RBPWorld - a comprehensive database of RNA Binding Proteins

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Functions and Diseases

RBP Type	Canonical_RBPs
Diseases	N.A.
Drug	N.A.
Main interacting RNAs	N.A.
Moonlighting functions	Metabolic enzyme
Localizations	N.A.
BulkPerturb-seq

Description

Ensembl ID	ENSG00000161920	Gene ID	400569	Accession	32687
Symbol	MED11	Alias	NDDRSB;HSPC296	Full Name	mediator complex subunit 11
Status	Confidence	Length	2181 bases	Strand	Plus strand
Position	17 : 4731428 - 4733608	RNA binding domain	Med11
Summary	MED11 is a component of the Mediator complex, which is a coactivator for DNA-binding factors that activate transcription via RNA polymerase II (Sato et al., 2003 [PubMed 12584197]).[supplied by OMIM, Oct 2008]

RNA binding domains (RBDs)

Protein	Domain	Pfam ID	E-value	Domain number
ENSP00000293777	Med11	PF10280	1.9e-12	1
ENSP00000459834	Med11	PF10280	3.5e-11	1
ENSP00000460400	Med11	PF10280	4.6e-10	1

RNA binding proteomes (RBPomes)

Pubmed ID	Full Name	Cell	Author	Time	Doi

Literatures on RNA binding capacity

Pubmed ID	Title	Author	Time	Journal

Transcripts

Name	Transcript ID	bp	Protein	Translation ID
MED11-203	ENST00000575284	652	85aa	ENSP00000460400
MED11-201	ENST00000293777	836	117aa	ENSP00000293777
MED11-204	ENST00000674339	706	35aa	ENSP00000501539
MED11-202	ENST00000573708	802	93aa	ENSP00000459834

Gene Model

Click here to download ENSG00000161920's gene model file

Pathways

Pathway ID	Pathway Name	Source

Phenotypes

ensgID	Trait	pValue	Pubmed ID
27822	Blood Glucose	6.5540000E-005	-

GWAS

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Protein-Protein Interaction (PPI)

Click here to download ENSG00000161920's PPI file

Paralogs

Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Orthologs

Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Gene Ontology

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0000151	part_of ubiquitin ligase complex	1	IEA	Homo_sapiens(9606)	Component
GO:0003712	enables transcription coregulator activity	1	IEA	Homo_sapiens(9606)	Function
GO:0005515	enables protein binding	1	IPI	Homo_sapiens(9606)	Function
GO:0005634	located_in nucleus	1	IDA	Homo_sapiens(9606)	Component
GO:0016567	involved_in protein ubiquitination	1	IEA	Homo_sapiens(9606)	Process
GO:0016592	part_of mediator complex	2	IBA,IDA	Homo_sapiens(9606)	Component
GO:0032968	involved_in positive regulation of transcription elongation by RNA polymerase II	1	NAS	Homo_sapiens(9606)	Process
GO:0051123	involved_in RNA polymerase II preinitiation complex assembly	1	NAS	Homo_sapiens(9606)	Process
GO:0060261	involved_in positive regulation of transcription initiation by RNA polymerase II	1	NAS	Homo_sapiens(9606)	Process
GO:0061630	enables ubiquitin protein ligase activity	1	IEA	Homo_sapiens(9606)	Function
GO:0070847	part_of core mediator complex	1	IPI	Homo_sapiens(9606)	Component

Expression