RBPWorld - a comprehensive database of RNA Binding Proteins

Functions and Diseases

RBP Type	Canonical_RBPs
Diseases	CancerSARS-COV-2
Drug	N.A.
Main interacting RNAs	rRNA
Moonlighting functions	TF
Localizations	Nucleoli
BulkPerturb-seq	N.A.

Description

Ensembl ID	ENSG00000148300	Gene ID	57109	Accession	12820
Symbol	REXO4	Alias		Full Name
Status	Confidence	Length	12038 bases	Strand	Minus strand
Position	9 : 133406059 - 133418096	RNA binding domain	RNase_T
Summary

RNA binding domains (RBDs)

Search:

Protein	Domain	Pfam ID	E-value	Domain number
ENSP00000361003	RNase_T	PF00929	1.6e-05	1
ENSP00000361010	RNase_T	PF00929	1.9e-18	1
ENSP00000394229	RNase_T	PF00929	1.3e-05	1

Showing 1 to 3 of 3 entries

RNA binding proteomes (RBPomes)

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Pubmed ID	Full Name	Cell	Author	Time	Doi
22658674	RIC_PMID22658674_Hela_human	Hela	Alfredo Castello	2012 Jun 8	doi: 10.1016/j.cell.2012.04.031.?Epub 2012 May 31
22658674	RIC_PMID22658674_Hs_HeLa	HeLa	Alfredo Castello?	2012 Jun 8	doi: 10.1016/j.cell.2012.04.031.?Epub 2012 May 31
22681889	RIC_PMID22681889_Hs_HEK293	HEK293	Alexander G Baltz	2012 Jun 8	doi: 10.1016/j.molcel.2012.05.021
25173706	Pclap_PMID25173706_Hs_HEK293	HEK293	Katharina Kramer	2014 Oct;11	doi: 10.1038/nmeth.3092.?Epub 2014 Aug 31
27040163	serIC_PMID27040163_Hs_K562.1	K562	Thomas Conrad?	2016 Apr 4	doi: 10.1038/ncomms11212
30352994	eRIC_PMID30352994_Hs_JURKAT.2018	JURKAT	Joel I Perez-Perri	2018 Oct 23	doi: 10.1038/s41467-018-06557-8
30352994	eRIC_PMID30352994_Jurkat_human	Jurkat	Joel I Perez-Perri?	2018 Oct 23	doi: 10.1038/s41467-018-06557-8
30352994	RIC_PMID30352994_Hs_JURKAT.2018	JURKAT	Joel I Perez-Perri	2018 Oct 23	doi: 10.1038/s41467-018-06557-8
30528433	XRNAX_PMID30528433_Hs_HEK293	HEK293	Jakob Trendel	2019 Jan 10	doi: 10.1016/j.cell.2018.11.004.?Epub 2018 Dec 6
30528433	XRNAX_PMID30528433_Hs_HeLa	HeLa	Jakob Trendel	2019 Jan 10	doi: 10.1016/j.cell.2018.11.004.?Epub 2018 Dec 6

Showing 1 to 10 of 18 entries

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Pubmed ID	Title	Author	Time	Journal
No data available in table

Transcripts

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Name	Transcript ID	bp	Protein	Translation ID
REXO4-201	ENST00000371935	1899	250aa	ENSP00000361003
REXO4-202	ENST00000371942	2326	422aa	ENSP00000361010
REXO4-203	ENST00000445916	860	189aa	ENSP00000391534
REXO4-204	ENST00000454825	833	233aa	ENSP00000394229
REXO4-205	ENST00000478037	847	No protein	-
REXO4-206	ENST00000494045	743	No protein	-

Showing 1 to 6 of 6 entries

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Gene Model

Click here to download ENSG00000148300's gene model file

Phenotypes

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ensgID	Trait	pValue	Pubmed ID
15723	Stroke	2.4504353E-004	-

Showing 1 to 1 of 1 entries

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GWAS

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ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID
ENSG00000148300	rs75685923	9	133410109	Squamous cell lung carcinoma	28604730	1.3846594	EFO_0000708
ENSG00000148300	rs3118663	9	133416633	Blood protein levels	28240269	0.3945	EFO_0008011

Showing 1 to 2 of 2 entries

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Protein-Protein Interaction (PPI)

