RBP Type	Canonical_RBPs
Diseases	CancerSARS-COV-2
Drug	N.A.
Main interacting RNAs	mRNA
Moonlighting functions	N.A.
Localizations	Stress granucle
BulkPerturb-seq	DataSet_02_40

Ensembl ID	ENSG00000156976	Gene ID	1974	Accession	3284
Symbol	EIF4A2	Alias	DDX2B;EIF4A;EIF4F;BM-010;NEDHSS;eIF4A-II;eIF-4A-II	Full Name	eukaryotic translation initiation factor 4A2
Status	Confidence	Length	6693 bases	Strand	Plus strand
Position	3 : 186783205 - 186789897	RNA binding domain	ResIII , DEAD
Summary	Enables ATP hydrolysis activity. Involved in negative regulation of RNA-directed 5'-3' RNA polymerase activity. Located in perinuclear region of cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

Protein	Domain	Pfam ID	E-value	Domain number
ENSP00000413529	DEAD	PF00270	2.5e-43	1
ENSP00000413529	ResIII	PF04851	3.6e-07	2
ENSP00000326381	DEAD	PF00270	3.2e-43	1
ENSP00000326381	ResIII	PF04851	4.7e-07	2
ENSP00000398370	DEAD	PF00270	3.2e-43	1
ENSP00000398370	ResIII	PF04851	4.7e-07	2
ENSP00000462571	DEAD	PF00270	1.2e-14	1
ENSP00000462571	ResIII	PF04851	5.2e-05	2
ENSP00000415878	DEAD	PF00270	1.3e-06	1

Pubmed ID	Full Name	Cell	Author	Time	Doi

Pubmed ID	Title	Author	Time	Journal
36528028	Rare EIF4A2 variants are associated with a neurodevelopmental disorder characterized by intellectual disability, hypotonia, and epilepsy.	S Maimuna Paul	2023-01-05	American journal of human genetics
31180491	DEAD-box helicase eIF4A2 inhibits CNOT7 deadenylation activity.	A Hedda Meijer	2019-09-05	Nucleic acids research
32766783	Identification and characterization of hippuristanol-resistant mutants reveals eIF4A1 dependencies within mRNA 5' leader regions.	Jutta Steinberger	2020-09-25	Nucleic acids research
31791371	eIF4A2 drives repression of translation at initiation by Ccr4-Not through purine-rich motifs in the 5'UTR.	Ania Wilczynska	2019-12-02	Genome biology
23867391	Downregulation of EIF4A2 in non-small-cell lung cancer associates with poor prognosis.	Xi Shaoyan	2013-11-01	Clinical lung cancer
27160682	Sumoylation of eIF4A2 affects stress granule formation.	Jirapas Jongjitwimol	2016-06-15	Journal of cell science
35781533	The splicing factor RBM17 drives leukemic stem cell maintenance by evading nonsense-mediated decay of pro-leukemic factors.	Lina Liu	2022-07-04	Nature communications
32575790	General and Target-Specific DExD/H RNA Helicases in Eukaryotic Translation Initiation.	Leo Shen	2020-06-20	International journal of molecular sciences
27009120	miRISC and the CCR4-NOT complex silence mRNA targets independently of 43S ribosomal scanning.	Duygu Kuzuoğlu-Öztürk	2016-06-01	The EMBO journal

Name	Transcript ID	bp	Protein	Translation ID
EIF4A2-206	ENST00000441007	480	57aa	ENSP00000407504
EIF4A2-208	ENST00000445596	600	98aa	ENSP00000415878
EIF4A2-203	ENST00000426808	1751	96aa	ENSP00000392686
EIF4A2-211	ENST00000465222	676	No protein	-
EIF4A2-221	ENST00000491473	579	No protein	-
EIF4A2-220	ENST00000486805	590	No protein	-
EIF4A2-210	ENST00000465032	578	No protein	-
EIF4A2-212	ENST00000465267	1054	No protein	-
EIF4A2-224	ENST00000495049	576	No protein	-
EIF4A2-204	ENST00000429589	1005	96aa	ENSP00000388237
EIF4A2-202	ENST00000425053	1977	362aa	ENSP00000413529
EIF4A2-201	ENST00000323963	1886	407aa	ENSP00000326381
EIF4A2-205	ENST00000440191	1889	408aa	ENSP00000398370
EIF4A2-219	ENST00000485101	5327	No protein	-
EIF4A2-218	ENST00000475653	909	No protein	-
EIF4A2-207	ENST00000443963	1729	97aa	ENSP00000402313
EIF4A2-227	ENST00000498746	579	109aa	ENSP00000462571
EIF4A2-215	ENST00000467585	570	No protein	-
EIF4A2-214	ENST00000466362	545	No protein	-
EIF4A2-216	ENST00000468362	1356	No protein	-
EIF4A2-222	ENST00000492144	993	No protein	-
EIF4A2-213	ENST00000465792	734	No protein	-
EIF4A2-217	ENST00000475409	802	No protein	-
EIF4A2-226	ENST00000497177	849	No protein	-
EIF4A2-223	ENST00000494445	629	No protein	-
EIF4A2-209	ENST00000461021	575	No protein	-
EIF4A2-225	ENST00000496382	460	No protein	-

Pathway ID	Pathway Name	Source

ensgID	Trait	pValue	Pubmed ID
88025	Adiponectin	7E-7	24105470

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
ENSG00000156976	homo_sapiens	ENSP00000379475	51.4019	33.8785	homo_sapiens	ENSP00000326381	54.0541	35.6265
