Functions and Diseases

RBP Type Canonical_RBPs
Diseases Cancer Disease
Drug N.A.
Main interacting RNAs N.A.
Moonlighting functions TF
Localizations Nucleoli
BulkPerturb-seq DataSet_02_88

Description

Ensembl ID ENSG00000148516 Gene ID 6935 Accession 11642
Symbol ZEB1 Alias BZP;TCF8;AREB6;FECD6;NIL2A;PPCD3;ZFHEP;ZFHX1A;DELTAEF1 Full Name zinc finger E-box binding homeobox 1
Status Confidence Length 210690 bases Strand Plus strand
Position 10 : 31319125 - 31529814 RNA binding domain zf-met
Summary This gene encodes a zinc finger transcription factor. The encoded protein likely plays a role in transcriptional repression of interleukin 2. Mutations in this gene have been associated with posterior polymorphous corneal dystrophy-3 and late-onset Fuchs endothelial corneal dystrophy. Alternatively spliced transcript variants encoding different isoforms have been described.[provided by RefSeq, Mar 2010]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000444891 zf-met PF12874 2.6e-07 1
ENSP00000444891 zf-met PF12874 2.6e-07 2
ENSP00000452787 zf-met PF12874 3.5e-07 1
ENSP00000452787 zf-met PF12874 3.5e-07 2
ENSP00000391612 zf-met PF12874 3.7e-07 1
ENSP00000391612 zf-met PF12874 3.7e-07 2
ENSP00000319248 zf-met PF12874 4e-07 1
ENSP00000319248 zf-met PF12874 4e-07 2
ENSP00000415961 zf-met PF12874 4.1e-07 1
ENSP00000415961 zf-met PF12874 4.1e-07 2
ENSP00000453970 zf-met PF12874 1.8e-05 1
ENSP00000453970 zf-met PF12874 1.8e-05 2

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal
37525171 Development and validation of a novel prognostic signature based on m6A/m5C/m1A-related genes in hepatocellular carcinoma. Yu Xiao 2023-07-31 BMC medical genomics
32728068 Zeb1 for RCP-induced oral cancer cell invasion and its suppression by resveratrol. Young Jin Kim 2020-07-01 Experimental & molecular medicine
37372954 p53 Affects Zeb1 Interactome of Breast Cancer Stem Cells. E Sergey Parfenyev 2023-06-06 International journal of molecular sciences
35282088 YTHDF3 facilitates triple-negative breast cancer progression and metastasis by stabilizing ZEB1 mRNA in an m6A-dependent manner. Yuxiang Lin 2022-01-01 Annals of translational medicine
29866111 Human antigen R enhances the epithelial-mesenchymal transition via regulation of ZEB-1 in the human airway epithelium. Jian Sun 2018-06-04 Respiratory research
28212533 Upregulation of long non-coding RNA PlncRNA-1 promotes proliferation and induces epithelial-mesenchymal transition in prostate cancer. Yang Jin 2017-04-18 Oncotarget
33364239 Microenvironmental Determinants of Breast Cancer Metastasis: Focus on the Crucial Interplay Between Estrogen and Insulin/Insulin-Like Growth Factor Signaling. Veronica Vella 2020-01-01 Frontiers in cell and developmental biology
32808348 Deficiency of pseudogene UPAT leads to hepatocellular carcinoma progression and forms a positive feedback loop with ZEB1. Leyang Xiang 2020-11-01 Cancer science
28618162 ZEB1-regulated inflammatory phenotype in breast cancer cells. Akihiro Katsura 2017-09-01 Molecular oncology

Transcripts

Name Transcript ID bp Protein Translation ID
ZEB1-205 ENST00000488625 6026 No protein -
ZEB1-216 ENST00000560196 1014 No protein -
ZEB1-208 ENST00000542879 3645 No protein -
ZEB1-221 ENST00000561304 1383 No protein -
ZEB1-201 ENST00000320985 5423 1124aa ENSP00000319248
ZEB1-215 ENST00000559858 2745 No protein -
ZEB1-217 ENST00000560721 3368 1104aa ENSP00000452787
ZEB1-210 ENST00000558440 886 288aa ENSP00000453970
ZEB1-202 ENST00000424869 5937 1125aa ENSP00000415961
ZEB1-203 ENST00000437844 6246 53aa ENSP00000405958
ZEB1-207 ENST00000542815 3217 1057aa ENSP00000444891
ZEB1-213 ENST00000558863 1355 No protein -
ZEB1-220 ENST00000561212 1500 274aa ENSP00000453559
ZEB1-211 ENST00000558655 2773 No protein -
ZEB1-219 ENST00000561061 970 No protein -
ZEB1-214 ENST00000559496 1381 No protein -
ZEB1-204 ENST00000446923 6250 1108aa ENSP00000391612
ZEB1-209 ENST00000557827 877 No protein -
ZEB1-223 ENST00000606671 571 No protein -
ZEB1-222 ENST00000606161 482 No protein -
ZEB1-212 ENST00000558832 570 No protein -
ZEB1-206 ENST00000493835 683 No protein -
ZEB1-218 ENST00000560909 564 No protein -

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID
2104Body Weights and Measures4.88596738298364E-617903300
14737Hemoglobin A, Glycosylated1.8370000E-00519875614
14903Hemoglobin A, Glycosylated8.2010000E-00519875614
14933Hemoglobin A, Glycosylated3.3990000E-00519875614

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000148516homo_sapiensENSP0000048717454.283442.0099homo_sapiensENSP0000041596158.577845.3333

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000148516homo_sapiensENSP0000041596197.777897.4222nomascus_leucogenysENSNLEP0000002202799.547599.1855
