RBP Type	Canonical_RBPs
Diseases	N.A.
Drug	N.A.
Main interacting RNAs	rRNA
Moonlighting functions	N.A.
Localizations	N.A.
BulkPerturb-seq	N.A.

Ensembl ID	ENSG00000163319	Gene ID	51023	Accession	16633
Symbol	MRPS18C	Alias	bS18m;CGI-134;S18mt-c;MRPS18-1;mrps18-c;MRP-S18-1;MRP-S18-c	Full Name	mitochondrial ribosomal protein S18C
Status	Confidence	Length	11522 bases	Strand	Plus strand
Position	4 : 83455983 - 83467504	RNA binding domain	Ribosomal_S18
Summary	Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S18P family. The encoded protein is one of three that has significant sequence similarity to bacterial S18 proteins. The primary sequences of the three human mitochondrial S18 proteins are no more closely related to each other than they are to the prokaryotic S18 proteins. Pseudogenes corresponding to this gene are found on chromosomes 8p, 12p, 15q, and 22q. [provided by RefSeq, Jul 2008]

Protein	Domain	Pfam ID	E-value	Domain number
ENSP00000295491	Ribosomal_S18	PF01084	1.1e-22	1
ENSP00000427014	Ribosomal_S18	PF01084	4.6e-17	1
ENSP00000427169	Ribosomal_S18	PF01084	4.8e-17	1

Pubmed ID	Full Name	Cell	Author	Time	Doi

Pubmed ID	Title	Author	Time	Journal

Name	Transcript ID	bp	Protein	Translation ID
MRPS18C-208	ENST00000512375	2482	No protein	-
MRPS18C-204	ENST00000507019	666	114aa	ENSP00000427169
MRPS18C-205	ENST00000507349	350	68aa	ENSP00000426930
MRPS18C-201	ENST00000295491	1550	142aa	ENSP00000295491
MRPS18C-207	ENST00000509970	855	113aa	ENSP00000427014
MRPS18C-203	ENST00000505719	490	92aa	ENSP00000425268
MRPS18C-202	ENST00000505525	442	No protein	-
MRPS18C-209	ENST00000514581	301	No protein	-
MRPS18C-206	ENST00000509571	442	No protein	-

Pathway ID	Pathway Name	Source

ensgID	Trait	pValue	Pubmed ID
21466	Extraversion (Psychology)	3.601e-005	-

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
ENSG00000163319

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
ENSG00000163319	homo_sapiens	ENSP00000295491	97.8873	96.4789	nomascus_leucogenys	ENSNLEP00000035901	96.5278	95.1389
ENSG00000163319	homo_sapiens	ENSP00000295491	100	100	pan_paniscus	ENSPPAP00000028132	100	100
ENSG00000163319	homo_sapiens	ENSP00000295491	98.5916	97.8873	pongo_abelii	ENSPPYP00000023496	97.2222	96.5278
ENSG00000163319	homo_sapiens	ENSP00000295491	100	100	pan_troglodytes	ENSPTRP00000027890	100	100
ENSG00000163319	homo_sapiens	ENSP00000295491	84.507	83.8028	gorilla_gorilla	ENSGGOP00000008410	98.3607	97.541
ENSG00000163319	homo_sapiens	ENSP00000295491	82.3944	72.5352	sarcophilus_harrisii	ENSSHAP00000008176	81.8182	72.028
ENSG00000163319	homo_sapiens	ENSP00000295491	47.1831	40.1408	dasypus_novemcinctus	ENSDNOP00000017708	76.1364	64.7727
