RBPWorld - a comprehensive database of RNA Binding Proteins

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RBP World!

Functions and Diseases

RBP Type	Non-canonical_RBPs
Diseases	Disease
Drug	N.A.
Main interacting RNAs	N.A.
Moonlighting functions	N.A.
Localizations	Nucleoli
BulkPerturb-seq

Description

Ensembl ID	ENSG00000161888	Gene ID	147841	Accession	26913
Symbol	SPC24	Alias	SPBC24	Full Name	SPC24 component of NDC80 kinetochore complex
Status	Confidence	Length	24288 bases	Strand	Minus strand
Position	19 : 11131520 - 11155807	RNA binding domain	N.A.
Summary	Predicted to be involved in cell division. Located in nucleolus and nucleoplasm. Part of Ndc80 complex. [provided by Alliance of Genome Resources, Apr 2022]

RNA binding domains (RBDs)

Protein	Domain	Pfam ID	E-value	Domain number

RNA binding proteomes (RBPomes)

Pubmed ID	Full Name	Cell	Author	Time	Doi

Literatures on RNA binding capacity

Pubmed ID	Title	Author	Time	Journal

Transcripts

Name	Transcript ID	bp	Protein	Translation ID
SPC24-203	ENST00000585567	633	209aa	ENSP00000468818
SPC24-206	ENST00000592540	2290	197aa	ENSP00000465075
SPC24-205	ENST00000591396	832	171aa	ENSP00000466688
SPC24-207	ENST00000592967	833	172aa	ENSP00000465335
SPC24-201	ENST00000423327	840	134aa	ENSP00000397131
SPC24-204	ENST00000586708	378	126aa	ENSP00000468366
SPC24-202	ENST00000585486	699	168aa	ENSP00000465167

Gene Model

Click here to download ENSG00000161888's gene model file

Pathways

Pathway ID	Pathway Name	Source

Phenotypes

ensgID	Trait	pValue	Pubmed ID
15083	Myocardial Infarction	1.3190834E-004	-
56833	Carcinoma, Non-Small-Cell Lung	5.2810000E-005	-
59753	Blood Pressure	1.7158889E-005	-
60129	Arterial Pressure	5.6791850E-006	-

GWAS

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Protein-Protein Interaction (PPI)

Click here to download ENSG00000161888's PPI file

Paralogs

Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Orthologs

Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Gene Ontology

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0000776	located_in kinetochore	1	IDA	Homo_sapiens(9606)	Component
GO:0005515	enables protein binding	1	IPI	Homo_sapiens(9606)	Function
GO:0005654	located_in nucleoplasm	1	IDA	Homo_sapiens(9606)	Component
GO:0005730	located_in nucleolus	1	IDA	Homo_sapiens(9606)	Component
GO:0005829	located_in cytosol	1	TAS	Homo_sapiens(9606)	Component
GO:0007059	involved_in chromosome segregation	2	IBA,NAS	Homo_sapiens(9606)	Process
GO:0007094	involved_in mitotic spindle assembly checkpoint signaling	1	NAS	Homo_sapiens(9606)	Process
GO:0008017	contributes_to microtubule binding	1	IBA	Homo_sapiens(9606)	Function
GO:0008608	involved_in attachment of spindle microtubules to kinetochore	1	IDA	Homo_sapiens(9606)	Process
GO:0031262	part_of Ndc80 complex	3	IBA,IDA,IPI	Homo_sapiens(9606)	Component
GO:0051301	involved_in cell division	1	IEA	Homo_sapiens(9606)	Process

Expression