RBP Type
Non-canonical_RBPs
Diseases
SARS-COV-OC43 Dengue Zika
Drug
N.A.
Main interacting RNAs
N.A.
Moonlighting functions
Transmemebrane
Localizations
N.A.
BulkPerturb-seq
N.A.
Ensembl ID ENSG00000147649 Gene ID
92140 Accession
29608
Symbol
MTDH
Alias
3D3;AEG1;AEG-1;LYRIC;LYRIC/3D3
Full Name
metadherin
Status
Confidence
Length
86077 bases
Strand
Plus strand
Position
8 : 97644184 - 97730260
RNA binding domain
N.A.
Summary
Enables NF-kappaB binding activity; double-stranded RNA binding activity; and transcription coactivator activity. Involved in several processes, including lipopolysaccharide-mediated signaling pathway; positive regulation of intracellular signal transduction; and regulation of transcription, DNA-templated. Located in endoplasmic reticulum; nuclear lumen; and perinuclear region of cytoplasm. Implicated in hepatocellular carcinoma. [provided by Alliance of Genome Resources, Apr 2022]
RNA binding domains (RBDs)
Protein
Domain
Pfam ID
E-value
Domain number
RNA binding proteomes (RBPomes)
Pubmed ID
Full Name
Cell
Author
Time
Doi
Literatures on RNA binding capacity
Pubmed ID
Title
Author
Time
Journal
26221589 Human miR-221/222 in Physiological and Atherosclerotic Vascular Remodeling.
A Dmitry Chistiakov
2015-01-01
BioMed research international
22199357 Cytoplasmic Metadherin (MTDH) provides survival advantage under conditions of stress by acting as RNA-binding protein.
Xiangbing Meng
2012-02-10
The Journal of biological chemistry
28341852 Profiling of long non-coding RNAs identifies LINC00958 and LINC01296 as candidate oncogenes in bladder cancer.
Katharina Anna Seitz
2017-03-24
Scientific reports
33962073 TAK1 Is a Novel Target in Hepatocellular Carcinoma and Contributes to Sorafenib Resistance.
Shunjie Xia
2021-01-01
Cellular and molecular gastroenterology and hepatology
31477281 MTDH/AEG-1 downregulation using pristimerin-loaded nanoparticles inhibits Fanconi anemia proteins and increases sensitivity to platinum-based chemotherapy.
Jianling Bi
2019-11-01
Gynecologic oncology
31527591 Metadherin enhances vulnerability of cancer cells to ferroptosis.
Jianling Bi
2019-09-17
Cell death & disease
36499586 RNA-Interference-Mediated miR-122-Based Gene Regulation in Colon Cancer, a Structural In Silico Analysis.
Harsha Ganesan
2022-12-03
International journal of molecular sciences
31054476 Metadherin Is a Prognostic Apoptosis Modulator in Mesothelioma Induced via NF-κB-Mediated Signaling.
Li Zhang
2019-06-01
Translational oncology
25940628 Generation of functionally distinct isoforms of PTBP3 by alternative splicing and translation initiation.
Lit-Yeen Tan
2015-06-23
Nucleic acids research
34244458 Recruitment of endoplasmic reticulum-targeted and cytosolic mRNAs into membrane-associated stress granules.
R Jessica Child
2021-10-01
RNA (New York, N.Y.)
31979093 Phenethyl Isothiocyanate Suppresses Stemness in the Chemo- and Radio-Resistant Triple-Negative Breast Cancer Cell Line MDA-MB-231/IR Via Downregulation of Metadherin.