ENSG00000163319	homo_sapiens	ENSP00000295491	66.9014	61.9718	erinaceus_europaeus	ENSEEUP00000003207	65.9722	61.1111
ENSG00000163319	homo_sapiens	ENSP00000295491	59.8592	57.7465	echinops_telfairi	ENSETEP00000009914	60.7143	58.5714
ENSG00000163319	homo_sapiens	ENSP00000295491	82.3944	76.7606	callithrix_jacchus	ENSCJAP00000071389	73.125	68.125
ENSG00000163319	homo_sapiens	ENSP00000295491	98.5916	96.4789	cercocebus_atys	ENSCATP00000035693	97.2222	95.1389
ENSG00000163319	homo_sapiens	ENSP00000295491	97.1831	95.0704	macaca_fascicularis	ENSMFAP00000052780	95.8333	93.75
ENSG00000163319	homo_sapiens	ENSP00000295491	97.1831	95.0704	macaca_mulatta	ENSMMUP00000020133	95.8333	93.75
ENSG00000163319	homo_sapiens	ENSP00000295491	97.1831	95.0704	macaca_nemestrina	ENSMNEP00000041691	95.8333	93.75
ENSG00000163319	homo_sapiens	ENSP00000295491	78.8732	76.0563	papio_anubis	ENSPANP00000040813	95.7265	92.3077
ENSG00000163319	homo_sapiens	ENSP00000295491	97.1831	95.0704	papio_anubis	ENSPANP00000045408	95.8333	93.75
ENSG00000163319	homo_sapiens	ENSP00000295491	98.5916	96.4789	mandrillus_leucophaeus	ENSMLEP00000029353	97.2222	95.1389
ENSG00000163319	homo_sapiens	ENSP00000295491	90.8451	85.9155	tursiops_truncatus	ENSTTRP00000004616	90.2098	85.3147
ENSG00000163319	homo_sapiens	ENSP00000295491	90.1408	84.507	vulpes_vulpes	ENSVVUP00000021314	89.5105	83.9161
ENSG00000163319	homo_sapiens	ENSP00000295491	73.2394	65.493	mus_spretus	MGP_SPRETEiJ_P0071998	80	71.5385
ENSG00000163319	homo_sapiens	ENSP00000295491	83.0986	75.3521	equus_asinus	ENSEASP00005046501	52.2124	47.3451
ENSG00000163319	homo_sapiens	ENSP00000295491	60.5634	54.2254	capra_hircus	ENSCHIP00000016201	81.9048	73.3333
ENSG00000163319	homo_sapiens	ENSP00000295491	82.3944	76.7606	capra_hircus	ENSCHIP00000002047	81.8182	76.2238
ENSG00000163319	homo_sapiens	ENSP00000295491	73.9437	65.493	capra_hircus	ENSCHIP00000020019	76.6423	67.8832
ENSG00000163319	homo_sapiens	ENSP00000295491	79.5775	73.2394	capra_hircus	ENSCHIP00000026373	91.129	83.871
ENSG00000163319	homo_sapiens	ENSP00000295491	59.8592	52.1127	capra_hircus	ENSCHIP00000020834	80.1887	69.8113
ENSG00000163319	homo_sapiens	ENSP00000295491	92.2535	85.9155	loxodonta_africana	ENSLAFP00000000889	90.9722	84.7222
ENSG00000163319	homo_sapiens	ENSP00000295491	89.4366	85.2113	panthera_leo	ENSPLOP00000013679	88.8112	84.6154
ENSG00000163319	homo_sapiens	ENSP00000295491	91.5493	87.3239	ailuropoda_melanoleuca	ENSAMEP00000026511	71.8232	68.5083
ENSG00000163319	homo_sapiens	ENSP00000295491	86.6197	78.8732	bos_indicus_hybrid	ENSBIXP00005038486	86.014	78.3217
ENSG00000163319	homo_sapiens	ENSP00000295491	89.4366	82.3944	bos_indicus_hybrid	ENSBIXP00005015248	85.8108	79.0541
