Functions and Diseases

RBP Type Canonical_RBPs
Diseases Cancer
Drug N.A.
Main interacting RNAs rRNA
Moonlighting functions N.A.
Localizations N.A.
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000162910 Gene ID 128308 Accession 16686
Symbol MRPL55 Alias L55nt;bL31m;MRP-L55;AAVG5835;PRO19675 Full Name mitochondrial ribosomal protein L55
Status Confidence Length 2634 bases Strand Minus strand
Position 1 : 228106679 - 228109312 RNA binding domain Mitoc_L55
Summary Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Multiple transcript variants encoding two different isoforms were identified through sequence analysis. [provided by RefSeq, Jul 2008]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000295008 Mitoc_L55 PF09776 3e-57 1
ENSP00000337342 Mitoc_L55 PF09776 3e-57 1
ENSP00000337361 Mitoc_L55 PF09776 3e-57 1
ENSP00000338189 Mitoc_L55 PF09776 3e-57 1
ENSP00000355694 Mitoc_L55 PF09776 3e-57 1
ENSP00000355695 Mitoc_L55 PF09776 3e-57 1
ENSP00000355696 Mitoc_L55 PF09776 3e-57 1
ENSP00000355697 Mitoc_L55 PF09776 3e-57 1
ENSP00000355700 Mitoc_L55 PF09776 3e-57 1
ENSP00000355701 Mitoc_L55 PF09776 3e-57 1
ENSP00000355702 Mitoc_L55 PF09776 3e-57 1
ENSP00000355703 Mitoc_L55 PF09776 3e-57 1
ENSP00000355705 Mitoc_L55 PF09776 3e-57 1
ENSP00000355707 Mitoc_L55 PF09776 3e-57 1
ENSP00000355708 Mitoc_L55 PF09776 3e-57 1
ENSP00000375740 Mitoc_L55 PF09776 3e-57 1
ENSP00000355699 Mitoc_L55 PF09776 6.6e-57 1
ENSP00000403614 Mitoc_L55 PF09776 6.6e-57 1
ENSP00000409966 Mitoc_L55 PF09776 4.1e-31 1
ENSP00000355692 Mitoc_L55 PF09776 4.8e-21 1
ENSP00000355693 Mitoc_L55 PF09776 4.8e-21 1
ENSP00000482290 Mitoc_L55 PF09776 4.8e-21 1
ENSP00000401737 Mitoc_L55 PF09776 1.7e-06 1

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal

Transcripts

Name Transcript ID bp Protein Translation ID
MRPL55-225 ENST00000465268 848 No protein -
MRPL55-223 ENST00000459783 694 55aa ENSP00000482290
MRPL55-206 ENST00000366732 722 55aa ENSP00000355693
MRPL55-207 ENST00000366733 834 128aa ENSP00000355694
MRPL55-208 ENST00000366734 990 128aa ENSP00000355695
MRPL55-209 ENST00000366735 1212 128aa ENSP00000355696
MRPL55-210 ENST00000366736 660 128aa ENSP00000355697
MRPL55-211 ENST00000366738 705 164aa ENSP00000355699
MRPL55-212 ENST00000366739 641 128aa ENSP00000355700
MRPL55-213 ENST00000366740 644 128aa ENSP00000355701
MRPL55-214 ENST00000366741 603 128aa ENSP00000355702
MRPL55-215 ENST00000366742 630 128aa ENSP00000355703
MRPL55-216 ENST00000366744 726 128aa ENSP00000355705
MRPL55-204 ENST00000348259 661 128aa ENSP00000338189
MRPL55-201 ENST00000295008 632 128aa ENSP00000295008
MRPL55-205 ENST00000366731 1423 55aa ENSP00000355692
MRPL55-217 ENST00000366746 565 128aa ENSP00000355707
MRPL55-218 ENST00000366747 603 128aa ENSP00000355708
MRPL55-202 ENST00000336300 722 128aa ENSP00000337361
MRPL55-221 ENST00000430433 864 164aa ENSP00000403614
MRPL55-203 ENST00000336520 738 128aa ENSP00000337342
MRPL55-219 ENST00000391867 665 128aa ENSP00000375740
MRPL55-222 ENST00000457264 544 76aa ENSP00000409966
MRPL55-220 ENST00000411464 767 43aa ENSP00000401737
MRPL55-234 ENST00000497758 470 No protein -
MRPL55-224 ENST00000464148 636 24aa ENSP00000484813
MRPL55-227 ENST00000475832 858 No protein -
MRPL55-226 ENST00000473066 820 No protein -
MRPL55-231 ENST00000492170 241 No protein -
MRPL55-228 ENST00000476267 169 No protein -
MRPL55-232 ENST00000495434 224 8aa ENSP00000479463
MRPL55-229 ENST00000483159 790 4aa ENSP00000479251
MRPL55-233 ENST00000495899 790 No protein -
MRPL55-230 ENST00000489430 847 No protein -

