RBPWorld - a comprehensive database of RNA Binding Proteins

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RBP World!

Functions and Diseases

RBP Type	Non-canonical_RBPs
Diseases	N.A.
Drug	N.A.
Main interacting RNAs	N.A.
Moonlighting functions	Metabolic enzyme
Localizations	Stress granucle
BulkPerturb-seq

Description

Ensembl ID	ENSG00000150991	Gene ID	7316	Accession	12468
Symbol	UBC	Alias	HMG20	Full Name	ubiquitin C
Status	Confidence	Length	5765 bases	Strand	Minus strand
Position	12 : 124911604 - 124917368	RNA binding domain	N.A.
Summary	This gene represents a ubiquitin gene, ubiquitin C. The encoded protein is a polyubiquitin precursor. Conjugation of ubiquitin monomers or polymers can lead to various effects within a cell, depending on the residues to which ubiquitin is conjugated. Ubiquitination has been associated with protein degradation, DNA repair, cell cycle regulation, kinase modification, endocytosis, and regulation of other cell signaling pathways. [provided by RefSeq, Aug 2010]

RNA binding domains (RBDs)

Protein	Domain	Pfam ID	E-value	Domain number

RNA binding proteomes (RBPomes)

Pubmed ID	Full Name	Cell	Author	Time	Doi

Literatures on RNA binding capacity

Pubmed ID	Title	Author	Time	Journal
34258055	Identifying a Serum Exosomal-Associated lncRNA/circRNA-miRNA-mRNA Network in Coronary Heart Disease.	Jia Mao	2021-01-01	Cardiology research and practice
27982123	Unraveling gene expression profiles in peripheral motor nerve from amyotrophic lateral sclerosis patients: insights into pathogenesis.	Nilo Riva	2016-12-16	Scientific reports
23776572	Yin Yang 1 intronic binding sequences and splicing elicit intron-mediated enhancement of ubiquitin C gene expression.	Marzia Bianchi	2013-01-01	PloS one
29262570	DanHong injection targets endothelin receptor type B and angiotensin II receptor type 1 in protection against cardiac hypertrophy.	Min-Yu Zhang	2017-11-28	Oncotarget

Transcripts

Name	Transcript ID	bp	Protein	Translation ID
UBC-205	ENST00000536769	3745	685aa	ENSP00000441543
UBC-201	ENST00000339647	2193	685aa	ENSP00000344818
UBC-206	ENST00000538617	1303	305aa	ENSP00000443053
UBC-209	ENST00000541272	582	169aa	ENSP00000440205
UBC-207	ENST00000540351	622	160aa	ENSP00000442800
UBC-210	ENST00000541645	548	155aa	ENSP00000445337
UBC-202	ENST00000535131	563	149aa	ENSP00000439492
UBC-212	ENST00000544481	477	No protein	-
UBC-213	ENST00000546271	559	136aa	ENSP00000438289
UBC-208	ENST00000540700	627	134aa	ENSP00000441238
UBC-203	ENST00000535859	582	122aa	ENSP00000437452
UBC-204	ENST00000536661	624	No protein	-
UBC-211	ENST00000542416	517	61aa	ENSP00000441556

Gene Model

Click here to download ENSG00000150991's gene model file

Pathways

Pathway ID	Pathway Name	Source

Phenotypes

ensgID	Trait	pValue	Pubmed ID

GWAS

ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID

Protein-Protein Interaction (PPI)

Click here to download ENSG00000150991's PPI file

Paralogs

Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Orthologs

Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id

Gene Ontology

Go ID	Go term	No. evidence	Entries	Species	Category
GO:0002020	enables protease binding	1	IPI	Homo_sapiens(9606)	Function
GO:0003723	enables RNA binding	1	HDA	Homo_sapiens(9606)	Function
GO:0005515	enables protein binding	1	IPI	Homo_sapiens(9606)	Function
GO:0005615	located_in extracellular space	1	HDA	Homo_sapiens(9606)	Component
GO:0005634	located_in nucleus	2	HDA,IBA	Homo_sapiens(9606)	Component
GO:0005654	located_in nucleoplasm	1	TAS	Homo_sapiens(9606)	Component
GO:0005737	is_active_in cytoplasm	1	IBA	Homo_sapiens(9606)	Component
GO:0005741	located_in mitochondrial outer membrane	1	TAS	Homo_sapiens(9606)	Component
GO:0005789	located_in endoplasmic reticulum membrane	1	TAS	Homo_sapiens(9606)	Component
GO:0005829	located_in cytosol	1	TAS	Homo_sapiens(9606)	Component
GO:0005886	located_in plasma membrane	1	TAS	Homo_sapiens(9606)	Component
GO:0010008	located_in endosome membrane	1	TAS	Homo_sapiens(9606)	Component
GO:0016567	involved_in protein ubiquitination	1	IBA	Homo_sapiens(9606)	Process
GO:0019941	involved_in modification-dependent protein catabolic process	1	IBA	Homo_sapiens(9606)	Process
GO:0030666	located_in endocytic vesicle membrane	1	TAS	Homo_sapiens(9606)	Component
GO:0031386	enables protein tag activity	1	IBA	Homo_sapiens(9606)	Function
GO:0031625	enables ubiquitin protein ligase binding	1	IBA	Homo_sapiens(9606)	Function
GO:0031982	located_in vesicle	1	HDA	Homo_sapiens(9606)	Component
GO:0070062	located_in extracellular exosome	1	HDA	Homo_sapiens(9606)	Component

Expression