Functions and Diseases

RBP Type Canonical_RBPs
Diseases CancerSARS-COV-OC43FlavivirusesHIVRVSARS-COV-2SINVDengueZika
Drug Drug
Main interacting RNAs rRNA
Moonlighting functions Metabolic enzyme
Localizations N.A.
BulkPerturb-seq N.A.

Description

Ensembl ID ENSG00000147403 Gene ID 6134 Accession 10298
Symbol RPL10 Alias QM;L10;NOV;uL16;AUTSX5;DXS648;MRXS35;DXS648E Full Name ribosomal protein L10
Status Confidence Length 10802 bases Strand Plus strand
Position X : 154398367 - 154409168 RNA binding domain Ribosomal_L16
Summary This gene encodes a ribosomal protein that is a component of the 60S ribosome subunit. The related protein in chicken can bind to c-Jun and can repress c-Jun-mediated transcriptional activation. Some studies have detected an association between variation in this gene and autism spectrum disorders, though others do not detect this relationship. There are multiple pseudogenes of this gene dispersed throughout the genome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]

RNA binding domains (RBDs)

Protein Domain Pfam ID E-value Domain number
ENSP00000388600 Ribosomal_L16 PF00252 1.1e-36 1
ENSP00000341730 Ribosomal_L16 PF00252 1.3e-36 1
ENSP00000358832 Ribosomal_L16 PF00252 1.3e-36 1
ENSP00000385621 Ribosomal_L16 PF00252 2.9e-30 1
ENSP00000398047 Ribosomal_L16 PF00252 4e-17 1
ENSP00000405064 Ribosomal_L16 PF00252 6.9e-17 1
ENSP00000395025 Ribosomal_L16 PF00252 1.4e-16 1
ENSP00000406125 Ribosomal_L16 PF00252 2.2e-14 1

RNA binding proteomes (RBPomes)

Pubmed ID Full Name Cell Author Time Doi

Literatures on RNA binding capacity

Pubmed ID Title Author Time Journal

Transcripts

Name Transcript ID bp Protein Translation ID
RPL10-216 ENST00000492572 1656 No protein -
RPL10-211 ENST00000479366 569 No protein -
RPL10-206 ENST00000436473 657 200aa ENSP00000388600
RPL10-201 ENST00000344746 2278 214aa ENSP00000341730
RPL10-214 ENST00000489200 1519 No protein -
RPL10-215 ENST00000491035 1369 No protein -
RPL10-202 ENST00000369817 2164 214aa ENSP00000358832
RPL10-209 ENST00000458500 585 181aa ENSP00000395025
RPL10-213 ENST00000485196 839 No protein -
RPL10-212 ENST00000482732 1731 No protein -
RPL10-210 ENST00000467168 802 No protein -
RPL10-203 ENST00000406022 748 163aa ENSP00000385621
RPL10-208 ENST00000451365 713 108aa ENSP00000406125
RPL10-207 ENST00000449494 622 28aa ENSP00000407754
RPL10-204 ENST00000427682 457 131aa ENSP00000405064
RPL10-205 ENST00000428169 292 91aa ENSP00000398047

Pathways

Pathway ID Pathway Name Source

Phenotypes

ensgID Trait pValue Pubmed ID

GWAS

ensgIDSNPChromosomePosition TraitPubmedIDOr or BEAT EFO ID

Protein-Protein Interaction (PPI)

Paralogs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000147403homo_sapiensENSP0000029828398.130895.7944homo_sapiensENSP0000035883298.130895.7944

