RBP Type	Canonical_RBPs
Diseases	Cancer
Drug	N.A.
Main interacting RNAs	mRNA
Moonlighting functions	N.A.
Localizations	Stress granule or P-body
BulkPerturb-seq	N.A.

Ensembl ID	ENSG00000165494	Gene ID	51585	Accession	30097
Symbol	PCF11	Alias	NA	Full Name	PCF11 cleavage and polyadenylation factor subunit
Status	Confidence	Length	30464 bases	Strand	Plus strand
Position	11 : 83156988 - 83187451	RNA binding domain	CID
Summary	The protein encoded by this gene binds to CLP1 to form pre-mRNA cleavage factor IIm. The encoded protein is necessary for efficient Pol II transcription termination and may be involved in degradation of the 3' product of polyA site cleavage. [provided by RefSeq, Oct 2016]

Protein	Domain	Pfam ID	E-value	Domain number
ENSP00000431567	CID	PF04818	1e-13	1
ENSP00000434540	CID	PF04818	1.7e-13	1
ENSP00000298281	CID	PF04818	3.5e-13	1
ENSP00000508500	CID	PF04818	3.9e-13	1

Pubmed ID	Full Name	Cell	Author	Time	Doi

Pubmed ID	Title	Author	Time	Journal
25429106	Expression, purification, and identification of associated proteins of the full-length hCDK12/CyclinK complex.	Bartlomiej Bartkowiak	2015-01-16	The Journal of biological chemistry
31213387	Transcriptional Control by Premature Termination: A Forgotten Mechanism.	Kinga Kamieniarz-Gdula	2019-08-01	Trends in genetics : TIG
15241417	Recognition of RNA polymerase II carboxy-terminal domain by 3'-RNA-processing factors.	Anton Meinhart	2004-07-08	Nature
32295865	Requirement for cleavage factor IIm in the control of alternative polyadenylation in breast cancer cells.	E Rachael Turner	2020-08-01	RNA (New York, N.Y.)
30139799	Reconstitution of mammalian cleavage factor II involved in 3' processing of mRNA precursors.	Peter Schäfer	2018-12-01	RNA (New York, N.Y.)
15665873	Key features of the interaction between Pcf11 CID and RNA polymerase II CTD.	G Christian Noble	2005-02-01	Nature structural & molecular biology
30819644	Selective Roles of Vertebrate PCF11 in Premature and Full-Length Transcript Termination.	Kinga Kamieniarz-Gdula	2019-04-04	Molecular cell
27677860	Alternative polyadenylation of mRNA precursors.	Bin Tian	2017-01-01	Nature reviews. Molecular cell biology
30840896	Regulation of Intronic Polyadenylation by PCF11 Impacts mRNA Expression of Long Genes.	Ruijia Wang	2019-03-05	Cell reports
33526057	Alternative polyadenylation: methods, mechanism, function, and role in cancer.	Yi Zhang	2021-02-01	Journal of experimental & clinical cancer research : CR

Name	Transcript ID	bp	Protein	Translation ID
PCF11-201	ENST00000298281	7677	1555aa	ENSP00000298281
PCF11-204	ENST00000530660	3309	998aa	ENSP00000434540
PCF11-208	ENST00000690938	6270	1686aa	ENSP00000508500
PCF11-203	ENST00000530304	2649	784aa	ENSP00000431567
PCF11-206	ENST00000533018	580	99aa	ENSP00000436806
PCF11-207	ENST00000624931	1720	No protein	-
PCF11-205	ENST00000530906	628	198aa	ENSP00000437076
PCF11-202	ENST00000528336	1041	No protein	-

Pathway ID	Pathway Name	Source

ensgID	Trait	pValue	Pubmed ID
106630	Motor Activity	7E-6	23251661

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
ENSG00000165494

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
ENSG00000165494	homo_sapiens	ENSP00000508500	91.6963	91.4591	nomascus_leucogenys	ENSNLEP00000020090	99.4212	99.164
ENSG00000165494	homo_sapiens	ENSP00000508500	99.9407	99.8814	pan_paniscus	ENSPPAP00000002110	99.9407	99.8814
ENSG00000165494	homo_sapiens	ENSP00000508500	91.9929	91.8743	pongo_abelii	ENSPPYP00000028585	99.7428	99.6142
