9522marmota_marmota_marmotaENSMMMP0000002462999.495498.9907
ENSG00000169554homo_sapiensENSP0000048717417.627717.4629balaenoptera_musculusENSBMSP0001000279297.272796.3636
ENSG00000169554homo_sapiensENSP0000048717425.041224.9588balaenoptera_musculusENSBMSP0001000281899.672199.3443
ENSG00000169554homo_sapiensENSP0000048717499.505898.1878cavia_porcellusENSCPOP0000000377196.408695.1317
ENSG00000169554homo_sapiensENSP0000048717499.011598.2702felis_catusENSFCAP0000001440598.767598.0279
ENSG00000169554homo_sapiensENSP0000048717499.258798.3526ursus_americanusENSUAMP0000003534799.258798.3526
ENSG00000169554homo_sapiensENSP0000048717496.787594.9753monodelphis_domesticaENSMODP0000005661795.68493.8925
ENSG00000169554homo_sapiensENSP0000048717488.797486.5733bison_bison_bisonENSBBBP0000001901689.683987.4376
ENSG00000169554homo_sapiensENSP0000048717498.764498.1878monodon_monocerosENSMMNP0001500711396.693696.129
ENSG00000169554homo_sapiensENSP0000048717439.209239.1269sus_scrofaENSSSCP0000005299799.373799.1649
ENSG00000169554homo_sapiensENSP0000048717499.505899.0939microcebus_murinusENSMICP0000001804296.025495.628
ENSG00000169554homo_sapiensENSP0000048717499.423498.2702octodon_degusENSODEP0000000924496.328895.2115
ENSG00000169554homo_sapiensENSP0000048717498.929297.6936jaculus_jaculusENSJJAP0000001198496.156994.956
ENSG00000169554homo_sapiensENSP0000048717499.011598.4349ovis_aries_rambouilletENSOARP0002003258888.382487.8676
ENSG00000169554homo_sapiensENSP0000048717490.197789.7035ursus_maritimusENSUMAP0000000841799.09598.552
ENSG00000169554homo_sapiensENSP0000048717493.657392.9984ochotona_princepsENSOPRP0000000568894.044793.383
ENSG00000169554homo_sapiensENSP0000048717498.764498.1878delphinapterus_leucasENSDLEP0000002462398.683198.107
ENSG00000169554homo_sapiensENSP0000048717490.609688.3031physeter_catodonENSPCTP0000500172092.204589.8575
ENSG00000169554homo_sapiensENSP0000048717498.270296.6227mus_caroliMGP_CAROLIEiJ_P005165194.757793.1692
ENSG00000169554homo_sapiensENSP0000048717498.352696.7051mus_musculusENSMUSP0000002822994.837293.2486
ENSG00000169554homo_sapiensENSP0000048717499.423498.682dipodomys_ordiiENSDORP0000001867996.637395.9167
ENSG00000169554homo_sapiensENSP0000048717499.258798.4349mustela_putorius_furoENSMPUP0000000359199.01498.1923
ENSG00000169554homo_sapiensENSP0000048717499.588199.5881aotus_nancymaaeENSANAP0000002351096.488496.4884
ENSG00000169554homo_sapiensENSP0000048717499.670599.5881saimiri_boliviensis_boliviensisENSSBOP0000001952196.568296.4884
ENSG00000169554homo_sapiensENSP0000048717485.749685.0082vicugna_pacosENSVPAP0000000196287.552686.7956
ENSG00000169554homo_sapiensENSP0000048717499.835399.7529chlorocebus_sabaeusENSCSAP0000001226699.589299.507
ENSG00000169554homo_sapiensENSP0000048717492.092391.3509tupaia_belangeriENSTBEP0000001212394.028693.2717
ENSG00000169554homo_sapiensENSP0000048717498.846897.3641mesocricetus_auratusENSMAUP0000001617498.846897.3641
ENSG00000169554homo_sapiensENSP0000048717498.764498.2702phocoena_sinusENSPSNP0000001410796.382695.9003
ENSG00000169554homo_sapiensENSP0000048717498.929298.1878camelus_dromedariusENSCDRP0000503117597.011396.2843
ENSG00000169554homo_sapiensENSP0000048717499.258798.2702carlito_syrichtaENSTSYP0000000865297.099196.1321
