RBP Type	Canonical_RBPs
Diseases	N.A.
Drug	N.A.
Main interacting RNAs	rRNA
Moonlighting functions	N.A.
Localizations	N.A.
BulkPerturb-seq	N.A.

Ensembl ID	ENSG00000159111	Gene ID	124995	Accession	14055
Symbol	MRPL10	Alias	L10MT;MRPL8;RPML8;uL10m;MRP-L8;MRP-L10	Full Name	mitochondrial ribosomal protein L10
Status	Confidence	Length	8270 bases	Strand	Minus strand
Position	17 : 47823272 - 47831541	RNA binding domain	Ribosomal_L10
Summary	Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Sequence analysis identified three transcript variants that encode two different isoforms. A pseudogene corresponding to this gene is found on chromosome 5q. [provided by RefSeq, Nov 2010]