ENSG00000156976	homo_sapiens	ENSP00000385536	27.1605	18.7929	homo_sapiens	ENSP00000326381	48.6486	33.6609
ENSG00000156976	homo_sapiens	ENSP00000263239	29.1045	17.0149	homo_sapiens	ENSP00000326381	47.9115	28.0098
ENSG00000156976	homo_sapiens	ENSP00000497641	80.5353	67.1533	homo_sapiens	ENSP00000326381	81.3268	67.8133
ENSG00000156976	homo_sapiens	ENSP00000482680	26.7974	15.9477	homo_sapiens	ENSP00000326381	50.3685	29.9754
ENSG00000156976	homo_sapiens	ENSP00000293831	96.3054	89.9015	homo_sapiens	ENSP00000326381	96.0688	89.6806
ENSG00000156976	homo_sapiens	ENSP00000306117	53.1381	35.1464	homo_sapiens	ENSP00000326381	62.4079	41.2776
ENSG00000156976	homo_sapiens	ENSP00000288071	53.2359	35.6994	homo_sapiens	ENSP00000326381	62.6536	42.0147
ENSG00000156976	homo_sapiens	ENSP00000481495	22.9336	13.1548	homo_sapiens	ENSP00000326381	48.403	27.7641
ENSG00000156976	homo_sapiens	ENSP00000416534	19.9612	12.2093	homo_sapiens	ENSP00000326381	50.6143	30.9582
ENSG00000156976	homo_sapiens	ENSP00000361232	25.6032	15.0134	homo_sapiens	ENSP00000326381	46.9287	27.5184
ENSG00000156976	homo_sapiens	ENSP00000492643	13.2331	7.21805	homo_sapiens	ENSP00000326381	43.2432	23.5872
ENSG00000156976	homo_sapiens	ENSP00000238146	31.3333	18.8333	homo_sapiens	ENSP00000326381	46.1916	27.7641
ENSG00000156976	homo_sapiens	ENSP00000225792	33.2248	22.1498	homo_sapiens	ENSP00000326381	50.1228	33.4152
ENSG00000156976	homo_sapiens	ENSP00000368667	31.2203	18.859	homo_sapiens	ENSP00000326381	48.403	29.2383
ENSG00000156976	homo_sapiens	ENSP00000330460	33.9257	18.9015	homo_sapiens	ENSP00000326381	51.597	28.7469
ENSG00000156976	homo_sapiens	ENSP00000263576	49.6894	32.0911	homo_sapiens	ENSP00000326381	58.9681	38.0835
ENSG00000156976	homo_sapiens	ENSP00000380495	27.027	16.0661	homo_sapiens	ENSP00000326381	44.226	26.2899
ENSG00000156976	homo_sapiens	ENSP00000314348	21.6	12.3429	homo_sapiens	ENSP00000326381	46.4373	26.5356
ENSG00000156976	homo_sapiens	ENSP00000346120	26.1814	17.1137	homo_sapiens	ENSP00000326381	50.3685	32.9238
ENSG00000156976	homo_sapiens	ENSP00000374574	19.8294	12.1535	homo_sapiens	ENSP00000326381	45.7002	28.0098
ENSG00000156976	homo_sapiens	ENSP00000358716	24.8786	16.3835	homo_sapiens	ENSP00000326381	50.3685	33.1695
ENSG00000156976	homo_sapiens	ENSP00000442266	43.6853	26.294	homo_sapiens	ENSP00000326381	51.8428	31.2039
ENSG00000156976	homo_sapiens	ENSP00000362687	27.9512	17.7748	homo_sapiens	ENSP00000326381	50.6143	32.1867
ENSG00000156976	homo_sapiens	ENSP00000479504	33.389	20.0334	homo_sapiens	ENSP00000326381	49.14	29.484
ENSG00000156976	homo_sapiens	ENSP00000359361	32.0988	20.679	homo_sapiens	ENSP00000326381	51.1057	32.9238
ENSG00000156976	homo_sapiens	ENSP00000258772	36.1974	21.755	homo_sapiens	ENSP00000326381	48.6486	29.2383
ENSG00000156976	homo_sapiens	ENSP00000494040	32.1752	19.7885	homo_sapiens	ENSP00000326381	52.3342	32.1867
ENSG00000156976	homo_sapiens	ENSP00000336725	32.4242	19.697	homo_sapiens	ENSP00000326381	52.5799	31.941
ENSG00000156976	homo_sapiens	ENSP00000247003	38.0952	25.2588	homo_sapiens	ENSP00000326381	45.2088	29.9754
ENSG00000156976	homo_sapiens	ENSP00000330349	30.2251	18.8103	homo_sapiens	ENSP00000326381	46.1916	28.7469
ENSG00000156976	homo_sapiens	ENSP00000242776	51.9906	33.7237	homo_sapiens	ENSP00000326381	54.5455	35.3808
ENSG00000156976	homo_sapiens	ENSP00000233084	29.0541	18.7838	homo_sapiens	ENSP00000326381	52.8256	34.1523
ENSG00000156976	homo_sapiens	ENSP00000304072	22.9285	13.5074	homo_sapiens	ENSP00000326381	49.6315	29.2383
ENSG00000156976	homo_sapiens	ENSP00000350698	43.2967	26.3736	homo_sapiens	ENSP00000326381	48.403	29.484
ENSG00000156976	homo_sapiens	ENSP00000310723	24.5122	15	homo_sapiens	ENSP00000326381	49.3857	30.2211
ENSG00000156976	homo_sapiens	ENSP00000332340	32.7778	20.1852	homo_sapiens	ENSP00000326381	43.4889	26.7813
ENSG00000156976	homo_sapiens	ENSP00000424838	28.3149	16.7127	homo_sapiens	ENSP00000326381	50.3685	29.7297

Ensembl ID	Source				Target
	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
ENSG00000156976	homo_sapiens	ENSP00000326381	99.5086	99.5086	nomascus_leucogenys	ENSNLEP00000008099	99.5086	99.5086
ENSG00000156976	homo_sapiens	ENSP00000326381	100	100	pan_paniscus	ENSPPAP00000003559	100	100
