RBP Type
Canonical_RBPs
Diseases
N.A.
Drug
N.A.
Main interacting RNAs
mRNA
Moonlighting functions
N.A.
Localizations
N.A.
BulkPerturb-seq
N.A.
Ensembl ID ENSG00000161265 Gene ID
199746 Accession
23020
Symbol
U2AF1L4
Alias
U2af26;U2AF1L3;U2AF1RS3;U2AF1-RS3;U2AF1L3V1
Full Name
U2 small nuclear RNA auxiliary factor 1 like 4
Status
Confidence
Length
2982 bases
Strand
Minus strand
Position
19 : 35742464 - 35745445
RNA binding domain
zf-CCCH , RRM_1
Summary
Predicted to enable pre-mRNA 3'-splice site binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be located in nucleoplasm. Predicted to be part of U2AF complex and spliceosomal complex. [provided by Alliance of Genome Resources, Apr 2022]
RNA binding domains (RBDs)
Protein
Domain
Pfam ID
E-value
Domain number
ENSP00000368258
RRM_1
PF00076 0.00014
1
ENSP00000368258
zf-CCCH
PF00642 6.6e-13
2
ENSP00000368258
zf-CCCH
PF00642 6.6e-13
3
ENSP00000292879
RRM_1
PF00076 0.00018
1
ENSP00000292879
zf-CCCH
PF00642 2.1e-06
2
ENSP00000397645
RRM_1
PF00076 0.0005
1
ENSP00000397645
zf-CCCH
PF00642 1e-12
2
ENSP00000397645
zf-CCCH
PF00642 1e-12
3
ENSP00000469891
zf-CCCH
PF00642 4.2e-07
1
RNA binding proteomes (RBPomes)
Pubmed ID
Full Name
Cell
Author
Time
Doi
Literatures on RNA binding capacity
Pubmed ID
Title
Author
Time
Journal
Name
Transcript ID
bp
Protein
Translation ID
U2AF1L4-215
ENST00000591057
561
51aa
ENSP00000465242
U2AF1L4-216
ENST00000591084
723
40aa
ENSP00000475046
U2AF1L4-202
ENST00000378975
765
181aa
ENSP00000368258
U2AF1L4-213
ENST00000590135
1763
No protein
-
U2AF1L4-204
ENST00000585554
1244
No protein
-
U2AF1L4-203
ENST00000412391
904
220aa
ENSP00000397645
U2AF1L4-217
ENST00000591855
744
No protein
-
U2AF1L4-219
ENST00000594792
702
33aa
ENSP00000471804
U2AF1L4-220
ENST00000600296
525
71aa
ENSP00000474493
U2AF1L4-208
ENST00000587987
1036
39aa
ENSP00000465170
U2AF1L4-212
ENST00000589429
525
36aa
ENSP00000473940
U2AF1L4-211
ENST00000588980
2018
No protein
-
U2AF1L4-218
ENST00000592913
975
No protein
-
U2AF1L4-201
ENST00000292879
729
202aa
ENSP00000292879
U2AF1L4-210
ENST00000588892
2582
No protein
-
U2AF1L4-206
ENST00000586476
1930
No protein
-
U2AF1L4-221
ENST00000601236
455
66aa
ENSP00000469891
U2AF1L4-205
ENST00000585771
572
No protein
-
U2AF1L4-207
ENST00000587886
263
10aa
ENSP00000467441
U2AF1L4-209
ENST00000588100
476
No protein
-
U2AF1L4-214
ENST00000590650
416
No protein
-
Pathway ID
Pathway Name
Source
ensgID
Trait
pValue
Pubmed ID
ensgID SNP Chromosome Position
Trait PubmedID Or or BEAT
EFO ID
Protein-Protein Interaction (PPI)
Ensembl ID
Source
Target
Species
Protein ID
Perc_pos
Perc_id
Species
Protein ID
Perc_pos
Perc_id
ENSG00000161265 homo_sapiens ENSP00000291552 65.8333 59.5833 homo_sapiens ENSP00000368258 87.2928 79.0055 ENSG00000161265 homo_sapiens ENSP00000303015 20.5394 14.5228 homo_sapiens ENSP00000368258 54.6961 38.674
Ensembl ID
Source
Target
Species
Protein ID
Perc_pos
Perc_id
Species
Protein ID
Perc_pos
Perc_id