ENSG00000163319	homo_sapiens	ENSP00000295491	85.2113	78.169	bos_indicus_hybrid	ENSBIXP00005044376	84.0278	77.0833
ENSG00000163319	homo_sapiens	ENSP00000295491	63.3803	57.7465	bos_indicus_hybrid	ENSBIXP00005016629	86.5385	78.8462
ENSG00000163319	homo_sapiens	ENSP00000295491	69.0141	64.0845	oryctolagus_cuniculus	ENSOCUP00000030431	88.2883	81.982
ENSG00000163319	homo_sapiens	ENSP00000295491	91.5493	86.6197	oryctolagus_cuniculus	ENSOCUP00000046679	90.2778	85.4167
ENSG00000163319	homo_sapiens	ENSP00000295491	91.5493	88.0282	equus_caballus	ENSECAP00000017828	73.4463	70.6215
ENSG00000163319	homo_sapiens	ENSP00000295491	90.1408	84.507	canis_lupus_familiaris	ENSCAFP00845029920	89.5105	83.9161
ENSG00000163319	homo_sapiens	ENSP00000295491	89.4366	85.2113	panthera_pardus	ENSPPRP00000019851	88.8112	84.6154
ENSG00000163319	homo_sapiens	ENSP00000295491	90.1408	84.507	marmota_marmota_marmota	ENSMMMP00000005216	89.5105	83.9161
ENSG00000163319	homo_sapiens	ENSP00000295491	92.2535	86.6197	balaenoptera_musculus	ENSBMSP00010003459	90.9722	85.4167
ENSG00000163319	homo_sapiens	ENSP00000295491	92.9577	84.507	cavia_porcellus	ENSCPOP00000008258	91.6667	83.3333
ENSG00000163319	homo_sapiens	ENSP00000295491	89.4366	84.507	felis_catus	ENSFCAP00000040372	88.8112	83.9161
ENSG00000163319	homo_sapiens	ENSP00000295491	92.2535	88.7324	ursus_americanus	ENSUAMP00000016160	91.6084	88.1119
ENSG00000163319	homo_sapiens	ENSP00000295491	80.9859	73.2394	monodelphis_domestica	ENSMODP00000057868	72.327	65.4088
ENSG00000163319	homo_sapiens	ENSP00000295491	86.6197	78.8732	bison_bison_bison	ENSBBBP00000016550	86.014	78.3217
ENSG00000163319	homo_sapiens	ENSP00000295491	89.4366	83.0986	bison_bison_bison	ENSBBBP00000026052	88.8112	82.5175
ENSG00000163319	homo_sapiens	ENSP00000295491	73.2394	69.0141	monodon_monoceros	ENSMMNP00015027701	88.8889	83.7607
ENSG00000163319	homo_sapiens	ENSP00000295491	90.8451	85.9155	monodon_monoceros	ENSMMNP00015029424	90.2098	85.3147
ENSG00000163319	homo_sapiens	ENSP00000295491	90.8451	85.2113	sus_scrofa	ENSSSCP00000040839	90.2098	84.6154
ENSG00000163319	homo_sapiens	ENSP00000295491	71.831	66.1972	microcebus_murinus	ENSMICP00000023294	87.1795	80.3419
ENSG00000163319	homo_sapiens	ENSP00000295491	90.1408	85.2113	microcebus_murinus	ENSMICP00000029337	88.8889	84.0278
ENSG00000163319	homo_sapiens	ENSP00000295491	91.5493	83.0986	octodon_degus	ENSODEP00000010163	89.0411	80.8219
ENSG00000163319	homo_sapiens	ENSP00000295491	91.5493	83.8028	octodon_degus	ENSODEP00000026859	90.2778	82.6389
ENSG00000163319	homo_sapiens	ENSP00000295491	58.4507	57.0423	jaculus_jaculus	ENSJJAP00000022357	85.567	83.5052