ENSG00000165494	homo_sapiens	ENSP00000508500	99.9407	99.8221	pan_troglodytes	ENSPTRP00000007096	99.9407	99.8221
ENSG00000165494	homo_sapiens	ENSP00000508500	99.9407	99.8814	gorilla_gorilla	ENSGGOP00000013368	100	99.9407
ENSG00000165494	homo_sapiens	ENSP00000508500	85.7058	78.5884	ornithorhynchus_anatinus	ENSOANP00000010456	87.2585	80.0121
ENSG00000165494	homo_sapiens	ENSP00000508500	93.5943	88.9087	sarcophilus_harrisii	ENSSHAP00000024721	93.1523	88.4888
ENSG00000165494	homo_sapiens	ENSP00000508500	77.4614	73.5469	notamacropus_eugenii	ENSMEUP00000004716	78.6273	74.6538
ENSG00000165494	homo_sapiens	ENSP00000508500	85.5872	83.6892	choloepus_hoffmanni	ENSCHOP00000006902	96.7807	94.6345
ENSG00000165494	homo_sapiens	ENSP00000508500	93.8909	91.9336	dasypus_novemcinctus	ENSDNOP00000009948	97.1762	95.1504
ENSG00000165494	homo_sapiens	ENSP00000508500	88.6121	85.8838	erinaceus_europaeus	ENSEEUP00000006276	90.4358	87.6513
ENSG00000165494	homo_sapiens	ENSP00000508500	83.9858	81.7319	echinops_telfairi	ENSETEP00000009851	86.7647	84.4363
ENSG00000165494	homo_sapiens	ENSP00000508500	98.9917	98.3986	callithrix_jacchus	ENSCJAP00000091311	98.9917	98.3986
ENSG00000165494	homo_sapiens	ENSP00000508500	99.5848	99.3476	cercocebus_atys	ENSCATP00000035630	99.5848	99.3476
ENSG00000165494	homo_sapiens	ENSP00000508500	99.4069	99.1103	macaca_fascicularis	ENSMFAP00000036705	99.4069	99.1103
ENSG00000165494	homo_sapiens	ENSP00000508500	94.7212	94.484	macaca_mulatta	ENSMMUP00000066682	99.4396	99.1905
ENSG00000165494	homo_sapiens	ENSP00000508500	99.5255	99.2883	macaca_nemestrina	ENSMNEP00000030748	99.5255	99.2883
ENSG00000165494	homo_sapiens	ENSP00000508500	99.5848	99.2883	papio_anubis	ENSPANP00000008841	96.8281	96.5398
ENSG00000165494	homo_sapiens	ENSP00000508500	91.8149	91.5777	mandrillus_leucophaeus	ENSMLEP00000005184	99.5498	99.2926
ENSG00000165494	homo_sapiens	ENSP00000508500	86.9514	85.4093	tursiops_truncatus	ENSTTRP00000001061	98.3233	96.5795
ENSG00000165494	homo_sapiens	ENSP00000508500	98.3393	97.2717	vulpes_vulpes	ENSVVUP00000023835	98.3393	97.2717
ENSG00000165494	homo_sapiens	ENSP00000508500	89.2052	86.3582	mus_spretus	MGP_SPRETEiJ_P0084036	96.8448	93.754
ENSG00000165494	homo_sapiens	ENSP00000508500	98.6951	97.3903	equus_asinus	ENSEASP00005018495	98.6951	97.3903
ENSG00000165494	homo_sapiens	ENSP00000508500	98.102	96.204	capra_hircus	ENSCHIP00000023348	98.1602	96.2611
ENSG00000165494	homo_sapiens	ENSP00000508500	88.6121	86.6548	loxodonta_africana	ENSLAFP00000000526	91.1531	89.1397
ENSG00000165494	homo_sapiens	ENSP00000508500	90.5694	89.3832	panthera_leo	ENSPLOP00000028285	98.1994	96.9132
ENSG00000165494	homo_sapiens	ENSP00000508500	98.28	97.2717	ailuropoda_melanoleuca	ENSAMEP00000027329	98.3383	97.3294
ENSG00000165494	homo_sapiens	ENSP00000508500	97.9241	96.1447	bos_indicus_hybrid	ENSBIXP00005015710	97.9822	96.2018
ENSG00000165494	homo_sapiens	ENSP00000508500	97.8648	96.3227	oryctolagus_cuniculus	ENSOCUP00000040337	97.981	96.4371
ENSG00000165494	homo_sapiens	ENSP00000508500	98.5765	97.2717	equus_caballus	ENSECAP00000039712	98.5765	97.2717
ENSG00000165494	homo_sapiens	ENSP00000508500	90.6287	89.739	canis_lupus_familiaris	ENSCAFP00845016762	98.2637	97.299
ENSG00000165494	homo_sapiens	ENSP00000508500	90.5694	89.3832	panthera_pardus	ENSPPRP00000001245	98.1994	96.9132
ENSG00000165494	homo_sapiens	ENSP00000508500	90.9253	89.6204	marmota_marmota_marmota	ENSMMMP00000007206	98.7122	97.2956
ENSG00000165494	homo_sapiens	ENSP00000508500	90.5694	89.2052	balaenoptera_musculus	ENSBMSP00010006758	98.2626	96.7825
