RBP Type
Canonical_RBPs
Diseases
N.A.
Drug
N.A.
Main interacting RNAs
diverse
Moonlighting functions
Transmemebrane
Localizations
N.A.
BulkPerturb-seq
N.A.
Ensembl ID ENSG00000169413 Gene ID
6039 Accession
10048
Symbol
RNASE6
Alias
RAD1;RNS6;RNasek6
Full Name
ribonuclease A family member k6
Status
Confidence
Length
1200 bases
Strand
Plus strand
Position
14 : 20781268 - 20782467
RNA binding domain
RnaseA
Summary
The protein encoded by this gene is a member of the ribonuclease A superfamily and functions in the urinary tract. The protein has broad-spectrum antimicrobial activity against pathogenic bacteria. [provided by RefSeq, Nov 2014]
RNA binding domains (RBDs)
Protein
Domain
Pfam ID
E-value
Domain number
ENSP00000302046
RnaseA
PF00074 2.7e-40
1
RNA binding proteomes (RBPomes)
Pubmed ID
Full Name
Cell
Author
Time
Doi
Literatures on RNA binding capacity
Pubmed ID
Title
Author
Time
Journal
Name
Transcript ID
bp
Protein
Translation ID
RNASE6-201
ENST00000304677
844
150aa
ENSP00000302046
Pathway ID
Pathway Name
Source
ensgID
Trait
pValue
Pubmed ID
83666 Urine 8E-8 23251661
ensgID SNP Chromosome Position
Trait PubmedID Or or BEAT
EFO ID
Protein-Protein Interaction (PPI)
Ensembl ID
Source
Target
Species
Protein ID
Perc_pos
Perc_id
Species
Protein ID
Perc_pos
Perc_id
ENSG00000169413 homo_sapiens ENSP00000512867 31.2925 20.4082 homo_sapiens ENSP00000302046 30.6667 20 ENSG00000169413 homo_sapiens ENSP00000298690 62.8205 51.9231 homo_sapiens ENSP00000302046 65.3333 54 ENSG00000169413 homo_sapiens ENSP00000311398 62.987 52.5974 homo_sapiens ENSP00000302046 64.6667 54 ENSG00000169413 homo_sapiens ENSP00000392996 25.463 17.5926 homo_sapiens ENSP00000302046 36.6667 25.3333 ENSG00000169413 homo_sapiens ENSP00000451318 25.6281 15.0754 homo_sapiens ENSP00000302046 34 20 ENSG00000169413 homo_sapiens ENSP00000381077 38.0952 26.5306 homo_sapiens ENSP00000302046 37.3333 26 ENSG00000169413 homo_sapiens ENSP00000384683 25.7143 13.3333 homo_sapiens ENSP00000302046 36 18.6667 ENSG00000169413 homo_sapiens ENSP00000381057 46.7949 31.4103 homo_sapiens ENSP00000302046 48.6667 32.6667 ENSG00000169413 homo_sapiens ENSP00000452245 43.5374 32.6531 homo_sapiens ENSP00000302046 42.6667 32 ENSG00000169413 homo_sapiens ENSP00000372410 29.4872 17.9487 homo_sapiens ENSP00000302046 30.6667 18.6667 ENSG00000169413 homo_sapiens ENSP00000302324 53.75 41.25 homo_sapiens ENSP00000302046 57.3333 44 ENSG00000169413 homo_sapiens ENSP00000303276 51.5528 41.6149 homo_sapiens ENSP00000302046 55.3333 44.6667
Ensembl ID
Source
Target
Species
Protein ID
Perc_pos
Perc_id
Species
Protein ID
Perc_pos
Perc_id