Thi-Kim Yen Nguyen
2020-01-22
Cancers
Name
Transcript ID
bp
Protein
Translation ID
MTDH-201
ENST00000336273
7662
582aa
ENSP00000338235
MTDH-203
ENST00000519934
2184
526aa
ENSP00000428168
MTDH-206
ENST00000522313
672
224aa
ENSP00000428703
MTDH-202
ENST00000519293
629
60aa
ENSP00000429289
MTDH-204
ENST00000521933
565
188aa
ENSP00000429642
MTDH-205
ENST00000522104
486
No protein
-
Pathway ID
Pathway Name
Source
ensgID
Trait
pValue
Pubmed ID
37339 Platelet Function Tests 2.4367200E-005 - 37345 Platelet Function Tests 3.6370200E-005 - 37351 Platelet Function Tests 2.6556900E-005 - 37371 Platelet Function Tests 2.4367200E-005 - 37377 Platelet Function Tests 3.6370200E-005 - 37383 Platelet Function Tests 2.6556900E-005 - 39684 Platelet Function Tests 1.3747600E-005 - 39690 Platelet Function Tests 1.4674900E-005 - 39693 Platelet Function Tests 1.5596500E-005 - 39694 Platelet Function Tests 1.7476900E-005 - 39718 Platelet Function Tests 5.7300000E-006 - 39726 Platelet Function Tests 4.0700000E-006 - 39729 Platelet Function Tests 4.6000000E-006 - 39730 Platelet Function Tests 4.9200000E-006 - 39782 Platelet Function Tests 4.4600000E-006 - 39792 Platelet Function Tests 4.8400000E-006 - 39795 Platelet Function Tests 6.4200000E-006 - 39797 Platelet Function Tests 6.0200000E-006 -
ensgID SNP Chromosome Position
Trait PubmedID Or or BEAT
EFO ID
Protein-Protein Interaction (PPI)
Ensembl ID
Source
Target
Species
Protein ID
Perc_pos
Perc_id
Species
Protein ID
Perc_pos
Perc_id
ENSG00000147649 homo_sapiens ENSP00000324175 30.6024 15.6627 homo_sapiens ENSP00000338235 21.8213 11.1684
Ensembl ID
Source
Target
Species
Protein ID
Perc_pos
Perc_id
Species
Protein ID
Perc_pos
Perc_id
ENSG00000147649 homo_sapiens ENSP00000338235 99.4845 99.1409 nomascus_leucogenys ENSNLEP00000004519 99.4845 99.1409 ENSG00000147649 homo_sapiens ENSP00000338235 97.4227 96.2199 pan_paniscus ENSPPAP00000012488 100 98.7654 ENSG00000147649 homo_sapiens ENSP00000338235 99.4845 98.9691 pongo_abelii ENSPPYP00000021053 99.6558 99.1394 ENSG00000147649 homo_sapiens ENSP00000338235 100 99.4845 pan_troglodytes ENSPTRP00000034960 100 99.4845 ENSG00000147649 homo_sapiens ENSP00000338235 99.8282 99.6564 gorilla_gorilla ENSGGOP00000035388 94.9346 94.7712 ENSG00000147649 homo_sapiens ENSP00000338235 69.244 59.1065 ornithorhynchus_anatinus ENSOANP00000005841 70.2091 59.9303 ENSG00000147649 homo_sapiens ENSP00000338235 84.1924 75.2577 sarcophilus_harrisii ENSSHAP00000035884 74.8092 66.8702 ENSG00000147649 homo_sapiens ENSP00000338235 44.1581 38.488 notamacropus_eugenii ENSMEUP00000014547 45.2465 39.4366 ENSG00000147649 homo_sapiens ENSP00000338235 89.5189 87.457 choloepus_hoffmanni ENSCHOP00000007361 89.673 87.6076 ENSG00000147649 homo_sapiens ENSP00000338235 93.4708 91.0653 dasypus_novemcinctus ENSDNOP00000033679 88.4553 86.1789 ENSG00000147649 homo_sapiens ENSP00000338235 79.3814 77.1478 erinaceus_europaeus ENSEEUP00000007746 82.3529 80.0357 ENSG00000147649 homo_sapiens ENSP00000338235 86.2543 82.4742 echinops_telfairi ENSETEP00000014107 86.1063 82.3328 ENSG00000147649 homo_sapiens ENSP00000338235 97.4227 96.9072 callithrix_jacchus ENSCJAP00000084329 92.4959 92.0065 ENSG00000147649 homo_sapiens