Orthologs

Ensembl ID Source Target
Species Protein ID Perc_pos Perc_id Species Protein ID Perc_pos Perc_id
ENSG00000147403homo_sapiensENSP0000035883289.252388.785gorilla_gorillaENSGGOP0000004580097.948797.4359
ENSG00000147403homo_sapiensENSP0000035883299.532799.0654sarcophilus_harrisiiENSSHAP0000003415899.069898.6047
ENSG00000147403homo_sapiensENSP0000035883297.663695.7944notamacropus_eugeniiENSMEUP0000001169996.759394.9074
ENSG00000147403homo_sapiensENSP0000035883296.261795.3271notamacropus_eugeniiENSMEUP0000001200710099.0291
ENSG00000147403homo_sapiensENSP0000035883298.130897.1963choloepus_hoffmanniENSCHOP0000000752598.130897.1963
ENSG00000147403homo_sapiensENSP0000035883238.78536.4486dasypus_novemcinctusENSDNOP0000001983484.693979.5918
ENSG00000147403homo_sapiensENSP0000035883283.644982.7103erinaceus_europaeusENSEEUP0000000269380.269179.3722
ENSG00000147403homo_sapiensENSP0000035883290.654286.9159capra_hircusENSCHIP0000000499290.654286.9159
ENSG00000147403homo_sapiensENSP00000358832100100ailuropoda_melanoleucaENSAMEP00000027992100100
ENSG00000147403homo_sapiensENSP0000035883293.925290.1869monodelphis_domesticaENSMODP0000003158093.925290.1869
ENSG00000147403homo_sapiensENSP0000035883280.373878.5047bison_bison_bisonENSBBBP0000001583070.781969.1358
ENSG00000147403homo_sapiensENSP0000035883251.401951.4019bison_bison_bisonENSBBBP0000000422151.401951.4019
ENSG00000147403homo_sapiensENSP0000035883272.429970.5607jaculus_jaculusENSJJAP0000001553086.592284.3575
ENSG00000147403homo_sapiensENSP0000035883290.186985.9813ovis_aries_rambouilletENSOARP0002001920090.186985.9813
ENSG00000147403homo_sapiensENSP0000035883277.102874.2991saimiri_boliviensis_boliviensisENSSBOP0000000405992.696689.3258
ENSG00000147403homo_sapiensENSP00000358832100100peromyscus_maniculatus_bairdiiENSPEMP00000016488100100
ENSG00000147403homo_sapiensENSP0000035883297.196396.2617vombatus_ursinusENSVURP0001001954196.744295.814
ENSG00000147403homo_sapiensENSP0000035883278.97276.6355vombatus_ursinusENSVURP0001001143693.888991.1111
ENSG00000147403homo_sapiensENSP0000035883210099.0654vombatus_ursinusENSVURP0001002450410099.0654
ENSG00000147403homo_sapiensENSP0000035883267.289764.486bos_taurusENSBTAP0000007042388.343684.6626
ENSG00000147403homo_sapiensENSP0000035883277.570175.2336phascolarctos_cinereusENSPCIP0000004192592.222289.4444
ENSG00000147403homo_sapiensENSP0000035883210099.0654phascolarctos_cinereusENSPCIP0000003647410099.0654
ENSG00000147403homo_sapiensENSP0000035883298.130896.729phascolarctos_cinereusENSPCIP0000005066098.130896.729
ENSG00000147403homo_sapiensENSP0000035883275.700972.4299nannospalax_galiliENSNGAP0000001927375.348872.093
ENSG00000147403homo_sapiensENSP0000035883280.841172.8972caenorhabditis_elegansF10B5.1.180.841172.8972
ENSG00000147403homo_sapiensENSP0000035883286.448677.1028drosophila_melanogasterFBpp030603984.862475.6881
ENSG00000147403homo_sapiensENSP0000035883272.897263.5514ciona_intestinalisENSCINP0000000822877.227767.3267
ENSG00000147403homo_sapiensENSP0000035883293.925285.9813petromyzon_marinusENSPMAP0000000723793.488485.5814
ENSG00000147403homo_sapiensENSP0000035883289.719684.5794eptatretus_burgeriENSEBUP0000000081375.889371.5415
ENSG00000147403homo_sapiensENSP0000035883241.588839.7196callorhinchus_miliiENSCMIP0000000221472.357769.1057
ENSG00000147403homo_sapiensENSP0000035883286.448680.3738latimeria_chalumnaeENSLACP0000000613686.046580
ENSG00000147403homo_sapiensENSP0000035883298.130893.9252lepisosteus_oculatusENSLOCP0000001907797.674493.4884
ENSG00000147403homo_sapiensENSP0000035883293.457986.9159clupea_harengusENSCHAP0000002093289.686183.4081
ENSG00000147403homo_sapiensENSP0000035883297.196392.0561danio_rerioENSDARP0000012090996.744291.6279
ENSG00000147403homo_sapiensENSP0000035883285.981379.4393carassius_auratusENSCARP0000013020278.632572.6496
ENSG00000147403homo_sapiensENSP0000035883296.261791.1215carassius_auratusENSCARP0000008601795.81490.6977
ENSG00000147403homo_sapiensENSP0000035883281.775775.2336astyanax_mexicanusENSAMXP0000003131197.765489.9441
ENSG00000147403homo_sapiensENSP0000035883297.196391.5888ictalurus_punctatusENSIPUP0000002881496.744291.1628
ENSG00000147403homo_sapiensENSP0000035883295.794488.785esox_luciusENSELUP0000007091495.348888.3721
ENSG00000147403homo_sapiensENSP0000035883297.663692.9907electrophorus_electricusENSEEEP0000001209497.209392.5581