ENSG00000169413 homo_sapiens ENSP00000302046 96.6667 95.3333 nomascus_leucogenys ENSNLEP00000009149 96.6667 95.3333 ENSG00000169413 homo_sapiens ENSP00000302046 99.3333 98.6667 pan_paniscus ENSPPAP00000020246 99.3333 98.6667 ENSG00000169413 homo_sapiens ENSP00000302046 51.3333 50 pongo_abelii ENSPPYP00000039107 87.5 85.2273 ENSG00000169413 homo_sapiens ENSP00000302046 99.3333 99.3333 pan_troglodytes ENSPTRP00000010358 99.3333 99.3333 ENSG00000169413 homo_sapiens ENSP00000302046 98.6667 98.6667 gorilla_gorilla ENSGGOP00000027666 98.6667 98.6667 ENSG00000169413 homo_sapiens ENSP00000302046 81.3333 72 choloepus_hoffmanni ENSCHOP00000010061 79.7386 70.5882 ENSG00000169413 homo_sapiens ENSP00000302046 75.3333 62 erinaceus_europaeus ENSEEUP00000011165 72.4359 59.6154 ENSG00000169413 homo_sapiens ENSP00000302046 78 68 echinops_telfairi ENSETEP00000009115 76.4706 66.6667 ENSG00000169413 homo_sapiens ENSP00000302046 47.3333 41.3333 callithrix_jacchus ENSCJAP00000073424 73.9583 64.5833 ENSG00000169413 homo_sapiens ENSP00000302046 97.3333 94.6667 macaca_fascicularis ENSMFAP00000010073 97.3333 94.6667 ENSG00000169413 homo_sapiens ENSP00000302046 98 95.3333 macaca_mulatta ENSMMUP00000002223 98 95.3333 ENSG00000169413 homo_sapiens ENSP00000302046 98 95.3333 macaca_nemestrina ENSMNEP00000028998 98 95.3333 ENSG00000169413 homo_sapiens ENSP00000302046 82 76 tursiops_truncatus ENSTTRP00000010117 80.3922 74.5098 ENSG00000169413 homo_sapiens ENSP00000302046 57.3333 44.6667 vulpes_vulpes ENSVVUP00000012292 49.1429 38.2857 ENSG00000169413 homo_sapiens ENSP00000302046 58.6667 44 vulpes_vulpes ENSVVUP00000012281 30.9859 23.2394 ENSG00000169413 homo_sapiens ENSP00000302046 76.6667 65.3333 mus_spretus MGP_SPRETEiJ_P0038224 75.1634 64.0523 ENSG00000169413 homo_sapiens ENSP00000302046 82.6667 72 equus_asinus ENSEASP00005056300 80.5195 70.1299 ENSG00000169413 homo_sapiens ENSP00000302046 70 60.6667 capra_hircus ENSCHIP00000009541 76.087 65.942 ENSG00000169413 homo_sapiens ENSP00000302046 81.3333 69.3333 capra_hircus ENSCHIP00000001227 79.2208 67.5325 ENSG00000169413 homo_sapiens ENSP00000302046 78.6667 69.3333 loxodonta_africana ENSLAFP00000017312 76.6234 67.5325 ENSG00000169413 homo_sapiens ENSP00000302046 75.3333 62.6667 loxodonta_africana ENSLAFP00000025357 74.8344 62.2517 ENSG00000169413 homo_sapiens ENSP00000302046 80.6667 64 panthera_leo ENSPLOP00000011132 78.5714 62.3377 ENSG00000169413 homo_sapiens ENSP00000302046 60.6667 47.3333 ailuropoda_melanoleuca ENSAMEP00000030285 60.2649 47.0199 ENSG00000169413 homo_sapiens ENSP00000302046 58.6667 46.6667 ailuropoda_melanoleuca ENSAMEP00000020892 58.2781 46.3576 ENSG00000169413 homo_sapiens ENSP00000302046 54 39.3333 ailuropoda_melanoleuca ENSAMEP00000020735 53.6424 39.0728 ENSG00000169413 homo_sapiens ENSP00000302046 66 52.6667 ailuropoda_melanoleuca ENSAMEP00000016615 64.7059 51.634 ENSG00000169413 homo_sapiens ENSP00000302046 80 68.6667 bos_indicus_hybrid ENSBIXP00005037821 77.9221 66.8831 ENSG00000169413 homo_sapiens ENSP00000302046 83.3333 75.3333 