ENSG00000148516homo_sapiensENSP0000041596198.933398.8444pan_paniscusENSPPAP0000002489598.757898.669
ENSG00000148516homo_sapiensENSP0000041596199.733399.6444pongo_abeliiENSPPYP0000000254999.733399.6444
ENSG00000148516homo_sapiensENSP0000041596198.933398.8444pan_troglodytesENSPTRP0000006276898.757898.669
ENSG00000148516homo_sapiensENSP0000041596198.311198.3111gorilla_gorillaENSGGOP0000002661699.819599.8195
ENSG00000148516homo_sapiensENSP0000041596190.488986.6667ornithorhynchus_anatinusENSOANP0000005478489.2285.4514
ENSG00000148516homo_sapiensENSP0000041596189.866785.2444sarcophilus_harrisiiENSSHAP0000000615290.348585.7015
ENSG00000148516homo_sapiensENSP0000041596149.511146.9333notamacropus_eugeniiENSMEUP0000000741150.452947.8261
ENSG00000148516homo_sapiensENSP0000041596158.311156.1778choloepus_hoffmanniENSCHOP0000000873970.995768.3983
ENSG00000148516homo_sapiensENSP0000041596194.044491.3778dasypus_novemcinctusENSDNOP0000001297693.877591.2156
ENSG00000148516homo_sapiensENSP0000041596174.044469.9556erinaceus_europaeusENSEEUP0000000583077.129672.8704
ENSG00000148516homo_sapiensENSP0000041596145.422243.3778echinops_telfairiENSETEP0000000947250.09847.8431
ENSG00000148516homo_sapiensENSP0000041596198.133397.3333callithrix_jacchusENSCJAP0000004711597.354596.5608
ENSG00000148516homo_sapiensENSP0000041596198.577898.1333cercocebus_atysENSCATP0000000528098.402897.9592
ENSG00000148516homo_sapiensENSP0000041596199.644499.1111macaca_fascicularisENSMFAP0000003077699.644499.1111
ENSG00000148516homo_sapiensENSP0000041596199.644499.1111macaca_mulattaENSMMUP0000003605099.55699.0231
ENSG00000148516homo_sapiensENSP0000041596198.577897.8667macaca_nemestrinaENSMNEP0000002159598.402897.693
ENSG00000148516homo_sapiensENSP0000041596199.733399.2889papio_anubisENSPANP0000002008499.733399.2889
ENSG00000148516homo_sapiensENSP0000041596198.577898.1333mandrillus_leucophaeusENSMLEP0000003392298.402897.9592
ENSG00000148516homo_sapiensENSP0000041596182.222280tursiops_truncatusENSTTRP0000001118882.589380.3571
ENSG00000148516homo_sapiensENSP0000041596197.511194.9333vulpes_vulpesENSVVUP0000000581997.597995.0178
ENSG00000148516homo_sapiensENSP0000041596190.666786.3111mus_spretusMGP_SPRETEiJ_P004787891.726687.3201
ENSG00000148516homo_sapiensENSP0000041596194.577891.9111equus_asinusENSEASP0000504715593.579690.9411
ENSG00000148516homo_sapiensENSP0000041596192.444488.9778capra_hircusENSCHIP0000001594292.280488.8199
ENSG00000148516homo_sapiensENSP0000041596184.711183.1111loxodonta_africanaENSLAFP0000002038797.843995.9959
ENSG00000148516homo_sapiensENSP0000041596196.622294.2222panthera_leoENSPLOP0000000157695.602593.2278
ENSG00000148516homo_sapiensENSP0000041596195.733393.3333ailuropoda_melanoleucaENSAMEP0000003192197.02794.5946
ENSG00000148516homo_sapiensENSP0000041596191.644487.5556bos_indicus_hybridENSBIXP0000502632287.372983.4746
ENSG00000148516homo_sapiensENSP0000041596186.311181.7778oryctolagus_cuniculusENSOCUP0000000563489.907485.1852
ENSG00000148516homo_sapiensENSP0000041596194.491.6444equus_caballusENSECAP0000008433992.267689.5743
ENSG00000148516homo_sapiensENSP0000041596195.644492.9778canis_lupus_familiarisENSCAFP0084501427897.024394.3192
ENSG00000148516homo_sapiensENSP0000041596197.695.4667panthera_pardusENSPPRP0000000031297.695.4667
ENSG00000148516homo_sapiensENSP0000041596193.066791.1111marmota_marmota_marmotaENSMMMP0000002051996.586794.5572
ENSG00000148516homo_sapiensENSP0000041596191.288.3556balaenoptera_musculusENSBMSP0001000791890.957488.1206
ENSG00000148516homo_sapiensENSP0000041596195.377892.5333cavia_porcellusENSCPOP0000000692295.293192.4512
ENSG00000148516homo_sapiensENSP0000041596197.695.4667felis_catusENSFCAP0000002961197.695.4667
ENSG00000148516homo_sapiensENSP0000041596185.683.1111ursus_americanusENSUAMP0000000216994.690391.9371
ENSG00000148516homo_sapiensENSP0000041596189.155684.8889monodelphis_domesticaENSMODP0000003322389.874585.5735
ENSG00000148516homo_sapiensENSP0000041596192.533388.6222bison_bison_bisonENSBBBP0000000354092.451288.5435
ENSG00000148516homo_sapiensENSP0000041596190.755688.1778monodon_monocerosENSMMNP0001501347091.98289.3694
ENSG00000148516homo_sapiensENSP0000041596193.777889.9556sus_scrofaENSSSCP0000002913293.528489.7163
ENSG00000148516homo_sapiensENSP0000041596194.133391.8222microcebus_murinusENSMICP0000000561795.148292.8122
ENSG00000148516homo_sapiensENSP0000041596192.533389.7778octodon_degusENSODEP0000000319992.946490.1786
ENSG00000148516homo_sapiensENSP0000041596192.444489.2444jaculus_jaculusENSJJAP0000000474093.862890.6137
ENSG00000148516homo_sapiensENSP0000041596192.266788.5333ovis_aries_rambouilletENSOARP0002002276292.102988.3762
ENSG00000148516homo_sapiensENSP000004159619289.0667ursus_maritimusENSUMAP0000002182795.303992.2652