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000162910

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000162910homo_sapiensENSP0000033734296.87596.0938nomascus_leucogenysENSNLEP0000001728175.609875
ENSG00000162910homo_sapiensENSP0000033734298.437598.4375pan_paniscusENSPPAP0000001478176.829376.8293
ENSG00000162910homo_sapiensENSP0000033734297.656296.0938pongo_abeliiENSPPYP0000000014476.687175.4601
ENSG00000162910homo_sapiensENSP0000033734297.656297.6562pan_troglodytesENSPTRP0000000349576.219576.2195
ENSG00000162910homo_sapiensENSP0000033734297.656297.6562gorilla_gorillaENSGGOP0000001532576.219576.2195
ENSG00000162910homo_sapiensENSP0000033734274.218858.5938sarcophilus_harrisiiENSSHAP0000003655975.396859.5238
ENSG00000162910homo_sapiensENSP0000033734277.343866.4062dasypus_novemcinctusENSDNOP0000001594379.268
ENSG00000162910homo_sapiensENSP0000033734289.843885.9375callithrix_jacchusENSCJAP0000003078672.32769.1824
ENSG00000162910homo_sapiensENSP0000033734294.531292.1875cercocebus_atysENSCATP0000000031280.132578.1457
ENSG00000162910homo_sapiensENSP0000033734294.531291.4062macaca_fascicularisENSMFAP0000005071674.233171.7791
ENSG00000162910homo_sapiensENSP0000033734294.531291.4062macaca_nemestrinaENSMNEP0000002588485.815682.9787
ENSG00000162910homo_sapiensENSP0000033734294.531291.4062papio_anubisENSPANP0000001118474.233171.7791
ENSG00000162910homo_sapiensENSP0000033734294.531292.1875mandrillus_leucophaeusENSMLEP0000003872277.070175.1592
ENSG00000162910homo_sapiensENSP0000033734277.343870.3125mus_spretusMGP_SPRETEiJ_P002827773.880667.1642
ENSG00000162910homo_sapiensENSP0000033734278.12571.0938equus_asinusENSEASP000050559818072.8
ENSG00000162910homo_sapiensENSP0000033734276.562564.8438capra_hircusENSCHIP0000002876177.777865.873
ENSG00000162910homo_sapiensENSP000003373427564.0625loxodonta_africanaENSLAFP0000000250876.190565.0794
ENSG00000162910homo_sapiensENSP0000033734277.343871.0938panthera_leoENSPLOP0000000002173.333367.4074
ENSG00000162910homo_sapiensENSP0000033734252.343842.1875ailuropoda_melanoleucaENSAMEP0000003059954.91844.2623
ENSG00000162910homo_sapiensENSP0000033734278.12568.75ailuropoda_melanoleucaENSAMEP0000001720179.365169.8413
ENSG00000162910homo_sapiensENSP0000033734278.12566.4062bos_indicus_hybridENSBIXP0000500540971.428660.7143
ENSG00000162910homo_sapiensENSP0000033734278.906268.75oryctolagus_cuniculusENSOCUP0000001321280.870.4
ENSG00000162910homo_sapiensENSP0000033734281.2571.0938canis_lupus_familiarisENSCAFP0084501069683.87173.3871
ENSG00000162910homo_sapiensENSP0000033734277.343871.0938panthera_pardusENSPPRP0000001040678.571472.2222
ENSG00000162910homo_sapiensENSP0000033734283.593875.7812marmota_marmota_marmotaENSMMMP0000001976184.25276.378
ENSG00000162910homo_sapiensENSP0000033734260.156249.2188balaenoptera_musculusENSBMSP0001001197035.81429.3023
ENSG00000162910homo_sapiensENSP0000033734282.031275.7812cavia_porcellusENSCPOP0000001283182.031275.7812
ENSG00000162910homo_sapiensENSP0000033734277.343870.3125felis_catusENSFCAP0000001409978.571471.4286
ENSG00000162910homo_sapiensENSP0000033734249.218838.2812ursus_americanusENSUAMP0000002965340.909131.8182