ENSG00000165494	homo_sapiens	ENSP00000508500	89.8577	88.0783	cavia_porcellus	ENSCPOP00000003702	97.5531	95.6214
ENSG00000165494	homo_sapiens	ENSP00000508500	98.3986	97.153	felis_catus	ENSFCAP00000023990	98.3986	97.153
ENSG00000165494	homo_sapiens	ENSP00000508500	98.3986	97.3903	ursus_americanus	ENSUAMP00000011440	98.3986	97.3903
ENSG00000165494	homo_sapiens	ENSP00000508500	93.6536	89.0866	monodelphis_domestica	ENSMODP00000005550	93.1563	88.6136
ENSG00000165494	homo_sapiens	ENSP00000508500	90.2135	88.5528	bison_bison_bison	ENSBBBP00000024620	97.8764	96.0746
ENSG00000165494	homo_sapiens	ENSP00000508500	90.5101	88.968	monodon_monoceros	ENSMMNP00015023525	98.1982	96.5251
ENSG00000165494	homo_sapiens	ENSP00000508500	90.1542	88.8493	sus_scrofa	ENSSSCP00000015822	97.9381	96.5206
ENSG00000165494	homo_sapiens	ENSP00000508500	98.6358	97.5089	microcebus_murinus	ENSMICP00000008188	98.6944	97.5668
ENSG00000165494	homo_sapiens	ENSP00000508500	89.5611	87.4259	octodon_degus	ENSODEP00000005118	97.4194	95.0968
ENSG00000165494	homo_sapiens	ENSP00000508500	4.15184	3.85528	jaculus_jaculus	ENSJJAP00000007840	89.7436	83.3333
ENSG00000165494	homo_sapiens	ENSP00000508500	98.0427	96.204	ovis_aries_rambouillet	ENSOARP00020031602	98.1009	96.2611
ENSG00000165494	homo_sapiens	ENSP00000508500	98.0427	97.0344	ursus_maritimus	ENSUMAP00000032725	98.1009	97.092
ENSG00000165494	homo_sapiens	ENSP00000508500	73.7841	71.6489	ochotona_princeps	ENSOPRP00000003819	75.4397	73.2565
ENSG00000165494	homo_sapiens	ENSP00000508500	98.3393	96.6785	delphinapterus_leucas	ENSDLEP00000003515	98.3393	96.6785
ENSG00000165494	homo_sapiens	ENSP00000508500	98.4579	97.2123	physeter_catodon	ENSPCTP00005014523	98.4579	97.2123
ENSG00000165494	homo_sapiens	ENSP00000508500	89.1459	86.2989	mus_caroli	MGP_CAROLIEiJ_P0080671	96.7804	93.6896
ENSG00000165494	homo_sapiens	ENSP00000508500	89.2052	86.2989	mus_musculus	ENSMUSP00000113717	96.8448	93.6896
ENSG00000165494	homo_sapiens	ENSP00000508500	90.5101	88.6714	dipodomys_ordii	ENSDORP00000009446	98.1982	96.2033
ENSG00000165494	homo_sapiens	ENSP00000508500	90.2135	88.8493	mustela_putorius_furo	ENSMPUP00000008036	97.8135	96.3344
ENSG00000165494	homo_sapiens	ENSP00000508500	91.2811	90.7473	aotus_nancymaae	ENSANAP00000040773	99.0348	98.4556
ENSG00000165494	homo_sapiens	ENSP00000508500	91.2218	90.688	saimiri_boliviensis_boliviensis	ENSSBOP00000002958	98.9704	98.3913
ENSG00000165494	homo_sapiens	ENSP00000508500	78.8849	77.0463	vicugna_pacos	ENSVPAP00000007208	82.8144	80.8842
ENSG00000165494	homo_sapiens	ENSP00000508500	91.8743	91.6963	chlorocebus_sabaeus	ENSCSAP00000000071	99.6142	99.4212
ENSG00000165494	homo_sapiens	ENSP00000508500	73.6062	72.0641	tupaia_belangeri	ENSTBEP00000015237	75.1211	73.5472
ENSG00000165494	homo_sapiens	ENSP00000508500	89.5611	87.3665	mesocricetus_auratus	ENSMAUP00000024610	97.1686	94.7876
ENSG00000165494	homo_sapiens	ENSP00000508500	98.3986	96.7378	phocoena_sinus	ENSPSNP00000029594	98.3986	96.7378
ENSG00000165494	homo_sapiens	ENSP00000508500	90.866	89.2052	camelus_dromedarius	ENSCDRP00005000363	98.5209	96.7203
ENSG00000165494	homo_sapiens	ENSP00000508500	98.0427	96.8565	carlito_syrichta	ENSTSYP00000000128	98.5689	97.3763
ENSG00000165494	homo_sapiens	ENSP00000508500	90.0949	88.968	panthera_tigris_altaica	ENSPTIP00000008689	98.1266	96.8992
ENSG00000165494	homo_sapiens	ENSP00000508500	97.153	94.3061	rattus_norvegicus	ENSRNOP00000092470	87.7343	85.1634
ENSG00000165494	homo_sapiens	ENSP00000508500	91.0439	89.7983	prolemur_simus	ENSPSMP00000034064	98.6504	97.3008