ENSG00000156976	homo_sapiens	ENSP00000326381	97.543	96.8059	pongo_abelii	ENSPPYP00000035935	97.066	96.3325
ENSG00000156976	homo_sapiens	ENSP00000326381	100	100	pan_troglodytes	ENSPTRP00000027042	99.7549	99.7549
ENSG00000156976	homo_sapiens	ENSP00000326381	100	100	gorilla_gorilla	ENSGGOP00000005745	100	100
ENSG00000156976	homo_sapiens	ENSP00000326381	99.5086	98.7715	ornithorhynchus_anatinus	ENSOANP00000054875	97.3558	96.6346
ENSG00000156976	homo_sapiens	ENSP00000326381	99.7543	99.0172	sarcophilus_harrisii	ENSSHAP00000028916	99.7543	99.0172
ENSG00000156976	homo_sapiens	ENSP00000326381	95.5774	94.8403	notamacropus_eugenii	ENSMEUP00000010692	96.0494	95.3086
ENSG00000156976	homo_sapiens	ENSP00000326381	79.6069	78.8698	choloepus_hoffmanni	ENSCHOP00000012415	80.597	79.8507
ENSG00000156976	homo_sapiens	ENSP00000326381	61.9165	61.9165	erinaceus_europaeus	ENSEEUP00000007820	90.3226	90.3226
ENSG00000156976	homo_sapiens	ENSP00000326381	100	99.7543	echinops_telfairi	ENSETEP00000015091	100	99.7543
ENSG00000156976	homo_sapiens	ENSP00000326381	100	100	callithrix_jacchus	ENSCJAP00000048539	100	100
ENSG00000156976	homo_sapiens	ENSP00000326381	100	100	cercocebus_atys	ENSCATP00000032517	100	100
ENSG00000156976	homo_sapiens	ENSP00000326381	51.3514	49.6315	cercocebus_atys	ENSCATP00000017920	91.2664	88.2096
ENSG00000156976	homo_sapiens	ENSP00000326381	100	100	macaca_fascicularis	ENSMFAP00000026616	100	100
ENSG00000156976	homo_sapiens	ENSP00000326381	100	100	macaca_mulatta	ENSMMUP00000038285	100	100
ENSG00000156976	homo_sapiens	ENSP00000326381	100	100	macaca_nemestrina	ENSMNEP00000028013	99.7549	99.7549
ENSG00000156976	homo_sapiens	ENSP00000326381	58.7224	56.7568	macaca_nemestrina	ENSMNEP00000044477	90.1887	87.1698
ENSG00000156976	homo_sapiens	ENSP00000326381	100	100	papio_anubis	ENSPANP00000000876	100	100
ENSG00000156976	homo_sapiens	ENSP00000326381	47.6658	45.7002	mandrillus_leucophaeus	ENSMLEP00000039892	92.381	88.5714
ENSG00000156976	homo_sapiens	ENSP00000326381	90.172	89.4349	mandrillus_leucophaeus	ENSMLEP00000004157	96.5789	95.7895
ENSG00000156976	homo_sapiens	ENSP00000326381	100	100	mandrillus_leucophaeus	ENSMLEP00000012284	100	100
ENSG00000156976	homo_sapiens	ENSP00000326381	86.4865	86.2408	tursiops_truncatus	ENSTTRP00000015962	86.4865	86.2408
ENSG00000156976	homo_sapiens	ENSP00000326381	100	99.7543	vulpes_vulpes	ENSVVUP00000017978	100	99.7543
ENSG00000156976	homo_sapiens	ENSP00000326381	100	100	mus_spretus	MGP_SPRETEiJ_P0042936	99.7549	99.7549
ENSG00000156976	homo_sapiens	ENSP00000326381	100	100	equus_asinus	ENSEASP00005020478	100	100
ENSG00000156976	homo_sapiens	ENSP00000326381	98.2801	97.7887	capra_hircus	ENSCHIP00000009579	98.0392	97.549
ENSG00000156976	homo_sapiens	ENSP00000326381	98.0344	98.0344	loxodonta_africana	ENSLAFP00000003020	97.7941	97.7941
ENSG00000156976	homo_sapiens	ENSP00000326381	100	100	panthera_leo	ENSPLOP00000006606	99.7549	99.7549
ENSG00000156976	homo_sapiens	ENSP00000326381	100	100	ailuropoda_melanoleuca	ENSAMEP00000001028	99.7549	99.7549
ENSG00000156976	homo_sapiens	ENSP00000326381	98.0344	98.0344	equus_caballus	ENSECAP00000064867	97.7941	97.7941
ENSG00000156976	homo_sapiens	ENSP00000326381	96.0688	95.3317	canis_lupus_familiaris	ENSCAFP00845029758	96.0688	95.3317
ENSG00000156976	homo_sapiens	ENSP00000326381	100	100	panthera_pardus	ENSPPRP00000015175	100	100
ENSG00000156976	homo_sapiens	ENSP00000326381	100	100	marmota_marmota_marmota	ENSMMMP00000010357	99.7549	99.7549
ENSG00000156976	homo_sapiens	ENSP00000326381	99.7543	99.5086	balaenoptera_musculus	ENSBMSP00010012314	99.7543	99.5086
ENSG00000156976	homo_sapiens	ENSP00000326381	38.8206	37.5921	cavia_porcellus	ENSCPOP00000024505	97.5309	94.4444
ENSG00000156976	homo_sapiens	ENSP00000326381	100	100	cavia_porcellus	ENSCPOP00000029199	100	100
ENSG00000156976	homo_sapiens	ENSP00000326381	100	100	felis_catus	ENSFCAP00000012873	100	100
ENSG00000156976	homo_sapiens	ENSP00000326381	98.2801	98.0344	ursus_americanus	ENSUAMP00000020193	98.0392	97.7941
ENSG00000156976	homo_sapiens	ENSP00000326381	89.6806	89.1892	monodelphis_domestica	ENSMODP00000026607	98.6487	98.1081
