Functions and Diseases

RBP Type Canonical_RBPs
Diseases N.A.
Drug N.A.
Main interacting RNAs mRNA
Moonlighting functions N.A.
Localizations Stress granucleP-body
BulkPerturb-seq DataSet_01_226 DataSet_01_332

Description

Ensembl ID ENSG00000151461 Gene ID 26019 Accession 17854
Symbol UPF2 Alias HUPF2;RENT2;smg-3 Full Name UPF2 regulator of nonsense mediated mRNA decay
Status Confidence Length 123149 bases Strand Minus strand
Position 10 : 11920022 - 12043170 RNA binding domain Upf2 , MIF4G
Summary This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located in the perinuclear area. It interacts with translation release factors and the proteins that are functional homologs of yeast Upf1p and Upf3p. Two splice variants have been found for this gene; both variants encode the same protein. [provided by RefSeq, Jul 2008]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000348708 MIF4G PF02854 4.5e-80 1
ENSP00000348708 MIF4G PF02854 4.5e-80 2
ENSP00000348708 MIF4G PF02854 4.5e-80 3
ENSP00000348708 Upf2 PF04050 1.3e-31 4
ENSP00000350221 MIF4G PF02854 4.5e-80 1
ENSP00000350221 MIF4G PF02854 4.5e-80 2
ENSP00000350221 MIF4G PF02854 4.5e-80 3
ENSP00000350221 Upf2 PF04050 1.3e-31 4
ENSP00000380244 MIF4G PF02854 4.5e-80 1
ENSP00000380244 MIF4G PF02854 4.5e-80 2
ENSP00000380244 MIF4G PF02854 4.5e-80 3
ENSP00000380244 Upf2 PF04050 1.3e-31 4

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal
27221324 Nonsense-mediated mRNA decay factor Upf2 exists in both the nucleoplasm and the cytoplasm. Takanori Tatsuno 2016-07-01 Molecular medicine reports
35640974 Structures of nonsense-mediated mRNA decay factors UPF3B and UPF3A in complex with UPF2 reveal molecular basis for competitive binding and for neurodevelopmental disorder-causing mutation. C Joshua Bufton 2022-06-10 Nucleic acids research
22363630 Post-transcriptional regulation of 5-lipoxygenase mRNA expression via alternative splicing and nonsense-mediated mRNA decay. J Meike Ochs 2012-01-01 PloS one
27173476 Nonsense-mediated mRNA decay: novel mechanistic insights and biological impact. D Evangelos Karousis 2016-09-01 Wiley interdisciplinary reviews. RNA
36456182 Modulation of RNA-binding properties of the RNA helicase UPF1 by its activator UPF2. Guangpu Xue 2023-02-01 RNA (New York, N.Y.)
29333258 An RNA decay factor wears a new coat: UPF3B modulates translation termination. Zhaofeng Gao 2017-01-01 F1000Research
37366629 Nonsense-mediated decay machinery in Plasmodium falciparum is inefficient and non-essential. Emma McHugh 2023-08-24 mSphere
22713324 Biochemical characterization of the RNA helicase UPF1 involved in nonsense-mediated mRNA decay. Francesca Fiorini 2012-01-01 Methods in enzymology
19909264 Gene expression networks: competing mRNA decay pathways in mammalian cells. E Lynne Maquat 2009-12-01 Biochemical Society transactions
23602935 Signaling pathways that control mRNA turnover. Roopa Thapar 2013-08-01 Cellular signalling
32213869 Nonsense-Mediated mRNA Decay: Pathologies and the Potential for Novel Therapeutics. Kamila Pawlicka 2020-03-24 Cancers
26436458 Nonsense-Mediated mRNA Decay: Degradation of Defective Transcripts Is Only Part of the Story. Feng He 2015-01-01 Annual review of genetics
36979640 Recoding of Nonsense Mutation as a Pharmacological Strategy. Gazmend Temaj 2023-02-22 Biomedicines
21419344 Molecular mechanisms for the RNA-dependent ATPase activity of Upf1 and its regulation by Upf2. Sutapa Chakrabarti 2011-03-18 Molecular cell
35774399 HibeRNAtion: HIV-1 RNA Metabolism and Viral Latency. Raquel Crespo 2022-01-01 Frontiers in cellular and infection microbiology