ENSG00000147403homo_sapiensENSP0000035883249.065440.1869oncorhynchus_kisutchENSOKIP0000503042437.530.7143
ENSG00000147403homo_sapiensENSP0000035883255.140251.8692oncorhynchus_mykissENSOMYP0000007723758.128154.6798
ENSG00000147403homo_sapiensENSP0000035883292.523485.514salmo_salarENSSSAP0000005831776.153870.3846
ENSG00000147403homo_sapiensENSP0000035883291.588885.0467salmo_salarENSSSAP0000005832187.111180.8889
ENSG00000147403homo_sapiensENSP0000035883292.990786.4486salmo_truttaENSSTUP0000001403092.129685.6481
ENSG00000147403homo_sapiensENSP0000035883291.588885.0467salmo_truttaENSSTUP0000003028790.740784.2593
ENSG00000147403homo_sapiensENSP0000035883295.794490.6542gadus_morhuaENSGMOP0000002022893.181888.1818
ENSG00000147403homo_sapiensENSP0000035883297.663692.5234fundulus_heteroclitusENSFHEP0000001010897.209392.093
ENSG00000147403homo_sapiensENSP0000035883297.196392.0561poecilia_reticulataENSPREP0000000889696.744291.6279
ENSG00000147403homo_sapiensENSP0000035883281.308476.6355xiphophorus_maculatusENSXMAP0000000481397.206791.6201
ENSG00000147403homo_sapiensENSP0000035883297.663691.5888oryzias_latipesENSORLP0000003401296.313490.3226
ENSG00000147403homo_sapiensENSP0000035883297.663692.9907cyclopterus_lumpusENSCLMP0000504631197.209392.5581
ENSG00000147403homo_sapiensENSP0000035883249.532744.3925oreochromis_niloticusENSONIP0000002982761.271754.9133
ENSG00000147403homo_sapiensENSP0000035883298.130892.9907haplochromis_burtoniENSHBUP0000000088697.674492.5581
ENSG00000147403homo_sapiensENSP0000035883298.130892.9907astatotilapia_callipteraENSACLP0000000065497.674492.5581
ENSG00000147403homo_sapiensENSP0000035883297.663692.5234sparus_aurataENSSAUP0001005585997.209392.093
ENSG00000147403homo_sapiensENSP0000035883298.130892.9907lates_calcariferENSLCAP0001000869097.674492.5581
ENSG00000147403homo_sapiensENSP0000035883289.719684.5794lates_calcariferENSLCAP0001000077297.461991.8782
ENSG00000147403homo_sapiensENSP0000035883298.130892.9907lates_calcariferENSLCAP0001002681797.674492.5581
ENSG00000147403homo_sapiensENSP0000035883298.130892.9907lates_calcariferENSLCAP0001004167697.674492.5581
ENSG00000147403homo_sapiensENSP0000035883298.598196.2617xenopus_tropicalisENSXETP0000002379586.122584.0816
ENSG00000147403homo_sapiensENSP0000035883299.065496.729laticauda_laticaudataENSLLTP0000001136398.604796.2791
ENSG00000147403homo_sapiensENSP0000035883299.065497.1963notechis_scutatusENSNSUP0000002161298.604796.7442
ENSG00000147403homo_sapiensENSP0000035883299.065496.729pseudonaja_textilisENSPTXP0000001133998.604796.2791
ENSG00000147403homo_sapiensENSP0000035883298.130892.9907neolamprologus_brichardiENSNBRP0000000528297.674492.5581
ENSG00000147403homo_sapiensENSP0000035883299.065496.729naja_najaENSNNAP0000002914198.604796.2791
ENSG00000147403homo_sapiensENSP0000035883299.532798.1308podarcis_muralisENSPMRP0000003721099.069897.6744
ENSG00000147403homo_sapiensENSP0000035883262.149558.8785taeniopygia_guttataENSTGUP0000003753246.341543.9024
ENSG00000147403homo_sapiensENSP0000035883299.065494.3925erpetoichthys_calabaricusENSECRP0000002782598.604793.9535
ENSG00000147403homo_sapiensENSP0000035883297.196391.5888kryptolebias_marmoratusENSKMAP0000000664796.744291.1628
ENSG00000147403homo_sapiensENSP0000035883278.97270.5607salvator_merianaeENSSMRP0000001839483.251274.3842
ENSG00000147403homo_sapiensENSP0000035883298.130892.5234oryzias_javanicusENSOJAP0000004821197.674492.093
ENSG00000147403homo_sapiensENSP0000035883295.794490.1869amphilophus_citrinellusENSACIP0000000757187.606882.4786
ENSG00000147403homo_sapiensENSP0000035883296.261790.6542dicentrarchus_labraxENSDLAP0000504965689.565284.3478
ENSG00000147403homo_sapiensENSP0000035883298.130892.9907amphiprion_perculaENSAPEP0000002520197.674492.5581
ENSG00000147403homo_sapiensENSP0000035883297.663692.0561oryzias_sinensisENSOSIP0000002914996.313490.7834
ENSG00000147403homo_sapiensENSP0000035883246.261742.5234seriola_dumeriliENSSDUP0000001430683.193376.4706
ENSG00000147403homo_sapiensENSP0000035883296.72991.1215cottoperca_gobioENSCGOP0000002983496.279190.6977
ENSG00000147403homo_sapiensENSP0000035883287.850583.1776gasterosteus_aculeatusENSGACP0000001730987.03782.4074
ENSG00000147403homo_sapiensENSP0000035883254.672951.8692cynoglossus_semilaevisENSCSEP0000001064592.857188.0952
ENSG00000147403homo_sapiensENSP0000035883297.663692.5234poecilia_formosaENSPFOP0000000129595.433890.411
