RBPWorld - a comprehensive database of RNA Binding Proteins

Functions and Diseases

RBP Type	Canonical_RBPs
Diseases	N.A.
Drug	N.A.
Main interacting RNAs	diverse
Moonlighting functions	Transmemebrane
Localizations	N.A.
BulkPerturb-seq	N.A.

Description

Ensembl ID	ENSG00000169413	Gene ID	6039	Accession	10048
Symbol	RNASE6	Alias	RAD1;RNS6;RNasek6	Full Name	ribonuclease A family member k6
Status	Confidence	Length	1200 bases	Strand	Plus strand
Position	14 : 20781268 - 20782467	RNA binding domain	RnaseA
Summary	The protein encoded by this gene is a member of the ribonuclease A superfamily and functions in the urinary tract. The protein has broad-spectrum antimicrobial activity against pathogenic bacteria. [provided by RefSeq, Nov 2014]

RNA binding domains (RBDs)

Search:

Protein	Domain	Pfam ID	E-value	Domain number
ENSP00000302046	RnaseA	PF00074	2.7e-40	1

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RNA binding proteomes (RBPomes)

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Pubmed ID	Full Name	Cell	Author	Time	Doi
22658674	RIC_PMID22658674_Hela_human	Hela	Alfredo Castello	2012 Jun 8	doi: 10.1016/j.cell.2012.04.031.?Epub 2012 May 31
33735607	ChIRP.MS_PMID33735607_human		Bingfei Yu	2021 Apr 1	doi: 10.1016/j.cell.2021.02.015.?Epub 2021 Mar 17
37421941	RIC_PMID37421941_Hydra10_human		Wenhao Jin	2023 Jul 20	doi: 10.1016/j.molcel.2023.06.019.?Epub 2023 Jul 7

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Pubmed ID	Title	Author	Time	Journal
No data available in table

Transcripts

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Name	Transcript ID	bp	Protein	Translation ID
RNASE6-201	ENST00000304677	844	150aa	ENSP00000302046

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Gene Model

Click here to download ENSG00000169413's gene model file

Phenotypes

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ensgID	Trait	pValue	Pubmed ID
83666	Urine	8E-8	23251661

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ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID
No data available in table

Protein-Protein Interaction (PPI)

Click here to download ENSG00000169413's PPI file

Paralogs

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Search:

Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
ENSG00000169413	homo_sapiens	ENSP00000512867	31.2925	20.4082	homo_sapiens	ENSP00000302046	30.6667	20
ENSG00000169413	homo_sapiens	ENSP00000298690	62.8205	51.9231	homo_sapiens	ENSP00000302046	65.3333	54
ENSG00000169413	homo_sapiens	ENSP00000311398	62.987	52.5974	homo_sapiens	ENSP00000302046	64.6667	54
ENSG00000169413	homo_sapiens	ENSP00000392996	25.463	17.5926	homo_sapiens	ENSP00000302046	36.6667	25.3333
ENSG00000169413	homo_sapiens	ENSP00000451318	25.6281	15.0754	homo_sapiens	ENSP00000302046	34	20
ENSG00000169413	homo_sapiens	ENSP00000381077	38.0952	26.5306	homo_sapiens	ENSP00000302046	37.3333	26
ENSG00000169413	homo_sapiens	ENSP00000384683	25.7143	13.3333	homo_sapiens	ENSP00000302046	36	18.6667
ENSG00000169413	homo_sapiens	ENSP00000381057	46.7949	31.4103	homo_sapiens	ENSP00000302046	48.6667	32.6667
ENSG00000169413	homo_sapiens	ENSP00000452245	43.5374	32.6531	homo_sapiens	ENSP00000302046	42.6667	32
ENSG00000169413	homo_sapiens	ENSP00000372410	29.4872	17.9487	homo_sapiens	ENSP00000302046	30.6667	18.6667

Showing 1 to 10 of 12 entries

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Orthologs

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Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
ENSG00000169413	homo_sapiens	ENSP00000302046	96.6667	95.3333	nomascus_leucogenys	ENSNLEP00000009149	96.6667	95.3333
ENSG00000169413	homo_sapiens	ENSP00000302046	99.3333	98.6667	pan_paniscus	ENSPPAP00000020246	99.3333	98.6667
ENSG00000169413	homo_sapiens	ENSP00000302046	51.3333	50	pongo_abelii	ENSPPYP00000039107	87.5	85.2273
ENSG00000169413	homo_sapiens	ENSP00000302046	99.3333	99.3333	pan_troglodytes	ENSPTRP00000010358	99.3333	99.3333
ENSG00000169413	homo_sapiens	ENSP00000302046	98.6667	98.6667	gorilla_gorilla	ENSGGOP00000027666	98.6667	98.6667
ENSG00000169413	homo_sapiens	ENSP00000302046	81.3333	72	choloepus_hoffmanni	ENSCHOP00000010061	79.7386	70.5882
ENSG00000169413	homo_sapiens	ENSP00000302046	75.3333	62	erinaceus_europaeus	ENSEEUP00000011165	72.4359	59.6154
ENSG00000169413	homo_sapiens	ENSP00000302046	78	68	echinops_telfairi	ENSETEP00000009115	76.4706	66.6667
ENSG00000169413	homo_sapiens	ENSP00000302046	47.3333	41.3333	callithrix_jacchus	ENSCJAP00000073424	73.9583	64.5833
ENSG00000169413	homo_sapiens	ENSP00000302046	97.3333	94.6667	macaca_fascicularis	ENSMFAP00000010073	97.3333	94.6667

Showing 1 to 10 of 91 entries

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Gene Ontology

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Go ID	Go term	No. evidence	Entries	Species	Category
GO:0004540	enables RNA nuclease activity	2	IBA,IDA	Homo_sapiens(9606)	Function
GO:0005615	is_active_in extracellular space	2	IBA,IDA	Homo_sapiens(9606)	Component
GO:0019731	involved_in antibacterial humoral response	2	IBA,IDA	Homo_sapiens(9606)	Process
GO:0045087	involved_in innate immune response	2	IBA,IDA	Homo_sapiens(9606)	Process
GO:0050829	involved_in defense response to Gram-negative bacterium	2	IBA,IDA	Homo_sapiens(9606)	Process
GO:0050830	involved_in defense response to Gram-positive bacterium	2	IBA,IDA	Homo_sapiens(9606)	Process
GO:0051607	NOT involved_in defense response to virus	2	IDA	Homo_sapiens(9606)	Process
GO:0061844	involved_in antimicrobial humoral immune response mediated by antimicrobial peptide	2	IBA,IDA	Homo_sapiens(9606)	Process
GO:0003676	enables nucleic acid binding	1	IEA	Homo_sapiens(9606)	Function
GO:0004519	enables endonuclease activity	1	IEA	Homo_sapiens(9606)	Function

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Welcome to

RBP World!

Functions and Diseases

Description

RNA binding domains (RBDs)

RNA binding proteomes (RBPomes)

Literatures on RNA binding capacity

Transcripts

Gene Model

Pathways

Phenotypes

GWAS

Protein-Protein Interaction (PPI)

Paralogs

Orthologs

Gene Ontology

Expression