ENSG00000163319	homo_sapiens	ENSP00000295491	90.1408	83.8028	ovis_aries_rambouillet	ENSOARP00020018606	89.5105	83.2168
ENSG00000163319	homo_sapiens	ENSP00000295491	92.2535	88.7324	ursus_maritimus	ENSUMAP00000011792	91.6084	88.1119
ENSG00000163319	homo_sapiens	ENSP00000295491	57.7465	54.2254	ochotona_princeps	ENSOPRP00000003783	58.5714	55
ENSG00000163319	homo_sapiens	ENSP00000295491	91.5493	86.6197	delphinapterus_leucas	ENSDLEP00000020041	90.9091	86.014
ENSG00000163319	homo_sapiens	ENSP00000295491	66.9014	63.3803	delphinapterus_leucas	ENSDLEP00000027524	88.785	84.1122
ENSG00000163319	homo_sapiens	ENSP00000295491	92.9577	88.0282	physeter_catodon	ENSPCTP00005014962	91.6667	86.8056
ENSG00000163319	homo_sapiens	ENSP00000295491	87.3239	80.2817	mus_caroli	MGP_CAROLIEiJ_P0069337	86.7133	79.7203
ENSG00000163319	homo_sapiens	ENSP00000295491	87.3239	79.5775	mus_musculus	ENSMUSP00000016977	86.7133	79.021
ENSG00000163319	homo_sapiens	ENSP00000295491	87.3239	83.0986	dipodomys_ordii	ENSDORP00000011990	87.3239	83.0986
ENSG00000163319	homo_sapiens	ENSP00000295491	64.7887	61.9718	aotus_nancymaae	ENSANAP00000036056	82.1429	78.5714
ENSG00000163319	homo_sapiens	ENSP00000295491	91.5493	85.2113	saimiri_boliviensis_boliviensis	ENSSBOP00000010736	84.4156	78.5714
ENSG00000163319	homo_sapiens	ENSP00000295491	90.1408	83.0986	vicugna_pacos	ENSVPAP00000010577	89.5105	82.5175
ENSG00000163319	homo_sapiens	ENSP00000295491	90.1408	83.8028	tupaia_belangeri	ENSTBEP00000010828	88.8889	82.6389
ENSG00000163319	homo_sapiens	ENSP00000295491	90.1408	84.507	phocoena_sinus	ENSPSNP00000004183	89.5105	83.9161
ENSG00000163319	homo_sapiens	ENSP00000295491	73.2394	69.0141	phocoena_sinus	ENSPSNP00000030232	89.6552	84.4828
ENSG00000163319	homo_sapiens	ENSP00000295491	90.1408	83.8028	camelus_dromedarius	ENSCDRP00005006270	89.5105	83.2168
ENSG00000163319	homo_sapiens	ENSP00000295491	90.8451	86.6197	carlito_syrichta	ENSTSYP00000023030	90.2098	86.014
ENSG00000163319	homo_sapiens	ENSP00000295491	88.7324	84.507	panthera_tigris_altaica	ENSPTIP00000025498	88.1119	83.9161
ENSG00000163319	homo_sapiens	ENSP00000295491	83.8028	77.4648	rattus_norvegicus	ENSRNOP00000081962	69.5906	64.3275
ENSG00000163319	homo_sapiens	ENSP00000295491	92.9577	87.3239	prolemur_simus	ENSPSMP00000025889	91.6667	86.1111
ENSG00000163319	homo_sapiens	ENSP00000295491	85.2113	79.5775	microtus_ochrogaster	ENSMOCP00000009703	85.8156	80.1418
ENSG00000163319	homo_sapiens	ENSP00000295491	85.9155	80.9859	microtus_ochrogaster	ENSMOCP00000016793	86.5248	81.5603
ENSG00000163319	homo_sapiens	ENSP00000295491	88.0282	83.8028	peromyscus_maniculatus_bairdii	ENSPEMP00000006060	86.2069	82.069
ENSG00000163319	homo_sapiens	ENSP00000295491	86.6197	78.8732	bos_mutus	ENSBMUP00000014841	86.014	78.3217