ENSG00000161265 homo_sapiens ENSP00000368258 94.4751 93.9227 nomascus_leucogenys ENSNLEP00000029922 77.7273 77.2727 ENSG00000161265 homo_sapiens ENSP00000368258 98.895 98.3425 pan_paniscus ENSPPAP00000007169 81.3636 80.9091 ENSG00000161265 homo_sapiens ENSP00000368258 96.6851 95.0276 pongo_abelii ENSPPYP00000029480 79.5455 78.1818 ENSG00000161265 homo_sapiens ENSP00000368258 98.895 97.7901 pan_troglodytes ENSPTRP00000075776 81.3636 80.4545 ENSG00000161265 homo_sapiens ENSP00000368258 97.2376 95.5801 gorilla_gorilla ENSGGOP00000016415 80 78.6364 ENSG00000161265 homo_sapiens ENSP00000368258 86.7403 83.4254 ornithorhynchus_anatinus ENSOANP00000054703 50.6452 48.7097 ENSG00000161265 homo_sapiens ENSP00000368258 60.221 57.4586 notamacropus_eugenii ENSMEUP00000014507 64.881 61.9048 ENSG00000161265 homo_sapiens ENSP00000368258 63.5359 59.116 choloepus_hoffmanni ENSCHOP00000000913 57.2139 53.2338 ENSG00000161265 homo_sapiens ENSP00000368258 95.5801 93.9227 dasypus_novemcinctus ENSDNOP00000032842 78.6364 77.2727 ENSG00000161265 homo_sapiens ENSP00000368258 73.4807 69.6133 echinops_telfairi ENSETEP00000003918 60.4545 57.2727 ENSG00000161265 homo_sapiens ENSP00000368258 81.768 75.6906 callithrix_jacchus ENSCJAP00000075947 68.2028 63.1336 ENSG00000161265 homo_sapiens ENSP00000368258 93.3702 90.6077 cercocebus_atys ENSCATP00000031446 76.8182 74.5455 ENSG00000161265 homo_sapiens ENSP00000368258 91.7127 88.9503 macaca_mulatta ENSMMUP00000029977 76.8519 74.537 ENSG00000161265 homo_sapiens ENSP00000368258 86.1878 83.4254 macaca_nemestrina ENSMNEP00000029073 73.9336 71.564 ENSG00000161265 homo_sapiens ENSP00000368258 90.6077 87.2928 papio_anubis ENSPANP00000012844 75.2294 72.4771 ENSG00000161265 homo_sapiens ENSP00000368258 93.9227 91.7127 mandrillus_leucophaeus ENSMLEP00000001176 77.2727 75.4545 ENSG00000161265 homo_sapiens ENSP00000368258 60.7735 58.0111 tursiops_truncatus ENSTTRP00000003575 70.0637 66.879 ENSG00000161265 homo_sapiens ENSP00000368258 95.5801 93.9227 vulpes_vulpes ENSVVUP00000020384 78.6364 77.2727 ENSG00000161265 homo_sapiens ENSP00000368258 95.0276 92.8177 mus_spretus MGP_SPRETEiJ_P0082020 78.1818 76.3636 ENSG00000161265 homo_sapiens ENSP00000368258 42.5414 37.0166 equus_asinus ENSEASP00005001600 27.7978 24.1877 ENSG00000161265 homo_sapiens ENSP00000368258 95.0276 92.8177 capra_hircus ENSCHIP00000001010 78.1818 76.3636 ENSG00000161265 homo_sapiens ENSP00000368258 85.6354 83.9779 loxodonta_africana ENSLAFP00000024653 70.4545 69.0909 ENSG00000161265 homo_sapiens ENSP00000368258 95.5801 93.9227 panthera_leo ENSPLOP00000021407 78.6364 77.2727 ENSG00000161265 homo_sapiens ENSP00000368258 95.5801 93.9227 ailuropoda_melanoleuca ENSAMEP00000000633 78.6364 77.2727 ENSG00000161265 homo_sapiens ENSP00000368258 84.5304 82.3204 bos_indicus_hybrid ENSBIXP00005003327 67.1053 65.3509 ENSG00000161265 homo_sapiens ENSP00000368258 41.9889 41.9889 oryctolagus_cuniculus ENSOCUP00000027743 88.3721 88.3721 ENSG00000161265 homo_sapiens ENSP00000368258 95.5801 93.9227 equus_caballus ENSECAP00000063313 