35675814 AKT constitutes a signal-promoted alternative exon-junction complex that regulates nonsense-mediated mRNA decay. Hana Cho 2022-08-04 Molecular cell

Transcripts

Name Transcript ID bp Protein Translation ID
UPF2-201 ENST00000356352 5569 1272aa ENSP00000348708
UPF2-202 ENST00000357604 5168 1272aa ENSP00000350221
UPF2-203 ENST00000397053 5369 1272aa ENSP00000380244
UPF2-204 ENST00000460569 640 No protein -

Gene Model

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID
81423Prostatic Neoplasms7E-722219177

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000151461

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000151461homo_sapiensENSP0000035022199.921499.5283nomascus_leucogenysENSNLEP0000001467399.921499.5283
ENSG00000151461homo_sapiensENSP0000035022197.012696.8553pan_paniscusENSPPAP0000002991198.170298.0111
ENSG00000151461homo_sapiensENSP0000035022199.921499.6855pongo_abeliiENSPPYP0000000242399.921499.6855
ENSG00000151461homo_sapiensENSP0000035022110099.9214pan_troglodytesENSPTRP0000000387310099.9214
ENSG00000151461homo_sapiensENSP0000035022110099.9214gorilla_gorillaENSGGOP0000001837510099.9214
ENSG00000151461homo_sapiensENSP0000035022197.641594.9686ornithorhynchus_anatinusENSOANP0000002426395.538592.9231
ENSG00000151461homo_sapiensENSP0000035022198.113295.1258sarcophilus_harrisiiENSSHAP0000003902798.190495.2006
ENSG00000151461homo_sapiensENSP0000035022152.122648.5849notamacropus_eugeniiENSMEUP0000000200455.066451.3289
ENSG00000151461homo_sapiensENSP0000035022183.490681.8396choloepus_hoffmanniENSCHOP0000000037886.552684.8411
ENSG00000151461homo_sapiensENSP0000035022199.213897.7201dasypus_novemcinctusENSDNOP0000002262899.291997.797
ENSG00000151461homo_sapiensENSP0000035022172.248469.7327erinaceus_europaeusENSEEUP0000000718972.705770.174
ENSG00000151461homo_sapiensENSP0000035022159.43458.0975echinops_telfairiENSETEP0000000939959.480758.1432
ENSG00000151461homo_sapiensENSP0000035022199.449798.8208callithrix_jacchusENSCJAP0000008062198.520297.8972
ENSG00000151461homo_sapiensENSP0000035022199.842899.6069cercocebus_atysENSCATP0000001766599.842899.6069
ENSG00000151461homo_sapiensENSP0000035022199.842899.5283macaca_fascicularisENSMFAP0000002470399.842899.5283
ENSG00000151461homo_sapiensENSP0000035022199.764299.4497macaca_mulattaENSMMUP0000007776497.690597.3826
ENSG00000151461homo_sapiensENSP0000035022180.188779.8742macaca_nemestrinaENSMNEP0000000179099.512299.1219
ENSG00000151461homo_sapiensENSP0000035022114.54413.8365macaca_nemestrinaENSMNEP0000002331291.584287.1287
ENSG00000151461homo_sapiensENSP0000035022199.606999.3711papio_anubisENSPANP0000001987299.216998.982
ENSG00000151461homo_sapiensENSP0000035022197.405797.0912mandrillus_leucophaeusENSMLEP0000002402498.177597.8605
ENSG00000151461homo_sapiensENSP0000035022198.97897.6415tursiops_truncatusENSTTRP0000001553299.133997.7953
ENSG00000151461homo_sapiensENSP0000035022199.056697.6415vulpes_vulpesENSVVUP0000000814899.134597.7183
ENSG00000151461homo_sapiensENSP0000035022198.742197.0912mus_spretusMGP_SPRETEiJ_P005147898.975697.3207
ENSG00000151461homo_sapiensENSP0000035022198.820897.6415equus_asinusENSEASP0000502835995.589494.4487
ENSG00000151461homo_sapiensENSP0000035022198.820897.5629capra_hircusENSCHIP0000002235198.820897.5629
ENSG00000151461homo_sapiensENSP0000035022199.213897.5629panthera_leoENSPLOP0000001646799.291997.6397
ENSG00000151461homo_sapiensENSP0000035022196.147894.8113ailuropoda_melanoleucaENSAMEP0000000485394.221992.9122
ENSG00000151461homo_sapiensENSP0000035022198.899497.6415bos_indicus_hybridENSBIXP0000500809998.281297.0312