ENSP00000338235 99.3127 98.9691 cercocebus_atys ENSCATP00000025068 94.4444 94.1176 ENSG00000147649 homo_sapiens ENSP00000338235 90.378 88.6598 macaca_fascicularis ENSMFAP00000054236 83.2279 81.6456 ENSG00000147649 homo_sapiens ENSP00000338235 99.1409 98.6254 macaca_mulatta ENSMMUP00000046210 94.281 93.7908 ENSG00000147649 homo_sapiens ENSP00000338235 91.0653 90.8935 macaca_nemestrina ENSMNEP00000018799 99.0654 98.8785 ENSG00000147649 homo_sapiens ENSP00000338235 99.3127 98.6254 papio_anubis ENSPANP00000003233 99.3127 98.6254 ENSG00000147649 homo_sapiens ENSP00000338235 99.3127 98.6254 mandrillus_leucophaeus ENSMLEP00000014629 99.3127 98.6254 ENSG00000147649 homo_sapiens ENSP00000338235 83.3333 81.9588 tursiops_truncatus ENSTTRP00000010453 83.3333 81.9588 ENSG00000147649 homo_sapiens ENSP00000338235 78.6942 75.945 vulpes_vulpes ENSVVUP00000004795 85.1301 82.1561 ENSG00000147649 homo_sapiens ENSP00000338235 94.5017 91.0653 mus_spretus MGP_SPRETEiJ_P0039789 94.9914 91.5371 ENSG00000147649 homo_sapiens ENSP00000338235 95.7045 93.6426 equus_asinus ENSEASP00005004326 90.5691 88.6179 ENSG00000147649 homo_sapiens ENSP00000338235 96.3918 93.4708 capra_hircus ENSCHIP00000022275 96.2264 93.3105 ENSG00000147649 homo_sapiens ENSP00000338235 73.7113 71.134 loxodonta_africana ENSLAFP00000003225 95.3333 92 ENSG00000147649 homo_sapiens ENSP00000338235 96.7354 94.3299 panthera_leo ENSPLOP00000000221 96.7354 94.3299 ENSG00000147649 homo_sapiens ENSP00000338235 96.2199 94.5017 ailuropoda_melanoleuca ENSAMEP00000025204 91.653 90.0164 ENSG00000147649 homo_sapiens ENSP00000338235 96.3918 93.1272 bos_indicus_hybrid ENSBIXP00005005052 91.5171 88.4176 ENSG00000147649 homo_sapiens ENSP00000338235 79.7251 76.1168 oryctolagus_cuniculus ENSOCUP00000033799 85.1376 81.2844 ENSG00000147649 homo_sapiens ENSP00000338235 95.7045 93.6426 equus_caballus ENSECAP00000009021 88.8357 86.9219 ENSG00000147649 homo_sapiens ENSP00000338235 95.189 91.0653 canis_lupus_familiaris ENSCAFP00845024290 94.863 90.7534 ENSG00000147649 homo_sapiens ENSP00000338235 96.7354 94.3299 panthera_pardus ENSPPRP00000002715 96.7354 94.3299 ENSG00000147649 homo_sapiens ENSP00000338235 87.8007 85.7388 marmota_marmota_marmota ENSMMMP00000017723 96.7803 94.5076 ENSG00000147649 homo_sapiens ENSP00000338235 94.8454 92.6117 balaenoptera_musculus ENSBMSP00010020318 94.8454 92.6117 ENSG00000147649 homo_sapiens ENSP00000338235 93.8144 89.5189 cavia_porcellus ENSCPOP00000026836 93.6535 89.3653 ENSG00000147649 homo_sapiens ENSP00000338235 96.7354 94.1581 felis_catus ENSFCAP00000020313 91.9935 89.5425 ENSG00000147649 homo_sapiens ENSP00000338235 95.7045 93.8144 ursus_americanus ENSUAMP00000007822 91.3115 89.5082 ENSG00000147649 homo_sapiens ENSP00000338235 81.0997 72.3368 monodelphis_domestica ENSMODP00000052838 71.2991 63.5952 ENSG00000147649 homo_sapiens ENSP00000338235 79.2096 76.8041 bison_bison_bison ENSBBBP00000004006 80.1739 77.7391 ENSG00000147649 homo_sapiens ENSP00000338235 95.5326 93.4708 monodon_monoceros ENSMMNP00015017034 90.8497 88.8889 ENSG00000147649 homo_sapiens ENSP00000338235 94.6735 91.4089 sus_scrofa ENSSSCP00000064071 89.8858 86.7863 ENSG00000147649 homo_sapiens ENSP00000338235 