RBPWorld - a comprehensive database of RNA Binding Proteins

Functions and Diseases

RBP Type	Canonical_RBPs
Diseases	N.A.
Drug	N.A.
Main interacting RNAs	diverse
Moonlighting functions	N.A.
Localizations	Nucleoli
BulkPerturb-seq	N.A.

Description

Ensembl ID	ENSG00000147905	Gene ID	84186	Accession	26209
Symbol	ZCCHC7	Alias	AIR1;HSPC086	Full Name	zinc finger CCHC-type containing 7
Status	Confidence	Length	237576 bases	Strand	Plus strand
Position	9 : 37120574 - 37358149	RNA binding domain	zf-CCHC
Summary	Enables RNA binding activity. Located in cytosol and nucleolus. [provided by Alliance of Genome Resources, Apr 2022]

RNA binding domains (RBDs)

Search:

Protein	Domain	Pfam ID	E-value	Domain number
ENSP00000337839	zf-CCHC	PF00098	3.9e-06	1
ENSP00000443113	zf-CCHC	PF00098	3.9e-06	1

Showing 1 to 2 of 2 entries

RNA binding proteomes (RBPomes)

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Pubmed ID	Full Name	Cell	Author	Time	Doi
22658674	RIC_PMID22658674_Hs_HeLa	HeLa	Alfredo Castello?	2012 Jun 8	doi: 10.1016/j.cell.2012.04.031.?Epub 2012 May 31
25173706	Pclap_PMID25173706_Hs_HEK293	HEK293	Katharina Kramer	2014 Oct;11	doi: 10.1038/nmeth.3092.?Epub 2014 Aug 31
30352994	eRIC_PMID30352994_Hs_JURKAT.2018	JURKAT	Joel I Perez-Perri	2018 Oct 23	doi: 10.1038/s41467-018-06557-8
30352994	RIC_PMID30352994_Hs_JURKAT.2018	JURKAT	Joel I Perez-Perri	2018 Oct 23	doi: 10.1038/s41467-018-06557-8
30528433	XRNAX_PMID30528433_Hs_HEK293	HEK293	Jakob Trendel	2019 Jan 10	doi: 10.1016/j.cell.2018.11.004.?Epub 2018 Dec 6
30528433	XRNAX_PMID30528433_Hs_HeLa	HeLa	Jakob Trendel	2019 Jan 10	doi: 10.1016/j.cell.2018.11.004.?Epub 2018 Dec 6
30528433	XRNAX_PMID30528433_Hs_MCF7	MCF7	Jakob Trendel	2019 Jan 10	doi: 10.1016/j.cell.2018.11.004.?Epub 2018 Dec 6
30799147	cRIC_PMID30799147._Hs_HEK293	HEK293	Manuel Garcia-Moreno	2019 Apr 4	doi: 10.1016/j.molcel.2019.01.017.?Epub 2019 Feb 21
33235359	RIC_PMID33235359_humanRIC.superset.2021		Fatima Gebauer	2021 Mar	doi: 10.1038/s41576-020-00302-y
33693821	PP.enrichment.RIC_PMID33693821_Hela_human	Hela	Zheng Zhang	2021 Jun 21	doi: 10.1093/nar/gkab156

Showing 1 to 10 of 10 entries

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Literatures on RNA binding capacity

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Pubmed ID	Title	Author	Time	Journal
27474443	A conserved virus-induced cytoplasmic TRAMP-like complex recruits the exosome to target viral RNA for degradation.	M Jerome Molleston	2016-07-15	Genes & development
29768216	The RNA Exosome Adaptor ZFC3H1 Functionally Competes with Nuclear Export Activity to Retain Target Transcripts.	Toomas Silla	2018-05-15	Cell reports

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Transcripts

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Name	Transcript ID	bp	Protein	Translation ID
ZCCHC7-201	ENST00000322831	1219	205aa	ENSP00000316365
ZCCHC7-202	ENST00000336755	2584	543aa	ENSP00000337839
ZCCHC7-203	ENST00000461038	2793	No protein	-
ZCCHC7-204	ENST00000463625	732	No protein	-
ZCCHC7-205	ENST00000481507	903	No protein	-
ZCCHC7-206	ENST00000488607	884	No protein	-
ZCCHC7-207	ENST00000496099	721	No protein	-
ZCCHC7-208	ENST00000497924	699	No protein	-
ZCCHC7-209	ENST00000534928	2828	543aa	ENSP00000443113

Showing 1 to 9 of 9 entries

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Gene Model

Click here to download ENSG00000147905's gene model file

Phenotypes

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ensgID	Trait	pValue	Pubmed ID
12326	Depressive Disorder, Major	5.001E-5	17728769
35224	Platelet Function Tests	1.1532200E-005	-
37701	Platelet Function Tests	6.0100000E-006	-
37723	Platelet Function Tests	3.1900000E-006	-
39987	Platelet Function Tests	1.1062600E-005	-
40010	Platelet Function Tests	3.0643300E-005	-