ENSG00000165494	homo_sapiens	ENSP00000508500	88.5528	85.8838	microtus_ochrogaster	ENSMOCP00000002000	96.1985	93.299
ENSG00000165494	homo_sapiens	ENSP00000508500	84.5196	82.4437	sorex_araneus	ENSSARP00000001943	87.156	85.0153
ENSG00000165494	homo_sapiens	ENSP00000508500	5.51601	4.86358	peromyscus_maniculatus_bairdii	ENSPEMP00000036557	70.4545	62.1212
ENSG00000165494	homo_sapiens	ENSP00000508500	4.21115	3.91459	peromyscus_maniculatus_bairdii	ENSPEMP00000030189	91.0256	84.6154
ENSG00000165494	homo_sapiens	ENSP00000508500	3.20285	2.90629	peromyscus_maniculatus_bairdii	ENSPEMP00000030864	65.8537	59.7561
ENSG00000165494	homo_sapiens	ENSP00000508500	90.0949	88.3749	bos_mutus	ENSBMUP00000014225	97.6849	95.8199
ENSG00000165494	homo_sapiens	ENSP00000508500	89.0273	86.1803	mus_spicilegus	ENSMSIP00000021978	96.6516	93.5609
ENSG00000165494	homo_sapiens	ENSP00000508500	89.6204	87.4259	cricetulus_griseus_chok1gshd	ENSCGRP00001013467	97.2956	94.9131
ENSG00000165494	homo_sapiens	ENSP00000508500	86.4176	85.1127	pteropus_vampyrus	ENSPVAP00000005164	88.1428	86.8119
ENSG00000165494	homo_sapiens	ENSP00000508500	89.6797	87.7224	myotis_lucifugus	ENSMLUP00000011877	91.9149	89.9088
ENSG00000165494	homo_sapiens	ENSP00000508500	67.0225	64.7094	myotis_lucifugus	ENSMLUP00000013920	95.1178	91.835
ENSG00000165494	homo_sapiens	ENSP00000508500	92.7639	88.3155	vombatus_ursinus	ENSVURP00010008531	92.435	88.0024
ENSG00000165494	homo_sapiens	ENSP00000508500	97.9241	96.204	rhinolophus_ferrumequinum	ENSRFEP00010015330	98.0986	96.3755
ENSG00000165494	homo_sapiens	ENSP00000508500	97.9834	96.382	neovison_vison	ENSNVIP00000001706	97.9834	96.382
ENSG00000165494	homo_sapiens	ENSP00000508500	97.9241	96.1447	bos_taurus	ENSBTAP00000020320	97.9822	96.2018
ENSG00000165494	homo_sapiens	ENSP00000508500	97.5682	95.7888	heterocephalus_glaber_female	ENSHGLP00000003353	97.8584	96.0738
ENSG00000165494	homo_sapiens	ENSP00000508500	98.4579	98.102	rhinopithecus_bieti	ENSRBIP00000009379	99.4012	99.0419
ENSG00000165494	homo_sapiens	ENSP00000508500	98.3986	97.5089	canis_lupus_dingo	ENSCAFP00020022639	98.3986	97.5089
ENSG00000165494	homo_sapiens	ENSP00000508500	90.866	89.3238	sciurus_vulgaris	ENSSVLP00005019635	98.5843	96.9112
ENSG00000165494	homo_sapiens	ENSP00000508500	92.8826	88.3749	phascolarctos_cinereus	ENSPCIP00000037371	92.5532	88.0615
ENSG00000165494	homo_sapiens	ENSP00000508500	87.2479	85.2906	procavia_capensis	ENSPCAP00000003277	89.0975	87.0987
ENSG00000165494	homo_sapiens	ENSP00000508500	89.917	87.6038	nannospalax_galili	ENSNGAP00000005487	97.5547	95.045
ENSG00000165494	homo_sapiens	ENSP00000508500	90.0949	88.3749	bos_grunniens	ENSBGRP00000034590	97.7477	95.8816
ENSG00000165494	homo_sapiens	ENSP00000508500	97.7461	96.0854	chinchilla_lanigera	ENSCLAP00000020190	97.8622	96.1995
ENSG00000165494	homo_sapiens	ENSP00000508500	98.102	96.3227	cervus_hanglu_yarkandensis	ENSCHYP00000005348	98.1602	96.3798
ENSG00000165494	homo_sapiens	ENSP00000508500	90.0356	88.7307	catagonus_wagneri	ENSCWAP00000000232	97.8093	96.3918
ENSG00000165494	homo_sapiens	ENSP00000508500	98.6951	97.2123	ictidomys_tridecemlineatus	ENSSTOP00000004945	98.8124	97.3278
ENSG00000165494	homo_sapiens	ENSP00000508500	90.9253	89.5018	otolemur_garnettii	ENSOGAP00000001698	93.2482	91.7883
ENSG00000165494	homo_sapiens	ENSP00000508500	99.051	98.4579	cebus_imitator	ENSCCAP00000007871	99.051	98.4579
ENSG00000165494	homo_sapiens	ENSP00000508500	98.6951	97.2123	urocitellus_parryii	ENSUPAP00010022140	98.7537	97.27
ENSG00000165494	homo_sapiens	ENSP00000508500	97.9241	96.0261	moschus_moschiferus	ENSMMSP00000005840	97.9822	96.0831