ENSG00000148516homo_sapiensENSP0000041596178.933376.5333ochotona_princepsENSOPRP0000000668091.546488.7629
ENSG00000148516homo_sapiensENSP0000041596190.755688delphinapterus_leucasENSDLEP0000000688992.064989.2696
ENSG00000148516homo_sapiensENSP0000041596191.111188.7111physeter_catodonENSPCTP0000500477791.111188.7111
ENSG00000148516homo_sapiensENSP0000041596190.486.2222mus_caroliMGP_CAROLIEiJ_P004595191.292687.0736
ENSG00000148516homo_sapiensENSP0000041596190.755686.3111mus_musculusENSMUSP0000002508191.405586.9293
ENSG00000148516homo_sapiensENSP0000041596195.293.0667dipodomys_ordiiENSDORP0000001996896.923194.7511
ENSG00000148516homo_sapiensENSP0000041596195.466793.1556mustela_putorius_furoENSMPUP0000001293496.84494.4995
ENSG00000148516homo_sapiensENSP0000041596198.666798.2222aotus_nancymaaeENSANAP0000003676298.666798.2222
ENSG00000148516homo_sapiensENSP0000041596196.896.4444saimiri_boliviensis_boliviensisENSSBOP0000003356898.285297.9242
ENSG00000148516homo_sapiensENSP0000041596163.260.8889vicugna_pacosENSVPAP000000012157976.1111
ENSG00000148516homo_sapiensENSP0000041596199.377899.1111chlorocebus_sabaeusENSCSAP0000000782999.466299.1993
ENSG00000148516homo_sapiensENSP0000041596146.933346.3111tupaia_belangeriENSTBEP0000000756853.604152.8934
ENSG00000148516homo_sapiensENSP0000041596186.133381.7778mesocricetus_auratusENSMAUP0000000073792.905188.2071
ENSG00000148516homo_sapiensENSP0000041596190.755688.0889phocoena_sinusENSPSNP0000000414291.816589.1187
ENSG00000148516homo_sapiensENSP0000041596187.111183.4667camelus_dromedariusENSCDRP0000501267691.503387.6751
ENSG00000148516homo_sapiensENSP0000041596195.288993.8667carlito_syrichtaENSTSYP0000002374797.013695.5656
ENSG00000148516homo_sapiensENSP0000041596195.822293.6889panthera_tigris_altaicaENSPTIP0000000364397.292495.1264
ENSG00000148516homo_sapiensENSP0000041596190.666786.1333rattus_norvegicusENSRNOP0000002433691.974887.376
ENSG00000148516homo_sapiensENSP0000041596195.644493.6prolemur_simusENSPSMP0000001752195.644493.6
ENSG00000148516homo_sapiensENSP0000041596191.288987.2889microtus_ochrogasterENSMOCP0000001373492.941288.8688
ENSG00000148516homo_sapiensENSP0000041596194.577892sorex_araneusENSSARP0000000990496.639494.0054
ENSG00000148516homo_sapiensENSP0000041596190.933386.6667peromyscus_maniculatus_bairdiiENSPEMP0000002188693.084688.717
ENSG00000148516homo_sapiensENSP0000041596190.133385.5111mus_spicilegusENSMSIP0000002305787.640483.1461
ENSG00000148516homo_sapiensENSP0000041596191.111187.0222cricetulus_griseus_chok1gshdENSCGRP0000101669193.436689.2434
ENSG00000148516homo_sapiensENSP0000041596195.555693.5111pteropus_vampyrusENSPVAP0000000951195.896593.8448
ENSG00000148516homo_sapiensENSP0000041596193.244491.2myotis_lucifugusENSMLUP0000000970095.886793.7843
ENSG00000148516homo_sapiensENSP0000041596190.844486.8444vombatus_ursinusENSVURP0001003135291.577187.5448
ENSG00000148516homo_sapiensENSP0000041596197.511194.5778rhinolophus_ferrumequinumENSRFEP0001000597696.908193.9929
ENSG00000148516homo_sapiensENSP0000041596195.466793.3333neovison_visonENSNVIP0000000033996.931494.7653
ENSG00000148516homo_sapiensENSP0000041596192.889.0667bos_taurusENSBTAP0000003865592.635388.9086
ENSG00000148516homo_sapiensENSP0000041596195.733393.0667heterocephalus_glaber_femaleENSHGLP0000004752493.570890.9644
ENSG00000148516homo_sapiensENSP0000041596198.044497.6rhinopithecus_bietiENSRBIP0000001574999.279998.8299
ENSG00000148516homo_sapiensENSP0000041596195.733393.1556canis_lupus_dingoENSCAFP0002003396597.554394.9275
ENSG00000148516homo_sapiensENSP0000041596197.333395.2889sciurus_vulgarisENSSVLP0000501773797.333395.2889
ENSG00000148516homo_sapiensENSP0000041596191.286.6667phascolarctos_cinereusENSPCIP0000005242991.443886.8984
ENSG00000148516homo_sapiensENSP0000041596192.088989.4222procavia_capensisENSPCAP0000000415492.335189.6613
ENSG00000148516homo_sapiensENSP0000041596192.355688.9778nannospalax_galiliENSNGAP0000001514793.519390.099
ENSG00000148516homo_sapiensENSP000004159618.533337.82222bos_grunniensENSBGRP0000003843291.428683.8095
ENSG00000148516homo_sapiensENSP0000041596193.333390.7556chinchilla_lanigeraENSCLAP0000001124094.679992.0649
ENSG00000148516homo_sapiensENSP0000041596192.888989.3333cervus_hanglu_yarkandensisENSCHYP0000003653292.72489.1748
ENSG00000148516homo_sapiensENSP0000041596193.511189.6889catagonus_wagneriENSCWAP0000001830393.097389.292
ENSG00000148516homo_sapiensENSP0000041596196.533394.4889ictidomys_tridecemlineatusENSSTOP0000001468696.705394.6572
ENSG00000148516homo_sapiensENSP0000041596196.444494.6667otolemur_garnettiiENSOGAP0000000749596.530394.7509
ENSG00000148516homo_sapiensENSP0000041596198.666798.4cebus_imitatorENSCCAP0000002615698.754498.4875
ENSG00000148516homo_sapiensENSP0000041596194.844492.9778urocitellus_parryiiENSUPAP0001000409396.82494.9183