72.0833 70.8333 ENSG00000161265 homo_sapiens ENSP00000368258 95.5801 93.9227 canis_lupus_familiaris ENSCAFP00845001989 95.5801 93.9227 ENSG00000161265 homo_sapiens ENSP00000368258 95.5801 93.9227 panthera_pardus ENSPPRP00000008053 78.6364 77.2727 ENSG00000161265 homo_sapiens ENSP00000368258 53.5912 49.7238 marmota_marmota_marmota ENSMMMP00000006129 80.8333 75 ENSG00000161265 homo_sapiens ENSP00000368258 95.5801 93.9227 balaenoptera_musculus ENSBMSP00010030518 95.5801 93.9227 ENSG00000161265 homo_sapiens ENSP00000368258 83.4254 81.768 felis_catus ENSFCAP00000059590 62.9167 61.6667 ENSG00000161265 homo_sapiens ENSP00000368258 95.5801 93.9227 ursus_americanus ENSUAMP00000026751 78.6364 77.2727 ENSG00000161265 homo_sapiens ENSP00000368258 92.2652 90.0553 monodelphis_domestica ENSMODP00000017514 75.2252 73.4234 ENSG00000161265 homo_sapiens ENSP00000368258 95.0276 92.8177 bison_bison_bison ENSBBBP00000015321 78.1818 76.3636 ENSG00000161265 homo_sapiens ENSP00000368258 95.5801 93.9227 monodon_monoceros ENSMMNP00015000388 78.9954 77.6256 ENSG00000161265 homo_sapiens ENSP00000368258 95.0276 93.3702 sus_scrofa ENSSSCP00000076063 78.1818 76.8182 ENSG00000161265 homo_sapiens ENSP00000368258 75.1381 68.5083 microcebus_murinus ENSMICP00000009085 71.5789 65.2632 ENSG00000161265 homo_sapiens ENSP00000368258 94.4751 92.2652 jaculus_jaculus ENSJJAP00000003421 77.7273 75.9091 ENSG00000161265 homo_sapiens ENSP00000368258 95.0276 92.8177 ovis_aries_rambouillet ENSOARP00020025587 78.1818 76.3636 ENSG00000161265 homo_sapiens ENSP00000368258 95.5801 93.9227 ursus_maritimus ENSUMAP00000028075 74.8918 73.5931 ENSG00000161265 homo_sapiens ENSP00000368258 95.5801 93.9227 delphinapterus_leucas ENSDLEP00000003360 78.6364 77.2727 ENSG00000161265 homo_sapiens ENSP00000368258 95.5801 93.9227 physeter_catodon ENSPCTP00005018640 78.6364 77.2727 ENSG00000161265 homo_sapiens ENSP00000368258 38.674 34.8066 physeter_catodon ENSPCTP00005016197 55.5556 50 ENSG00000161265 homo_sapiens ENSP00000368258 95.0276 92.8177 mus_caroli MGP_CAROLIEiJ_P0078701 78.1818 76.3636 ENSG00000161265 homo_sapiens ENSP00000368258 95.0276 93.3702 mus_musculus ENSMUSP00000039406 78.1818 76.8182 ENSG00000161265 homo_sapiens ENSP00000368258 95.5801 93.3702 dipodomys_ordii ENSDORP00000022658 78.6364 76.8182 ENSG00000161265 homo_sapiens ENSP00000368258 94.4751 93.3702 mustela_putorius_furo ENSMPUP00000006083 74.3478 73.4783 ENSG00000161265 homo_sapiens ENSP00000368258 92.2652 90.6077 aotus_nancymaae ENSANAP00000001464 75.9091 74.5455 ENSG00000161265 homo_sapiens ENSP00000368258 90.6077 86.1878 saimiri_boliviensis_boliviensis ENSSBOP00000031591 74.5455 70.9091 ENSG00000161265 homo_sapiens ENSP00000368258 62.9834 58.5635 chlorocebus_sabaeus ENSCSAP00000000705 56.1576 52.2167 ENSG00000161265 homo_sapiens ENSP00000368258 66.8508 62.4309 mesocricetus_auratus ENSMAUP00000006105 64.0212 59.7884 ENSG00000161265 homo_sapiens ENSP00000368258 95.0276 93.3702 mesocricetus_auratus ENSMAUP00000018989 78.1818 