ENSG00000165494	homo_sapiens	ENSP00000508500	99.6441	99.2289	rhinopithecus_roxellana	ENSRROP00000009312	97.7881	97.3807
ENSG00000165494	homo_sapiens	ENSP00000508500	89.0866	86.2989	mus_pahari	MGP_PahariEiJ_P0017512	96.716	93.6896
ENSG00000165494	homo_sapiens	ENSP00000508500	90.688	89.2052	propithecus_coquereli	ENSPCOP00000000025	98.2648	96.6581
ENSG00000165494	homo_sapiens	ENSP00000508500	10.261	6.58363	caenorhabditis_elegans	R144.2a.2	21.0207	13.4872
ENSG00000165494	homo_sapiens	ENSP00000508500	15.4804	9.01542	drosophila_melanogaster	FBpp0291500	13.3641	7.7829
ENSG00000165494	homo_sapiens	ENSP00000508500	8.4223	5.87189	ciona_intestinalis	ENSCINP00000015040	63.964	44.5946
ENSG00000165494	homo_sapiens	ENSP00000508500	21.5302	11.2693	ciona_intestinalis	ENSCINP00000006826	42.3077	22.1445
ENSG00000165494	homo_sapiens	ENSP00000508500	35.8837	27.8173	eptatretus_burgeri	ENSEBUP00000005002	62.8898	48.7526
ENSG00000165494	homo_sapiens	ENSP00000508500	58.8968	44.7805	callorhinchus_milii	ENSCMIP00000036164	54.292	41.2794
ENSG00000165494	homo_sapiens	ENSP00000508500	64.4128	54.745	latimeria_chalumnae	ENSLACP00000010050	70.7492	60.1303
ENSG00000165494	homo_sapiens	ENSP00000508500	58.7189	47.0344	lepisosteus_oculatus	ENSLOCP00000007131	61.1111	48.9506
ENSG00000165494	homo_sapiens	ENSP00000508500	50.7117	38.6121	clupea_harengus	ENSCHAP00000021594	55.2683	42.0814
ENSG00000165494	homo_sapiens	ENSP00000508500	49.2883	38.7307	danio_rerio	ENSDARP00000065561	57.035	44.8181
ENSG00000165494	homo_sapiens	ENSP00000508500	50.8304	39.1459	carassius_auratus	ENSCARP00000073429	58.7791	45.2675
ENSG00000165494	homo_sapiens	ENSP00000508500	50.8897	39.2052	carassius_auratus	ENSCARP00000135322	58.8477	45.3361
ENSG00000165494	homo_sapiens	ENSP00000508500	51.898	40.9846	astyanax_mexicanus	ENSAMXP00000005175	58.3722	46.0974
ENSG00000165494	homo_sapiens	ENSP00000508500	51.1269	39.6797	ictalurus_punctatus	ENSIPUP00000001428	57.8912	44.9295
ENSG00000165494	homo_sapiens	ENSP00000508500	40.2728	30.6643	esox_lucius	ENSELUP00000031679	49.5982	37.7648
ENSG00000165494	homo_sapiens	ENSP00000508500	52.4911	40.3321	electrophorus_electricus	ENSEEEP00000008141	59.6763	45.853
ENSG00000165494	homo_sapiens	ENSP00000508500	52.9656	42.1115	oncorhynchus_kisutch	ENSOKIP00005091215	52.809	41.987
ENSG00000165494	homo_sapiens	ENSP00000508500	52.847	41.7556	oncorhynchus_mykiss	ENSOMYP00000104957	52.5664	41.5339
ENSG00000165494	homo_sapiens	ENSP00000508500	50	40.8066	salmo_salar	ENSSSAP00000034848	57.308	46.7709
ENSG00000165494	homo_sapiens	ENSP00000508500	52.6097	41.3998	salmo_trutta	ENSSTUP00000008767	52.2379	41.1072
ENSG00000165494	homo_sapiens	ENSP00000508500	49.3476	38.3155	fundulus_heteroclitus	ENSFHEP00000004732	52.36	40.6545
ENSG00000165494	homo_sapiens	ENSP00000508500	3.91459	2.90629	poecilia_reticulata	ENSPREP00000002252	75.8621	56.3218
ENSG00000165494	homo_sapiens	ENSP00000508500	49.4069	38.4935	xiphophorus_maculatus	ENSXMAP00000006895	49.2608	38.3797
ENSG00000165494	homo_sapiens	ENSP00000508500	46.6192	35.6465	oryzias_latipes	ENSORLP00000017214	52.47	40.1202
ENSG00000165494	homo_sapiens	ENSP00000508500	46.382	36.0617	cyclopterus_lumpus	ENSCLMP00005017472	52.2727	40.6417
ENSG00000165494	homo_sapiens	ENSP00000508500	3.55872	2.60973	oreochromis_niloticus	ENSONIP00000045236	60	44
ENSG00000165494	homo_sapiens	ENSP00000508500	3.61803	2.84698	haplochromis_burtoni	ENSHBUP00000017457	60.396	47.5248
ENSG00000165494	homo_sapiens	ENSP00000508500	3.44009	2.78766	astatotilapia_calliptera	ENSACLP00000000691	56.8627	46.0784