ENSG00000156976	homo_sapiens	ENSP00000326381	52.3342	51.1057	monodon_monoceros	ENSMMNP00015025545	95.9459	93.6937
ENSG00000156976	homo_sapiens	ENSP00000326381	99.7543	99.5086	monodon_monoceros	ENSMMNP00015002952	99.7543	99.5086
ENSG00000156976	homo_sapiens	ENSP00000326381	88.2064	88.2064	sus_scrofa	ENSSSCP00000012574	99.1713	99.1713
ENSG00000156976	homo_sapiens	ENSP00000326381	100	100	ursus_maritimus	ENSUMAP00000005329	100	100
ENSG00000156976	homo_sapiens	ENSP00000326381	98.7715	98.5258	ochotona_princeps	ENSOPRP00000003836	99.0148	98.7685
ENSG00000156976	homo_sapiens	ENSP00000326381	52.3342	50.6143	delphinapterus_leucas	ENSDLEP00000008675	95.9459	92.7928
ENSG00000156976	homo_sapiens	ENSP00000326381	98.7715	98.0344	delphinapterus_leucas	ENSDLEP00000019689	96.1722	95.4545
ENSG00000156976	homo_sapiens	ENSP00000326381	99.7543	99.5086	physeter_catodon	ENSPCTP00005015069	99.7543	99.5086
ENSG00000156976	homo_sapiens	ENSP00000326381	100	100	mus_musculus	ENSMUSP00000023599	100	100
ENSG00000156976	homo_sapiens	ENSP00000326381	81.3268	80.8354	dipodomys_ordii	ENSDORP00000019850	95.6647	95.0867
ENSG00000156976	homo_sapiens	ENSP00000326381	88.2064	88.2064	dipodomys_ordii	ENSDORP00000019476	99.1713	99.1713
ENSG00000156976	homo_sapiens	ENSP00000326381	88.2064	88.2064	mustela_putorius_furo	ENSMPUP00000003294	99.1713	99.1713
ENSG00000156976	homo_sapiens	ENSP00000326381	59.4595	57.9853	aotus_nancymaae	ENSANAP00000009624	97.9757	95.5466
ENSG00000156976	homo_sapiens	ENSP00000326381	100	100	aotus_nancymaae	ENSANAP00000019943	99.7549	99.7549
ENSG00000156976	homo_sapiens	ENSP00000326381	100	100	saimiri_boliviensis_boliviensis	ENSSBOP00000006379	100	100
ENSG00000156976	homo_sapiens	ENSP00000326381	76.1671	75.9214	saimiri_boliviensis_boliviensis	ENSSBOP00000024633	91.9881	91.6914
ENSG00000156976	homo_sapiens	ENSP00000326381	88.2064	88.2064	vicugna_pacos	ENSVPAP00000003596	87.1359	87.1359
ENSG00000156976	homo_sapiens	ENSP00000326381	88.2064	88.2064	chlorocebus_sabaeus	ENSCSAP00000005485	99.1713	99.1713
ENSG00000156976	homo_sapiens	ENSP00000326381	97.2973	97.2973	tupaia_belangeri	ENSTBEP00000001958	99.7481	99.7481
ENSG00000156976	homo_sapiens	ENSP00000326381	98.7715	98.7715	mesocricetus_auratus	ENSMAUP00000000689	99.505	99.505
ENSG00000156976	homo_sapiens	ENSP00000326381	51.8428	51.1057	phocoena_sinus	ENSPSNP00000026579	95.4751	94.1176
ENSG00000156976	homo_sapiens	ENSP00000326381	99.7543	99.5086	phocoena_sinus	ENSPSNP00000008585	99.7543	99.5086
ENSG00000156976	homo_sapiens	ENSP00000326381	100	100	camelus_dromedarius	ENSCDRP00005009628	100	100
ENSG00000156976	homo_sapiens	ENSP00000326381	100	100	carlito_syrichta	ENSTSYP00000014001	100	100
ENSG00000156976	homo_sapiens	ENSP00000326381	100	100	panthera_tigris_altaica	ENSPTIP00000010451	100	100
ENSG00000156976	homo_sapiens	ENSP00000326381	88.2064	88.2064	rattus_norvegicus	ENSRNOP00000074545	99.7222	99.7222
ENSG00000156976	homo_sapiens	ENSP00000326381	98.2801	98.2801	prolemur_simus	ENSPSMP00000026161	96.3855	96.3855
ENSG00000156976	homo_sapiens	ENSP00000326381	100	100	microtus_ochrogaster	ENSMOCP00000025841	100	100
ENSG00000156976	homo_sapiens	ENSP00000326381	84.7666	84.7666	sorex_araneus	ENSSARP00000011683	84.7666	84.7666
ENSG00000156976	homo_sapiens	ENSP00000326381	100	99.7543	peromyscus_maniculatus_bairdii	ENSPEMP00000024929	99.7549	99.5098
ENSG00000156976	homo_sapiens	ENSP00000326381	55.2826	54.0541	peromyscus_maniculatus_bairdii	ENSPEMP00000007957	97.8261	95.6522
ENSG00000156976	homo_sapiens	ENSP00000326381	96.8059	96.5602	bos_mutus	ENSBMUP00000022482	99.2443	98.9924
ENSG00000156976	homo_sapiens	ENSP00000326381	99.7543	99.7543	bos_mutus	ENSBMUP00000023982	99.5098	99.5098
ENSG00000156976	homo_sapiens	ENSP00000326381	74.2015	73.4644	bos_mutus	ENSBMUP00000000418	95.5696	94.6203
ENSG00000156976	homo_sapiens	ENSP00000326381	52.3342	51.3514	bos_mutus	ENSBMUP00000000789	98.6111	96.7593
ENSG00000156976	homo_sapiens	ENSP00000326381	90.4177	89.9263	bos_mutus	ENSBMUP00000013931	98.1333	97.6
ENSG00000156976	homo_sapiens	ENSP00000326381	100	100	cricetulus_griseus_chok1gshd	ENSCGRP00001024592	100	100
ENSG00000156976	homo_sapiens	ENSP00000326381	88.4521	88.4521	pteropus_vampyrus	ENSPVAP00000012906	88.4521	88.4521