oryctolagus_cuniculus ENSOCUP00000006480 81.1688 73.3766 ENSG00000169413 homo_sapiens ENSP00000302046 83.3333 72 equus_caballus ENSECAP00000081426 81.1688 70.1299 ENSG00000169413 homo_sapiens ENSP00000302046 28 22 canis_lupus_familiaris ENSCAFP00845032222 53.8462 42.3077 ENSG00000169413 homo_sapiens ENSP00000302046 35.3333 28 canis_lupus_familiaris ENSCAFP00845032300 63.8554 50.6024 ENSG00000169413 homo_sapiens ENSP00000302046 80.6667 64 panthera_pardus ENSPPRP00000028084 78.5714 62.3377 ENSG00000169413 homo_sapiens ENSP00000302046 86 74 marmota_marmota_marmota ENSMMMP00000016921 84.3137 72.549 ENSG00000169413 homo_sapiens ENSP00000302046 83.3333 76 balaenoptera_musculus ENSBMSP00010012173 81.1688 74.026 ENSG00000169413 homo_sapiens ENSP00000302046 65.3333 49.3333 cavia_porcellus ENSCPOP00000030314 52.4064 39.5722 ENSG00000169413 homo_sapiens ENSP00000302046 78 65.3333 cavia_porcellus ENSCPOP00000031670 77.4834 64.9007 ENSG00000169413 homo_sapiens ENSP00000302046 53.3333 40 cavia_porcellus ENSCPOP00000014763 52.9801 39.7351 ENSG00000169413 homo_sapiens ENSP00000302046 77.3333 61.3333 felis_catus ENSFCAP00000018950 75.3247 59.7403 ENSG00000169413 homo_sapiens ENSP00000302046 59.3333 46 ursus_americanus ENSUAMP00000004437 57.7922 44.8052 ENSG00000169413 homo_sapiens ENSP00000302046 54 44.6667 ursus_americanus ENSUAMP00000014034 68.6441 56.7797 ENSG00000169413 homo_sapiens ENSP00000302046 68 54 ursus_americanus ENSUAMP00000004543 67.5497 53.6424 ENSG00000169413 homo_sapiens ENSP00000302046 80 68.6667 bison_bison_bison ENSBBBP00000001794 77.9221 66.8831 ENSG00000169413 homo_sapiens ENSP00000302046 82.6667 76.6667 monodon_monoceros ENSMMNP00015013313 80.5195 74.6753 ENSG00000169413 homo_sapiens ENSP00000302046 80 70.6667 sus_scrofa ENSSSCP00000071780 78.4314 69.281 ENSG00000169413 homo_sapiens ENSP00000302046 79.3333 68.6667 ovis_aries_rambouillet ENSOARP00020017094 55.3488 47.907 ENSG00000169413 homo_sapiens ENSP00000302046 75.3333 64.6667 ovis_aries_rambouillet ENSOARP00020013926 72.9032 62.5806 ENSG00000169413 homo_sapiens ENSP00000302046 59.3333 46 ursus_maritimus ENSUMAP00000002644 53.2934 41.3174 ENSG00000169413 homo_sapiens ENSP00000302046 67.3333 53.3333 ursus_maritimus ENSUMAP00000002666 64.3312 50.9554 ENSG00000169413 homo_sapiens ENSP00000302046 76 65.3333 ochotona_princeps ENSOPRP00000002899 73.5484 63.2258 ENSG00000169413 homo_sapiens ENSP00000302046 74 68.6667 delphinapterus_leucas ENSDLEP00000002318 82.8358 76.8657 ENSG00000169413 homo_sapiens ENSP00000302046 83.3333 75.3333 physeter_catodon ENSPCTP00005004261 81.1688 73.3766 ENSG00000169413 homo_sapiens ENSP00000302046 74.6667 65.3333 mus_caroli MGP_CAROLIEiJ_P0036504 73.2026 64.0523 ENSG00000169413 homo_sapiens ENSP00000302046 75.3333 64 mus_musculus ENSMUSP00000154125 73.8562 62.7451 ENSG00000169413 