ENSG00000148516homo_sapiensENSP0000041596192.622288.8moschus_moschiferusENSMMSP0000002984092.375988.5638
ENSG00000148516homo_sapiensENSP0000041596198.666798.1333rhinopithecus_roxellanaENSRROP0000003726698.491697.9592
ENSG00000148516homo_sapiensENSP0000041596190.311185.6889mus_pahariMGP_PahariEiJ_P003856491.449186.7687
ENSG00000148516homo_sapiensENSP0000041596185.244483.2propithecus_coquereliENSPCOP0000001952695.708693.4132
ENSG00000148516homo_sapiensENSP0000041596146.755632.1778eptatretus_burgeriENSEBUP0000001514937.652125.9127
ENSG00000148516homo_sapiensENSP0000041596174.933363.3778callorhinchus_miliiENSCMIP0000000750571.56260.5263
ENSG00000148516homo_sapiensENSP000004159618072.8latimeria_chalumnaeENSLACP0000001506083.643176.1152
ENSG00000148516homo_sapiensENSP0000041596179.270.8444lepisosteus_oculatusENSLOCP0000000876078.571470.2822
ENSG00000148516homo_sapiensENSP0000041596158.844447.0222clupea_harengusENSCHAP0000002829547.832438.2225
ENSG00000148516homo_sapiensENSP0000041596145.244436.2667clupea_harengusENSCHAP0000001245553.298442.7225
ENSG00000148516homo_sapiensENSP0000041596164.533354.9333danio_rerioENSDARP0000004772367.346957.3284
ENSG00000148516homo_sapiensENSP0000041596154.844443.2danio_rerioENSDARP0000011408251.848740.8403
ENSG00000148516homo_sapiensENSP0000041596163.466752.9778carassius_auratusENSCARP0000003747963.410352.9307
ENSG00000148516homo_sapiensENSP0000041596156.177843.9111carassius_auratusENSCARP0000002675451.973740.625
ENSG00000148516homo_sapiensENSP0000041596153.777842.0444carassius_auratusENSCARP0000002028551.184440.0169
ENSG00000148516homo_sapiensENSP0000041596155.733343.8222carassius_auratusENSCARP0000001527251.818240.7438
ENSG00000148516homo_sapiensENSP0000041596164.266753.6889carassius_auratusENSCARP0000010120166.452255.5147
ENSG00000148516homo_sapiensENSP0000041596165.333354.8444astyanax_mexicanusENSAMXP0000004060465.801355.2372
ENSG00000148516homo_sapiensENSP0000041596159.022245.7778astyanax_mexicanusENSAMXP0000003073849.148838.1199
ENSG00000148516homo_sapiensENSP0000041596156.533344.2667ictalurus_punctatusENSIPUP0000002364950.8839.84
ENSG00000148516homo_sapiensENSP0000041596165.511154.4889ictalurus_punctatusENSIPUP000000166246755.7273
ENSG00000148516homo_sapiensENSP0000041596166.222253.6889esox_luciusENSELUP0000002778462.447650.6287
ENSG00000148516homo_sapiensENSP0000041596163.288951.5556esox_luciusENSELUP0000001152056.240145.8136
ENSG00000148516homo_sapiensENSP0000041596165.244453.7778electrophorus_electricusENSEEEP0000000474965.244453.7778
ENSG00000148516homo_sapiensENSP0000041596155.555643.2889electrophorus_electricusENSEEEP0000004234252.301340.7531
ENSG00000148516homo_sapiensENSP0000041596158.222245.6oncorhynchus_kisutchENSOKIP0000506706949.359538.6586
ENSG00000148516homo_sapiensENSP0000041596167.255.4667oncorhynchus_kisutchENSOKIP0000508753361.916551.1057
ENSG00000148516homo_sapiensENSP0000041596166.044453.0667oncorhynchus_kisutchENSOKIP0000509567654.632443.8971
ENSG00000148516homo_sapiensENSP0000041596165.777853.8667oncorhynchus_kisutchENSOKIP0000509983560.606149.6315
ENSG00000148516homo_sapiensENSP0000041596165.511153.9556oncorhynchus_mykissENSOMYP0000007023261.984951.0513
ENSG00000148516homo_sapiensENSP000004159615.155564.26667oncorhynchus_mykissENSOMYP0000012115269.879557.8313
ENSG00000148516homo_sapiensENSP0000041596167.255.5556oncorhynchus_mykissENSOMYP0000000848662.273551.4827
ENSG00000148516homo_sapiensENSP0000041596161.511148.9778oncorhynchus_mykissENSOMYP0000010057253.312842.4499
ENSG00000148516homo_sapiensENSP0000041596163.288950.2222oncorhynchus_mykissENSOMYP0000006049750.676240.2135
ENSG00000148516homo_sapiensENSP0000041596165.653.1556salmo_salarENSSSAP0000013363057.973346.9756
ENSG00000148516homo_sapiensENSP0000041596167.111155.2salmo_salarENSSSAP0000013095362.551851.4499
ENSG00000148516homo_sapiensENSP0000041596164.088951.7333salmo_salarENSSSAP0000014136858.286247.0493
ENSG00000148516homo_sapiensENSP0000041596166.311154.9333salmo_salarENSSSAP0000004195666.547755.1293
ENSG00000148516homo_sapiensENSP0000041596164.533351.9111salmo_truttaENSSTUP0000007156657.894746.571
ENSG00000148516homo_sapiensENSP0000041596159.288948.1778salmo_truttaENSSTUP0000003403057.748946.9264
ENSG00000148516homo_sapiensENSP0000041596165.777854.1333salmo_truttaENSSTUP0000003007460.855350.0822
ENSG00000148516homo_sapiensENSP0000041596167.555655.4667salmo_truttaENSSTUP0000001264362.346251.1895
ENSG00000148516homo_sapiensENSP000004159616.755565.51111salmo_truttaENSSTUP0000003401862.295150.8197
ENSG00000148516homo_sapiensENSP0000041596149.688939.2889gadus_morhuaENSGMOP0000006395750.77240.1453
ENSG00000148516homo_sapiensENSP0000041596165.955653.9556fundulus_heteroclitusENSFHEP0000000665469.28156.676