Showing 1 to 6 of 6 entries

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GWAS

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ensgID	SNP	Chromosome	Position	Trait	PubmedID	Or or BEAT	EFO ID
ENSG00000147905	rs13293465	9	37127681	Body mass index	30595370		EFO_0004340
ENSG00000147905	rs13285624	9	37129499	Cardiovascular disease	30595370		EFO_0000319
ENSG00000147905	rs62535711	9	37174832	Suicidality	30745170	0.105	EFO_0006882
ENSG00000147905	rs12554976	9	37244508	Morning person	30696823	1.0287007	EFO_0008328

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Protein-Protein Interaction (PPI)

Click here to download ENSG00000147905's PPI file

Paralogs

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Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
ENSG00000147905	homo_sapiens	ENSP00000385047	39.1144	18.0812	homo_sapiens	ENSP00000337839	19.5212	9.02394
ENSG00000147905	homo_sapiens	ENSP00000345633	35.5422	24.0964	homo_sapiens	ENSP00000337839	10.8656	7.36648
ENSG00000147905	homo_sapiens	ENSP00000410619	41.8079	25.9887	homo_sapiens	ENSP00000337839	13.628	8.47145

Showing 1 to 3 of 3 entries

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Orthologs

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Ensembl ID	Source				Target
Ensembl ID	Species	Protein ID	Perc_pos	Perc_id	Species	Protein ID	Perc_pos	Perc_id
ENSG00000147905	homo_sapiens	ENSP00000337839	98.5267	97.9742	nomascus_leucogenys	ENSNLEP00000004405	98.7085	98.155
ENSG00000147905	homo_sapiens	ENSP00000337839	76.7956	72.3757	pan_paniscus	ENSPPAP00000008094	93.2886	87.9195
ENSG00000147905	homo_sapiens	ENSP00000337839	62.2468	62.2468	pan_paniscus	ENSPPAP00000030612	99.705	99.705
ENSG00000147905	homo_sapiens	ENSP00000337839	98.7109	98.5267	pongo_abelii	ENSPPYP00000040723	98.893	98.7085
ENSG00000147905	homo_sapiens	ENSP00000337839	99.8158	99.6317	pan_troglodytes	ENSPTRP00000059975	99.8158	99.6317
ENSG00000147905	homo_sapiens	ENSP00000337839	99.4475	99.4475	gorilla_gorilla	ENSGGOP00000028621	99.4475	99.4475
ENSG00000147905	homo_sapiens	ENSP00000337839	70.3499	55.6169	ornithorhynchus_anatinus	ENSOANP00000012076	67.4912	53.3569
ENSG00000147905	homo_sapiens	ENSP00000337839	70.1657	55.8011	sarcophilus_harrisii	ENSSHAP00000024215	70.4251	56.0074
ENSG00000147905	homo_sapiens	ENSP00000337839	41.9889	35.9116	choloepus_hoffmanni	ENSCHOP00000006160	68.4685	58.5586
ENSG00000147905	homo_sapiens	ENSP00000337839	82.1363	74.4015	dasypus_novemcinctus	ENSDNOP00000019644	81.8349	74.1284

Showing 1 to 10 of 205 entries

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Gene Ontology

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Go ID	Go term	No. evidence	Entries	Species	Category
GO:0003723	enables RNA binding	2	HDA,IBA	Homo_sapiens(9606)	Function
GO:0005515	enables protein binding	1	IPI	Homo_sapiens(9606)	Function
GO:0005730	located_in nucleolus	1	IDA	Homo_sapiens(9606)	Component
GO:0005829	located_in cytosol	1	IDA	Homo_sapiens(9606)	Component
GO:0008270	enables zinc ion binding	1	IEA	Homo_sapiens(9606)	Function
GO:0031499	part_of TRAMP complex	1	IBA	Homo_sapiens(9606)	Component
GO:0071031	involved_in nuclear mRNA surveillance of mRNA 3-end processing	1	IBA	Homo_sapiens(9606)	Process
GO:0071035	involved_in nuclear polyadenylation-dependent rRNA catabolic process	1	IBA	Homo_sapiens(9606)	Process
GO:0071036	involved_in nuclear polyadenylation-dependent snoRNA catabolic process	1	IBA	Homo_sapiens(9606)	Process
GO:0071037	involved_in nuclear polyadenylation-dependent snRNA catabolic process	1	IBA	Homo_sapiens(9606)	Process

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Welcome to

RBP World!

Functions and Diseases

Description

RNA binding domains (RBDs)

RNA binding proteomes (RBPomes)

Literatures on RNA binding capacity

Transcripts

Gene Model

Pathways

Phenotypes

GWAS

Protein-Protein Interaction (PPI)

Paralogs

Orthologs

Gene Ontology

Expression