ENSG00000156976	homo_sapiens	ENSP00000326381	99.7543	99.5086	myotis_lucifugus	ENSMLUP00000014939	99.5098	99.2647
ENSG00000156976	homo_sapiens	ENSP00000326381	99.7543	99.0172	vombatus_ursinus	ENSVURP00010015021	99.7543	99.0172
ENSG00000156976	homo_sapiens	ENSP00000326381	99.7543	99.7543	neovison_vison	ENSNVIP00000026107	99.5098	99.5098
ENSG00000156976	homo_sapiens	ENSP00000326381	100	100	bos_taurus	ENSBTAP00000019596	100	100
ENSG00000156976	homo_sapiens	ENSP00000326381	40.0491	38.8206	bos_taurus	ENSBTAP00000066862	92.0904	89.2655
ENSG00000156976	homo_sapiens	ENSP00000326381	49.3857	47.1744	rhinopithecus_bieti	ENSRBIP00000030663	89.7321	85.7143
ENSG00000156976	homo_sapiens	ENSP00000326381	99.7543	99.7543	rhinopithecus_bieti	ENSRBIP00000019382	99.7543	99.7543
ENSG00000156976	homo_sapiens	ENSP00000326381	100	100	canis_lupus_dingo	ENSCAFP00020007621	100	100
ENSG00000156976	homo_sapiens	ENSP00000326381	93.3661	92.629	sciurus_vulgaris	ENSSVLP00005005618	96.2025	95.443
ENSG00000156976	homo_sapiens	ENSP00000326381	100	100	sciurus_vulgaris	ENSSVLP00005011159	99.7549	99.7549
ENSG00000156976	homo_sapiens	ENSP00000326381	99.7543	99.0172	phascolarctos_cinereus	ENSPCIP00000016995	99.7543	99.0172
ENSG00000156976	homo_sapiens	ENSP00000326381	88.9435	88.9435	procavia_capensis	ENSPCAP00000009475	88.9435	88.9435
ENSG00000156976	homo_sapiens	ENSP00000326381	100	100	nannospalax_galili	ENSNGAP00000001001	100	100
ENSG00000156976	homo_sapiens	ENSP00000326381	64.1278	60.9337	bos_grunniens	ENSBGRP00000013755	91.2587	86.7133
ENSG00000156976	homo_sapiens	ENSP00000326381	100	100	bos_grunniens	ENSBGRP00000002720	99.7549	99.7549
ENSG00000156976	homo_sapiens	ENSP00000326381	99.0172	99.0172	chinchilla_lanigera	ENSCLAP00000021749	99.0172	99.0172
ENSG00000156976	homo_sapiens	ENSP00000326381	100	100	cervus_hanglu_yarkandensis	ENSCHYP00000028779	99.7549	99.7549
ENSG00000156976	homo_sapiens	ENSP00000326381	100	100	catagonus_wagneri	ENSCWAP00000026035	100	100
ENSG00000156976	homo_sapiens	ENSP00000326381	98.0344	98.0344	ictidomys_tridecemlineatus	ENSSTOP00000025200	97.7941	97.7941
ENSG00000156976	homo_sapiens	ENSP00000326381	85.0123	83.7838	ictidomys_tridecemlineatus	ENSSTOP00000029978	95.5801	94.1989
ENSG00000156976	homo_sapiens	ENSP00000326381	100	100	otolemur_garnettii	ENSOGAP00000009602	100	100
ENSG00000156976	homo_sapiens	ENSP00000326381	100	100	cebus_imitator	ENSCCAP00000036811	100	100
ENSG00000156976	homo_sapiens	ENSP00000326381	52.5799	51.1057	cebus_imitator	ENSCCAP00000008968	93.8596	91.2281
ENSG00000156976	homo_sapiens	ENSP00000326381	100	100	urocitellus_parryii	ENSUPAP00010001703	100	100
ENSG00000156976	homo_sapiens	ENSP00000326381	100	100	rhinopithecus_roxellana	ENSRROP00000018820	100	100
ENSG00000156976	homo_sapiens	ENSP00000326381	49.3857	47.1744	rhinopithecus_roxellana	ENSRROP00000038331	89.7321	85.7143
ENSG00000156976	homo_sapiens	ENSP00000326381	88.2064	88.2064	mus_pahari	MGP_PahariEiJ_P0028455	99.1713	99.1713
ENSG00000156976	homo_sapiens	ENSP00000326381	18.1818	17.199	propithecus_coquereli	ENSPCOP00000020975	88.0952	83.3333
ENSG00000156976	homo_sapiens	ENSP00000326381	68.3047	68.3047	propithecus_coquereli	ENSPCOP00000022106	94.8805	94.8805
ENSG00000156976	homo_sapiens	ENSP00000326381	85.7494	79.8526	eptatretus_burgeri	ENSEBUP00000015398	90.4145	84.1969
ENSG00000156976	homo_sapiens	ENSP00000326381	97.2973	94.1032	callorhinchus_milii	ENSCMIP00000018603	93.8389	90.7583
ENSG00000156976	homo_sapiens	ENSP00000326381	96.5602	94.1032	latimeria_chalumnae	ENSLACP00000020272	96.088	93.643
ENSG00000156976	homo_sapiens	ENSP00000326381	99.5086	98.0344	lepisosteus_oculatus	ENSLOCP00000000951	98.5401	97.0803
ENSG00000156976	homo_sapiens	ENSP00000326381	98.5258	95.086	clupea_harengus	ENSCHAP00000029564	97.5669	94.1606
ENSG00000156976	homo_sapiens	ENSP00000326381	98.7715	96.5602	danio_rerio	ENSDARP00000104653	97.8102	95.6204
ENSG00000156976	homo_sapiens	ENSP00000326381	98.7715	96.8059	carassius_auratus	ENSCARP00000118555	97.8102	95.8637
ENSG00000156976	homo_sapiens	ENSP00000326381	92.3833	89.9263	carassius_auratus	ENSCARP00000073073	90.8213	88.4058
ENSG00000156976	homo_sapiens	ENSP00000326381	98.7715	95.5774	astyanax_mexicanus	ENSAMXP00000019701	97.8102	94.6472