ENSG00000165494	homo_sapiens	ENSP00000508500	36.9514	27.1649	astatotilapia_calliptera	ENSACLP00000000705	47.2328	34.7233
ENSG00000165494	homo_sapiens	ENSP00000508500	49.8814	39.0273	sparus_aurata	ENSSAUP00010019348	50.4802	39.4958
ENSG00000165494	homo_sapiens	ENSP00000508500	42.2894	32.8588	lates_calcarifer	ENSLCAP00010047866	54.5524	42.3871
ENSG00000165494	homo_sapiens	ENSP00000508500	65.7177	54.9229	xenopus_tropicalis	ENSXETP00000060768	65.2532	54.5347
ENSG00000165494	homo_sapiens	ENSP00000508500	82.8588	75.2669	chrysemys_picta_bellii	ENSCPBP00000008823	79.8742	72.5557
ENSG00000165494	homo_sapiens	ENSP00000508500	77.1649	69.9881	crocodylus_porosus	ENSCPRP00005023336	81.8239	74.2138
ENSG00000165494	homo_sapiens	ENSP00000508500	76.038	66.1329	laticauda_laticaudata	ENSLLTP00000006758	74.0185	64.3764
ENSG00000165494	homo_sapiens	ENSP00000508500	76.038	66.4887	notechis_scutatus	ENSNSUP00000025900	76.2641	66.6865
ENSG00000165494	homo_sapiens	ENSP00000508500	76.1566	66.2515	pseudonaja_textilis	ENSPTXP00000004874	74.0058	64.3804
ENSG00000165494	homo_sapiens	ENSP00000508500	66.3108	58.7189	anas_platyrhynchos_platyrhynchos	ENSAPLP00000012015	76.0544	67.3469
ENSG00000165494	homo_sapiens	ENSP00000508500	78.0546	69.7509	gallus_gallus	ENSGALP00010010598	77.8698	69.5858
ENSG00000165494	homo_sapiens	ENSP00000508500	74.3772	66.3701	meleagris_gallopavo	ENSMGAP00000016161	77.312	68.9889
ENSG00000165494	homo_sapiens	ENSP00000508500	78.7663	69.9288	serinus_canaria	ENSSCAP00000003515	74.5648	66.1988
ENSG00000165494	homo_sapiens	ENSP00000508500	78.9442	70.5219	parus_major	ENSPMJP00000001354	78.2941	69.9412
ENSG00000165494	homo_sapiens	ENSP00000508500	3.44009	2.72835	neolamprologus_brichardi	ENSNBRP00000022888	58	46
ENSG00000165494	homo_sapiens	ENSP00000508500	74.2586	64.5314	naja_naja	ENSNNAP00000010762	76.8098	66.7485
ENSG00000165494	homo_sapiens	ENSP00000508500	77.0463	68.0308	podarcis_muralis	ENSPMRP00000002656	73.6395	65.0227
ENSG00000165494	homo_sapiens	ENSP00000508500	78.1139	69.2171	geospiza_fortis	ENSGFOP00000007692	80.3049	71.1585
ENSG00000165494	homo_sapiens	ENSP00000508500	78.8256	69.6916	taeniopygia_guttata	ENSTGUP00000023555	78.4071	69.3215
ENSG00000165494	homo_sapiens	ENSP00000508500	59.2527	47.5089	erpetoichthys_calabaricus	ENSECRP00000013961	57.0531	45.7453
ENSG00000165494	homo_sapiens	ENSP00000508500	48.7544	38.1376	kryptolebias_marmoratus	ENSKMAP00000002462	52.4235	41.0077
ENSG00000165494	homo_sapiens	ENSP00000508500	77.0463	67.0225	salvator_merianae	ENSSMRP00000009518	75.7876	65.9277
ENSG00000165494	homo_sapiens	ENSP00000508500	4.09253	3.14353	amphilophus_citrinellus	ENSACIP00000031385	81.1765	62.3529
ENSG00000165494	homo_sapiens	ENSP00000508500	50.4745	39.5018	dicentrarchus_labrax	ENSDLAP00005028205	51.5133	40.3148
ENSG00000165494	homo_sapiens	ENSP00000508500	50.949	38.968	amphiprion_percula	ENSAPEP00000029440	53.7547	41.1139
ENSG00000165494	homo_sapiens	ENSP00000508500	46.7378	35.5279	oryzias_sinensis	ENSOSIP00000031772	52.6738	40.0401
ENSG00000165494	homo_sapiens	ENSP00000508500	75.089	66.9039	pelodiscus_sinensis	ENSPSIP00000003251	80.8946	72.0767
ENSG00000165494	homo_sapiens	ENSP00000508500	82.2657	74.5552	gopherus_evgoodei	ENSGEVP00005002462	79.3025	71.8696
ENSG00000165494	homo_sapiens	ENSP00000508500	79.4781	71.5896	chelonoidis_abingdonii	ENSCABP00000029524	78.6385	70.8333
ENSG00000165494	homo_sapiens	ENSP00000508500	49.1696	39.0273	seriola_dumerili	ENSSDUP00000032564	50.9214	40.4177