ENSG00000151461homo_sapiensENSP0000035022198.820897.4843oryctolagus_cuniculusENSOCUP0000000539499.446298.1013
ENSG00000151461homo_sapiensENSP0000035022199.056697.956equus_caballusENSECAP0000001490998.514597.4199
ENSG00000151461homo_sapiensENSP0000035022199.056697.7201canis_lupus_familiarisENSCAFP0084500048699.134597.797
ENSG00000151461homo_sapiensENSP0000035022199.213897.5629panthera_pardusENSPPRP0000000467199.291997.6397
ENSG00000151461homo_sapiensENSP0000035022191.823990.173marmota_marmota_marmotaENSMMMP0000001880699.151197.3684
ENSG00000151461homo_sapiensENSP0000035022199.135298.0346balaenoptera_musculusENSBMSP0001000715099.291398.189
ENSG00000151461homo_sapiensENSP0000035022197.091294.6541cavia_porcellusENSCPOP0000000790798.642296.1661
ENSG00000151461homo_sapiensENSP0000035022196.540994.6541felis_catusENSFCAP0000002041196.540994.6541
ENSG00000151461homo_sapiensENSP0000035022193.789392.6101ursus_americanusENSUAMP0000003081099.004297.7593
ENSG00000151461homo_sapiensENSP0000035022198.191895.2044monodelphis_domesticaENSMODP0000004967494.335491.4653
ENSG00000151461homo_sapiensENSP0000035022198.899497.6415bison_bison_bisonENSBBBP0000000983898.977297.7183
ENSG00000151461homo_sapiensENSP0000035022199.056697.7987monodon_monocerosENSMMNP0001502223499.212697.9528
ENSG00000151461homo_sapiensENSP0000035022198.899497.5629sus_scrofaENSSSCP0000002785299.055197.7165
ENSG00000151461homo_sapiensENSP0000035022194.811393.6321microcebus_murinusENSMICP0000003747999.50598.2673
ENSG00000151461homo_sapiensENSP0000035022198.820896.6195octodon_degusENSODEP0000000163298.976496.7717
ENSG00000151461homo_sapiensENSP0000035022198.506396.2264jaculus_jaculusENSJJAP0000000269698.81796.53
ENSG00000151461homo_sapiensENSP0000035022198.97897.7201ovis_aries_rambouilletENSOARP0002000740099.055997.797
ENSG00000151461homo_sapiensENSP0000035022199.135297.956ursus_maritimusENSUMAP0000001764694.386293.2635
ENSG00000151461homo_sapiensENSP0000035022180.660478.695ochotona_princepsENSOPRP0000000624381.493279.5075
ENSG00000151461homo_sapiensENSP0000035022199.056697.7987delphinapterus_leucasENSDLEP0000000591199.212697.9528
ENSG00000151461homo_sapiensENSP0000035022199.135297.956physeter_catodonENSPCTP0000500526699.291398.1102
ENSG00000151461homo_sapiensENSP0000035022198.663596.8553mus_caroliMGP_CAROLIEiJ_P004946898.896897.0843
ENSG00000151461homo_sapiensENSP0000035022198.663596.8553mus_musculusENSMUSP0000005837598.896897.0843
ENSG00000151461homo_sapiensENSP0000035022198.742196.934dipodomys_ordiiENSDORP0000000232798.897697.0866
ENSG00000151461homo_sapiensENSP0000035022199.292497.7201mustela_putorius_furoENSMPUP0000000105699.370697.797
ENSG00000151461homo_sapiensENSP0000035022191.19589.4654aotus_nancymaaeENSANAP0000002133797.47995.6302
ENSG00000151461homo_sapiensENSP0000035022199.606998.8208saimiri_boliviensis_boliviensisENSSBOP0000000628199.763898.9764
ENSG00000151461homo_sapiensENSP0000035022180.817678.3805vicugna_pacosENSVPAP0000000628581.072678.6278
ENSG00000151461homo_sapiensENSP0000035022199.921499.6855chlorocebus_sabaeusENSCSAP0000000953499.921499.6855
ENSG00000151461homo_sapiensENSP0000035022185.691884.3553tupaia_belangeriENSTBEP0000001103386.0384.6882
ENSG00000151461homo_sapiensENSP0000035022196.619594.8899mesocricetus_auratusENSMAUP0000001775699.112997.3387
ENSG00000151461homo_sapiensENSP0000035022194.418292.7673phocoena_sinusENSPSNP0000002559997.56395.857
ENSG00000151461homo_sapiensENSP0000035022129.245328.2233camelus_dromedariusENSCDRP0000502776297.637894.2257