ENSG00000148516homo_sapiensENSP000004159616.44.71111fundulus_heteroclitusENSFHEP0000002909664.285747.3214
ENSG00000148516homo_sapiensENSP0000041596151.466740.0889fundulus_heteroclitusENSFHEP0000001217157.554744.831
ENSG00000148516homo_sapiensENSP0000041596156.622243.3778poecilia_reticulataENSPREP0000002899258.120444.5255
ENSG00000148516homo_sapiensENSP0000041596165.688953.6889poecilia_reticulataENSPREP0000001878568.173455.7196
ENSG00000148516homo_sapiensENSP0000041596164.533352.0889xiphophorus_maculatusENSXMAP0000000549267.284554.3095
ENSG00000148516homo_sapiensENSP0000041596157.777844.0889xiphophorus_maculatusENSXMAP0000003966058.505944.6445
ENSG00000148516homo_sapiensENSP0000041596162.755651.2oryzias_latipesENSORLP0000000538268.278555.706
ENSG00000148516homo_sapiensENSP0000041596113.422211.0222cyclopterus_lumpusENSCLMP0000503233768.01855.8559
ENSG00000148516homo_sapiensENSP0000041596131.377823.0222cyclopterus_lumpusENSCLMP0000503233942.94431.5085
ENSG00000148516homo_sapiensENSP0000041596130.222225.7778cyclopterus_lumpusENSCLMP0000501454272.186861.5711
ENSG00000148516homo_sapiensENSP0000041596159.022246.4oreochromis_niloticusENSONIP0000001896358.502245.9912
ENSG00000148516homo_sapiensENSP0000041596164.852.9778oreochromis_niloticusENSONIP0000004976067.940455.5452
ENSG00000148516homo_sapiensENSP0000041596165.333353.5111haplochromis_burtoniENSHBUP0000000028867.493155.2801
ENSG00000148516homo_sapiensENSP0000041596158.933346.4haplochromis_burtoniENSHBUP0000000703458.568946.1131
ENSG00000148516homo_sapiensENSP0000041596166.454.5778astatotilapia_callipteraENSACLP0000001448567.785855.7169
ENSG00000148516homo_sapiensENSP0000041596158.933346.4astatotilapia_callipteraENSACLP0000000471558.414145.9912
ENSG00000148516homo_sapiensENSP0000041596167.111155.8222sparus_aurataENSSAUP0001006164968.761457.1949
ENSG00000148516homo_sapiensENSP0000041596159.733346.6667sparus_aurataENSSAUP0001001497349.339238.5463
ENSG00000148516homo_sapiensENSP0000041596155.644446.7556lates_calcariferENSLCAP0001000646472.706261.0918
ENSG00000148516homo_sapiensENSP000004159614434.1333lates_calcariferENSLCAP0001000593159.423846.0984
ENSG00000148516homo_sapiensENSP000004159616.488894.8lates_calcariferENSLCAP0001000592669.523851.4286
ENSG00000148516homo_sapiensENSP0000041596180.444472.4444xenopus_tropicalisENSXETP0000002548981.752573.6224
ENSG00000148516homo_sapiensENSP0000041596189.333384.1778chrysemys_picta_belliiENSCPBP0000002221991.032685.779
ENSG00000148516homo_sapiensENSP0000041596190.755686.0444sphenodon_punctatusENSSPUP0000000638490.836386.121
ENSG00000148516homo_sapiensENSP0000041596188.883.4667crocodylus_porosusENSCPRP0000501070890.571285.1315
ENSG00000148516homo_sapiensENSP0000041596118.311116.9778laticauda_laticaudataENSLLTP0000001313785.12478.9256
ENSG00000148516homo_sapiensENSP0000041596184.888979.0222notechis_scutatusENSNSUP0000000222086.897280.8917
ENSG00000148516homo_sapiensENSP0000041596184.888978.9333pseudonaja_textilisENSPTXP0000001029186.897280.8007
ENSG00000148516homo_sapiensENSP0000041596189.684.7111anas_platyrhynchos_platyrhynchosENSAPLP0000002322790.974786.0108
ENSG00000148516homo_sapiensENSP0000041596188.883.6444gallus_gallusENSGALP0001000637089.596484.3946
ENSG00000148516homo_sapiensENSP000004159616.133334.8meleagris_gallopavoENSMGAP0000003282267.647152.9412
ENSG00000148516homo_sapiensENSP0000041596185.511180.4444serinus_canariaENSSCAP0000001172389.322284.0297
ENSG00000148516homo_sapiensENSP0000041596185.511180.6222parus_majorENSPMJP0000000713589.156684.0593
ENSG00000148516homo_sapiensENSP0000041596185.678.8444anolis_carolinensisENSACAP0000003680586.678779.838
ENSG00000148516homo_sapiensENSP0000041596151.240.3556neolamprologus_brichardiENSNBRP0000003032960.062647.341
ENSG00000148516homo_sapiensENSP0000041596165.511153.6889neolamprologus_brichardiENSNBRP0000001721166.636554.6112
ENSG00000148516homo_sapiensENSP000004159615.688894.35556neolamprologus_brichardiENSNBRP0000003034164.646549.4949
ENSG00000148516homo_sapiensENSP0000041596184.878.5778naja_najaENSNNAP0000002526686.41380.0725
ENSG00000148516homo_sapiensENSP000004159617.555566.48889podarcis_muralisENSPMRP0000001849071.428661.3445
ENSG00000148516homo_sapiensENSP0000041596186.755681.6889geospiza_fortisENSGFOP0000002193988.888983.6976
ENSG00000148516homo_sapiensENSP0000041596187.911182.4889taeniopygia_guttataENSTGUP0000002511288.779283.3034
ENSG00000148516homo_sapiensENSP0000041596175.288966.3111erpetoichthys_calabaricusENSECRP0000000830979.08569.6545
ENSG00000148516homo_sapiensENSP0000041596157.333344.5333kryptolebias_marmoratusENSKMAP0000002264657.692344.8122
ENSG00000148516homo_sapiensENSP0000041596162.452.0889kryptolebias_marmoratusENSKMAP0000000499566.414455.4399
ENSG00000148516homo_sapiensENSP000004159618882.4salvator_merianaeENSSMRP0000001833988.789283.139