ENSG00000169554homo_sapiensENSP0000048717496.952296.2109panthera_tigris_altaicaENSPTIP0000001757294.99694.2696
ENSG00000169554homo_sapiensENSP0000048717498.599797.117rattus_norvegicusENSRNOP0000000635095.075593.6458
ENSG00000169554homo_sapiensENSP0000048717499.588199.0115prolemur_simusENSPSMP0000000405597.578797.0137
ENSG00000169554homo_sapiensENSP0000048717498.68297.3641microtus_ochrogasterENSMOCP0000001875398.68297.3641
ENSG00000169554homo_sapiensENSP0000048717476.359175.5354sorex_araneusENSSARP0000000624191.873190.8821
ENSG00000169554homo_sapiensENSP0000048717498.68297.3641peromyscus_maniculatus_bairdiiENSPEMP0000000306095.306394.0334
ENSG00000169554homo_sapiensENSP0000048717499.093998.5997bos_mutusENSBMUP0000003400299.093998.5997
ENSG00000169554homo_sapiensENSP0000048717498.434996.7051mus_spicilegusENSMSIP0000002410694.916693.2486
ENSG00000169554homo_sapiensENSP0000048717499.011597.5288cricetulus_griseus_chok1gshdENSCGRP0000100320795.548594.1176
ENSG00000169554homo_sapiensENSP0000048717478.500877.6771pteropus_vampyrusENSPVAP0000001466778.630477.8053
ENSG00000169554homo_sapiensENSP0000048717497.199395.8814myotis_lucifugusENSMLUP0000000183599.159797.8151
ENSG00000169554homo_sapiensENSP0000048717497.775996.1285vombatus_ursinusENSVURP0001000705697.454895.8128
ENSG00000169554homo_sapiensENSP0000048717499.258798.3526rhinolophus_ferrumequinumENSRFEP0001000772995.939595.0637
ENSG00000169554homo_sapiensENSP0000048717489.209286.8204neovison_visonENSNVIP0000000486690.099887.6872
ENSG00000169554homo_sapiensENSP0000048717490.197789.7858bos_taurusENSBTAP0000005364699.364898.9111
ENSG00000169554homo_sapiensENSP0000048717410.37899.55519bos_taurusENSBTAP0000007457491.970884.6715
ENSG00000169554homo_sapiensENSP0000048717499.093998.1878heterocephalus_glaber_femaleENSHGLP0000002654197.172996.2843
ENSG00000169554homo_sapiensENSP0000048717497.858397.7759rhinopithecus_bietiENSRBIP0000001783097.058896.9771
ENSG00000169554homo_sapiensENSP0000048717491.186289.8682canis_lupus_dingoENSCAFP0002002060398.225496.8057
ENSG00000169554homo_sapiensENSP0000048717417.792417.5453sciurus_vulgarisENSSVLP0000500394898.181896.8182
ENSG00000169554homo_sapiensENSP0000048717497.858396.3756phascolarctos_cinereusENSPCIP0000001465397.536996.0591
ENSG00000169554homo_sapiensENSP0000048717495.634394.0692procavia_capensisENSPCAP0000001371198.640697.0263
ENSG00000169554homo_sapiensENSP0000048717499.011597.8583nannospalax_galiliENSNGAP0000001568899.011597.8583
ENSG00000169554homo_sapiensENSP0000048717490.93988.715bos_grunniensENSBGRP0000000765082.572980.5535
ENSG00000169554homo_sapiensENSP0000048717497.364196.458chinchilla_lanigeraENSCLAP0000000311598.582297.6647
ENSG00000169554homo_sapiensENSP0000048717499.011598.2702cervus_hanglu_yarkandensisENSCHYP0000001506396.701595.9775
ENSG00000169554homo_sapiensENSP0000048717490.93988.3855catagonus_wagneriENSCWAP0000002439192.695290.0924
ENSG00000169554homo_sapiensENSP0000048717499.423498.8468ictidomys_tridecemlineatusENSSTOP0000002751996.637396.0769
ENSG00000169554homo_sapiensENSP0000048717499.011598.0231otolemur_garnettiiENSOGAP0000000895199.256898.2659
ENSG00000169554homo_sapiensENSP0000048717499.588199.4234cebus_imitatorENSCCAP0000003800296.488496.3288