ENSG00000165494	homo_sapiens	ENSP00000508500	47.0344	36.5955	cottoperca_gobio	ENSCGOP00000006533	54.9931	42.7878
ENSG00000165494	homo_sapiens	ENSP00000508500	75.6821	67.675	struthio_camelus_australis	ENSSCUP00000018304	80.3021	71.8062
ENSG00000165494	homo_sapiens	ENSP00000508500	79.0036	71.0558	anser_brachyrhynchus	ENSABRP00000010381	78.91	70.9716
ENSG00000165494	homo_sapiens	ENSP00000508500	44.8399	34.4603	gasterosteus_aculeatus	ENSGACP00000027636	54.9419	42.2238
ENSG00000165494	homo_sapiens	ENSP00000508500	4.21115	3.32147	cynoglossus_semilaevis	ENSCSEP00000009916	71.7172	56.5657
ENSG00000165494	homo_sapiens	ENSP00000508500	32.1471	24.3179	cynoglossus_semilaevis	ENSCSEP00000009901	48.8288	36.9369
ENSG00000165494	homo_sapiens	ENSP00000508500	49.6441	38.8493	poecilia_formosa	ENSPFOP00000000913	51.5077	40.3077
ENSG00000165494	homo_sapiens	ENSP00000508500	51.1269	40.6287	myripristis_murdjan	ENSMMDP00005031005	52.7217	41.896
ENSG00000165494	homo_sapiens	ENSP00000508500	50.4745	39.4425	sander_lucioperca	ENSSLUP00000010572	52.1446	40.7475
ENSG00000165494	homo_sapiens	ENSP00000508500	79.1815	70.8185	strigops_habroptila	ENSSHBP00005001931	78.4832	70.194
ENSG00000165494	homo_sapiens	ENSP00000508500	50.949	38.9087	amphiprion_ocellaris	ENSAOCP00000008300	53.8221	41.1028
ENSG00000165494	homo_sapiens	ENSP00000508500	78.8256	71.7082	terrapene_carolina_triunguis	ENSTMTP00000022327	79.2487	72.093
ENSG00000165494	homo_sapiens	ENSP00000508500	40.9253	31.6133	hucho_hucho	ENSHHUP00000040100	48.218	37.2467
ENSG00000165494	homo_sapiens	ENSP00000508500	48.6358	36.4769	betta_splendens	ENSBSLP00000013802	53.1432	39.8574
ENSG00000165494	homo_sapiens	ENSP00000508500	52.3725	41.2218	pygocentrus_nattereri	ENSPNAP00000008784	59.0241	46.4572
ENSG00000165494	homo_sapiens	ENSP00000508500	50	38.8493	anabas_testudineus	ENSATEP00000015507	53.4221	41.5082
ENSG00000165494	homo_sapiens	ENSP00000508500	22.6572	14.2942	ciona_savignyi	ENSCSAVP00000013669	52.8354	33.3333
ENSG00000165494	homo_sapiens	ENSP00000508500	10.7948	6.70225	ciona_savignyi	ENSCSAVP00000011476	50.838	31.5642
ENSG00000165494	homo_sapiens	ENSP00000508500	15.9549	9.25267	saccharomyces_cerevisiae	YDR228C	42.9712	24.9201
ENSG00000165494	homo_sapiens	ENSP00000508500	3.14353	2.78766	seriola_lalandi_dorsalis	ENSSLDP00000023146	73.6111	65.2778
ENSG00000165494	homo_sapiens	ENSP00000508500	3.61803	2.84698	seriola_lalandi_dorsalis	ENSSLDP00000000935	57.0093	44.8598
ENSG00000165494	homo_sapiens	ENSP00000508500	3.67734	2.78766	labrus_bergylta	ENSLBEP00000007773	65.2632	49.4737
ENSG00000165494	homo_sapiens	ENSP00000508500	3.9739	3.02491	labrus_bergylta	ENSLBEP00000002057	63.2075	48.1132
ENSG00000165494	homo_sapiens	ENSP00000508500	35.1127	26.2159	pundamilia_nyererei	ENSPNYP00000030041	47.512	35.4735
ENSG00000165494	homo_sapiens	ENSP00000508500	3.55872	2.60973	pundamilia_nyererei	ENSPNYP00000030066	60	44
ENSG00000165494	homo_sapiens	ENSP00000508500	45.9668	35.4093	mastacembelus_armatus	ENSMAMP00000067167	56.4047	43.4498
ENSG00000165494	homo_sapiens	ENSP00000508500	50.5338	39.0273	stegastes_partitus	ENSSPAP00000014915	52.3985	40.4674
ENSG00000165494	homo_sapiens	ENSP00000508500	52.847	41.7556	oncorhynchus_tshawytscha	ENSOTSP00005037179	52.5354	41.5094
ENSG00000165494	homo_sapiens	ENSP00000508500	50.8304	38.968	acanthochromis_polyacanthus	ENSAPOP00000032660	53.6631	41.1396
ENSG00000165494	homo_sapiens	ENSP00000508500	79.4187	71.1151	aquila_chrysaetos_chrysaetos	ENSACCP00020012502	78.3958	70.1991
ENSG00000165494	homo_sapiens	ENSP00000508500	46.9158	36.7141	nothobranchius_furzeri	ENSNFUP00015033641	57.1945	44.7578