ENSG00000148516homo_sapiensENSP0000041596162.933352.0889oryzias_javanicusENSOJAP0000004139869.005957.115
ENSG00000148516homo_sapiensENSP0000041596157.955644.8oryzias_javanicusENSOJAP0000002225254.378742.035
ENSG00000148516homo_sapiensENSP0000041596167.022255.0222amphilophus_citrinellusENSACIP0000001906669.110956.7369
ENSG00000148516homo_sapiensENSP0000041596149.777838.7556amphilophus_citrinellusENSACIP0000000295458.516245.559
ENSG00000148516homo_sapiensENSP000004159614.977783.82222amphilophus_citrinellusENSACIP0000000297865.116350
ENSG00000148516homo_sapiensENSP0000041596167.255.6444dicentrarchus_labraxENSDLAP0000503630768.169556.4473
ENSG00000148516homo_sapiensENSP0000041596160.533347.4667dicentrarchus_labraxENSDLAP0000506980059.424146.5969
ENSG00000148516homo_sapiensENSP0000041596167.466755.4667amphiprion_perculaENSAPEP0000000477969.125756.8306
ENSG00000148516homo_sapiensENSP0000041596161.422246.9333amphiprion_perculaENSAPEP0000002638960.244146.0331
ENSG00000148516homo_sapiensENSP0000041596158.577848.1778oryzias_sinensisENSOSIP0000004309467.382455.4192
ENSG00000148516homo_sapiensENSP0000041596153.066741.4222oryzias_sinensisENSOSIP0000000052860.060446.8813
ENSG00000148516homo_sapiensENSP0000041596188.883.7333pelodiscus_sinensisENSPSIP0000001049890.900885.7143
ENSG00000148516homo_sapiensENSP0000041596189.155684.1778gopherus_evgoodeiENSGEVP0000502647390.769285.7014
ENSG00000148516homo_sapiensENSP0000041596189.066784.0889chelonoidis_abingdoniiENSCABP0000000510290.678785.6109
ENSG00000148516homo_sapiensENSP0000041596161.066746.6667seriola_dumeriliENSSDUP0000001348159.173145.2196
ENSG00000148516homo_sapiensENSP0000041596166.844455.8222seriola_dumeriliENSSDUP0000000438667.625956.4748
ENSG00000148516homo_sapiensENSP0000041596160.266746.4cottoperca_gobioENSCGOP0000004593759.007845.4308
ENSG00000148516homo_sapiensENSP0000041596166.755654.6667cottoperca_gobioENSCGOP0000005159368.7156.2672
ENSG00000148516homo_sapiensENSP0000041596188.883.5556struthio_camelus_australisENSSCUP0000002049589.596484.3049
ENSG00000148516homo_sapiensENSP0000041596188.355683.3778anser_brachyrhynchusENSABRP0000000134990.942485.8188
ENSG00000148516homo_sapiensENSP0000041596153.955641.1556gasterosteus_aculeatusENSGACP0000002332159.685345.5261
ENSG00000148516homo_sapiensENSP0000041596160.711150.1333gasterosteus_aculeatusENSGACP0000000130168.643256.6834
ENSG00000148516homo_sapiensENSP0000041596165.653.2444cynoglossus_semilaevisENSCSEP0000002225767.458954.7532
ENSG00000148516homo_sapiensENSP0000041596156.533342.9333cynoglossus_semilaevisENSCSEP0000003381561.687746.8477
ENSG00000148516homo_sapiensENSP0000041596154.488941.8667poecilia_formosaENSPFOP0000001412858.492444.9427
ENSG00000148516homo_sapiensENSP0000041596165.777853.6889poecilia_formosaENSPFOP0000001388068.455155.8742
ENSG00000148516homo_sapiensENSP0000041596149.777839.2889poecilia_formosaENSPFOP0000001413862.015548.948
ENSG00000148516homo_sapiensENSP0000041596159.377847.4667myripristis_murdjanENSMMDP0000503742061.172248.9011
ENSG00000148516homo_sapiensENSP0000041596167.911156.1778myripristis_murdjanENSMMDP0000505102566.608555.1003
ENSG00000148516homo_sapiensENSP0000041596166.755655.6444sander_luciopercaENSSLUP0000002183468.272756.9091
ENSG00000148516homo_sapiensENSP0000041596156.444444.0889sander_luciopercaENSSLUP0000003132859.512746.4855
ENSG00000148516homo_sapiensENSP0000041596189.866784.8strigops_habroptilaENSSHBP0000502353191.163286.0234
ENSG00000148516homo_sapiensENSP0000041596161.422246.8444amphiprion_ocellarisENSAOCP0000002519560.244145.9459
ENSG00000148516homo_sapiensENSP0000041596166.044453.8667amphiprion_ocellarisENSAOCP0000001020467.79255.292
ENSG00000148516homo_sapiensENSP0000041596171.466767.3778terrapene_carolina_triunguisENSTMTP0000000241389.932984.7875
ENSG00000148516homo_sapiensENSP0000041596157.244447.3778hucho_huchoENSHHUP0000007950662.463651.6974
ENSG00000148516homo_sapiensENSP0000041596167.822255.6444hucho_huchoENSHHUP0000007052462.746751.4803
ENSG00000148516homo_sapiensENSP0000041596160.711148.8hucho_huchoENSHHUP0000001846954.120443.5024
ENSG00000148516homo_sapiensENSP0000041596167.022255.7333hucho_huchoENSHHUP0000001772263.308152.6448
ENSG00000148516homo_sapiensENSP0000041596159.555646.6667betta_splendensENSBSLP0000004674759.030846.2555
ENSG00000148516homo_sapiensENSP0000041596165.653.4222betta_splendensENSBSLP0000005583267.458954.936
ENSG00000148516homo_sapiensENSP0000041596166.577855.5556pygocentrus_nattereriENSPNAP0000000172567.356156.205
ENSG00000148516homo_sapiensENSP0000041596159.288946.4889pygocentrus_nattereriENSPNAP0000001163051.426440.3238
ENSG00000148516homo_sapiensENSP0000041596166.844455.1111anabas_testudineusENSATEP0000002717868.488256.4663