ENSG00000169554homo_sapiensENSP0000048717499.34198.8468urocitellus_parryiiENSUPAP0001000589995.866595.3895
ENSG00000169554homo_sapiensENSP0000048717499.093998.4349moschus_moschiferusENSMMSP0000002575096.859996.2158
ENSG00000169554homo_sapiensENSP0000048717499.835399.7529rhinopithecus_roxellanaENSRROP0000002622796.727996.648
ENSG00000169554homo_sapiensENSP0000048717498.434996.7051mus_pahariMGP_PahariEiJ_P006265394.916693.2486
ENSG00000169554homo_sapiensENSP0000048717499.670599.2587propithecus_coquereliENSPCOP0000002081796.184495.787
ENSG00000169554homo_sapiensENSP0000048717440.856731.1367petromyzon_marinusENSPMAP0000000405457.607443.9024
ENSG00000169554homo_sapiensENSP0000048717456.42542.257eptatretus_burgeriENSEBUP0000000171348.002835.9495
ENSG00000169554homo_sapiensENSP0000048717487.232378.2537callorhinchus_miliiENSCMIP0000002338386.945877.9967
ENSG00000169554homo_sapiensENSP0000048717492.91686.7381latimeria_chalumnaeENSLACP0000001130690.167984.1727
ENSG00000169554homo_sapiensENSP0000048717489.456381.1367lepisosteus_oculatusENSLOCP0000000147687.580679.4355
ENSG00000169554homo_sapiensENSP0000048717486.985276.6063clupea_harengusENSCHAP0000002611284.412574.3405
ENSG00000169554homo_sapiensENSP0000048717484.678771.911danio_rerioENSDARP0000008445284.331471.6161
ENSG00000169554homo_sapiensENSP0000048717484.596472.8995carassius_auratusENSCARP0000006692481.378870.1268
ENSG00000169554homo_sapiensENSP0000048717484.184572.7348carassius_auratusENSCARP0000008702979.843868.9844
ENSG00000169554homo_sapiensENSP0000048717487.232376.3591astyanax_mexicanusENSAMXP0000000824086.237875.4886
ENSG00000169554homo_sapiensENSP0000048717485.83274.547ictalurus_punctatusENSIPUP0000002602485.479974.2412
ENSG00000169554homo_sapiensENSP0000048717486.243876.112esox_luciusENSELUP0000005568081.288871.7391
ENSG00000169554homo_sapiensENSP0000048717485.914374.4646electrophorus_electricusENSEEEP0000005256084.727973.4362
ENSG00000169554homo_sapiensENSP0000048717486.985276.6063oncorhynchus_kisutchENSOKIP0000502774583.215173.286
ENSG00000169554homo_sapiensENSP0000048717486.902876.3591oncorhynchus_kisutchENSOKIP0000507891882.875172.8201
ENSG00000169554homo_sapiensENSP0000048717486.820476.3591oncorhynchus_mykissENSOMYP0000005013981.515971.6937
ENSG00000169554homo_sapiensENSP0000048717487.149976.6886oncorhynchus_mykissENSOMYP0000000291684.101774.0064
ENSG00000169554homo_sapiensENSP0000048717486.985276.4415salmo_salarENSSSAP0000005086582.371372.3869
ENSG00000169554homo_sapiensENSP0000048717487.067576.6886salmo_salarENSSSAP0000002376181.495871.781
ENSG00000169554homo_sapiensENSP0000048717486.738176.3591salmo_truttaENSSTUP0000004818183.30773.3386
ENSG00000169554homo_sapiensENSP0000048717486.985276.771salmo_truttaENSSTUP0000008551983.809573.9683
ENSG00000169554homo_sapiensENSP0000048717480.395468.6161gadus_morhuaENSGMOP0000001538579.738668.0556
ENSG00000169554homo_sapiensENSP0000048717483.443272.4053fundulus_heteroclitusENSFHEP0000001894684.628273.4336
ENSG00000169554homo_sapiensENSP0000048717452.800743.9044poecilia_reticulataENSPREP0000000656578.361965.1589
ENSG00000169554homo_sapiensENSP0000048717426.606322.4876poecilia_reticulataENSPREP0000003252077.45865.4676