ENSG00000156976	homo_sapiens	ENSP00000326381	98.5258	95.5774	ictalurus_punctatus	ENSIPUP00000017840	97.5669	94.6472
ENSG00000156976	homo_sapiens	ENSP00000326381	96.0688	91.8919	ictalurus_punctatus	ENSIPUP00000013958	90.7193	86.7749
ENSG00000156976	homo_sapiens	ENSP00000326381	96.5602	94.3489	esox_lucius	ENSELUP00000070093	86.3736	84.3956
ENSG00000156976	homo_sapiens	ENSP00000326381	98.7715	95.5774	electrophorus_electricus	ENSEEEP00000006218	97.8102	94.6472
ENSG00000156976	homo_sapiens	ENSP00000326381	94.5946	91.4005	electrophorus_electricus	ENSEEEP00000028473	92.9952	89.8551
ENSG00000156976	homo_sapiens	ENSP00000326381	97.2973	95.086	oncorhynchus_kisutch	ENSOKIP00005057660	94.5107	92.3628
ENSG00000156976	homo_sapiens	ENSP00000326381	97.2973	95.086	oncorhynchus_mykiss	ENSOMYP00000006317	94.5107	92.3628
ENSG00000156976	homo_sapiens	ENSP00000326381	97.2973	95.086	salmo_salar	ENSSSAP00000176109	94.5107	92.3628
ENSG00000156976	homo_sapiens	ENSP00000326381	97.2973	95.086	salmo_trutta	ENSSTUP00000111618	94.5107	92.3628
ENSG00000156976	homo_sapiens	ENSP00000326381	94.5946	90.6634	gadus_morhua	ENSGMOP00000024801	93.674	89.781
ENSG00000156976	homo_sapiens	ENSP00000326381	98.7715	95.8231	fundulus_heteroclitus	ENSFHEP00000031073	97.8102	94.8905
ENSG00000156976	homo_sapiens	ENSP00000326381	98.7715	96.0688	poecilia_reticulata	ENSPREP00000009555	97.8102	95.1338
ENSG00000156976	homo_sapiens	ENSP00000326381	98.7715	96.0688	xiphophorus_maculatus	ENSXMAP00000004614	97.8102	95.1338
ENSG00000156976	homo_sapiens	ENSP00000326381	98.7715	95.8231	oryzias_latipes	ENSORLP00000011094	97.8102	94.8905
ENSG00000156976	homo_sapiens	ENSP00000326381	95.8231	90.9091	cyclopterus_lumpus	ENSCLMP00005016375	95.1219	90.2439
ENSG00000156976	homo_sapiens	ENSP00000326381	98.7715	95.3317	oreochromis_niloticus	ENSONIP00000064491	97.8102	94.4039
ENSG00000156976	homo_sapiens	ENSP00000326381	98.7715	95.3317	haplochromis_burtoni	ENSHBUP00000016062	97.8102	94.4039
ENSG00000156976	homo_sapiens	ENSP00000326381	98.7715	95.3317	astatotilapia_calliptera	ENSACLP00000015569	97.8102	94.4039
ENSG00000156976	homo_sapiens	ENSP00000326381	97.2973	93.8575	sparus_aurata	ENSSAUP00010014373	96.3504	92.944
ENSG00000156976	homo_sapiens	ENSP00000326381	94.5946	91.4005	lates_calcarifer	ENSLCAP00010052053	93.4466	90.2913
ENSG00000156976	homo_sapiens	ENSP00000326381	98.2801	96.5602	xenopus_tropicalis	ENSXETP00000095713	98.0392	96.3235
ENSG00000156976	homo_sapiens	ENSP00000326381	87.9607	85.9951	chrysemys_picta_bellii	ENSCPBP00000001201	94.709	92.5926
ENSG00000156976	homo_sapiens	ENSP00000326381	99.0172	96.8059	sphenodon_punctatus	ENSSPUP00000018345	99.0172	96.8059
ENSG00000156976	homo_sapiens	ENSP00000326381	99.2629	97.7887	crocodylus_porosus	ENSCPRP00005015262	99.2629	97.7887
ENSG00000156976	homo_sapiens	ENSP00000326381	94.3489	93.1204	laticauda_laticaudata	ENSLLTP00000003041	93.2039	91.9903
ENSG00000156976	homo_sapiens	ENSP00000326381	99.2629	98.0344	notechis_scutatus	ENSNSUP00000025086	99.5074	98.2759
ENSG00000156976	homo_sapiens	ENSP00000326381	99.2629	98.0344	pseudonaja_textilis	ENSPTXP00000025301	99.5074	98.2759
ENSG00000156976	homo_sapiens	ENSP00000326381	95.3317	94.3489	anas_platyrhynchos_platyrhynchos	ENSAPLP00000006403	99.4872	98.4615
ENSG00000156976	homo_sapiens	ENSP00000326381	99.5086	97.543	gallus_gallus	ENSGALP00010022543	97.3558	95.4327
ENSG00000156976	homo_sapiens	ENSP00000326381	99.5086	97.7887	meleagris_gallopavo	ENSMGAP00000019433	99.5086	97.7887
ENSG00000156976	homo_sapiens	ENSP00000326381	99.5086	97.7887	serinus_canaria	ENSSCAP00000018933	99.5086	97.7887
ENSG00000156976	homo_sapiens	ENSP00000326381	99.5086	97.7887	parus_major	ENSPMJP00000002117	99.5086	97.7887
ENSG00000156976	homo_sapiens	ENSP00000326381	99.2629	98.0344	anolis_carolinensis	ENSACAP00000023043	99.5074	98.2759
ENSG00000156976	homo_sapiens	ENSP00000326381	98.7715	95.3317	neolamprologus_brichardi	ENSNBRP00000005688	97.8102	94.4039
ENSG00000156976	homo_sapiens	ENSP00000326381	99.2629	98.0344	naja_naja	ENSNNAP00000017059	99.5074	98.2759
ENSG00000156976	homo_sapiens	ENSP00000326381	94.3489	93.3661	podarcis_muralis	ENSPMRP00000007489	96.2406	95.2381