77.8351 74.2268 microcebus_murinus ENSMICP00000037388 91.3306 87.0968 ENSG00000147649 homo_sapiens ENSP00000338235 85.9107 83.3333 microcebus_murinus ENSMICP00000009642 96.3391 93.4489 ENSG00000147649 homo_sapiens ENSP00000338235 92.7835 88.6598 octodon_degus ENSODEP00000005024 92.7835 88.6598 ENSG00000147649 homo_sapiens ENSP00000338235 95.7045 91.7526 jaculus_jaculus ENSJJAP00000015731 95.8692 91.9105 ENSG00000147649 homo_sapiens ENSP00000338235 96.2199 93.299 ovis_aries_rambouillet ENSOARP00020031583 91.354 88.5807 ENSG00000147649 homo_sapiens ENSP00000338235 77.4914 74.3986 ursus_maritimus ENSUMAP00000023142 85.4167 82.0076 ENSG00000147649 homo_sapiens ENSP00000338235 68.5567 65.1203 ochotona_princeps ENSOPRP00000004581 73.0769 69.4139 ENSG00000147649 homo_sapiens ENSP00000338235 95.5326 93.6426 delphinapterus_leucas ENSDLEP00000003954 90.8497 89.0523 ENSG00000147649 homo_sapiens ENSP00000338235 95.3608 93.1272 physeter_catodon ENSPCTP00005008984 90.6863 88.5621 ENSG00000147649 homo_sapiens ENSP00000338235 94.3299 91.0653 mus_caroli MGP_CAROLIEiJ_P0038011 94.8186 91.5371 ENSG00000147649 homo_sapiens ENSP00000338235 94.5017 91.0653 mus_musculus ENSMUSP00000022865 94.9914 91.5371 ENSG00000147649 homo_sapiens ENSP00000338235 95.189 91.9244 dipodomys_ordii ENSDORP00000004124 95.189 91.9244 ENSG00000147649 homo_sapiens ENSP00000338235 96.5636 94.8454 mustela_putorius_furo ENSMPUP00000008661 89.6332 88.0383 ENSG00000147649 homo_sapiens ENSP00000338235 97.5945 96.9072 aotus_nancymaae ENSANAP00000026499 92.8105 92.1569 ENSG00000147649 homo_sapiens ENSP00000338235 79.5533 78.6942 saimiri_boliviensis_boliviensis ENSSBOP00000023765 95.2675 94.2387 ENSG00000147649 homo_sapiens ENSP00000338235 95.5326 93.1272 vicugna_pacos ENSVPAP00000007683 95.5326 93.1272 ENSG00000147649 homo_sapiens ENSP00000338235 99.3127 98.9691 chlorocebus_sabaeus ENSCSAP00000008565 99.3127 98.9691 ENSG00000147649 homo_sapiens ENSP00000338235 80.0687 76.9759 tupaia_belangeri ENSTBEP00000006096 80.2065 77.1084 ENSG00000147649 homo_sapiens ENSP00000338235 93.1272 88.8316 mesocricetus_auratus ENSMAUP00000001442 93.2874 88.9845 ENSG00000147649 homo_sapiens ENSP00000338235 95.3608 93.299 phocoena_sinus ENSPSNP00000019982 90.6863 88.7255 ENSG00000147649 homo_sapiens ENSP00000338235 95.7045 93.299 camelus_dromedarius ENSCDRP00005031147 91.0131 88.7255 ENSG00000147649 homo_sapiens ENSP00000338235 96.0481 93.8144 carlito_syrichta ENSTSYP00000016386 96.5458 94.3005 ENSG00000147649 homo_sapiens ENSP00000338235 88.1443 85.9107 panthera_tigris_altaica ENSPTIP00000015706 90 87.7193 ENSG00000147649 homo_sapiens ENSP00000338235 94.1581 90.378 rattus_norvegicus ENSRNOP00000077252 77.4011 74.2938 ENSG00000147649 homo_sapiens ENSP00000338235 97.5945 95.189 prolemur_simus ENSPSMP00000016331 97.7625 95.3528 ENSG00000147649 homo_sapiens ENSP00000338235 93.299 89.6907 microtus_ochrogaster ENSMOCP00000008396 93.7824 90.1554 ENSG00000147649 homo_sapiens ENSP00000338235 67.354 64.433 sorex_araneus ENSSARP00000009444 93.1116 89.0736 ENSG00000147649 homo_sapiens ENSP00000338235 95.7045 91.7526 peromyscus_maniculatus_bairdii ENSPEMP00000025440 95.8692 91.9105 ENSG00000147649 homo_sapiens