76.8182 ENSG00000161265 homo_sapiens ENSP00000368258 44.7514 37.0166 camelus_dromedarius ENSCDRP00005020616 32.1429 26.5873 ENSG00000161265 homo_sapiens ENSP00000368258 52.4862 48.0663 carlito_syrichta ENSTSYP00000014918 54.5977 50 ENSG00000161265 homo_sapiens ENSP00000368258 95.5801 93.9227 panthera_tigris_altaica ENSPTIP00000004584 78.6364 77.2727 ENSG00000161265 homo_sapiens ENSP00000368258 80.663 75.6906 rattus_norvegicus ENSRNOP00000095413 57.4803 53.937 ENSG00000161265 homo_sapiens ENSP00000368258 85.6354 80.1105 prolemur_simus ENSPSMP00000000872 69.5067 65.0224 ENSG00000161265 homo_sapiens ENSP00000368258 94.4751 92.8177 microtus_ochrogaster ENSMOCP00000009562 77.7273 76.3636 ENSG00000161265 homo_sapiens ENSP00000368258 74.5856 70.7182 sorex_araneus ENSSARP00000001840 61.086 57.9186 ENSG00000161265 homo_sapiens ENSP00000368258 90.6077 87.2928 peromyscus_maniculatus_bairdii ENSPEMP00000013420 89.6175 86.3388 ENSG00000161265 homo_sapiens ENSP00000368258 95.0276 93.3702 peromyscus_maniculatus_bairdii ENSPEMP00000008375 78.1818 76.8182 ENSG00000161265 homo_sapiens ENSP00000368258 95.0276 92.8177 bos_mutus ENSBMUP00000023001 66.9261 65.3697 ENSG00000161265 homo_sapiens ENSP00000368258 85.6354 83.9779 mus_spicilegus ENSMSIP00000006698 69.5067 68.1614 ENSG00000161265 homo_sapiens ENSP00000368258 95.0276 93.3702 cricetulus_griseus_chok1gshd ENSCGRP00001013782 78.1818 76.8182 ENSG00000161265 homo_sapiens ENSP00000368258 59.6685 55.8011 pteropus_vampyrus ENSPVAP00000012113 55.102 51.5306 ENSG00000161265 homo_sapiens ENSP00000368258 91.7127 89.5028 vombatus_ursinus ENSVURP00010030721 40.8867 39.9015 ENSG00000161265 homo_sapiens ENSP00000368258 94.4751 92.8177 neovison_vison ENSNVIP00000021969 63.3333 62.2222 ENSG00000161265 homo_sapiens ENSP00000368258 95.0276 92.8177 bos_taurus ENSBTAP00000074433 66.9261 65.3697 ENSG00000161265 homo_sapiens ENSP00000368258 77.3481 75.1381 rhinopithecus_bieti ENSRBIP00000039479 69.6517 67.6617 ENSG00000161265 homo_sapiens ENSP00000368258 95.5801 93.9227 canis_lupus_dingo ENSCAFP00020023482 78.6364 77.2727 ENSG00000161265 homo_sapiens ENSP00000368258 95.5801 93.9227 sciurus_vulgaris ENSSVLP00005013414 78.6364 77.2727 ENSG00000161265 homo_sapiens ENSP00000368258 88.3978 86.1878 phascolarctos_cinereus ENSPCIP00000020621 52.8053 51.4851 ENSG00000161265 homo_sapiens ENSP00000368258 61.8785 51.3812 procavia_capensis ENSPCAP00000004599 58.6387 48.6911 ENSG00000161265 homo_sapiens ENSP00000368258 95.0276 93.3702 nannospalax_galili ENSNGAP00000014441 78.1818 76.8182 ENSG00000161265 homo_sapiens ENSP00000368258 53.5912 50.2762 nannospalax_galili ENSNGAP00000006468 60.625 56.875 ENSG00000161265 homo_sapiens ENSP00000368258 95.0276 92.8177 bos_grunniens ENSBGRP00000039290 66.9261 65.3697 ENSG00000161265 homo_sapiens ENSP00000368258 95.0276 92.8177 cervus_hanglu_yarkandensis ENSCHYP00000010969 78.1818 76.3636 ENSG00000161265 homo_sapiens ENSP00000368258 34.8066 30.9392 catagonus_wagneri ENSCWAP00000006333 31.1881 