ENSG00000162910homo_sapiensENSP0000033734277.343867.9688ursus_americanusENSUAMP0000002091878.571469.0476
ENSG00000162910homo_sapiensENSP0000033734271.87554.6875monodelphis_domesticaENSMODP0000001724475.409857.377
ENSG00000162910homo_sapiensENSP0000033734276.562565.625bison_bison_bisonENSBBBP0000000819879.032367.7419
ENSG00000162910homo_sapiensENSP0000033734277.343865.625monodon_monocerosENSMMNP0001500472978.571466.6667
ENSG00000162910homo_sapiensENSP0000033734278.12567.9688sus_scrofaENSSSCP0000002070279.365169.0476
ENSG00000162910homo_sapiensENSP0000033734288.281285.9375microcebus_murinusENSMICP0000003405088.281285.9375
ENSG00000162910homo_sapiensENSP0000033734275.781271.875octodon_degusENSODEP0000000135281.512677.3109
ENSG00000162910homo_sapiensENSP0000033734281.2572.6562jaculus_jaculusENSJJAP0000002052481.889873.2283
ENSG00000162910homo_sapiensENSP0000033734275.781265.625ovis_aries_rambouilletENSOARP0002002356078.225867.7419
ENSG00000162910homo_sapiensENSP0000033734277.343867.1875ursus_maritimusENSUMAP0000000087478.571468.254
ENSG00000162910homo_sapiensENSP0000033734275.781264.0625ochotona_princepsENSOPRP0000001377765.540555.4054
ENSG00000162910homo_sapiensENSP0000033734276.562563.2812delphinapterus_leucasENSDLEP0000001652477.165463.7795
ENSG00000162910homo_sapiensENSP0000033734278.12567.1875physeter_catodonENSPCTP0000500243150.505143.4343
ENSG00000162910homo_sapiensENSP0000033734278.906270.3125mus_caroliMGP_CAROLIEiJ_P002690675.373167.1642
ENSG00000162910homo_sapiensENSP0000033734278.12571.0938mus_musculusENSMUSP0000010441474.626967.9104
ENSG00000162910homo_sapiensENSP0000033734282.031271.0938mustela_putorius_furoENSMPUP0000000099783.333372.2222
ENSG00000162910homo_sapiensENSP0000033734288.281283.5938aotus_nancymaaeENSANAP0000003828571.974568.1529
ENSG00000162910homo_sapiensENSP0000033734290.62584.375saimiri_boliviensis_boliviensisENSSBOP0000003865676.821271.5232
ENSG00000162910homo_sapiensENSP0000033734294.531291.4062chlorocebus_sabaeusENSCSAP0000001253494.531291.4062
ENSG00000162910homo_sapiensENSP0000033734278.12571.0938mesocricetus_auratusENSMAUP0000000039678.740271.6535
ENSG00000162910homo_sapiensENSP0000033734277.343866.4062phocoena_sinusENSPSNP0000001031678.571467.4603
ENSG00000162910homo_sapiensENSP0000033734278.12570.3125camelus_dromedariusENSCDRP0000500990278.740270.8661
ENSG00000162910homo_sapiensENSP0000033734283.593877.3438carlito_syrichtaENSTSYP0000000268283.593877.3438
ENSG00000162910homo_sapiensENSP0000033734277.343871.0938panthera_tigris_altaicaENSPTIP0000000701673.333367.4074
ENSG00000162910homo_sapiensENSP0000033734260.156249.2188rattus_norvegicusENSRNOP0000007639655.797145.6522
ENSG00000162910homo_sapiensENSP0000033734289.843885.1562prolemur_simusENSPSMP0000001873989.843885.1562
ENSG00000162910homo_sapiensENSP0000033734280.468871.875microtus_ochrogasterENSMOCP0000002660276.865768.6567
ENSG00000162910homo_sapiensENSP0000033734282.031272.6562peromyscus_maniculatus_bairdiiENSPEMP0000000890378.358269.403
ENSG00000162910homo_sapiensENSP0000033734276.562565.625bos_mutusENSBMUP0000001765379.032367.7419
ENSG00000162910homo_sapiensENSP0000033734277.343869.5312mus_spicilegusENSMSIP0000002505173.880666.4179