ENSG00000148516homo_sapiensENSP0000041596159.822246.1333anabas_testudineusENSATEP0000002316059.086945.5663
ENSG00000148516homo_sapiensENSP0000041596158.844444.9778seriola_lalandi_dorsalisENSSLDP0000000773956.436543.1373
ENSG00000148516homo_sapiensENSP0000041596165.866754.7556seriola_lalandi_dorsalisENSSLDP0000002166665.343954.321
ENSG00000148516homo_sapiensENSP0000041596154.044441.6889labrus_bergyltaENSLBEP0000000010947.574336.698
ENSG00000148516homo_sapiensENSP0000041596166.666754.5778labrus_bergyltaENSLBEP0000003578765.33153.4843
ENSG00000148516homo_sapiensENSP0000041596166.454.5778pundamilia_nyerereiENSPNYP0000000995467.785855.7169
ENSG00000148516homo_sapiensENSP0000041596158.666746.2222pundamilia_nyerereiENSPNYP0000002157658.201145.8554
ENSG00000148516homo_sapiensENSP0000041596159.555645.7778mastacembelus_armatusENSMAMP0000001449859.187345.4947
ENSG00000148516homo_sapiensENSP0000041596163.288951.4667mastacembelus_armatusENSMAMP0000006436166.791754.3152
ENSG00000148516homo_sapiensENSP0000041596167.555655.6444stegastes_partitusENSSPAP0000002063367.857155.8929
ENSG00000148516homo_sapiensENSP0000041596160.711146.8444stegastes_partitusENSSPAP0000000643459.912346.2281
ENSG00000148516homo_sapiensENSP0000041596167.111155.5556oncorhynchus_tshawytschaENSOTSP0000507176962.139951.4403
ENSG00000148516homo_sapiensENSP0000041596160.177848.9778oncorhynchus_tshawytschaENSOTSP0000505355160.881349.5504
ENSG00000148516homo_sapiensENSP0000041596163.377851.2889oncorhynchus_tshawytschaENSOTSP0000506816760.067448.6099
ENSG00000148516homo_sapiensENSP0000041596161.422248.8oncorhynchus_tshawytschaENSOTSP0000500722154.323943.1604
ENSG00000148516homo_sapiensENSP0000041596159.822245.6889acanthochromis_polyacanthusENSAPOP0000003411559.24345.2465
ENSG00000148516homo_sapiensENSP0000041596167.288955.5556acanthochromis_polyacanthusENSAPOP0000002434167.892456.0538
ENSG00000148516homo_sapiensENSP0000041596190.133385.3333aquila_chrysaetos_chrysaetosENSACCP0002000185391.351386.4865
ENSG00000148516homo_sapiensENSP0000041596158.488945.8667nothobranchius_furzeriENSNFUP0001504244458.697646.0303
ENSG00000148516homo_sapiensENSP0000041596163.250.6667nothobranchius_furzeriENSNFUP0001503731866.510853.3209
ENSG00000148516homo_sapiensENSP0000041596161.866749.5111cyprinodon_variegatusENSCVAP0000001090568.101854.501
ENSG00000148516homo_sapiensENSP0000041596157.066743.7333cyprinodon_variegatusENSCVAP0000000865358.791245.0549
ENSG00000148516homo_sapiensENSP0000041596156.888945.5111denticeps_clupeoidesENSDCDP0000005192155.99344.7944
ENSG00000148516homo_sapiensENSP0000041596160.444449.8667denticeps_clupeoidesENSDCDP0000006257467.527355.71
ENSG00000148516homo_sapiensENSP0000041596166.311154.8444larimichthys_croceaENSLCRP0000501493768.755856.8664
ENSG00000148516homo_sapiensENSP0000041596160.444446.8444larimichthys_croceaENSLCRP0000506427656.761343.99
ENSG00000148516homo_sapiensENSP0000041596157.866744.8takifugu_rubripesENSTRUP0000005933358.648645.4054
ENSG00000148516homo_sapiensENSP0000041596161.649.8667takifugu_rubripesENSTRUP0000000327367.086254.3078
ENSG00000148516homo_sapiensENSP0000041596186.488981.7778ficedula_albicollisENSFALP0000000742786.258981.5603
ENSG00000148516homo_sapiensENSP0000041596146.311135.5556hippocampus_comesENSHCOP0000000957655.307942.4628
ENSG00000148516homo_sapiensENSP0000041596165.866754.1333hippocampus_comesENSHCOP0000000994269.77457.3446
ENSG00000148516homo_sapiensENSP0000041596160.977850.9333cyprinus_carpio_carpioENSCCRP0000012684463.754653.2528
ENSG00000148516homo_sapiensENSP0000041596155.466743.2cyprinus_carpio_carpioENSCCRP0000015094250.201139.099
ENSG00000148516homo_sapiensENSP000004159616453.7778cyprinus_carpio_carpioENSCCRP0000016509065.994555.4537
ENSG00000148516homo_sapiensENSP0000041596155.288943.5556cyprinus_carpio_carpioENSCCRP0000013981451.193440.3292
ENSG00000148516homo_sapiensENSP0000041596189.866784.9778coturnix_japonicaENSCJPP0000500344190.835685.894
ENSG00000148516homo_sapiensENSP000004159615.244443.82222poecilia_latipinnaENSPLAP0000002547670.238151.1905
ENSG00000148516homo_sapiensENSP0000041596164.622252.3556poecilia_latipinnaENSPLAP0000002204467.627954.7907
ENSG00000148516homo_sapiensENSP0000041596145.688934.8444poecilia_latipinnaENSPLAP0000002548055.930442.6551
ENSG00000148516homo_sapiensENSP0000041596164.355654.2222sinocyclocheilus_grahamiENSSGRP0000008074866.42255.9633
ENSG00000148516homo_sapiensENSP0000041596154.755642.5778sinocyclocheilus_grahamiENSSGRP0000009463551.50540.0502
ENSG00000148516homo_sapiensENSP0000041596164.711153.9556sinocyclocheilus_grahamiENSSGRP0000001490466.423455.3832
ENSG00000148516homo_sapiensENSP0000041596154.666742.9333sinocyclocheilus_grahamiENSSGRP0000006901850.617339.7531
ENSG00000148516homo_sapiensENSP0000041596158.844446.4maylandia_zebraENSMZEP0000503230658.32645.9912