ENSP00000338235 83.1615 80.2405 bos_mutus ENSBMUP00000030787 86.2745 83.2442 ENSG00000147649 homo_sapiens ENSP00000338235 94.5017 90.8935 mus_spicilegus ENSMSIP00000019702 90.312 86.8637 ENSG00000147649 homo_sapiens ENSP00000338235 91.7526 86.5979 cricetulus_griseus_chok1gshd ENSCGRP00001008642 90.971 85.8603 ENSG00000147649 homo_sapiens ENSP00000338235 90.8935 89.1753 pteropus_vampyrus ENSPVAP00000003863 90.8935 89.1753 ENSG00000147649 homo_sapiens ENSP00000338235 96.0481 93.4708 myotis_lucifugus ENSMLUP00000005822 96.2134 93.6317 ENSG00000147649 homo_sapiens ENSP00000338235 84.3643 75.0859 vombatus_ursinus ENSVURP00010008339 77.3228 68.8189 ENSG00000147649 homo_sapiens ENSP00000338235 95.8763 93.9863 rhinolophus_ferrumequinum ENSRFEP00010023565 91.4754 89.6721 ENSG00000147649 homo_sapiens ENSP00000338235 96.5636 94.6735 neovison_vison ENSNVIP00000031615 92.1311 90.3279 ENSG00000147649 homo_sapiens ENSP00000338235 96.3918 93.1272 bos_taurus ENSBTAP00000073866 91.5171 88.4176 ENSG00000147649 homo_sapiens ENSP00000338235 93.9863 90.7216 heterocephalus_glaber_female ENSHGLP00000040697 89.5254 86.4157 ENSG00000147649 homo_sapiens ENSP00000338235 98.9691 98.7972 rhinopithecus_bieti ENSRBIP00000039563 99.1394 98.9673 ENSG00000147649 homo_sapiens ENSP00000338235 95.189 91.0653 canis_lupus_dingo ENSCAFP00020011973 90.228 86.3192 ENSG00000147649 homo_sapiens ENSP00000338235 28.3505 26.9759 sciurus_vulgaris ENSSVLP00005016220 82.9146 78.8945 ENSG00000147649 homo_sapiens ENSP00000338235 96.0481 94.1581 sciurus_vulgaris ENSSVLP00005002565 96.0481 94.1581 ENSG00000147649 homo_sapiens ENSP00000338235 83.8488 75.4296 phascolarctos_cinereus ENSPCIP00000038536 77.5835 69.7933 ENSG00000147649 homo_sapiens ENSP00000338235 80.0687 77.8351 procavia_capensis ENSPCAP00000003478 80.2065 77.969 ENSG00000147649 homo_sapiens ENSP00000338235 95.189 92.268 nannospalax_galili ENSNGAP00000008516 95.5172 92.5862 ENSG00000147649 homo_sapiens ENSP00000338235 96.3918 93.1272 bos_grunniens ENSBGRP00000008595 89.9038 86.859 ENSG00000147649 homo_sapiens ENSP00000338235 86.2543 83.3333 chinchilla_lanigera ENSCLAP00000011432 95.0758 91.8561 ENSG00000147649 homo_sapiens ENSP00000338235 95.7045 92.0962 cervus_hanglu_yarkandensis ENSCHYP00000008721 88.2726 84.9445 ENSG00000147649 homo_sapiens ENSP00000338235 95.189 92.4399 catagonus_wagneri ENSCWAP00000017135 90.5229 87.9085 ENSG00000147649 homo_sapiens ENSP00000338235 96.7354 94.3299 ictidomys_tridecemlineatus ENSSTOP00000004560 96.9019 94.4923 ENSG00000147649 homo_sapiens ENSP00000338235 97.2509 95.3608 otolemur_garnettii ENSOGAP00000001845 96.587 94.7099 ENSG00000147649 homo_sapiens ENSP00000338235 97.4227 97.079 cebus_imitator ENSCCAP00000018967 97.4227 97.079 ENSG00000147649 homo_sapiens ENSP00000338235 96.5636 94.1581 urocitellus_parryii ENSUPAP00010016760 91.9804 89.689 ENSG00000147649 homo_sapiens ENSP00000338235 95.8763 93.1272 moschus_moschiferus ENSMMSP00000002103 91.0277 88.4176 ENSG00000147649 homo_sapiens ENSP00000338235 99.1409 98.9691 rhinopithecus_roxellana ENSRROP00000016855 99.1409 98.9691 ENSG00000147649 homo_sapiens ENSP00000338235 93.9863 90.2062 mus_pahari MGP_PahariEiJ_P0041397 94.4732 90.6736 