ENSG00000151461homo_sapiensENSP0000035022127.830227.4371camelus_dromedariusENSCDRP0000501590996.721395.3552
ENSG00000151461homo_sapiensENSP0000035022199.292497.8774carlito_syrichtaENSTSYP0000001533199.370697.9544
ENSG00000151461homo_sapiensENSP0000035022199.213897.5629panthera_tigris_altaicaENSPTIP0000000714399.291997.6397
ENSG00000151461homo_sapiensENSP0000035022198.663596.934rattus_norvegicusENSRNOP0000007579598.741197.0102
ENSG00000151461homo_sapiensENSP0000035022198.584996.6195microtus_ochrogasterENSMOCP0000000829998.895996.9243
ENSG00000151461homo_sapiensENSP0000035022197.169895.283sorex_araneusENSSARP0000000779297.246395.358
ENSG00000151461homo_sapiensENSP0000035022198.820897.1698peromyscus_maniculatus_bairdiiENSPEMP0000001654699.054497.3995
ENSG00000151461homo_sapiensENSP0000035022198.663597.4843bos_mutusENSBMUP0000001825198.896897.7147
ENSG00000151461homo_sapiensENSP0000035022198.742197.0126mus_spicilegusENSMSIP0000001997698.975697.2419
ENSG00000151461homo_sapiensENSP0000035022198.820897.2484cricetulus_griseus_chok1gshdENSCGRP0000102009099.054497.4783
ENSG00000151461homo_sapiensENSP0000035022191.981190.2516pteropus_vampyrusENSPVAP0000001630991.981190.2516
ENSG00000151461homo_sapiensENSP0000035022198.820897.1698myotis_lucifugusENSMLUP0000000021198.743197.0935
ENSG00000151461homo_sapiensENSP0000035022197.877495.2044vombatus_ursinusENSVURP0001001854597.954495.2793
ENSG00000151461homo_sapiensENSP0000035022198.899497.327rhinolophus_ferrumequinumENSRFEP0001002805698.899497.327
ENSG00000151461homo_sapiensENSP0000035022199.213897.7201neovison_visonENSNVIP0000002819699.291997.797
ENSG00000151461homo_sapiensENSP0000035022198.899497.6415bos_taurusENSBTAP0000006284098.977297.7183
ENSG00000151461homo_sapiensENSP0000035022191.902590.6447heterocephalus_glaber_femaleENSHGLP0000005289797.173795.8437
ENSG00000151461homo_sapiensENSP0000035022198.584998.2704rhinopithecus_bietiENSRBIP0000002784699.761399.4431
ENSG00000151461homo_sapiensENSP0000035022196.698195.1258canis_lupus_dingoENSCAFP0002000756798.321396.7226
ENSG00000151461homo_sapiensENSP0000035022199.135297.5629sciurus_vulgarisENSSVLP0000501314399.291397.7165
ENSG00000151461homo_sapiensENSP0000035022126.965425.7862phascolarctos_cinereusENSPCIP0000000798796.348392.1348
ENSG00000151461homo_sapiensENSP0000035022136.871134.5912phascolarctos_cinereusENSPCIP0000000799187.992582.5516
ENSG00000151461homo_sapiensENSP0000035022127.751626.6509phascolarctos_cinereusENSPCIP0000004460598.055694.1667
ENSG00000151461homo_sapiensENSP0000035022184.984383.3333procavia_capensisENSPCAP0000000067585.725684.0603
ENSG00000151461homo_sapiensENSP0000035022198.820897.5629bos_grunniensENSBGRP0000001977798.976497.7165
ENSG00000151461homo_sapiensENSP0000035022198.97897.0912chinchilla_lanigeraENSCLAP0000001664399.133997.2441
ENSG00000151461homo_sapiensENSP0000035022198.899497.6415cervus_hanglu_yarkandensisENSCHYP0000003606298.977297.7183
ENSG00000151461homo_sapiensENSP0000035022199.213897.7201catagonus_wagneriENSCWAP0000002785899.291997.797
ENSG00000151461homo_sapiensENSP0000035022199.056697.4057ictidomys_tridecemlineatusENSSTOP0000001172499.212697.5591
ENSG00000151461homo_sapiensENSP0000035022199.213898.1918otolemur_garnettiiENSOGAP0000000518599.291998.2691
ENSG00000151461homo_sapiensENSP0000035022192.845991.6667cebus_imitatorENSCCAP0000003616595.70594.4895
ENSG00000151461homo_sapiensENSP0000035022199.056697.4843urocitellus_parryiiENSUPAP0001001096899.212697.6378
ENSG00000151461homo_sapiensENSP0000035022198.97897.7987moschus_moschiferusENSMMSP0000001990699.133997.9528