ENSG00000156976	homo_sapiens	ENSP00000326381	99.5086	97.7887	geospiza_fortis	ENSGFOP00000003940	99.5086	97.7887
ENSG00000156976	homo_sapiens	ENSP00000326381	99.2629	97.2973	taeniopygia_guttata	ENSTGUP00000010794	99.0196	97.0588
ENSG00000156976	homo_sapiens	ENSP00000326381	99.2629	97.543	erpetoichthys_calabaricus	ENSECRP00000018016	98.2968	96.5937
ENSG00000156976	homo_sapiens	ENSP00000326381	97.543	93.8575	kryptolebias_marmoratus	ENSKMAP00000005330	96.3592	92.7184
ENSG00000156976	homo_sapiens	ENSP00000326381	99.2629	98.0344	salvator_merianae	ENSSMRP00000030759	99.5074	98.2759
ENSG00000156976	homo_sapiens	ENSP00000326381	91.4005	87.9607	oryzias_javanicus	ENSOJAP00000023231	91.1765	87.7451
ENSG00000156976	homo_sapiens	ENSP00000326381	97.2973	93.3661	amphilophus_citrinellus	ENSACIP00000001190	97.0588	93.1373
ENSG00000156976	homo_sapiens	ENSP00000326381	97.2973	93.6118	dicentrarchus_labrax	ENSDLAP00005001525	93.617	90.0709
ENSG00000156976	homo_sapiens	ENSP00000326381	98.7715	95.8231	amphiprion_percula	ENSAPEP00000005931	97.8102	94.8905
ENSG00000156976	homo_sapiens	ENSP00000326381	98.5258	94.5946	oryzias_sinensis	ENSOSIP00000005592	92.8241	89.1204
ENSG00000156976	homo_sapiens	ENSP00000326381	99.2629	97.7887	pelodiscus_sinensis	ENSPSIP00000019651	98.7775	97.3105
ENSG00000156976	homo_sapiens	ENSP00000326381	99.2629	97.7887	gopherus_evgoodei	ENSGEVP00005007620	99.2629	97.7887
ENSG00000156976	homo_sapiens	ENSP00000326381	99.2629	97.7887	chelonoidis_abingdonii	ENSCABP00000017608	99.2629	97.7887
ENSG00000156976	homo_sapiens	ENSP00000326381	98.7715	95.8231	seriola_dumerili	ENSSDUP00000013882	97.8102	94.8905
ENSG00000156976	homo_sapiens	ENSP00000326381	93.8575	89.6806	cottoperca_gobio	ENSCGOP00000049664	96.4646	92.1717
ENSG00000156976	homo_sapiens	ENSP00000326381	98.0344	96.8059	struthio_camelus_australis	ENSSCUP00000018766	93.2243	92.0561
ENSG00000156976	homo_sapiens	ENSP00000326381	96.8059	95.8231	anser_brachyrhynchus	ENSABRP00000011055	98.5	97.5
ENSG00000156976	homo_sapiens	ENSP00000326381	97.2973	93.3661	gasterosteus_aculeatus	ENSGACP00000021192	96.8215	92.9095
ENSG00000156976	homo_sapiens	ENSP00000326381	97.543	93.8575	cynoglossus_semilaevis	ENSCSEP00000026705	90.2273	86.8182
ENSG00000156976	homo_sapiens	ENSP00000326381	37.5921	31.941	cynoglossus_semilaevis	ENSCSEP00000026776	85	72.2222
ENSG00000156976	homo_sapiens	ENSP00000326381	98.7715	96.0688	poecilia_formosa	ENSPFOP00000004469	97.1014	94.4444
ENSG00000156976	homo_sapiens	ENSP00000326381	94.5946	93.1204	myripristis_murdjan	ENSMMDP00005031317	92.3261	90.8873
ENSG00000156976	homo_sapiens	ENSP00000326381	95.8231	91.1548	sander_lucioperca	ENSSLUP00000012619	92.1986	87.7069
ENSG00000156976	homo_sapiens	ENSP00000326381	99.5086	98.2801	strigops_habroptila	ENSSHBP00005017697	99.5086	98.2801
ENSG00000156976	homo_sapiens	ENSP00000326381	98.7715	95.8231	amphiprion_ocellaris	ENSAOCP00000032202	97.8102	94.8905
ENSG00000156976	homo_sapiens	ENSP00000326381	99.2629	97.7887	terrapene_carolina_triunguis	ENSTMTP00000014467	99.2629	97.7887
ENSG00000156976	homo_sapiens	ENSP00000326381	49.14	43.4889	hucho_hucho	ENSHHUP00000064456	70.6714	62.5442
ENSG00000156976	homo_sapiens	ENSP00000326381	97.2973	95.086	hucho_hucho	ENSHHUP00000064355	94.5107	92.3628
ENSG00000156976	homo_sapiens	ENSP00000326381	98.5258	95.3317	betta_splendens	ENSBSLP00000050134	97.5669	94.4039
ENSG00000156976	homo_sapiens	ENSP00000326381	98.7715	95.8231	anabas_testudineus	ENSATEP00000029786	97.8102	94.8905
ENSG00000156976	homo_sapiens	ENSP00000326381	98.7715	95.8231	seriola_lalandi_dorsalis	ENSSLDP00000019390	97.8102	94.8905
ENSG00000156976	homo_sapiens	ENSP00000326381	96.5602	92.1376	labrus_bergylta	ENSLBEP00000011233	95.3884	91.0194
ENSG00000156976	homo_sapiens	ENSP00000326381	98.7715	95.3317	pundamilia_nyererei	ENSPNYP00000002282	97.8102	94.4039
ENSG00000156976	homo_sapiens	ENSP00000326381	98.0344	95.086	mastacembelus_armatus	ENSMAMP00000038348	96.1446	93.253
ENSG00000156976	homo_sapiens	ENSP00000326381	98.5258	95.5774	stegastes_partitus	ENSSPAP00000003142	97.5669	94.6472
ENSG00000156976	homo_sapiens	ENSP00000326381	97.0516	94.8403	oncorhynchus_tshawytscha	ENSOTSP00005005749	94.2721	92.1241