ENSG00000147403homo_sapiensENSP0000035883298.130893.4579myripristis_murdjanENSMMDP0000503212397.674493.0233
ENSG00000147403homo_sapiensENSP0000035883297.663692.0561sander_luciopercaENSSLUP0000003386597.209391.6279
ENSG00000147403homo_sapiensENSP0000035883298.130895.3271strigops_habroptilaENSSHBP0000500847697.674494.8837
ENSG00000147403homo_sapiensENSP0000035883298.130892.9907amphiprion_ocellarisENSAOCP0000002897197.674492.5581
ENSG00000147403homo_sapiensENSP0000035883295.794488.785hucho_huchoENSHHUP0000005202495.348888.3721
ENSG00000147403homo_sapiensENSP0000035883292.990786.4486hucho_huchoENSHHUP0000000652190.867684.4749
ENSG00000147403homo_sapiensENSP0000035883297.663691.1215betta_splendensENSBSLP0000001573881.640676.1719
ENSG00000147403homo_sapiensENSP0000035883297.663691.5888pygocentrus_nattereriENSPNAP0000000881397.209391.1628
ENSG00000147403homo_sapiensENSP0000035883297.663692.9907anabas_testudineusENSATEP0000003333597.209392.5581
ENSG00000147403homo_sapiensENSP0000035883285.51476.6355ciona_savignyiENSCSAVP0000001907485.915576.9953
ENSG00000147403homo_sapiensENSP0000035883278.97266.3551saccharomyces_cerevisiaeYLR075W76.470664.2534
ENSG00000147403homo_sapiensENSP0000035883297.196392.0561seriola_lalandi_dorsalisENSSLDP0000000087896.744291.6279
ENSG00000147403homo_sapiensENSP0000035883292.990789.2523labrus_bergyltaENSLBEP0000002220297.54993.6274
ENSG00000147403homo_sapiensENSP0000035883297.663692.5234pundamilia_nyerereiENSPNYP0000003194597.209392.093
ENSG00000147403homo_sapiensENSP0000035883296.261790.6542mastacembelus_armatusENSMAMP0000005404881.422976.6798
ENSG00000147403homo_sapiensENSP0000035883281.775776.1682stegastes_partitusENSSPAP0000000065497.765491.0615
ENSG00000147403homo_sapiensENSP0000035883293.457986.4486oncorhynchus_tshawytschaENSOTSP0000508783473.529468.0147
ENSG00000147403homo_sapiensENSP0000035883271.02861.6822oncorhynchus_tshawytschaENSOTSP0000503705777.55167.3469
ENSG00000147403homo_sapiensENSP0000035883298.130892.9907acanthochromis_polyacanthusENSAPOP0000000636897.674492.5581
ENSG00000147403homo_sapiensENSP0000035883297.663692.5234nothobranchius_furzeriENSNFUP0001501748497.209392.093
ENSG00000147403homo_sapiensENSP0000035883297.663692.5234cyprinodon_variegatusENSCVAP0000002610297.209392.093
ENSG00000147403homo_sapiensENSP0000035883296.72991.5888denticeps_clupeoidesENSDCDP0000002432596.279191.1628
ENSG00000147403homo_sapiensENSP0000035883258.411251.4019larimichthys_croceaENSLCRP0000504941666.844958.8235
ENSG00000147403homo_sapiensENSP0000035883298.130892.0561takifugu_rubripesENSTRUP0000006304097.674491.6279
ENSG00000147403homo_sapiensENSP0000035883297.663691.1215hippocampus_comesENSHCOP0000002481497.209390.6977
ENSG00000147403homo_sapiensENSP0000035883296.72991.5888cyprinus_carpio_carpioENSCCRP0000003719487.711983.0508
ENSG00000147403homo_sapiensENSP0000035883293.457986.9159cyprinus_carpio_carpioENSCCRP0000003716992.592686.1111
ENSG00000147403homo_sapiensENSP0000035883245.794442.9907coturnix_japonicaENSCJPP0000502394344.545541.8182
ENSG00000147403homo_sapiensENSP0000035883297.663692.5234poecilia_latipinnaENSPLAP0000002837897.209392.093
ENSG00000147403homo_sapiensENSP0000035883291.588885.0467sinocyclocheilus_grahamiENSSGRP0000004729793.333386.6667
ENSG00000147403homo_sapiensENSP0000035883295.794490.1869sinocyclocheilus_grahamiENSSGRP0000004158578.544173.9464
ENSG00000147403homo_sapiensENSP000003588325045.3271maylandia_zebraENSMZEP0000503759773.793166.8966
ENSG00000147403homo_sapiensENSP0000035883298.130892.9907maylandia_zebraENSMZEP0000503551397.674492.5581
ENSG00000147403homo_sapiensENSP0000035883298.130892.0561tetraodon_nigroviridisENSTNIP0000000586897.674491.6279
ENSG00000147403homo_sapiensENSP0000035883298.130892.9907paramormyrops_kingsleyaeENSPKIP0000002232197.674492.5581
ENSG00000147403homo_sapiensENSP0000035883297.663692.0561paramormyrops_kingsleyaeENSPKIP0000000925597.209391.6279
ENSG00000147403homo_sapiensENSP0000035883297.663693.4579scleropages_formosusENSSFOP0001501747597.209393.0233
ENSG00000147403homo_sapiensENSP0000035883298.130893.4579scleropages_formosusENSSFOP0001501746297.674493.0233
ENSG00000147403homo_sapiensENSP0000035883283.177680.8411leptobrachium_leishanenseENSLLEP0000000260752.046850.5848
ENSG00000147403homo_sapiensENSP0000035883297.663692.9907scophthalmus_maximusENSSMAP0000004400997.209392.5581
ENSG00000147403homo_sapiensENSP0000035883298.130892.5234oryzias_melastigmaENSOMEP0000002858889.361784.2553