ENSG00000169554homo_sapiensENSP0000048717483.690372.1582xiphophorus_maculatusENSXMAP0000001061078.516267.6971
ENSG00000169554homo_sapiensENSP0000048717483.525573.0642oryzias_latipesENSORLP0000000012084.995874.3504
ENSG00000169554homo_sapiensENSP0000048717480.560170.9226cyclopterus_lumpusENSCLMP0000502156176.227667.1083
ENSG00000169554homo_sapiensENSP0000048717485.996774.6293oreochromis_niloticusENSONIP0000001545583.187272.1912
ENSG00000169554homo_sapiensENSP0000048717484.102172.57haplochromis_burtoniENSHBUP0000000780185.439373.7238
ENSG00000169554homo_sapiensENSP0000048717486.161574.7941astatotilapia_callipteraENSACLP0000002144679.604369.102
ENSG00000169554homo_sapiensENSP0000048717485.667274.9588sparus_aurataENSSAUP0001004061984.89874.2857
ENSG00000169554homo_sapiensENSP0000048717484.184573.229lates_calcariferENSLCAP0001002923085.308874.207
ENSG00000169554homo_sapiensENSP0000048717493.080786.9028xenopus_tropicalisENSXETP0000007639188.836582.9403
ENSG00000169554homo_sapiensENSP0000048717496.787594.5634chrysemys_picta_belliiENSCPBP0000000073696.787594.5634
ENSG00000169554homo_sapiensENSP0000048717496.293293.1631sphenodon_punctatusENSSPUP0000001029293.820290.7705
ENSG00000169554homo_sapiensENSP000004871744.695224.28336sphenodon_punctatusENSSPUP0000001039174.02667.5325
ENSG00000169554homo_sapiensENSP0000048717495.387292.916crocodylus_porosusENSCPRP0000501064496.339493.8436
ENSG00000169554homo_sapiensENSP0000048717418.36917.3806laticauda_laticaudataENSLLTP0000002082789.919485.0806
ENSG00000169554homo_sapiensENSP0000048717473.970370.346laticauda_laticaudataENSLLTP0000000298693.153588.5892
ENSG00000169554homo_sapiensENSP0000048717495.469592.0099notechis_scutatusENSNSUP0000001392193.846290.4453
ENSG00000169554homo_sapiensENSP0000048717495.551992.0099pseudonaja_textilisENSPTXP0000001825192.948789.5032
ENSG00000169554homo_sapiensENSP0000048717496.705194.3987anas_platyrhynchos_platyrhynchosENSAPLP0000003158496.625594.321
ENSG00000169554homo_sapiensENSP0000048717487.726584.6787gallus_gallusENSGALP0001001303693.7590.493
ENSG00000169554homo_sapiensENSP000004871747.413516.2603meleagris_gallopavoENSMGAP0000002328276.271264.4068
ENSG00000169554homo_sapiensENSP0000048717490.197788.3031serinus_canariaENSSCAP0000001101197.160695.1198
ENSG00000169554homo_sapiensENSP0000048717496.293294.1516parus_majorENSPMJP0000002746196.293294.1516
ENSG00000169554homo_sapiensENSP0000048717494.563490.6096anolis_carolinensisENSACAP0000002165490.180786.4101
ENSG00000169554homo_sapiensENSP0000048717486.161574.7117neolamprologus_brichardiENSNBRP0000001943185.667574.2834
ENSG00000169554homo_sapiensENSP0000048717494.069290.2801naja_najaENSNNAP0000001985193.376989.6157
ENSG00000169554homo_sapiensENSP0000048717496.210992.4217podarcis_muralisENSPMRP0000001117296.052692.2697
ENSG00000169554homo_sapiensENSP0000048717495.716693.2455geospiza_fortisENSGFOP0000000001594.934692.4837
ENSG00000169554homo_sapiensENSP0000048717495.551992.9984taeniopygia_guttataENSTGUP0000001227094.771292.2386
ENSG00000169554homo_sapiensENSP0000048717489.126981.631erpetoichthys_calabaricusENSECRP0000001514789.643782.1044
ENSG00000169554homo_sapiensENSP0000048717483.607972.2405kryptolebias_marmoratusENSKMAP0000000543184.937273.3891