ENSG00000162910homo_sapiensENSP0000033734281.2572.6562cricetulus_griseus_chok1gshdENSCGRP0000102175481.889873.2283
ENSG00000162910homo_sapiensENSP000003373427565.625myotis_lucifugusENSMLUP0000001957675.590666.1417
ENSG00000162910homo_sapiensENSP0000033734271.87554.6875vombatus_ursinusENSVURP0001000466773.015955.5556
ENSG00000162910homo_sapiensENSP0000033734271.87554.6875vombatus_ursinusENSVURP0001000251673.015955.5556
ENSG00000162910homo_sapiensENSP000003373427557.0312vombatus_ursinusENSVURP0001001434276.190557.9365
ENSG00000162910homo_sapiensENSP0000033734280.468872.6562rhinolophus_ferrumequinumENSRFEP0001003085883.064575
ENSG00000162910homo_sapiensENSP0000033734282.031271.875neovison_visonENSNVIP0000000111683.333373.0159
ENSG00000162910homo_sapiensENSP0000033734278.12566.4062bos_taurusENSBTAP0000002761471.428660.7143
ENSG00000162910homo_sapiensENSP0000033734281.2573.4375heterocephalus_glaber_femaleENSHGLP0000004933381.889874.0157
ENSG00000162910homo_sapiensENSP0000033734294.531292.1875rhinopithecus_bietiENSRBIP0000002859277.070175.1592
ENSG00000162910homo_sapiensENSP0000033734281.2571.0938canis_lupus_dingoENSCAFP0002000707483.87173.3871
ENSG00000162910homo_sapiensENSP0000033734282.812576.5625sciurus_vulgarisENSSVLP0000500531383.464677.1654
ENSG00000162910homo_sapiensENSP000003373427565.625procavia_capensisENSPCAP000000098546052.5
ENSG00000162910homo_sapiensENSP0000033734278.12568.75nannospalax_galiliENSNGAP0000002615878.12568.75
ENSG00000162910homo_sapiensENSP0000033734276.562565.625bos_grunniensENSBGRP0000000506379.032367.7419
ENSG00000162910homo_sapiensENSP0000033734285.937578.125chinchilla_lanigeraENSCLAP0000000120685.937578.125
ENSG00000162910homo_sapiensENSP0000033734277.343867.9688cervus_hanglu_yarkandensisENSCHYP0000001549479.269.6
ENSG00000162910homo_sapiensENSP0000033734278.906268.75catagonus_wagneriENSCWAP0000002727180.158769.8413
ENSG00000162910homo_sapiensENSP0000033734282.031277.3438otolemur_garnettiiENSOGAP0000000982982.677277.9528
ENSG00000162910homo_sapiensENSP0000033734289.843886.7188cebus_imitatorENSCCAP0000002777971.87569.375
ENSG00000162910homo_sapiensENSP0000033734285.156275.7812urocitellus_parryiiENSUPAP0001001184185.826876.378
ENSG00000162910homo_sapiensENSP0000033734275.781266.4062moschus_moschiferusENSMMSP0000003013076.984167.4603
ENSG00000162910homo_sapiensENSP0000033734294.531292.1875rhinopithecus_roxellanaENSRROP0000001970777.070175.1592
ENSG00000162910homo_sapiensENSP0000033734277.343869.5312mus_pahariMGP_PahariEiJ_P003367073.880666.4179
ENSG00000162910homo_sapiensENSP0000033734287.583.5938propithecus_coquereliENSPCOP0000000569587.583.5938

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0003735enables structural constituent of ribosome2IBA,ISSHomo_sapiens(9606)Function
GO:0005739located_in mitochondrion1IDAHomo_sapiens(9606)Component
GO:0005743located_in mitochondrial inner membrane2NAS,TASHomo_sapiens(9606)Component
GO:0005762part_of mitochondrial large ribosomal subunit4IBA,IDA,ISS,NASHomo_sapiens(9606)Component
GO:0006412involved_in translation2IBA,ISSHomo_sapiens(9606)Process
GO:0032543involved_in mitochondrial translation1NASHomo_sapiens(9606)Process
GO:0045202located_in synapse1IEAHomo_sapiens(9606)Component

Expression