ENSG00000151461homo_sapiensENSP0000035022199.764299.4497rhinopithecus_roxellanaENSRROP0000004063099.842699.5279
ENSG00000151461homo_sapiensENSP0000035022198.663596.4623mus_pahariMGP_PahariEiJ_P004001998.896896.6903
ENSG00000151461homo_sapiensENSP0000035022196.540995.3616propithecus_coquereliENSPCOP0000001942899.513898.2982
ENSG00000151461homo_sapiensENSP0000035022144.889925.7075caenorhabditis_elegansY73B6BL.18b.149.912628.5839
ENSG00000151461homo_sapiensENSP0000035022154.088136.1635drosophila_melanogasterFBpp007107255.439237.0669
ENSG00000151461homo_sapiensENSP0000035022110.53467.62579ciona_intestinalisENSCINP0000000588069.791750.5208
ENSG00000151461homo_sapiensENSP0000035022125.864820.5975petromyzon_marinusENSPMAP0000000894680.835464.3735
ENSG00000151461homo_sapiensENSP0000035022118.474812.5786eptatretus_burgeriENSEBUP0000002063865.826344.8179
ENSG00000151461homo_sapiensENSP0000035022188.915180.2673callorhinchus_miliiENSCMIP0000002851292.326583.3469
ENSG00000151461homo_sapiensENSP0000035022189.072379.717latimeria_chalumnaeENSLACP0000001809989.002479.6544
ENSG00000151461homo_sapiensENSP0000035022193.081885.8491lepisosteus_oculatusENSLOCP0000001932793.15585.9166
ENSG00000151461homo_sapiensENSP0000035022191.19581.9182clupea_harengusENSCHAP0000002766090.62581.4062
ENSG00000151461homo_sapiensENSP0000035022133.411929.9528danio_rerioENSDARP0000015459590.425581.0638
ENSG00000151461homo_sapiensENSP0000035022190.17380.6604carassius_auratusENSCARP0000003057386.631477.4924
ENSG00000151461homo_sapiensENSP0000035022118.003116.3522carassius_auratusENSCARP0000009773590.87382.5397
ENSG00000151461homo_sapiensENSP0000035022189.229679.5597carassius_auratusENSCARP0000003189190.150980.3813
ENSG00000151461homo_sapiensENSP0000035022192.845983.6478astyanax_mexicanusENSAMXP0000001410091.692582.6087
ENSG00000151461homo_sapiensENSP0000035022190.56681.4465ictalurus_punctatusENSIPUP0000002326989.510580.4973
ENSG00000151461homo_sapiensENSP0000035022192.452882.9403esox_luciusENSELUP0000001168588.288379.2042
ENSG00000151461homo_sapiensENSP0000035022191.116482.5472electrophorus_electricusENSEEEP0000000341091.548282.9384
ENSG00000151461homo_sapiensENSP0000035022191.588182.1541oncorhynchus_kisutchENSOKIP0000503914386.104977.2358
ENSG00000151461homo_sapiensENSP0000035022191.902582.6258oncorhynchus_kisutchENSOKIP0000502891488.293179.3807
ENSG00000151461homo_sapiensENSP0000035022191.509482.3113oncorhynchus_mykissENSOMYP0000003043591.151181.989
ENSG00000151461homo_sapiensENSP0000035022191.981182.4686oncorhynchus_mykissENSOMYP000000476169080.6923
ENSG00000151461homo_sapiensENSP0000035022191.902582.7044salmo_salarENSSSAP0000006098186.464577.8107
ENSG00000151461homo_sapiensENSP0000035022191.902582.4686salmo_salarENSSSAP0000006096686.721177.819
ENSG00000151461homo_sapiensENSP0000035022191.902582.6258salmo_truttaENSSTUP0000011330586.464577.7367
ENSG00000151461homo_sapiensENSP0000035022191.902582.5472salmo_truttaENSSTUP0000000455888.627779.6058
ENSG00000151461homo_sapiensENSP0000035022188.993780.4245gadus_morhuaENSGMOP0000002368689.063780.4878
ENSG00000151461homo_sapiensENSP0000035022191.037782.3113fundulus_heteroclitusENSFHEP0000002679489.351980.787
ENSG00000151461homo_sapiensENSP0000035022191.509482.3113poecilia_reticulataENSPREP0000003230092.161582.8979
ENSG00000151461homo_sapiensENSP0000035022191.430882.1541xiphophorus_maculatusENSXMAP0000001727388.982479.9541
ENSG00000151461homo_sapiensENSP0000035022191.509483.0975oryzias_latipesENSORLP0000002150791.294182.902
ENSG00000151461homo_sapiensENSP0000035022191.430881.9182cyclopterus_lumpusENSCLMP0000502302291.215781.7255