ENSG00000147649 homo_sapiens ENSP00000338235 97.4227 95.189 propithecus_coquereli ENSPCOP00000006880 97.7586 95.5172 ENSG00000147649 homo_sapiens ENSP00000338235 61.512 45.5326 callorhinchus_milii ENSCMIP00000004547 56.9157 42.1304 ENSG00000147649 homo_sapiens ENSP00000338235 65.4639 52.921 latimeria_chalumnae ENSLACP00000003358 62.8713 50.8251 ENSG00000147649 homo_sapiens ENSP00000338235 62.3711 49.3127 xenopus_tropicalis ENSXETP00000089193 64.8214 51.25 ENSG00000147649 homo_sapiens ENSP00000338235 79.2096 66.8385 chrysemys_picta_bellii ENSCPBP00000008043 73.76 62.24 ENSG00000147649 homo_sapiens ENSP00000338235 70.1031 58.4192 sphenodon_punctatus ENSSPUP00000013374 72.5979 60.4982 ENSG00000147649 homo_sapiens ENSP00000338235 76.1168 62.1993 crocodylus_porosus ENSCPRP00005003893 72.2675 59.0538 ENSG00000147649 homo_sapiens ENSP00000338235 72.8522 59.1065 laticauda_laticaudata ENSLLTP00000003933 65.8385 53.4161 ENSG00000147649 homo_sapiens ENSP00000338235 73.0241 58.7629 notechis_scutatus ENSNSUP00000017333 66.0964 53.1882 ENSG00000147649 homo_sapiens ENSP00000338235 73.0241 58.5911 pseudonaja_textilis ENSPTXP00000007796 66.3027 53.1981 ENSG00000147649 homo_sapiens ENSP00000338235 74.5704 63.0584 anas_platyrhynchos_platyrhynchos ENSAPLP00000028462 68.9984 58.3466 ENSG00000147649 homo_sapiens ENSP00000338235 73.8832 60.9966 gallus_gallus ENSGALP00010015810 69.3548 57.2581 ENSG00000147649 homo_sapiens ENSP00000338235 61.512 50.5155 meleagris_gallopavo ENSMGAP00000012740 70.6114 57.9882 ENSG00000147649 homo_sapiens ENSP00000338235 61.6838 50.8591 serinus_canaria ENSSCAP00000004946 69.5736 57.3643 ENSG00000147649 homo_sapiens ENSP00000338235 74.5704 61.6838 parus_major ENSPMJP00000008708 69.5513 57.5321 ENSG00000147649 homo_sapiens ENSP00000338235 43.6426 35.3952 anolis_carolinensis ENSACAP00000015672 62.716 50.8642 ENSG00000147649 homo_sapiens ENSP00000338235 73.3677 58.7629 naja_naja ENSNNAP00000012534 66.9279 53.605 ENSG00000147649 homo_sapiens ENSP00000338235 74.3986 60.1375 podarcis_muralis ENSPMRP00000033055 68.7302 55.5556 ENSG00000147649 homo_sapiens ENSP00000338235 51.2027 43.9863 geospiza_fortis ENSGFOP00000018633 68.9815 59.2593 ENSG00000147649 homo_sapiens ENSP00000338235 74.7423 62.0275 taeniopygia_guttata ENSTGUP00000034424 69.8234 57.9454 ENSG00000147649 homo_sapiens ENSP00000338235 72.6804 59.2784 salvator_merianae ENSSMRP00000009334 65.8878 53.7383 ENSG00000147649 homo_sapiens ENSP00000338235 64.0893 53.6082 pelodiscus_sinensis ENSPSIP00000016853 75.9674 63.5438 ENSG00000147649 homo_sapiens ENSP00000338235 79.3814 66.323 gopherus_evgoodei ENSGEVP00005004760 73.6842 61.563 ENSG00000147649 homo_sapiens ENSP00000338235 75.0859 62.543 chelonoidis_abingdonii ENSCABP00000009274 72.1122 60.066 ENSG00000147649 homo_sapiens ENSP00000338235 51.89 43.9863 struthio_camelus_australis ENSSCUP00000012982 69.9074 59.2593 ENSG00000147649 homo_sapiens ENSP00000338235 74.7423 63.0584 anser_brachyrhynchus ENSABRP00000000433 69.9357 59.0032 ENSG00000147649 homo_sapiens ENSP00000338235 75.2577 62.543 strigops_habroptila ENSSHBP00005002617 70.305 58.427 ENSG00000147649 homo_sapiens ENSP00000338235 78.866 66.4948 terrapene_carolina_triunguis