ENSG00000169554homo_sapiensENSP0000048717493.822190.033salvator_merianaeENSSMRP0000003063694.837691.0075
ENSG00000169554homo_sapiensENSP0000048717482.537172.2405oryzias_javanicusENSOJAP0000000059776.139866.6413
ENSG00000169554homo_sapiensENSP0000048717486.079175.0412amphilophus_citrinellusENSACIP0000001403183.868473.114
ENSG00000169554homo_sapiensENSP0000048717486.326275.7825dicentrarchus_labraxENSDLAP0000501687984.995974.6148
ENSG00000169554homo_sapiensENSP0000048717486.326275.3707amphiprion_perculaENSAPEP0000002961185.55174.6939
ENSG00000169554homo_sapiensENSP0000048717484.019872.57oryzias_sinensisENSOSIP0000002952583.675172.2724
ENSG00000169554homo_sapiensENSP0000048717496.869994.3163pelodiscus_sinensisENSPSIP0000001893295.609893.0894
ENSG00000169554homo_sapiensENSP0000048717496.869994.4811gopherus_evgoodeiENSGEVP0000503004496.869994.4811
ENSG00000169554homo_sapiensENSP0000048717496.540494.3987chelonoidis_abingdoniiENSCABP0000001569196.540494.3987
ENSG00000169554homo_sapiensENSP0000048717486.573375.5354seriola_dumeriliENSSDUP0000001820285.936274.9796
ENSG00000169554homo_sapiensENSP0000048717485.090674.2998cottoperca_gobioENSCGOP0000000581384.672173.9344
ENSG00000169554homo_sapiensENSP0000048717497.034694.8105struthio_camelus_australisENSSCUP0000001903596.954794.7325
ENSG00000169554homo_sapiensENSP0000048717495.057792.6689anser_brachyrhynchusENSABRP0000000920594.745592.3645
ENSG00000169554homo_sapiensENSP0000048717474.54765.6507gasterosteus_aculeatusENSGACP0000002065583.487173.524
ENSG00000169554homo_sapiensENSP0000048717479.736469.1104cynoglossus_semilaevisENSCSEP0000001083383.520372.39
ENSG00000169554homo_sapiensENSP0000048717486.161574.8764poecilia_formosaENSPFOP0000000475685.457574.2647
ENSG00000169554homo_sapiensENSP0000048717486.738176.1944myripristis_murdjanENSMMDP0000504921685.401575.0203
ENSG00000169554homo_sapiensENSP0000048717485.83275.453sander_luciopercaENSSLUP0000005844385.270174.9591
ENSG00000169554homo_sapiensENSP0000048717496.869994.5634strigops_habroptilaENSSHBP0000502112396.949794.6414
ENSG00000169554homo_sapiensENSP0000048717485.914375.0412amphiprion_ocellarisENSAOCP0000000551585.77374.9178
ENSG00000169554homo_sapiensENSP0000048717496.869994.6458terrapene_carolina_triunguisENSTMTP0000001856696.869994.6458
ENSG00000169554homo_sapiensENSP0000048717485.090674.9588hucho_huchoENSHHUP0000007440083.57673.6246
ENSG00000169554homo_sapiensENSP0000048717486.985276.9358hucho_huchoENSHHUP0000007359083.544373.8924
ENSG00000169554homo_sapiensENSP0000048717485.996774.8764betta_splendensENSBSLP0000001058185.294174.2647
ENSG00000169554homo_sapiensENSP0000048717486.820475.7002pygocentrus_nattereriENSPNAP0000003450585.691174.7154
ENSG00000169554homo_sapiensENSP0000048717485.996774.9588anabas_testudineusENSATEP0000001906381.946671.4286
ENSG00000169554homo_sapiensENSP0000048717484.431673.3114seriola_lalandi_dorsalisENSSLDP0000001339585.630774.3525
ENSG00000169554homo_sapiensENSP0000048717483.278472.6524labrus_bergyltaENSLBEP0000000602384.531873.7458
ENSG00000169554homo_sapiensENSP0000048717486.161574.7117pundamilia_nyerereiENSPNYP0000002949285.667574.2834
ENSG00000169554homo_sapiensENSP0000048717486.326275.453mastacembelus_armatusENSMAMP0000003343085.064974.3506
