Functions and Diseases

RBP Type Non-canonical_RBPs
Diseases N.A.
Drug N.A.
Main interacting RNAs N.A.
Moonlighting functions Metabolic enzyme
Localizations N.A.
BulkPerturb-seq

Description

Ensembl ID ENSG00000157020 Gene ID 6396 Accession 10697
Symbol SEC13 Alias SEC13R;npp-20;SEC13L1;D3S1231E Full Name SEC13 homolog, nuclear pore and COPII coat complex component
Status Confidence Length 20182 bases Strand Minus strand
Position 3 : 10300931 - 10321112 RNA binding domain N.A.
Summary The protein encoded by this gene belongs to the SEC13 family of WD-repeat proteins. It is a constituent of the endoplasmic reticulum and the nuclear pore complex. It has similarity to the yeast SEC13 protein, which is required for vesicle biogenesis from endoplasmic reticulum during the transport of proteins. Multiple alternatively spliced transcript variants have been found. [provided by RefSeq, Oct 2008]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal

Transcripts

Name Transcript ID bp Protein Translation ID
SEC13-219 ENST00000492602 393 No protein -
SEC13-208 ENST00000397109 1467 308aa ENSP00000380298
SEC13-201 ENST00000337354 1363 325aa ENSP00000336566
SEC13-202 ENST00000350697 1359 322aa ENSP00000312122
SEC13-216 ENST00000479868 2374 No protein -
SEC13-209 ENST00000397117 1603 284aa ENSP00000380306
SEC13-203 ENST00000383801 1479 368aa ENSP00000373312
SEC13-215 ENST00000477547 1313 No protein -
SEC13-214 ENST00000476597 614 No protein -
SEC13-218 ENST00000490283 740 No protein -
SEC13-217 ENST00000482647 782 No protein -
SEC13-207 ENST00000397105 883 No protein -
SEC13-211 ENST00000431352 832 86aa ENSP00000401368
SEC13-206 ENST00000397102 582 No protein -
SEC13-205 ENST00000397101 592 No protein -
SEC13-204 ENST00000397099 555 No protein -
SEC13-210 ENST00000428626 567 28aa ENSP00000400260
SEC13-213 ENST00000445064 669 27aa ENSP00000398623
SEC13-212 ENST00000432213 594 24aa ENSP00000404141

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0000776colocalizes_with kinetochore1IDAHomo_sapiens(9606)Component
GO:0005198enables structural molecule activity1IBAHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005635located_in nuclear envelope1IDAHomo_sapiens(9606)Component
GO:0005643part_of nuclear pore1NASHomo_sapiens(9606)Component
GO:0005654located_in nucleoplasm1IDAHomo_sapiens(9606)Component
GO:0005765located_in lysosomal membrane2IDA,TASHomo_sapiens(9606)Component
GO:0005789located_in endoplasmic reticulum membrane1TASHomo_sapiens(9606)Component
GO:0005829located_in cytosol1TASHomo_sapiens(9606)Component
GO:0006606involved_in protein import into nucleus1IBAHomo_sapiens(9606)Process
GO:0006886involved_in intracellular protein transport1NASHomo_sapiens(9606)Process
GO:0006913involved_in nucleocytoplasmic transport1NASHomo_sapiens(9606)Process
GO:0012507located_in ER to Golgi transport vesicle membrane1TASHomo_sapiens(9606)Component
GO:0030127part_of COPII vesicle coat2IBA,IDAHomo_sapiens(9606)Component
GO:0031080part_of nuclear pore outer ring3IBA,IDA,NASHomo_sapiens(9606)Component
GO:0032008involved_in positive regulation of TOR signaling2IBA,IMPHomo_sapiens(9606)Process
GO:0032527involved_in protein exit from endoplasmic reticulum1IBAHomo_sapiens(9606)Process
GO:0042802enables identical protein binding1IPIHomo_sapiens(9606)Function
GO:0043231located_in intracellular membrane-bounded organelle1IDAHomo_sapiens(9606)Component
GO:0051028involved_in mRNA transport1IEAHomo_sapiens(9606)Process
GO:0061700part_of GATOR2 complex2IDA,NASHomo_sapiens(9606)Component
GO:0070062located_in extracellular exosome1HDAHomo_sapiens(9606)Component
GO:0090110involved_in COPII-coated vesicle cargo loading1IDAHomo_sapiens(9606)Process
GO:0090114involved_in COPII-coated vesicle budding1IBAHomo_sapiens(9606)Process
GO:1904262involved_in negative regulation of TORC1 signaling1NASHomo_sapiens(9606)Process
GO:1904263involved_in positive regulation of TORC1 signaling1NASHomo_sapiens(9606)Process

Expression