homo_sapiens ENSP00000302046 68 58 mustela_putorius_furo ENSMPUP00000018266 67.5497 57.6159 ENSG00000169413 homo_sapiens ENSP00000302046 77.3333 65.3333 vicugna_pacos ENSVPAP00000010466 75.817 64.0523 ENSG00000169413 homo_sapiens ENSP00000302046 77.3333 65.3333 vicugna_pacos ENSVPAP00000006856 75.817 64.0523 ENSG00000169413 homo_sapiens ENSP00000302046 96.6667 94 chlorocebus_sabaeus ENSCSAP00000017653 96.6667 94 ENSG00000169413 homo_sapiens ENSP00000302046 73.3333 64 mesocricetus_auratus ENSMAUP00000003040 71.8954 62.7451 ENSG00000169413 homo_sapiens ENSP00000302046 80 63.3333 panthera_tigris_altaica ENSPTIP00000001581 77.9221 61.6883 ENSG00000169413 homo_sapiens ENSP00000302046 73.3333 62.6667 rattus_norvegicus ENSRNOP00000031392 71.8954 61.4379 ENSG00000169413 homo_sapiens ENSP00000302046 77.3333 64.6667 microtus_ochrogaster ENSMOCP00000000041 76.3158 63.8158 ENSG00000169413 homo_sapiens ENSP00000302046 78 66 sorex_araneus ENSSARP00000008626 75.974 64.2857 ENSG00000169413 homo_sapiens ENSP00000302046 76.6667 67.3333 peromyscus_maniculatus_bairdii ENSPEMP00000029539 72.7848 63.924 ENSG00000169413 homo_sapiens ENSP00000302046 79.3333 68 bos_mutus ENSBMUP00000015895 77.2727 66.2338 ENSG00000169413 homo_sapiens ENSP00000302046 76.6667 66.6667 cricetulus_griseus_chok1gshd ENSCGRP00001014154 75.1634 65.3595 ENSG00000169413 homo_sapiens ENSP00000302046 77.3333 67.3333 pteropus_vampyrus ENSPVAP00000012794 75.3247 65.5844 ENSG00000169413 homo_sapiens ENSP00000302046 69.3333 59.3333 myotis_lucifugus ENSMLUP00000011747 70.2703 60.1351 ENSG00000169413 homo_sapiens ENSP00000302046 76 66.6667 myotis_lucifugus ENSMLUP00000017518 69.9387 61.3497 ENSG00000169413 homo_sapiens ENSP00000302046 85.3333 74.6667 myotis_lucifugus ENSMLUP00000005037 83.1169 72.7273 ENSG00000169413 homo_sapiens ENSP00000302046 79.3333 71.3333 myotis_lucifugus ENSMLUP00000019251 81.5069 73.2877 ENSG00000169413 homo_sapiens ENSP00000302046 65.3333 58.6667 vombatus_ursinus ENSVURP00010026214 65.3333 58.6667 ENSG00000169413 homo_sapiens ENSP00000302046 85.3333 72 rhinolophus_ferrumequinum ENSRFEP00010025745 83.1169 70.1299 ENSG00000169413 homo_sapiens ENSP00000302046 68 58 neovison_vison ENSNVIP00000017037 64.557 55.0633 ENSG00000169413 homo_sapiens ENSP00000302046 61.3333 49.3333 neovison_vison ENSNVIP00000016998 63.4483 51.0345 ENSG00000169413 homo_sapiens ENSP00000302046 62 46 neovison_vison ENSNVIP00000016977 57.764 42.8571 ENSG00000169413 homo_sapiens ENSP00000302046 80 68.6667 bos_taurus ENSBTAP00000011585 77.9221 66.8831 ENSG00000169413 homo_sapiens ENSP00000302046 62.6667 51.3333 heterocephalus_glaber_female ENSHGLP00000040026 63.9456 52.381 ENSG00000169413 homo_sapiens ENSP00000302046 62.6667 50.6667 heterocephalus_glaber_female ENSHGLP00000050944 63.0872 51.0067 ENSG00000169413 homo_sapiens ENSP00000302046 