ENSTMTP00000001470 73.2057 61.7225 ENSG00000147649 homo_sapiens ENSP00000338235 76.2887 64.0893 aquila_chrysaetos_chrysaetos ENSACCP00020003103 71.2681 59.8716 ENSG00000147649 homo_sapiens ENSP00000338235 52.2337 43.1271 ficedula_albicollis ENSFALP00000005926 72.381 59.7619 ENSG00000147649 homo_sapiens ENSP00000338235 73.7113 60.8247 coturnix_japonica ENSCJPP00005000569 69.1936 57.0968 ENSG00000147649 homo_sapiens ENSP00000338235 49.1409 32.3024 leptobrachium_leishanense ENSLLEP00000019723 43.5976 28.6585
Go ID
Go term
No. evidence
Entries
Species
Category
GO:0000122 involved_in negative regulation of transcription by RNA polymerase II 1 IDA Homo_sapiens(9606) Process GO:0001650 located_in fibrillar center 1 IDA Homo_sapiens(9606) Component GO:0003712 enables transcription coregulator activity 1 IBA Homo_sapiens(9606) Function GO:0003713 enables transcription coactivator activity 1 IMP Homo_sapiens(9606) Function GO:0003723 enables RNA binding 1 HDA Homo_sapiens(9606) Function GO:0003725 enables double-stranded RNA binding 1 IDA Homo_sapiens(9606) Function GO:0005515 enables protein binding 1 IPI Homo_sapiens(9606) Function GO:0005634 is_active_in nucleus 2 IBA,IDA Homo_sapiens(9606) Component GO:0005737 located_in cytoplasm 1 IDA Homo_sapiens(9606) Component GO:0005783 located_in endoplasmic reticulum 1 IDA Homo_sapiens(9606) Component GO:0005789 located_in endoplasmic reticulum membrane 1 ISS Homo_sapiens(9606) Component GO:0005923 located_in bicellular tight junction 1 ISS Homo_sapiens(9606) Component GO:0006351 involved_in DNA-templated transcription 1 IEA Homo_sapiens(9606) Process GO:0006357 involved_in regulation of transcription by RNA polymerase II 1 IBA Homo_sapiens(9606) Process GO:0010508 involved_in positive regulation of autophagy 1 IDA Homo_sapiens(9606) Process GO:0016324 located_in apical plasma membrane 1 ISS Homo_sapiens(9606) Component GO:0016604 located_in nuclear body 1 IDA Homo_sapiens(9606) Component GO:0031663 involved_in lipopolysaccharide-mediated signaling pathway 1 IMP Homo_sapiens(9606) Process GO:0031965 located_in nuclear membrane 1 IEA Homo_sapiens(9606) Component GO:0043066 involved_in negative regulation of apoptotic process 1 IDA Homo_sapiens(9606) Process GO:0043123 involved_in positive regulation of I-kappaB kinase/NF-kappaB signaling 1 IDA Homo_sapiens(9606) Process GO:0045766 involved_in positive regulation of angiogenesis 1 IDA Homo_sapiens(9606) Process GO:0045893 involved_in positive regulation of DNA-templated transcription 1 IEA Homo_sapiens(9606) Process GO:0046581 located_in intercellular canaliculus 1 ISS Homo_sapiens(9606) Component GO:0048471 located_in perinuclear region of cytoplasm 1 IDA Homo_sapiens(9606) Component GO:0051059 enables NF-kappaB binding 2 IBA,IPI Homo_sapiens(9606) Function GO:0051092 involved_in positive regulation of NF-kappaB transcription factor activity 1 IDA Homo_sapiens(9606) Process GO:0051897 involved_in positive regulation of protein kinase B signaling 1 IDA Homo_sapiens(9606) Process GO:0061629 enables RNA polymerase II-specific DNA-binding transcription factor binding 1 IPI Homo_sapiens(9606) Function
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