ENSG00000163319	homo_sapiens	ENSP00000295491	89.4366	82.3944	bos_mutus	ENSBMUP00000005439	88.8112	81.8182
ENSG00000163319	homo_sapiens	ENSP00000295491	66.1972	59.1549	mus_spicilegus	ENSMSIP00000020950	69.6296	62.2222
ENSG00000163319	homo_sapiens	ENSP00000295491	71.831	61.2676	mus_spicilegus	ENSMSIP00000037712	75	63.9706
ENSG00000163319	homo_sapiens	ENSP00000295491	88.0282	81.6901	mus_spicilegus	ENSMSIP00000001959	87.4126	81.1189
ENSG00000163319	homo_sapiens	ENSP00000295491	87.3239	83.8028	cricetulus_griseus_chok1gshd	ENSCGRP00001000090	87.9433	84.3972
ENSG00000163319	homo_sapiens	ENSP00000295491	59.1549	54.2254	pteropus_vampyrus	ENSPVAP00000006083	85.7143	78.5714
ENSG00000163319	homo_sapiens	ENSP00000295491	88.7324	79.5775	myotis_lucifugus	ENSMLUP00000015555	88.1119	79.021
ENSG00000163319	homo_sapiens	ENSP00000295491	54.9296	47.8873	vombatus_ursinus	ENSVURP00010021322	68.4211	59.6491
ENSG00000163319	homo_sapiens	ENSP00000295491	54.9296	47.8873	vombatus_ursinus	ENSVURP00010021314	68.4211	59.6491
ENSG00000163319	homo_sapiens	ENSP00000295491	78.8732	70.4225	vombatus_ursinus	ENSVURP00010008429	80.5755	71.9424
ENSG00000163319	homo_sapiens	ENSP00000295491	83.0986	76.7606	rhinolophus_ferrumequinum	ENSRFEP00010019377	82.5175	76.2238
ENSG00000163319	homo_sapiens	ENSP00000295491	88.7324	84.507	rhinolophus_ferrumequinum	ENSRFEP00010003901	88.1119	83.9161
ENSG00000163319	homo_sapiens	ENSP00000295491	86.6197	78.8732	neovison_vison	ENSNVIP00000005033	86.014	78.3217
ENSG00000163319	homo_sapiens	ENSP00000295491	89.4366	82.3944	bos_taurus	ENSBTAP00000024161	88.8112	81.8182
ENSG00000163319	homo_sapiens	ENSP00000295491	63.3803	57.7465	bos_taurus	ENSBTAP00000072063	86.5385	78.8462
ENSG00000163319	homo_sapiens	ENSP00000295491	78.8732	71.831	heterocephalus_glaber_female	ENSHGLP00000041393	82.963	75.5556
ENSG00000163319	homo_sapiens	ENSP00000295491	92.2535	83.0986	heterocephalus_glaber_female	ENSHGLP00000041324	63.9024	57.561
ENSG00000163319	homo_sapiens	ENSP00000295491	98.5916	96.4789	rhinopithecus_bieti	ENSRBIP00000036121	97.2222	95.1389
ENSG00000163319	homo_sapiens	ENSP00000295491	90.1408	83.8028	canis_lupus_dingo	ENSCAFP00020013041	89.5105	83.2168
ENSG00000163319	homo_sapiens	ENSP00000295491	82.3944	74.6479	sciurus_vulgaris	ENSSVLP00005022128	85.4015	77.3723
ENSG00000163319	homo_sapiens	ENSP00000295491	92.2535	86.6197	sciurus_vulgaris	ENSSVLP00005025072	91.6084	86.014
ENSG00000163319	homo_sapiens	ENSP00000295491	79.5775	72.5352	phascolarctos_cinereus	ENSPCIP00000006375	82.4818	75.1825
ENSG00000163319	homo_sapiens	ENSP00000295491	71.1268	59.1549	phascolarctos_cinereus	ENSPCIP00000000180	74.2647	61.7647