ENSG00000148516homo_sapiensENSP0000041596165.422253.5111maylandia_zebraENSMZEP0000502201667.522955.2294
ENSG00000148516homo_sapiensENSP0000041596158.044447.6444tetraodon_nigroviridisENSTNIP0000000150368.020855.8333
ENSG00000148516homo_sapiensENSP0000041596153.244441.4222tetraodon_nigroviridisENSTNIP0000001078465.751951.1526
ENSG00000148516homo_sapiensENSP0000041596168.444457.9556paramormyrops_kingsleyaeENSPKIP0000003007466.094455.9657
ENSG00000148516homo_sapiensENSP0000041596166.577856.1778paramormyrops_kingsleyaeENSPKIP0000003935971.062659.962
ENSG00000148516homo_sapiensENSP0000041596170.755660.1778scleropages_formosusENSSFOP0001506068169.157358.8184
ENSG00000148516homo_sapiensENSP0000041596171.260.3556scleropages_formosusENSSFOP0001506547369.531258.941
ENSG00000148516homo_sapiensENSP0000041596180.088972leptobrachium_leishanenseENSLLEP0000001116582.509274.1758
ENSG00000148516homo_sapiensENSP0000041596158.133344.9778scophthalmus_maximusENSSMAP0000001474053.387841.3061
ENSG00000148516homo_sapiensENSP0000041596165.333354.0444scophthalmus_maximusENSSMAP0000000545567.617355.9338
ENSG00000148516homo_sapiensENSP0000041596162.933351.5556oryzias_melastigmaENSOMEP0000001982269.343856.8071
ENSG00000148516homo_sapiensENSP0000041596156.533344.1778oryzias_melastigmaENSOMEP0000001340158.998146.1039

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0000122involved_in negative regulation of transcription by RNA polymerase II1IDAHomo_sapiens(9606)Process
GO:0000785part_of chromatin1ISAHomo_sapiens(9606)Component
GO:0000978enables RNA polymerase II cis-regulatory region sequence-specific DNA binding1IBAHomo_sapiens(9606)Function
GO:0000981enables DNA-binding transcription factor activity, RNA polymerase II-specific2IBA,ISAHomo_sapiens(9606)Function
GO:0001227enables DNA-binding transcription repressor activity, RNA polymerase II-specific1IDAHomo_sapiens(9606)Function
GO:0003682enables chromatin binding1IEAHomo_sapiens(9606)Function
GO:0003700enables DNA-binding transcription factor activity1TASHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005634located_in nucleus1IDAHomo_sapiens(9606)Component
GO:0005654located_in nucleoplasm2IDA,TASHomo_sapiens(9606)Component
GO:0005829located_in cytosol1IDAHomo_sapiens(9606)Component
GO:0006357involved_in regulation of transcription by RNA polymerase II1IBAHomo_sapiens(9606)Process
GO:0007389involved_in pattern specification process1IEAHomo_sapiens(9606)Process
GO:0008270enables zinc ion binding1TASHomo_sapiens(9606)Function
GO:0010464involved_in regulation of mesenchymal cell proliferation1IEAHomo_sapiens(9606)Process
GO:0010839involved_in negative regulation of keratinocyte proliferation1IEAHomo_sapiens(9606)Process
GO:0014823involved_in response to activity1IEAHomo_sapiens(9606)Process
GO:0017015involved_in regulation of transforming growth factor beta receptor signaling pathway1IEAHomo_sapiens(9606)Process
GO:0030154involved_in cell differentiation1IEAHomo_sapiens(9606)Process
GO:0030900involved_in forebrain development1IEAHomo_sapiens(9606)Process
GO:0031667involved_in response to nutrient levels1IEAHomo_sapiens(9606)Process
GO:0033081involved_in regulation of T cell differentiation in thymus1IEAHomo_sapiens(9606)Process
GO:0043616involved_in keratinocyte proliferation1IEAHomo_sapiens(9606)Process
GO:0044271involved_in cellular nitrogen compound biosynthetic process1IEAHomo_sapiens(9606)Process
GO:0045602involved_in negative regulation of endothelial cell differentiation1IMPHomo_sapiens(9606)Process
GO:0045666involved_in positive regulation of neuron differentiation1ISSHomo_sapiens(9606)Process
GO:0045892involved_in negative regulation of DNA-templated transcription2IDA,IMPHomo_sapiens(9606)Process
GO:0045944involved_in positive regulation of transcription by RNA polymerase II1IEAHomo_sapiens(9606)Process
GO:0048596involved_in embryonic camera-type eye morphogenesis1IEAHomo_sapiens(9606)Process
GO:0048704involved_in embryonic skeletal system morphogenesis1IEAHomo_sapiens(9606)Process
GO:0048752involved_in semicircular canal morphogenesis1IEAHomo_sapiens(9606)Process
GO:0048856involved_in anatomical structure development1IBAHomo_sapiens(9606)Process
GO:0051150involved_in regulation of smooth muscle cell differentiation1IEAHomo_sapiens(9606)Process
GO:0051216involved_in cartilage development1IEAHomo_sapiens(9606)Process
GO:0070888enables E-box binding1ISSHomo_sapiens(9606)Function
GO:0071230involved_in cellular response to amino acid stimulus1IEAHomo_sapiens(9606)Process
GO:0071560involved_in cellular response to transforming growth factor beta stimulus1IEAHomo_sapiens(9606)Process
GO:0090103involved_in cochlea morphogenesis1IEAHomo_sapiens(9606)Process

Expression