ENSG00000151461homo_sapiensENSP0000035022192.295683.8836oreochromis_niloticusENSONIP0000002266892.078483.6863
ENSG00000151461homo_sapiensENSP0000035022192.138483.6478haplochromis_burtoniENSHBUP0000002339990.153881.8462
ENSG00000151461homo_sapiensENSP0000035022192.138483.6478astatotilapia_callipteraENSACLP0000001859389.877381.5951
ENSG00000151461homo_sapiensENSP0000035022192.374283.6478sparus_aurataENSSAUP0001005957191.940583.2551
ENSG00000151461homo_sapiensENSP0000035022191.981183.805lates_calcariferENSLCAP0001000501287.509379.7307
ENSG00000151461homo_sapiensENSP0000035022194.103887.2642xenopus_tropicalisENSXETP0000008862094.624587.747
ENSG00000151461homo_sapiensENSP0000035022196.30592.2956chrysemys_picta_belliiENSCPBP0000004048697.609693.5458
ENSG00000151461homo_sapiensENSP0000035022194.418289.7799sphenodon_punctatusENSSPUP0000001927095.317590.6349
ENSG00000151461homo_sapiensENSP0000035022197.32793.3176crocodylus_porosusENSCPRP0000500112795.894791.9442
ENSG00000151461homo_sapiensENSP0000035022165.015762.5laticauda_laticaudataENSLLTP0000001172195.828592.1205
ENSG00000151461homo_sapiensENSP0000035022122.641521.934laticauda_laticaudataENSLLTP0000001174397.297394.2568
ENSG00000151461homo_sapiensENSP0000035022126.415124.3711notechis_scutatusENSNSUP0000001066294.117686.8347
ENSG00000151461homo_sapiensENSP0000035022122.95622.2484notechis_scutatusENSNSUP0000001066397.986694.9664
ENSG00000151461homo_sapiensENSP0000035022196.462391.195pseudonaja_textilisENSPTXP0000000162094.96989.7833
ENSG00000151461homo_sapiensENSP0000035022197.169892.9245anas_platyrhynchos_platyrhynchosENSAPLP0000002997495.003890.8532
ENSG00000151461homo_sapiensENSP0000035022197.32793.239gallus_gallusENSGALP0001000818395.524791.5123
ENSG00000151461homo_sapiensENSP0000035022194.26189.7013meleagris_gallopavoENSMGAP0000000441796.305291.6466
ENSG00000151461homo_sapiensENSP0000035022197.562993.3176serinus_canariaENSSCAP0000001295397.639793.391
ENSG00000151461homo_sapiensENSP0000035022197.248493.0818parus_majorENSPMJP0000000167994.716790.6585
ENSG00000151461homo_sapiensENSP0000035022196.855392.0597anolis_carolinensisENSACAP0000002987195.35690.6347
ENSG00000151461homo_sapiensENSP0000035022192.21783.805neolamprologus_brichardiENSNBRP000000177119283.6078
ENSG00000151461homo_sapiensENSP0000035022179.245372.956naja_najaENSNNAP0000001998889.839682.7094
ENSG00000151461homo_sapiensENSP0000035022196.698192.3742podarcis_muralisENSPMRP0000001713587.982884.0486
ENSG00000151461homo_sapiensENSP0000035022197.562993.3962geospiza_fortisENSGFOP0000001169197.639793.4697
ENSG00000151461homo_sapiensENSP0000035022197.562993.1604taeniopygia_guttataENSTGUP0000002965296.801992.4337
ENSG00000151461homo_sapiensENSP0000035022191.981184.9843erpetoichthys_calabaricusENSECRP0000001478192.636685.5899
ENSG00000151461homo_sapiensENSP0000035022191.352282.5472kryptolebias_marmoratusENSKMAP0000000144491.640482.8076
ENSG00000151461homo_sapiensENSP0000035022196.540991.9025salvator_merianaeENSSMRP0000001550094.972990.4099
ENSG00000151461homo_sapiensENSP0000035022190.094382.0755oryzias_javanicusENSOJAP0000003735586.752579.031
ENSG00000151461homo_sapiensENSP0000035022191.823983.4119amphilophus_citrinellusENSACIP0000002330191.751883.3464
ENSG00000151461homo_sapiensENSP0000035022191.823983.7264dicentrarchus_labraxENSDLAP0000503397488.484880.6818
ENSG00000151461homo_sapiensENSP0000035022192.138483.6478amphiprion_perculaENSAPEP0000002692691.849583.3856
ENSG00000151461homo_sapiensENSP0000035022131.603828.9308oryzias_sinensisENSOSIP0000003812289.932982.3266
ENSG00000151461homo_sapiensENSP0000035022157.704454.1667pelodiscus_sinensisENSPSIP0000001701892.911487.2152