Gene Ontology

Go ID Go term No. evidence Entries Species Category
GO:0000027involved_in ribosomal large subunit assembly1IBAHomo_sapiens(9606)Process
GO:0000122involved_in negative regulation of transcription by RNA polymerase II1IMPHomo_sapiens(9606)Process
GO:0002181involved_in cytoplasmic translation1ICHomo_sapiens(9606)Process
GO:0003723enables RNA binding1HDAHomo_sapiens(9606)Function
GO:0003735enables structural constituent of ribosome4IBA,IDA,IMP,NASHomo_sapiens(9606)Function
GO:0005515enables protein binding1IPIHomo_sapiens(9606)Function
GO:0005634located_in nucleus1IDAHomo_sapiens(9606)Component
GO:0005783located_in endoplasmic reticulum1IDAHomo_sapiens(9606)Component
GO:0005790colocalizes_with smooth endoplasmic reticulum1IDAHomo_sapiens(9606)Component
GO:0005829located_in cytosol2IDA,TASHomo_sapiens(9606)Component
GO:0006412acts_upstream_of_or_within translation2IC,NASHomo_sapiens(9606)Process
GO:0006417involved_in regulation of translation1IMPHomo_sapiens(9606)Process
GO:0016020located_in membrane1HDAHomo_sapiens(9606)Component
GO:0022625part_of cytosolic large ribosomal subunit3HDA,IBA,IDAHomo_sapiens(9606)Component
GO:0022626located_in cytosolic ribosome1IDAHomo_sapiens(9606)Component
GO:0032991part_of protein-containing complex1IDAHomo_sapiens(9606)Component
GO:0043066involved_in negative regulation of apoptotic process1IMPHomo_sapiens(9606)Process
GO:0045182enables translation regulator activity1IMPHomo_sapiens(9606)Function
GO:1990403involved_in embryonic brain development1IMPHomo_sapiens(9606)Process

Expression