ENSG00000163319	homo_sapiens	ENSP00000295491	70.4225	62.6761	phascolarctos_cinereus	ENSPCIP00000026308	70.922	63.1206
ENSG00000163319	homo_sapiens	ENSP00000295491	88.7324	81.6901	procavia_capensis	ENSPCAP00000004633	87.5	80.5556
ENSG00000163319	homo_sapiens	ENSP00000295491	85.2113	83.0986	nannospalax_galili	ENSNGAP00000014760	86.4286	84.2857
ENSG00000163319	homo_sapiens	ENSP00000295491	89.4366	82.3944	bos_grunniens	ENSBGRP00000033564	88.8112	81.8182
ENSG00000163319	homo_sapiens	ENSP00000295491	92.9577	85.2113	chinchilla_lanigera	ENSCLAP00000025323	91.6667	84.0278
ENSG00000163319	homo_sapiens	ENSP00000295491	92.2535	84.507	chinchilla_lanigera	ENSCLAP00000011895	89.726	82.1918
ENSG00000163319	homo_sapiens	ENSP00000295491	64.0845	58.4507	cervus_hanglu_yarkandensis	ENSCHYP00000037875	86.6667	79.0476
ENSG00000163319	homo_sapiens	ENSP00000295491	71.831	64.7887	cervus_hanglu_yarkandensis	ENSCHYP00000028603	88.6957	80
ENSG00000163319	homo_sapiens	ENSP00000295491	74.6479	66.1972	cervus_hanglu_yarkandensis	ENSCHYP00000013905	75.1773	66.6667
ENSG00000163319	homo_sapiens	ENSP00000295491	89.4366	83.8028	catagonus_wagneri	ENSCWAP00000014720	88.1944	82.6389
ENSG00000163319	homo_sapiens	ENSP00000295491	90.8451	85.2113	ictidomys_tridecemlineatus	ENSSTOP00000007146	90.2098	84.6154
ENSG00000163319	homo_sapiens	ENSP00000295491	91.5493	85.2113	urocitellus_parryii	ENSUPAP00010008855	90.9091	84.6154
ENSG00000163319	homo_sapiens	ENSP00000295491	85.2113	78.169	moschus_moschiferus	ENSMMSP00000017206	84.6154	77.6224
ENSG00000163319	homo_sapiens	ENSP00000295491	89.4366	84.507	moschus_moschiferus	ENSMMSP00000031403	88.8112	83.9161
ENSG00000163319	homo_sapiens	ENSP00000295491	90.8451	84.507	moschus_moschiferus	ENSMMSP00000024317	90.2098	83.9161
ENSG00000163319	homo_sapiens	ENSP00000295491	98.5916	96.4789	rhinopithecus_roxellana	ENSRROP00000042375	97.2222	95.1389
ENSG00000163319	homo_sapiens	ENSP00000295491	88.0282	81.6901	mus_pahari	MGP_PahariEiJ_P0032493	87.4126	81.1189
ENSG00000163319	homo_sapiens	ENSP00000295491	90.8451	85.9155	propithecus_coquereli	ENSPCOP00000012171	89.5833	84.7222

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0003735	enables structural constituent of ribosome	2	IBA,NAS	Homo_sapiens(9606)	Function
GO:0005743	located_in mitochondrial inner membrane	2	NAS,TAS	Homo_sapiens(9606)	Component
GO:0005763	part_of mitochondrial small ribosomal subunit	3	IBA,IDA,NAS	Homo_sapiens(9606)	Component
GO:0006412	involved_in translation	2	IBA,NAS	Homo_sapiens(9606)	Process
GO:0032543	involved_in mitochondrial translation	1	NAS	Homo_sapiens(9606)	Process
GO:0070181	enables small ribosomal subunit rRNA binding	1	IBA	Homo_sapiens(9606)	Function