ENSG00000151461homo_sapiensENSP0000035022195.440391.5094gopherus_evgoodeiENSGEVP0000500563997.042493.0456
ENSG00000151461homo_sapiensENSP0000035022197.091292.6887chelonoidis_abingdoniiENSCABP0000002670695.514391.1833
ENSG00000151461homo_sapiensENSP0000035022192.059783.4119seriola_dumeriliENSSDUP0000002381988.51180.1965
ENSG00000151461homo_sapiensENSP0000035022118.003116.3522cottoperca_gobioENSCGOP0000001016590.513882.2134
ENSG00000151461homo_sapiensENSP0000035022145.518939.3082cottoperca_gobioENSCGOP0000001023070.43860.8273
ENSG00000151461homo_sapiensENSP0000035022197.405793.8679struthio_camelus_australisENSSCUP0000001813295.897892.4149
ENSG00000151461homo_sapiensENSP0000035022197.169893.239anser_brachyrhynchusENSABRP0000001566095.665691.7957
ENSG00000151461homo_sapiensENSP0000035022191.19582.5472gasterosteus_aculeatusENSGACP0000000139991.051882.4176
ENSG00000151461homo_sapiensENSP0000035022185.770477.7516cynoglossus_semilaevisENSCSEP0000000544388.916180.6031
ENSG00000151461homo_sapiensENSP0000035022124.213821.2264cynoglossus_semilaevisENSCSEP0000000542589.795978.7172
ENSG00000151461homo_sapiensENSP0000035022191.902582.6258poecilia_formosaENSPFOP0000001724091.686382.4314
ENSG00000151461homo_sapiensENSP0000035022192.531484.5126myripristis_murdjanENSMMDP0000503056791.881383.9188
ENSG00000151461homo_sapiensENSP0000035022191.745383.0975sander_luciopercaENSSLUP0000001260189.356880.9342
ENSG00000151461homo_sapiensENSP0000035022197.169893.0031strigops_habroptilaENSSHBP0000500500597.246393.0763
ENSG00000151461homo_sapiensENSP0000035022191.981183.4119amphiprion_ocellarisENSAOCP0000001225888.973480.6844
ENSG00000151461homo_sapiensENSP0000035022197.32793.0818terrapene_carolina_triunguisENSTMTP0000001555395.598591.4286
ENSG00000151461homo_sapiensENSP0000035022191.823982.4686hucho_huchoENSHHUP0000005061088.217579.2296
ENSG00000151461homo_sapiensENSP0000035022169.889960.5346hucho_huchoENSHHUP0000004083486.394674.8299
ENSG00000151461homo_sapiensENSP0000035022191.273682.783betta_splendensENSBSLP0000005034490.845182.3944
ENSG00000151461homo_sapiensENSP0000035022192.531483.9623pygocentrus_nattereriENSPNAP0000002467491.099182.6625
ENSG00000151461homo_sapiensENSP0000035022192.059783.5692anabas_testudineusENSATEP0000004053188.64580.4693
ENSG00000151461homo_sapiensENSP000003502218.805036.21069ciona_savignyiENSCSAVP0000001321174.172252.3179
ENSG00000151461homo_sapiensENSP0000035022151.965438.9151ciona_savignyiENSCSAVP0000001323566.365549.6988
ENSG00000151461homo_sapiensENSP0000035022139.386820.9119saccharomyces_cerevisiaeYHR077C46.005524.4261
ENSG00000151461homo_sapiensENSP0000035022189.150981.3679seriola_lalandi_dorsalisENSSLDP0000002163091.525483.5351
ENSG00000151461homo_sapiensENSP0000035022192.295683.805labrus_bergyltaENSLBEP0000002138791.078482.6998
ENSG00000151461homo_sapiensENSP0000035022176.02268.1604labrus_bergyltaENSLBEP0000000094590.289580.9524
ENSG00000151461homo_sapiensENSP0000035022189.622681.2107pundamilia_nyerereiENSPNYP0000002270791.492882.9053
ENSG00000151461homo_sapiensENSP0000035022192.295683.5692mastacembelus_armatusENSMAMP0000002722591.934283.242
ENSG00000151461homo_sapiensENSP0000035022126.100622.6415stegastes_partitusENSSPAP0000001899589.00877.2118
ENSG00000151461homo_sapiensENSP0000035022118.160416.5094stegastes_partitusENSSPAP0000001385391.666783.3333
ENSG00000151461homo_sapiensENSP0000035022179.402571.1478oncorhynchus_tshawytschaENSOTSP0000501973489.857780.516
ENSG00000151461homo_sapiensENSP0000035022189.386880.3459oncorhynchus_tshawytschaENSOTSP0000509377890.669981.4992