27.7228 ENSG00000161265 homo_sapiens ENSP00000368258 74.0331 68.5083 ictidomys_tridecemlineatus ENSSTOP00000000792 72.4324 67.027 ENSG00000161265 homo_sapiens ENSP00000368258 76.7956 73.4807 cebus_imitator ENSCCAP00000017166 68.1373 65.1961 ENSG00000161265 homo_sapiens ENSP00000368258 40.884 37.5691 urocitellus_parryii ENSUPAP00010014913 83.1461 76.4045 ENSG00000161265 homo_sapiens ENSP00000368258 95.0276 92.8177 moschus_moschiferus ENSMMSP00000002580 78.1818 76.3636 ENSG00000161265 homo_sapiens ENSP00000368258 77.3481 75.1381 rhinopithecus_roxellana ENSRROP00000021544 67.3077 65.3846 ENSG00000161265 homo_sapiens ENSP00000368258 95.0276 93.3702 mus_pahari MGP_PahariEiJ_P0015578 78.1818 76.8182 ENSG00000161265 homo_sapiens ENSP00000368258 81.2155 77.3481 propithecus_coquereli ENSPCOP00000002554 71.0145 67.6329 ENSG00000161265 homo_sapiens ENSP00000368258 75.1381 60.7735 caenorhabditis_elegans Y116A8C.35a.2 47.7193 38.5965 ENSG00000161265 homo_sapiens ENSP00000368258 82.3204 72.3757 drosophila_melanogaster FBpp0305600 56.4394 49.6212 ENSG00000161265 homo_sapiens ENSP00000368258 80.663 71.8232 ciona_intestinalis ENSCINP00000008425 66.9725 59.633 ENSG00000161265 homo_sapiens ENSP00000368258 82.3204 76.7956 eptatretus_burgeri ENSEBUP00000003662 74.1294 69.1542 ENSG00000161265 homo_sapiens ENSP00000368258 82.8729 75.1381 eptatretus_burgeri ENSEBUP00000020473 52.8169 47.8873 ENSG00000161265 homo_sapiens ENSP00000368258 66.2983 60.7735 chrysemys_picta_bellii ENSCPBP00000001738 75.9494 69.6203 ENSG00000161265 homo_sapiens ENSP00000368258 66.8508 62.9834 pelodiscus_sinensis ENSPSIP00000004613 63.0208 59.375 ENSG00000161265 homo_sapiens ENSP00000368258 88.3978 83.9779 gopherus_evgoodei ENSGEVP00005022051 72.7273 69.0909 ENSG00000161265 homo_sapiens ENSP00000368258 88.9503 83.4254 chelonoidis_abingdonii ENSCABP00000007604 73.8532 69.2661 ENSG00000161265 homo_sapiens ENSP00000368258 13.8122 11.6022 terrapene_carolina_triunguis ENSTMTP00000015249 29.4118 24.7059 ENSG00000161265 homo_sapiens ENSP00000368258 80.663 71.2707 ciona_savignyi ENSCSAVP00000000588 68.8679 60.8491 ENSG00000161265 homo_sapiens ENSP00000368258 88.3978 81.2155 leptobrachium_leishanense ENSLLEP00000041897 69.869 64.1921
Go ID
Go term
No. evidence
Entries
Species
Category
GO:0000398 involved_in mRNA splicing, via spliceosome 1 IBA Homo_sapiens(9606) Process GO:0005654 located_in nucleoplasm 1 TAS Homo_sapiens(9606) Component GO:0005681 part_of spliceosomal complex 1 IBA Homo_sapiens(9606) Component GO:0005737 located_in cytoplasm 1 IEA Homo_sapiens(9606) Component GO:0016607 located_in nuclear speck 1 IEA Homo_sapiens(9606) Component GO:0030628 enables pre-mRNA 3-splice site binding 1 IBA Homo_sapiens(9606) Function GO:0046872 enables metal ion binding 1 IEA Homo_sapiens(9606) Function GO:0089701 part_of U2AF complex 1 IBA Homo_sapiens(9606) Component
Copyright © 2023, Bioinformatics Center, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, China. All Rights Reserved.
