Functions and Diseases

RBP Type Non-canonical_RBPs
Diseases Disease
Drug N.A.
Main interacting RNAs N.A.
Moonlighting functions N.A.
Localizations Nucleoli
BulkPerturb-seq

Description

Ensembl ID ENSG00000149823 Gene ID 738 Accession 1172
Symbol VPS51 Alias FFR;ANG2;ANG3;PCH13;C11orf2;C11orf3 Full Name VPS51 subunit of GARP complex
Status Confidence Length 22539 bases Strand Plus strand
Position 11 : 65089324 - 65111862 RNA binding domain N.A.
Summary This gene encodes a member of the vacuolar protein sorting-associated protein 51 family. The encoded protein is a component of the Golgi-associated retrograde protein complex which acts as a tethering factor for carriers in retrograde transport from the early and late endosomes to the trans-Golgi network. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2012]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal

Transcripts

Name Transcript ID bp Protein Translation ID
VPS51-206 ENST00000528588 723 165aa ENSP00000436134
VPS51-209 ENST00000530773 837 233aa ENSP00000434138
VPS51-205 ENST00000528050 426 No protein -
VPS51-201 ENST00000279281 2661 782aa ENSP00000279281
VPS51-212 ENST00000533656 923 No protein -
VPS51-214 ENST00000534124 1089 163aa ENSP00000436867
VPS51-207 ENST00000529180 1027 334aa ENSP00000435245
VPS51-211 ENST00000533487 600 81aa ENSP00000433579
VPS51-202 ENST00000526578 534 110aa ENSP00000431188
VPS51-215 ENST00000534557 854 255aa ENSP00000435691
VPS51-204 ENST00000527646 2144 No protein -
VPS51-210 ENST00000531146 594 No protein -
VPS51-213 ENST00000533827 1078 72aa ENSP00000434542
VPS51-216 ENST00000534591 1503 No protein -
VPS51-203 ENST00000526856 691 199aa ENSP00000435629
VPS51-208 ENST00000530673 633 99aa ENSP00000431317

Gene Model

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0000938part_of GARP complex3IBA,IDA,NASHomo_sapiens(9606)Component
GO:0003674enables molecular_function1NDHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005730located_in nucleolus1IDAHomo_sapiens(9606)Component
GO:0005794located_in Golgi apparatus1IDAHomo_sapiens(9606)Component
GO:0005829located_in cytosol1IEAHomo_sapiens(9606)Component
GO:0006605involved_in protein targeting1IEAHomo_sapiens(9606)Process
GO:0006914involved_in autophagy1IMPHomo_sapiens(9606)Process
GO:0007030involved_in Golgi organization1IBAHomo_sapiens(9606)Process
GO:0007041involved_in lysosomal transport2IBA,IMPHomo_sapiens(9606)Process
GO:0016020is_active_in membrane3IBA,IDA,TASHomo_sapiens(9606)Component
GO:0032456involved_in endocytic recycling3IBA,IMP,NASHomo_sapiens(9606)Process
GO:0032588located_in trans-Golgi network membrane1TASHomo_sapiens(9606)Component
GO:0042147involved_in retrograde transport, endosome to Golgi4IBA,IDA,IMP,NASHomo_sapiens(9606)Process
GO:0043231located_in intracellular membrane-bounded organelle1IDAHomo_sapiens(9606)Component
GO:0048193involved_in Golgi vesicle transport1IBAHomo_sapiens(9606)Process
GO:0048854involved_in brain morphogenesis1IDAHomo_sapiens(9606)Process
GO:0055037located_in recycling endosome2IDA,NASHomo_sapiens(9606)Component
GO:0090119involved_in vesicle-mediated cholesterol transport1IEAHomo_sapiens(9606)Process
GO:1990745part_of EARP complex3IBA,IDA,IPIHomo_sapiens(9606)Component

Expression