ENSG00000151461homo_sapiensENSP0000035022186.949779.0881acanthochromis_polyacanthusENSAPOP0000002969591.028882.7984
ENSG00000151461homo_sapiensENSP0000035022197.405793.3176aquila_chrysaetos_chrysaetosENSACCP0002000548197.482393.391
ENSG00000151461homo_sapiensENSP0000035022191.430882.1541nothobranchius_furzeriENSNFUP0001505184691.215781.9608
ENSG00000151461homo_sapiensENSP0000035022191.430882.4686cyprinodon_variegatusENSCVAP0000000479991.864182.8594
ENSG00000151461homo_sapiensENSP0000035022192.688783.1761denticeps_clupeoidesENSDCDP0000003121892.398182.9154
ENSG00000151461homo_sapiensENSP0000035022191.902583.5692larimichthys_croceaENSLCRP0000505205289.647281.5184
ENSG00000151461homo_sapiensENSP0000035022191.902583.0189takifugu_rubripesENSTRUP0000001862391.614482.7586
ENSG00000151461homo_sapiensENSP0000035022196.147891.6667ficedula_albicollisENSFALP0000001858291.473487.2102
ENSG00000151461homo_sapiensENSP0000035022191.823981.8396hippocampus_comesENSHCOP0000000277090.402580.5728
ENSG00000151461homo_sapiensENSP0000035022184.355377.1226cyprinus_carpio_carpioENSCCRP0000002650678.665771.9208
ENSG00000151461homo_sapiensENSP0000035022186.399478.2233cyprinus_carpio_carpioENSCCRP0000010857576.906969.6291
ENSG00000151461homo_sapiensENSP0000035022197.32793.1604coturnix_japonicaENSCJPP0000500424695.746391.6473
ENSG00000151461homo_sapiensENSP0000035022191.745382.4686poecilia_latipinnaENSPLAP0000002136289.288480.2601
ENSG00000151461homo_sapiensENSP0000035022181.132171.4623sinocyclocheilus_grahamiENSSGRP0000008083886.577276.2584
ENSG00000151461homo_sapiensENSP0000035022180.817672.0912sinocyclocheilus_grahamiENSSGRP0000009962788.013778.5103
ENSG00000151461homo_sapiensENSP0000035022192.21783.805maylandia_zebraENSMZEP000050289449283.6078
ENSG00000151461homo_sapiensENSP0000035022188.286280.8962tetraodon_nigroviridisENSTNIP0000000709290.710883.1179
ENSG00000151461homo_sapiensENSP0000035022189.701380.1887paramormyrops_kingsleyaeENSPKIP0000001102086.37477.2142
ENSG00000151461homo_sapiensENSP0000035022192.21783.8836scleropages_formosusENSSFOP000150373819283.6863
ENSG00000151461homo_sapiensENSP0000035022192.610184.9057leptobrachium_leishanenseENSLLEP0000002335393.864586.0558
ENSG00000151461homo_sapiensENSP0000035022191.509482.7044scophthalmus_maximusENSSMAP0000001251389.814881.1728
ENSG00000151461homo_sapiensENSP0000035022187.893179.717oryzias_melastigmaENSOMEP0000002153289.297180.9904

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0000184involved_in nuclear-transcribed mRNA catabolic process, nonsense-mediated decay3IBA,IMP,TASHomo_sapiens(9606)Process
GO:0001889involved_in liver development1IEAHomo_sapiens(9606)Process
GO:0003723enables RNA binding1IEAHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005634located_in nucleus1IDAHomo_sapiens(9606)Component
GO:0005737is_active_in cytoplasm2IBA,IDAHomo_sapiens(9606)Component
GO:0005829located_in cytosol2IDA,TASHomo_sapiens(9606)Component
GO:0005844part_of polysome1IBAHomo_sapiens(9606)Component
GO:0006406involved_in mRNA export from nucleus1TASHomo_sapiens(9606)Process
GO:0031100involved_in animal organ regeneration1IEAHomo_sapiens(9606)Process
GO:0035145part_of exon-exon junction complex2IBA,IDAHomo_sapiens(9606)Component
GO:0036464located_in cytoplasmic ribonucleoprotein granule1IDAHomo_sapiens(9606)Component
GO:0042162enables telomeric DNA binding1IDAHomo_sapiens(9606)Function
GO:0048471located_in perinuclear region of cytoplasm1IEAHomo_sapiens(9606)Component
GO:0060090enables molecular adaptor activity1EXPHomo_sapiens(9606)Function

Expression