Functions and Diseases

RBP Type Canonical_RBPs
Diseases N.A.
Drug N.A.
Main interacting RNAs N.A.
Moonlighting functions Transmemebrane
Localizations N.A.
BulkPerturb-seq

Description

Ensembl ID ENSG00000149218 Gene ID 23052 Accession 29129
Symbol ENDOD1 Alias NA Full Name endonuclease domain containing 1
Status Confidence Length 42800 bases Strand Plus strand
Position 11 : 95089846 - 95132645 RNA binding domain Endonuclease_NS
Summary Predicted to enable endonuclease activity; metal ion binding activity; and nucleic acid binding activity. Predicted to be involved in nucleic acid phosphodiester bond hydrolysis. Located in extracellular exosome and membrane. [provided by Alliance of Genome Resources, Apr 2022]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000278505 Endonuclease_NS PF01223 2.3e-05 1

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal

Transcripts

Name Transcript ID bp Protein Translation ID
ENDOD1-201 ENST00000278505 4651 500aa ENSP00000278505

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID
28496Job Satisfaction3.1110000E-005-
29612Lipoprotein(a)9.7580000E-005-
38689Platelet Function Tests7.9200000E-010-
38886Platelet Function Tests5.2600000E-006-
38888Platelet Function Tests6.4400000E-006-
38890Platelet Function Tests1.8100000E-006-
38891Platelet Function Tests2.4400000E-007-
38919Platelet Function Tests2.7700000E-011-
40261Platelet Function Tests5.9900000E-011-
40447Platelet Function Tests1.0985900E-005-
40449Platelet Function Tests1.5054100E-005-
40450Platelet Function Tests3.9900000E-006-
40451Platelet Function Tests7.4900000E-007-
40476Platelet Function Tests2.8600000E-011-
46019Platelet Function Tests6.4350132E-006-

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0003676enables nucleic acid binding1IEAHomo_sapiens(9606)Function
GO:0004519enables endonuclease activity1IEAHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005576located_in extracellular region1TASHomo_sapiens(9606)Component
GO:0005829located_in cytosol1TASHomo_sapiens(9606)Component
GO:0016020located_in membrane1HDAHomo_sapiens(9606)Component
GO:0045087involved_in innate immune response1IEAHomo_sapiens(9606)Process
GO:0046872enables metal ion binding1IEAHomo_sapiens(9606)Function
GO:0070062located_in extracellular exosome1HDAHomo_sapiens(9606)Component

Expression