76.6667 64.6667 heterocephalus_glaber_female ENSHGLP00000037986 76.1589 64.2384 ENSG00000169413 homo_sapiens ENSP00000302046 98 95.3333 rhinopithecus_bieti ENSRBIP00000002411 98 95.3333 ENSG00000169413 homo_sapiens ENSP00000302046 56.6667 44.6667 canis_lupus_dingo ENSCAFP00020018002 54.1401 42.6752 ENSG00000169413 homo_sapiens ENSP00000302046 88 76.6667 sciurus_vulgaris ENSSVLP00005002028 86.2745 75.1634 ENSG00000169413 homo_sapiens ENSP00000302046 58 43.3333 phascolarctos_cinereus ENSPCIP00000047320 51.1765 38.2353 ENSG00000169413 homo_sapiens ENSP00000302046 76.6667 62 procavia_capensis ENSPCAP00000011532 74.6753 60.3896 ENSG00000169413 homo_sapiens ENSP00000302046 84 72 nannospalax_galili ENSNGAP00000010125 83.4437 71.5232 ENSG00000169413 homo_sapiens ENSP00000302046 80 68 cervus_hanglu_yarkandensis ENSCHYP00000021344 77.9221 66.2338 ENSG00000169413 homo_sapiens ENSP00000302046 77.3333 66 catagonus_wagneri ENSCWAP00000008411 75.817 64.7059 ENSG00000169413 homo_sapiens ENSP00000302046 85.3333 72.6667 ictidomys_tridecemlineatus ENSSTOP00000011859 83.6601 71.2418 ENSG00000169413 homo_sapiens ENSP00000302046 83.3333 76.6667 otolemur_garnettii ENSOGAP00000006954 83.8926 77.1812 ENSG00000169413 homo_sapiens ENSP00000302046 85.3333 73.3333 urocitellus_parryii ENSUPAP00010002285 83.1169 71.4286 ENSG00000169413 homo_sapiens ENSP00000302046 75.3333 65.3333 mus_pahari MGP_PahariEiJ_P0084624 73.8562 64.0523
Go ID
Go term
No. evidence
Entries
Species
Category
GO:0003676 enables nucleic acid binding 1 IEA Homo_sapiens(9606) Function GO:0004519 enables endonuclease activity 1 IEA Homo_sapiens(9606) Function GO:0004540 enables RNA nuclease activity 2 IBA,IDA Homo_sapiens(9606) Function GO:0005576 located_in extracellular region 1 TAS Homo_sapiens(9606) Component GO:0005615 is_active_in extracellular space 2 IBA,IDA Homo_sapiens(9606) Component GO:0005764 located_in lysosome 1 IEA Homo_sapiens(9606) Component GO:0006401 involved_in RNA catabolic process 1 TAS Homo_sapiens(9606) Process GO:0006952 involved_in defense response 1 TAS Homo_sapiens(9606) Process GO:0019731 involved_in antibacterial humoral response 2 IBA,IDA Homo_sapiens(9606) Process GO:0031410 located_in cytoplasmic vesicle 1 IDA Homo_sapiens(9606) Component GO:0045087 involved_in innate immune response 2 IBA,IDA Homo_sapiens(9606) Process GO:0050829 involved_in defense response to Gram-negative bacterium 2 IBA,IDA Homo_sapiens(9606) Process GO:0050830 involved_in defense response to Gram-positive bacterium 2 IBA,IDA Homo_sapiens(9606) Process GO:0051607 NOT involved_in defense response to virus 2 IDA Homo_sapiens(9606) Process GO:0061844 involved_in antimicrobial humoral immune response mediated by antimicrobial peptide 2 IBA,IDA Homo_sapiens(9606) Process
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