Click here to download ENSG00000148300's PPI file

Paralogs

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Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
ENSG00000148300	homo_sapiens	ENSP00000306565	55.2486	36.4641	homo_sapiens	ENSP00000361010	23.6967	15.6398
ENSG00000148300	homo_sapiens	ENSP00000331944	42.1538	25.5385	homo_sapiens	ENSP00000361010	32.4645	19.6682
ENSG00000148300	homo_sapiens	ENSP00000261377	15.3747	8.26873	homo_sapiens	ENSP00000361010	28.1991	15.1659
ENSG00000148300	homo_sapiens	ENSP00000170168	12.4488	7.37101	homo_sapiens	ENSP00000361010	36.019	21.327
ENSG00000148300	homo_sapiens	ENSP00000357202	39.3768	25.4958	homo_sapiens	ENSP00000361010	32.9384	21.327
ENSG00000148300	homo_sapiens	ENSP00000486065	100	100	homo_sapiens	ENSP00000361010	100	100

Showing 1 to 6 of 6 entries

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Orthologs

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Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
ENSG00000148300	homo_sapiens	ENSP00000361010	98.3412	95.9716	nomascus_leucogenys	ENSNLEP00000015945	98.1087	95.7447
ENSG00000148300	homo_sapiens	ENSP00000361010	90.7583	87.2038	nomascus_leucogenys	ENSNLEP00000047906	95.2736	91.5423
ENSG00000148300	homo_sapiens	ENSP00000361010	99.5261	98.5782	pan_paniscus	ENSPPAP00000009366	99.5261	98.5782
ENSG00000148300	homo_sapiens	ENSP00000361010	98.3412	96.6825	pongo_abelii	ENSPPYP00000022132	98.3412	96.6825
ENSG00000148300	homo_sapiens	ENSP00000361010	99.763	98.8152	pan_troglodytes	ENSPTRP00000042599	99.763	98.8152
ENSG00000148300	homo_sapiens	ENSP00000361010	99.5261	98.8152	gorilla_gorilla	ENSGGOP00000014154	99.5261	98.8152
ENSG00000148300	homo_sapiens	ENSP00000361010	68.4834	56.1611	ornithorhynchus_anatinus	ENSOANP00000047572	63.5165	52.0879
ENSG00000148300	homo_sapiens	ENSP00000361010	68.9573	56.3981	sarcophilus_harrisii	ENSSHAP00000006696	67.6744	55.3488
ENSG00000148300	homo_sapiens	ENSP00000361010	56.1611	46.4455	notamacropus_eugenii	ENSMEUP00000005947	58.9552	48.7562
ENSG00000148300	homo_sapiens	ENSP00000361010	28.91	25.1185	choloepus_hoffmanni	ENSCHOP00000011748	39.2283	34.0836

Showing 1 to 10 of 200 entries

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Gene Ontology

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Go ID	Go term	No. evidence	Entries	Species	Category
GO:0005634	is_active_in nucleus	2	IBA,NAS	Homo_sapiens(9606)	Component
GO:0003690	enables double-stranded DNA binding	1	IDA	Homo_sapiens(9606)	Function
GO:0003697	enables single-stranded DNA binding	1	IDA	Homo_sapiens(9606)	Function
GO:0003723	enables RNA binding	1	HDA	Homo_sapiens(9606)	Function
GO:0004519	enables endonuclease activity	1	IDA	Homo_sapiens(9606)	Function
GO:0004527	enables exonuclease activity	1	IBA	Homo_sapiens(9606)	Function
GO:0005515	enables protein binding	1	IPI	Homo_sapiens(9606)	Function
GO:0005654	located_in nucleoplasm	1	IDA	Homo_sapiens(9606)	Component
GO:0005730	located_in nucleolus	1	IDA	Homo_sapiens(9606)	Component
GO:0006281	involved_in DNA repair	1	IDA	Homo_sapiens(9606)	Process

Showing 1 to 10 of 15 entries

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Welcome to

RBP World!

Functions and Diseases

Description

RNA binding domains (RBDs)

RNA binding proteomes (RBPomes)

Literatures on RNA binding capacity

Transcripts

Gene Model

Pathways

Phenotypes

GWAS

Protein-Protein Interaction (PPI)

Paralogs

Orthologs

Gene Ontology

Expression