ENSG00000156976	homo_sapiens	ENSP00000326381	98.5258	95.3317	acanthochromis_polyacanthus	ENSAPOP00000029262	97.5669	94.4039
ENSG00000156976	homo_sapiens	ENSP00000326381	99.5086	98.2801	aquila_chrysaetos_chrysaetos	ENSACCP00020002339	99.5086	98.2801
ENSG00000156976	homo_sapiens	ENSP00000326381	98.7715	95.8231	nothobranchius_furzeri	ENSNFUP00015023314	97.8102	94.8905
ENSG00000156976	homo_sapiens	ENSP00000326381	98.7715	96.0688	cyprinodon_variegatus	ENSCVAP00000002119	97.8102	95.1338
ENSG00000156976	homo_sapiens	ENSP00000326381	98.7715	97.0516	denticeps_clupeoides	ENSDCDP00000062625	88.5463	87.0044
ENSG00000156976	homo_sapiens	ENSP00000326381	98.0344	94.5946	larimichthys_crocea	ENSLCRP00005035730	97.0803	93.674
ENSG00000156976	homo_sapiens	ENSP00000326381	93.6118	89.9263	takifugu_rubripes	ENSTRUP00000084510	89.2272	85.7143
ENSG00000156976	homo_sapiens	ENSP00000326381	99.5086	97.7887	ficedula_albicollis	ENSFALP00000008576	99.5086	97.7887
ENSG00000156976	homo_sapiens	ENSP00000326381	98.2801	95.086	hippocampus_comes	ENSHCOP00000016887	98.2801	95.086
ENSG00000156976	homo_sapiens	ENSP00000326381	95.8231	92.3833	cyprinus_carpio_carpio	ENSCCRP00000120654	91.9811	88.6792
ENSG00000156976	homo_sapiens	ENSP00000326381	98.7715	96.5602	cyprinus_carpio_carpio	ENSCCRP00000147276	97.8102	95.6204
ENSG00000156976	homo_sapiens	ENSP00000326381	99.5086	97.7887	coturnix_japonica	ENSCJPP00005016814	99.5086	97.7887
ENSG00000156976	homo_sapiens	ENSP00000326381	98.7715	96.0688	poecilia_latipinna	ENSPLAP00000022879	97.8102	95.1338
ENSG00000156976	homo_sapiens	ENSP00000326381	98.7715	97.0516	sinocyclocheilus_grahami	ENSSGRP00000054007	97.8102	96.1071
ENSG00000156976	homo_sapiens	ENSP00000326381	98.0344	95.5774	sinocyclocheilus_grahami	ENSSGRP00000011581	94.1038	91.7453
ENSG00000156976	homo_sapiens	ENSP00000326381	98.7715	95.3317	maylandia_zebra	ENSMZEP00005008966	97.8102	94.4039
ENSG00000156976	homo_sapiens	ENSP00000326381	83.2924	77.1499	tetraodon_nigroviridis	ENSTNIP00000010641	84.5387	78.3042
ENSG00000156976	homo_sapiens	ENSP00000326381	98.0344	96.3145	paramormyrops_kingsleyae	ENSPKIP00000034606	97.0803	95.3771
ENSG00000156976	homo_sapiens	ENSP00000326381	94.8403	92.8747	paramormyrops_kingsleyae	ENSPKIP00000006546	92.3445	90.4306
ENSG00000156976	homo_sapiens	ENSP00000326381	95.086	92.3833	scleropages_formosus	ENSSFOP00015061204	93.7046	91.0412
ENSG00000156976	homo_sapiens	ENSP00000326381	97.0516	94.3489	scleropages_formosus	ENSSFOP00015021528	94.9519	92.3077
ENSG00000156976	homo_sapiens	ENSP00000326381	90.9091	88.6978	leptobrachium_leishanense	ENSLLEP00000009305	89.5884	87.4092
ENSG00000156976	homo_sapiens	ENSP00000326381	94.5946	90.9091	scophthalmus_maximus	ENSSMAP00000050236	93.4466	89.8058
ENSG00000156976	homo_sapiens	ENSP00000326381	98.7715	95.8231	oryzias_melastigma	ENSOMEP00000005153	97.8102	94.8905

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0002183	involved_in cytoplasmic translational initiation	1	IBA	Homo_sapiens(9606)	Process
GO:0003723	enables RNA binding	1	HDA	Homo_sapiens(9606)	Function
GO:0003724	enables RNA helicase activity	1	IEA	Homo_sapiens(9606)	Function
GO:0003743	enables translation initiation factor activity	1	IBA	Homo_sapiens(9606)	Function
GO:0004386	enables helicase activity	1	TAS	Homo_sapiens(9606)	Function
GO:0005515	enables protein binding	1	IPI	Homo_sapiens(9606)	Function
GO:0005524	enables ATP binding	1	IEA	Homo_sapiens(9606)	Function
GO:0005829	located_in cytosol	1	TAS	Homo_sapiens(9606)	Component
GO:0006413	involved_in translational initiation	1	NAS	Homo_sapiens(9606)	Process
GO:0006446	involved_in regulation of translational initiation	1	TAS	Homo_sapiens(9606)	Process
GO:0016281	part_of eukaryotic translation initiation factor 4F complex	1	NAS	Homo_sapiens(9606)	Component
GO:0016887	enables ATP hydrolysis activity	1	IDA	Homo_sapiens(9606)	Function
GO:0048471	located_in perinuclear region of cytoplasm	1	IDA	Homo_sapiens(9606)	Component
GO:1900260	involved_in negative regulation of RNA-dependent RNA polymerase activity	1	IDA	Homo_sapiens(9606)	Process
GO:1990830	involved_in cellular response to leukemia inhibitory factor	1	IEA	Homo_sapiens(9606)	Process