Functions and Diseases

RBP Type Canonical_RBPs
Diseases N.A.
Drug N.A.
Main interacting RNAs N.A.
Moonlighting functions E3 ligaseDUB
Localizations N.A.
BulkPerturb-seq

Description

Ensembl ID ENSG00000154370 Gene ID 81559 Accession 16281
Symbol TRIM11 Alias BIA1;RNF92 Full Name tripartite motif containing 11
Status Confidence Length 13163 bases Strand Minus strand
Position 1 : 228393673 - 228406835 RNA binding domain SPRY
Summary The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to the nucleus and the cytoplasm. Its function has not been identified. [provided by RefSeq, Jul 2008]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000473360 SPRY PF00622 6.4e-13 1
ENSP00000284551 SPRY PF00622 1.1e-12 1
ENSP00000473574 SPRY PF00622 2.5e-11 1

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal

Transcripts

Name Transcript ID bp Protein Translation ID
TRIM11-204 ENST00000493030 5774 343aa ENSP00000473360
TRIM11-201 ENST00000284551 2710 468aa ENSP00000284551
TRIM11-206 ENST00000602582 682 228aa ENSP00000473574
TRIM11-203 ENST00000475775 693 No protein -
TRIM11-202 ENST00000366699 2511 385aa ENSP00000355660
TRIM11-205 ENST00000602308 586 54aa ENSP00000473579

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID
92539Hip4E-625271088
92541Stress, Psychological4E-625271088

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0004842enables ubiquitin-protein transferase activity1IDAHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005654located_in nucleoplasm1IDAHomo_sapiens(9606)Component
GO:0005737is_active_in cytoplasm2IBA,IDAHomo_sapiens(9606)Component
GO:0005829is_active_in cytosol2IBA,IDAHomo_sapiens(9606)Component
GO:0008270enables zinc ion binding1IEAHomo_sapiens(9606)Function
GO:0010468involved_in regulation of gene expression1IBAHomo_sapiens(9606)Process
GO:0016567involved_in protein ubiquitination2IBA,IDAHomo_sapiens(9606)Process
GO:0019904enables protein domain specific binding1IEAHomo_sapiens(9606)Function
GO:0030674enables protein-macromolecule adaptor activity1IDAHomo_sapiens(9606)Function
GO:0032897involved_in negative regulation of viral transcription1IDAHomo_sapiens(9606)Process
GO:0044790involved_in suppression of viral release by host2IDA,IMPHomo_sapiens(9606)Process
GO:0045087involved_in innate immune response1IMPHomo_sapiens(9606)Process
GO:0045892involved_in negative regulation of DNA-templated transcription1IEAHomo_sapiens(9606)Process
GO:0046597involved_in negative regulation of viral entry into host cell1IMPHomo_sapiens(9606)Process
GO:0046598involved_in positive regulation of viral entry into host cell1IMPHomo_sapiens(9606)Process
GO:0050768involved_in negative regulation of neurogenesis1IEAHomo_sapiens(9606)Process
GO:0051865involved_in protein autoubiquitination1IDAHomo_sapiens(9606)Process
GO:0061630enables ubiquitin protein ligase activity1IBAHomo_sapiens(9606)Function
GO:0140972involved_in negative regulation of AIM2 inflammasome complex assembly1IDAHomo_sapiens(9606)Process

Expression