ENSG00000165494	homo_sapiens	ENSP00000508500	4.38909	3.20285	cyprinodon_variegatus	ENSCVAP00000017481	58.7302	42.8571
ENSG00000165494	homo_sapiens	ENSP00000508500	37.6038	28.8256	cyprinodon_variegatus	ENSCVAP00000017491	49.6865	38.0878
ENSG00000165494	homo_sapiens	ENSP00000508500	50.1779	39.4425	denticeps_clupeoides	ENSDCDP00000016929	58.2645	45.7989
ENSG00000165494	homo_sapiens	ENSP00000508500	50.5338	39.2645	larimichthys_crocea	ENSLCRP00005024240	52.8208	41.0415
ENSG00000165494	homo_sapiens	ENSP00000508500	46.204	35.5279	takifugu_rubripes	ENSTRUP00000010505	51.7608	39.8007
ENSG00000165494	homo_sapiens	ENSP00000508500	76.3938	67.675	ficedula_albicollis	ENSFALP00000026610	70.9251	62.8304
ENSG00000165494	homo_sapiens	ENSP00000508500	28.5291	19.8695	hippocampus_comes	ENSHCOP00000002946	41.6811	29.0295
ENSG00000165494	homo_sapiens	ENSP00000508500	3.67734	2.84698	hippocampus_comes	ENSHCOP00000002926	63.2653	48.9796
ENSG00000165494	homo_sapiens	ENSP00000508500	50.949	39.2052	cyprinus_carpio_carpio	ENSCCRP00000068574	58.8356	45.274
ENSG00000165494	homo_sapiens	ENSP00000508500	51.0676	38.7307	cyprinus_carpio_carpio	ENSCCRP00000108236	57.6691	43.7374
ENSG00000165494	homo_sapiens	ENSP00000508500	3.55872	3.02491	coturnix_japonica	ENSCJPP00005004129	71.4286	60.7143
ENSG00000165494	homo_sapiens	ENSP00000508500	49.7628	38.8493	poecilia_latipinna	ENSPLAP00000012153	51.6308	40.3077
ENSG00000165494	homo_sapiens	ENSP00000508500	51.1269	39.2645	sinocyclocheilus_grahami	ENSSGRP00000097896	59.0007	45.3114
ENSG00000165494	homo_sapiens	ENSP00000508500	51.1862	38.968	sinocyclocheilus_grahami	ENSSGRP00000028503	58.9078	44.8464
ENSG00000165494	homo_sapiens	ENSP00000508500	3.61803	2.84698	maylandia_zebra	ENSMZEP00005037300	60.396	47.5248
ENSG00000165494	homo_sapiens	ENSP00000508500	42.7046	32.503	tetraodon_nigroviridis	ENSTNIP00000006688	54.2986	41.3273
ENSG00000165494	homo_sapiens	ENSP00000508500	46.1447	35.6465	tetraodon_nigroviridis	ENSTNIP00000007432	56.2139	43.4249
ENSG00000165494	homo_sapiens	ENSP00000508500	54.567	44.4247	paramormyrops_kingsleyae	ENSPKIP00000036671	58.5614	47.6766
ENSG00000165494	homo_sapiens	ENSP00000508500	55.2788	44.1874	scleropages_formosus	ENSSFOP00015008533	59.7436	47.7564
ENSG00000165494	homo_sapiens	ENSP00000508500	64.6501	53.2028	leptobrachium_leishanense	ENSLLEP00000007091	64.8038	53.3294
ENSG00000165494	homo_sapiens	ENSP00000508500	47.331	36.8921	scophthalmus_maximus	ENSSMAP00000069306	56.0393	43.6798
ENSG00000165494	homo_sapiens	ENSP00000508500	45.8482	36.4176	oryzias_melastigma	ENSOMEP00000032389	52.7645	41.9113

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0000993	enables RNA polymerase II complex binding	2	IBA,IDA	Homo_sapiens(9606)	Function
GO:0003729	enables mRNA binding	1	IBA	Homo_sapiens(9606)	Function
GO:0005634	is_active_in nucleus	1	IDA	Homo_sapiens(9606)	Component
GO:0005654	located_in nucleoplasm	2	IDA,TAS	Homo_sapiens(9606)	Component
GO:0005737	is_active_in cytoplasm	1	IBA	Homo_sapiens(9606)	Component
GO:0005739	located_in mitochondrion	1	IDA	Homo_sapiens(9606)	Component
GO:0005849	part_of mRNA cleavage factor complex	2	IBA,NAS	Homo_sapiens(9606)	Component
GO:0006369	involved_in termination of RNA polymerase II transcription	2	IBA,IDA	Homo_sapiens(9606)	Process
GO:0006378	involved_in mRNA polyadenylation	1	IBA	Homo_sapiens(9606)	Process
GO:0180010	involved_in co-transcriptional mRNA 3-end processing, cleavage and polyadenylation pathway	1	NAS	Homo_sapiens(9606)	Process