ENSG00000169554homo_sapiensENSP0000048717486.573375.7825stegastes_partitusENSSPAP0000002186585.86675.1634
ENSG00000169554homo_sapiensENSP0000048717475.370766.804oncorhynchus_tshawytschaENSOTSP0000506253684.879475.2319
ENSG00000169554homo_sapiensENSP0000048717486.985276.4415oncorhynchus_tshawytschaENSOTSP0000505094481.670571.7711
ENSG00000169554homo_sapiensENSP0000048717486.985276.4415oncorhynchus_tshawytschaENSOTSP0000509355281.987672.0497
ENSG00000169554homo_sapiensENSP0000048717486.490975.453acanthochromis_polyacanthusENSAPOP0000001345685.854574.8978
ENSG00000169554homo_sapiensENSP0000048717495.79993.1631aquila_chrysaetos_chrysaetosENSACCP0002000675295.016392.402
ENSG00000169554homo_sapiensENSP0000048717485.83274.547nothobranchius_furzeriENSNFUP0001502304483.3672.4
ENSG00000169554homo_sapiensENSP0000048717485.83274.6293cyprinodon_variegatusENSCVAP0000001944885.200374.0801
ENSG00000169554homo_sapiensENSP0000048717487.149976.6886denticeps_clupeoidesENSDCDP0000000049184.911774.7191
ENSG00000169554homo_sapiensENSP0000048717486.079175.453larimichthys_croceaENSLCRP0000505366085.445674.8978
ENSG00000169554homo_sapiensENSP0000048717485.996774.547takifugu_rubripesENSTRUP0000008755483.990372.8077
ENSG00000169554homo_sapiensENSP0000048717495.551992.9984ficedula_albicollisENSFALP0000001445094.771292.2386
ENSG00000169554homo_sapiensENSP0000048717484.761172.8995hippocampus_comesENSHCOP0000001217984.971173.0801
ENSG00000169554homo_sapiensENSP0000048717484.761173.229cyprinus_carpio_carpioENSCCRP0000003669581.151470.1104
ENSG00000169554homo_sapiensENSP0000048717485.008273.4761cyprinus_carpio_carpioENSCCRP0000010605384.382772.9354
ENSG00000169554homo_sapiensENSP0000048717492.092389.6211coturnix_japonicaENSCJPP0000502672495.392592.8328
ENSG00000169554homo_sapiensENSP0000048717484.019872.7348poecilia_latipinnaENSPLAP0000000984385.141973.7062
ENSG00000169554homo_sapiensENSP000004871747.660636.17792poecilia_latipinnaENSPLAP0000001517680.172464.6552
ENSG00000169554homo_sapiensENSP0000048717484.184572.3229sinocyclocheilus_grahamiENSSGRP0000008934983.770571.9672
ENSG00000169554homo_sapiensENSP0000048717484.596472.8171sinocyclocheilus_grahamiENSSGRP0000008703283.836772.1633
ENSG00000169554homo_sapiensENSP0000048717486.161574.7941maylandia_zebraENSMZEP0000502112785.667574.3653
ENSG00000169554homo_sapiensENSP0000048717484.678772.9819tetraodon_nigroviridisENSTNIP0000002030683.918472.3265
ENSG00000169554homo_sapiensENSP0000048717483.937472.9819paramormyrops_kingsleyaeENSPKIP0000001763485.630274.4538
ENSG00000169554homo_sapiensENSP0000048717486.161575.2883paramormyrops_kingsleyaeENSPKIP0000003140686.090575.2263
ENSG00000169554homo_sapiensENSP0000048717485.17374.9588scleropages_formosusENSSFOP0001503008186.817876.4064
ENSG00000169554homo_sapiensENSP0000048717488.385578.5008scleropages_formosusENSSFOP0001501010684.688275.217
ENSG00000169554homo_sapiensENSP0000048717491.762884.1845leptobrachium_leishanenseENSLLEP0000001433889.549882.1543
ENSG00000169554homo_sapiensENSP0000048717485.420174.6293scophthalmus_maximusENSSMAP0000000437379.892169.7997
ENSG00000169554homo_sapiensENSP0000048717485.008274.2998oryzias_melastigmaENSOMEP0000001875984.798774.1167

