RBP Type	Canonical_RBPs
Diseases	N.A.
Drug	N.A.
Main interacting RNAs	N.A.
Moonlighting functions	Kinase
Localizations	N.A.
BulkPerturb-seq

Ensembl ID	ENSG00000163545	Gene ID	81788	Accession	29558
Symbol	NUAK2	Alias	ANPH2;SNARK	Full Name	NUAK family kinase 2
Status	Confidence	Length	19683 bases	Strand	Minus strand
Position	1 : 205302063 - 205321745	RNA binding domain	RIO1
Summary	Enables ATP binding activity; magnesium ion binding activity; and protein serine/threonine kinase activity. Involved in several processes, including cellular response to glucose starvation; negative regulation of apoptotic process; and protein phosphorylation. Predicted to be active in cytoplasm. Implicated in anencephaly. [provided by Alliance of Genome Resources, Apr 2022]

Protein	Domain	Pfam ID	E-value	Domain number
ENSP00000356125	RIO1	PF01163	0.00012	1

Pubmed ID	Full Name	Cell	Author	Time	Doi

Pubmed ID	Title	Author	Time	Journal

Name	Transcript ID	bp	Protein	Translation ID
NUAK2-201	ENST00000367157	3391	628aa	ENSP00000356125

Pathway ID	Pathway Name	Source

ensgID	Trait	pValue	Pubmed ID

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0000287	enables magnesium ion binding	1	IDA	Homo_sapiens(9606)	Function
GO:0004674	enables protein serine/threonine kinase activity	3	IBA,IDA,IMP	Homo_sapiens(9606)	Function
GO:0005515	enables protein binding	1	IPI	Homo_sapiens(9606)	Function
GO:0005524	enables ATP binding	1	IDA	Homo_sapiens(9606)	Function
GO:0006468	involved_in protein phosphorylation	2	IBA,IDA	Homo_sapiens(9606)	Process
GO:0006915	involved_in apoptotic process	1	IEA	Homo_sapiens(9606)	Process
GO:0030036	involved_in actin cytoskeleton organization	1	IDA	Homo_sapiens(9606)	Process
GO:0031588	part_of nucleotide-activated protein kinase complex	1	IBA	Homo_sapiens(9606)	Component
GO:0032007	involved_in negative regulation of TOR signaling	1	IBA	Homo_sapiens(9606)	Process
GO:0034504	involved_in protein localization to nucleus	1	IMP	Homo_sapiens(9606)	Process
GO:0035330	involved_in regulation of hippo signaling	1	IMP	Homo_sapiens(9606)	Process
GO:0035556	involved_in intracellular signal transduction	1	IBA	Homo_sapiens(9606)	Process
GO:0042149	involved_in cellular response to glucose starvation	2	IBA,IDA	Homo_sapiens(9606)	Process
GO:0043066	involved_in negative regulation of apoptotic process	1	IDA	Homo_sapiens(9606)	Process
GO:0106310	enables protein serine kinase activity	1	IEA	Homo_sapiens(9606)	Function