RBP Type	Non-canonical_RBPs
Diseases	N.A.
Drug	N.A.
Main interacting RNAs	N.A.
Moonlighting functions	Metabolic enzyme
Localizations	N.A.
BulkPerturb-seq

Ensembl ID	ENSG00000168710	Gene ID	10768	Accession	344
Symbol	AHCYL1	Alias	DCAL;IRBIT;PPP1R78;PRO0233;XPVKONA	Full Name	adenosylhomocysteinase like 1
Status	Confidence	Length	38978 bases	Strand	Plus strand
Position	1 : 109984765 - 110023742	RNA binding domain	N.A.
Summary	The protein encoded by this gene interacts with inositol 1,4,5-trisphosphate receptor, type 1 and may be involved in the conversion of S-adenosyl-L-homocysteine to L-homocysteine and adenosine. Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jun 2011]

Protein	Domain	Pfam ID	E-value	Domain number

Pubmed ID	Full Name	Cell	Author	Time	Doi

Pubmed ID	Title	Author	Time	Journal
31281537	Survey of the translation shifts in hepatocellular carcinoma with ribosome profiling.	Qin Zou	2019-01-01	Theranostics

Name	Transcript ID	bp	Protein	Translation ID
AHCYL1-203	ENST00000393614	4313	483aa	ENSP00000377238
AHCYL1-202	ENST00000369799	3943	530aa	ENSP00000358814
AHCYL1-205	ENST00000475081	795	No protein	-
AHCYL1-201	ENST00000359172	2503	483aa	ENSP00000352092
AHCYL1-206	ENST00000481423	732	No protein	-
AHCYL1-204	ENST00000469401	575	No protein	-

Pathway ID	Pathway Name	Source

ensgID	Trait	pValue	Pubmed ID
6139	Hemoglobins	1.5844912674634E-5	17903294
6684	Platelet Aggregation	5.79810965349209E-6	17903294
86180	Alzheimer Disease	1E-6	26830138
86181	Age of Onset	1E-6	26830138

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0003723	enables RNA binding	1	IEA	Homo_sapiens(9606)	Function
GO:0004013	NOT enables adenosylhomocysteinase activity	1	IBA	Homo_sapiens(9606)	Function
GO:0005515	enables protein binding	1	IPI	Homo_sapiens(9606)	Function
GO:0005737	located_in cytoplasm	1	ISS	Homo_sapiens(9606)	Component
GO:0005789	located_in endoplasmic reticulum membrane	1	TAS	Homo_sapiens(9606)	Component
GO:0005829	is_active_in cytosol	1	IBA	Homo_sapiens(9606)	Component
GO:0006378	involved_in mRNA polyadenylation	1	IDA	Homo_sapiens(9606)	Process
GO:0006611	involved_in protein export from nucleus	1	IEA	Homo_sapiens(9606)	Process
GO:0006730	involved_in one-carbon metabolic process	1	IEA	Homo_sapiens(9606)	Process
GO:0006915	involved_in apoptotic process	1	IMP	Homo_sapiens(9606)	Process
GO:0010765	involved_in positive regulation of sodium ion transport	1	IMP	Homo_sapiens(9606)	Process
GO:0016324	located_in apical plasma membrane	1	ISS	Homo_sapiens(9606)	Component
GO:0031440	involved_in regulation of mRNA 3-end processing	1	IDA	Homo_sapiens(9606)	Process
GO:0032412	involved_in regulation of monoatomic ion transmembrane transporter activity	1	IMP	Homo_sapiens(9606)	Process
GO:0033353	involved_in S-adenosylmethionine cycle	1	IBA	Homo_sapiens(9606)	Process
GO:0038166	involved_in angiotensin-activated signaling pathway	1	IDA	Homo_sapiens(9606)	Process
GO:0042045	involved_in epithelial fluid transport	1	IEA	Homo_sapiens(9606)	Process
GO:0042802	enables identical protein binding	1	IPI	Homo_sapiens(9606)	Function
GO:0044070	involved_in regulation of monoatomic anion transport	1	IEA	Homo_sapiens(9606)	Process
GO:0044233	located_in mitochondria-associated endoplasmic reticulum membrane	1	IDA	Homo_sapiens(9606)	Component
GO:0051592	involved_in response to calcium ion	1	IDA	Homo_sapiens(9606)	Process
GO:0070062	located_in extracellular exosome	1	HDA	Homo_sapiens(9606)	Component
GO:1990456	involved_in mitochondrion-endoplasmic reticulum membrane tethering	1	IMP	Homo_sapiens(9606)	Process