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0000122involved_in negative regulation of transcription by RNA polymerase II2IDA,IMPHomo_sapiens(9606)Process
GO:0000785part_of chromatin2IDA,ISAHomo_sapiens(9606)Component
GO:0000978enables RNA polymerase II cis-regulatory region sequence-specific DNA binding2IBA,IDAHomo_sapiens(9606)Function
GO:0000981enables DNA-binding transcription factor activity, RNA polymerase II-specific2IBA,ISAHomo_sapiens(9606)Function
GO:0001227enables DNA-binding transcription repressor activity, RNA polymerase II-specific1IDAHomo_sapiens(9606)Function
GO:0001935involved_in endothelial cell proliferation1IEAHomo_sapiens(9606)Process
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005634located_in nucleus1IDAHomo_sapiens(9606)Component
GO:0005654located_in nucleoplasm1IDAHomo_sapiens(9606)Component
GO:0005730located_in nucleolus1IDAHomo_sapiens(9606)Component
GO:0005829located_in cytosol1IDAHomo_sapiens(9606)Component
GO:0006357involved_in regulation of transcription by RNA polymerase II1IBAHomo_sapiens(9606)Process
GO:0007399involved_in nervous system development1NASHomo_sapiens(9606)Process
GO:0010764involved_in negative regulation of fibroblast migration1IEAHomo_sapiens(9606)Process
GO:0019208enables phosphatase regulator activity1NASHomo_sapiens(9606)Function
GO:0030511involved_in positive regulation of transforming growth factor beta receptor signaling pathway1IMPHomo_sapiens(9606)Process
GO:0036446involved_in myofibroblast differentiation1IEAHomo_sapiens(9606)Process
GO:0043149involved_in stress fiber assembly1IEAHomo_sapiens(9606)Process
GO:0043542involved_in endothelial cell migration1IEAHomo_sapiens(9606)Process
GO:0044271involved_in cellular nitrogen compound biosynthetic process1IEAHomo_sapiens(9606)Process
GO:0045636involved_in positive regulation of melanocyte differentiation1ISSHomo_sapiens(9606)Process
GO:0045944involved_in positive regulation of transcription by RNA polymerase II1IMPHomo_sapiens(9606)Process
GO:0046872enables metal ion binding1IEAHomo_sapiens(9606)Function
GO:0048023involved_in positive regulation of melanin biosynthetic process1ICHomo_sapiens(9606)Process
GO:0048066involved_in developmental pigmentation1ISSHomo_sapiens(9606)Process
GO:0048143involved_in astrocyte activation1IEAHomo_sapiens(9606)Process
GO:0048856involved_in anatomical structure development1IBAHomo_sapiens(9606)Process
GO:0070269involved_in pyroptosis1IEAHomo_sapiens(9606)Process
GO:0072537involved_in fibroblast activation1IEAHomo_sapiens(9606)Process
GO:0090263involved_in positive regulation of canonical Wnt signaling pathway1IMPHomo_sapiens(9606)Process
GO:0090649involved_in response to oxygen-glucose deprivation1IEAHomo_sapiens(9606)Process
GO:0097324involved_in melanocyte migration1ISSHomo_sapiens(9606)Process
GO:1903056involved_in regulation of melanosome organization1ISSHomo_sapiens(9606)Process
GO:1904330involved_in positive regulation of myofibroblast contraction1IEAHomo_sapiens(9606)Process
GO:1904520involved_in regulation of myofibroblast cell apoptotic process1IEAHomo_sapiens(9606)Process
GO:1905603involved_in regulation of blood-brain barrier permeability1IEAHomo_sapiens(9606)Process

Expression