Functions and Diseases

RBP Type Non-canonical_RBPs
Diseases N.A.
Drug Drug
Main interacting RNAs N.A.
Moonlighting functions Kinase
Localizations N.A.
BulkPerturb-seq

Description

Ensembl ID ENSG00000164078 Gene ID 4486 Accession 7381
Symbol MST1R Alias RON;SEA;PTK8;CD136;NPCA3;CDw136;p185-Ron Full Name macrophage stimulating 1 receptor
Status Confidence Length 16872 bases Strand Minus strand
Position 3 : 49887002 - 49903873 RNA binding domain N.A.
Summary This gene encodes a cell surface receptor for macrophage-stimulating protein (MSP) with tyrosine kinase activity. The mature form of this protein is a heterodimer of disulfide-linked alpha and beta subunits, generated by proteolytic cleavage of a single-chain precursor. The beta subunit undergoes tyrosine phosphorylation upon stimulation by MSP. This protein is expressed on the ciliated epithelia of the mucociliary transport apparatus of the lung, and together with MSP, thought to be involved in host defense. Alternative splicing generates multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing. [provided by RefSeq, Jan 2016]

RNA binding proteomes (RBPomes)

Transcripts

Protein-Protein Interaction (PPI)

Paralogs

Orthologs

Gene Ontology

Expression